메뉴 건너뛰기




Volumn 13, Issue 8, 2007, Pages 353-361

From traditional Chinese medicine to rational cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

AGRIMOPHOL; AJMALICINE; ALLYL ISOTHIOCYANATE; ANDROGRAPHOLIDE; ARECOLINE; ARTESUNATE; ASIATICOSIDE; BERBERINE; CAFFEINE; CAMPTOTHECIN DERIVATIVE; CATECHIN; COCAINE; CODEINE; CURCUMIN; DESERPIDINE; DESLANOSIDE; DIGITOXIN; DIGOXIN; ESCIN; ESCULETIN; KAINIC ACID; MORPHINE; NATURAL PRODUCT; PAPAVERINE; SALICIN; SCOPOLAMINE; SENNOSIDE; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCA ALKALOID;

EID: 34547179813     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2007.07.001     Document Type: Review
Times cited : (475)

References (77)
  • 4
    • 34250104703 scopus 로고
    • Plant breeding: importance of plant secondary metabolites for protection against pathogens and herbivores
    • Wink M. Plant breeding: importance of plant secondary metabolites for protection against pathogens and herbivores. Theor. Appl. Genet. 75 (1988) 225-233
    • (1988) Theor. Appl. Genet. , vol.75 , pp. 225-233
    • Wink, M.1
  • 5
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • Newman D.J., and Cragg G.M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 70 (2007) 461-477
    • (2007) J. Nat. Prod. , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 6
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: camptothecins and beyond
    • Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat. Rev. Cancer 6 (2006) 789-802
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 7
    • 33749658088 scopus 로고    scopus 로고
    • Topoisomerase enzymes as therapeutic targets for cancer chemotherapy
    • Giles G.I., and Sharma R.P. Topoisomerase enzymes as therapeutic targets for cancer chemotherapy. Med. Chem. 1 (2005) 383-394
    • (2005) Med. Chem. , vol.1 , pp. 383-394
    • Giles, G.I.1    Sharma, R.P.2
  • 9
    • 33646556730 scopus 로고    scopus 로고
    • The spindle assembly checkpoint: preventing chromosome mis-segregation during mitosis and meiosis
    • Malmanche N., et al. The spindle assembly checkpoint: preventing chromosome mis-segregation during mitosis and meiosis. FEBS Lett. 580 (2006) 2888-2895
    • (2006) FEBS Lett. , vol.580 , pp. 2888-2895
    • Malmanche, N.1
  • 10
    • 0036086184 scopus 로고    scopus 로고
    • Novel aspects of natural and modified vinca alkaloids
    • Duflos A., et al. Novel aspects of natural and modified vinca alkaloids. Curr. Med. Chem. Anticancer Agents 2 (2002) 55-70
    • (2002) Curr. Med. Chem. Anticancer Agents , vol.2 , pp. 55-70
    • Duflos, A.1
  • 11
    • 0033734430 scopus 로고    scopus 로고
    • Enhanced paclitaxel production induced by the combination of elicitors in cell suspension cultures of Taxus chinensis
    • Zhang C.H., et al. Enhanced paclitaxel production induced by the combination of elicitors in cell suspension cultures of Taxus chinensis. Biotechnol. Lett. 22 (2000) 1561-1564
    • (2000) Biotechnol. Lett. , vol.22 , pp. 1561-1564
    • Zhang, C.H.1
  • 12
    • 0035990903 scopus 로고    scopus 로고
    • Toward the rational design of protein kinase casein kinase-2 inhibitors
    • Sarno S., et al. Toward the rational design of protein kinase casein kinase-2 inhibitors. Pharmacol. Ther. 93 (2002) 159-168
    • (2002) Pharmacol. Ther. , vol.93 , pp. 159-168
    • Sarno, S.1
  • 13
    • 33947706896 scopus 로고    scopus 로고
    • Diagnosis and therapy of oral squamous cell carcinoma
    • Konkimalla V.B., et al. Diagnosis and therapy of oral squamous cell carcinoma. Expert Rev. Anticancer Ther. 7 (2007) 317-329
    • (2007) Expert Rev. Anticancer Ther. , vol.7 , pp. 317-329
    • Konkimalla, V.B.1
  • 14
    • 34250310936 scopus 로고    scopus 로고
    • Telomerase and telomere dynamics in ageing and cancer: current status and future directions
    • Sampedro Camarena F., et al. Telomerase and telomere dynamics in ageing and cancer: current status and future directions. Clin. Transl. Oncol. 9 (2007) 145-154
    • (2007) Clin. Transl. Oncol. , vol.9 , pp. 145-154
    • Sampedro Camarena, F.1
  • 15
    • 34247115962 scopus 로고    scopus 로고
    • Telomeres and telomerase as targets for cancer therapy
    • Zimmermann S., and Martens U.M. Telomeres and telomerase as targets for cancer therapy. Cell. Mol. Life Sci. 64 (2007) 906-921
    • (2007) Cell. Mol. Life Sci. , vol.64 , pp. 906-921
    • Zimmermann, S.1    Martens, U.M.2
  • 16
    • 0036178169 scopus 로고    scopus 로고
    • In vitro modulation of telomerase activity, telomere length and cell cycle in MKN45 cells by verbascoside
    • Zhang F., et al. In vitro modulation of telomerase activity, telomere length and cell cycle in MKN45 cells by verbascoside. Planta Med. 68 (2002) 115-118
    • (2002) Planta Med. , vol.68 , pp. 115-118
    • Zhang, F.1
  • 17
    • 31844434032 scopus 로고    scopus 로고
    • Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells
    • Guo Q.L., et al. Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells. Life Sci. 78 (2006) 1238-1245
    • (2006) Life Sci. , vol.78 , pp. 1238-1245
    • Guo, Q.L.1
  • 19
    • 84938095333 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) inhibition-a critical review
    • Moreira I.S., et al. Vascular endothelial growth factor (VEGF) inhibition-a critical review. Anticancer Agents Med. Chem. 7 (2007) 223-245
    • (2007) Anticancer Agents Med. Chem. , vol.7 , pp. 223-245
    • Moreira, I.S.1
  • 20
    • 1642556787 scopus 로고    scopus 로고
    • Capsaicin inhibits in vitro and in vivo angiogenesis
    • Min J.K., et al. Capsaicin inhibits in vitro and in vivo angiogenesis. Cancer Res. 64 (2004) 644-651
    • (2004) Cancer Res. , vol.64 , pp. 644-651
    • Min, J.K.1
  • 21
    • 24044455371 scopus 로고    scopus 로고
    • The anti-angiogenic effect of sinomenine
    • Kok T.W., et al. The anti-angiogenic effect of sinomenine. Angiogenesis 8 (2005) 3-12
    • (2005) Angiogenesis , vol.8 , pp. 3-12
    • Kok, T.W.1
  • 22
    • 0034666133 scopus 로고    scopus 로고
    • Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum
    • Shenai B.R., et al. Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum. J. Biol. Chem. 275 (2000) 29000-29010
    • (2000) J. Biol. Chem. , vol.275 , pp. 29000-29010
    • Shenai, B.R.1
  • 23
    • 7944222115 scopus 로고    scopus 로고
    • Artemisinins: mechanisms of action and potential for resistance
    • Krishna S., et al. Artemisinins: mechanisms of action and potential for resistance. Drug Resist. Updat. 7 (2004) 233-244
    • (2004) Drug Resist. Updat. , vol.7 , pp. 233-244
    • Krishna, S.1
  • 24
    • 0034913428 scopus 로고    scopus 로고
    • Immunoprecipitation of [(3)H]dihydroartemisinin translationally controlled tumor protein (TCTP) adducts from Plasmodium falciparum-infected erythrocytes by using anti-TCTP antibodies
    • Bhisutthibhan J., and Meshnick S.R. Immunoprecipitation of [(3)H]dihydroartemisinin translationally controlled tumor protein (TCTP) adducts from Plasmodium falciparum-infected erythrocytes by using anti-TCTP antibodies. Antimicrob. Agents Chemother. 45 (2001) 2397-2399
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2397-2399
    • Bhisutthibhan, J.1    Meshnick, S.R.2
  • 25
    • 0042860063 scopus 로고    scopus 로고
    • Artemisinins target the SERCA of Plasmodium falciparum
    • Eckstein-Ludwig U., et al. Artemisinins target the SERCA of Plasmodium falciparum. Nature 424 (2003) 957-961
    • (2003) Nature , vol.424 , pp. 957-961
    • Eckstein-Ludwig, U.1
  • 26
    • 20444365167 scopus 로고    scopus 로고
    • Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy
    • Efferth T. Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy. Drug Resist. Updat. 8 (2005) 85-97
    • (2005) Drug Resist. Updat. , vol.8 , pp. 85-97
    • Efferth, T.1
  • 27
    • 33646024956 scopus 로고    scopus 로고
    • Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
    • Efferth T. Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells. Curr. Drug Targets 7 (2006) 407-421
    • (2006) Curr. Drug Targets , vol.7 , pp. 407-421
    • Efferth, T.1
  • 28
    • 34250344275 scopus 로고    scopus 로고
    • Willmar schwabe award 2006: antiplasmodial and antitumor activity of artemisinin - from bench to bedside
    • Efferth T. Willmar schwabe award 2006: antiplasmodial and antitumor activity of artemisinin - from bench to bedside. Planta Med. 73 (2007) 299-309
    • (2007) Planta Med. , vol.73 , pp. 299-309
    • Efferth, T.1
  • 29
    • 0035315838 scopus 로고    scopus 로고
    • The anti-malarial artesunate is also active against cancer
    • Efferth T., et al. The anti-malarial artesunate is also active against cancer. Int. J. Oncol. 18 (2001) 767-773
    • (2001) Int. J. Oncol. , vol.18 , pp. 767-773
    • Efferth, T.1
  • 30
    • 0042844638 scopus 로고    scopus 로고
    • Molecular modes of action of artesunate in tumor cell lines
    • Efferth T., et al. Molecular modes of action of artesunate in tumor cell lines. Mol. Pharmacol. 64 (2003) 382-394
    • (2003) Mol. Pharmacol. , vol.64 , pp. 382-394
    • Efferth, T.1
  • 31
    • 33644672627 scopus 로고    scopus 로고
    • Artesunate in the treatment of metastatic uveal melanoma-first experiences
    • Berger T.G., et al. Artesunate in the treatment of metastatic uveal melanoma-first experiences. Oncol. Rep. 14 (2005) 1599-1603
    • (2005) Oncol. Rep. , vol.14 , pp. 1599-1603
    • Berger, T.G.1
  • 32
    • 17144377127 scopus 로고    scopus 로고
    • Arsenic trioxide: new clinical experience with an old medication in hematologic malignancies
    • Douer D., and Tallman M.S. Arsenic trioxide: new clinical experience with an old medication in hematologic malignancies. J. Clin. Oncol. 23 (2005) 2396-2410
    • (2005) J. Clin. Oncol. , vol.23 , pp. 2396-2410
    • Douer, D.1    Tallman, M.S.2
  • 34
    • 0017577805 scopus 로고
    • Inhibition of translation in eukaryotic systems by harringtonine
    • Fresno M., et al. Inhibition of translation in eukaryotic systems by harringtonine. Eur. J. Biochem. 72 (1977) 323-330
    • (1977) Eur. J. Biochem. , vol.72 , pp. 323-330
    • Fresno, M.1
  • 35
    • 0037280015 scopus 로고    scopus 로고
    • Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines
    • Efferth T., et al. Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines. Naunyn Schmiedebergs Arch. Pharmacol. 367 (2003) 56-67
    • (2003) Naunyn Schmiedebergs Arch. Pharmacol. , vol.367 , pp. 56-67
    • Efferth, T.1
  • 36
    • 0028920348 scopus 로고
    • MDR-related P170-glycoprotein modulates cytotoxic activity of homoharringtonine
    • Russo D., et al. MDR-related P170-glycoprotein modulates cytotoxic activity of homoharringtonine. Leukaemia 9 (1995) 513-516
    • (1995) Leukaemia , vol.9 , pp. 513-516
    • Russo, D.1
  • 37
    • 34547223314 scopus 로고    scopus 로고
    • Gillet, J.P. et al. Chemotherapy-induced resistance vy ATP-binding cassette transporter genes. Biochem. Biophys. Acta - Rev. Cancer (in press)
  • 38
    • 0035883408 scopus 로고    scopus 로고
    • Homoharringtonine: history, current research, and future direction
    • Kantarjian H.M., et al. Homoharringtonine: history, current research, and future direction. Cancer 92 (2001) 1591-1605
    • (2001) Cancer , vol.92 , pp. 1591-1605
    • Kantarjian, H.M.1
  • 39
    • 0037099645 scopus 로고    scopus 로고
    • Mechanisms of action of arsenic trioxide
    • Miller W.H., et al. Mechanisms of action of arsenic trioxide. Cancer Res. 62 (2002) 3893-3903
    • (2002) Cancer Res. , vol.62 , pp. 3893-3903
    • Miller, W.H.1
  • 40
    • 20444390332 scopus 로고    scopus 로고
    • Microarray-based prediction of cytotoxicity of tumor cells to arsenic trioxide
    • Efferth T., and Kaina B. Microarray-based prediction of cytotoxicity of tumor cells to arsenic trioxide. Cancer Genomics Proteomics 1 (2004) 363-370
    • (2004) Cancer Genomics Proteomics , vol.1 , pp. 363-370
    • Efferth, T.1    Kaina, B.2
  • 41
    • 33748442867 scopus 로고    scopus 로고
    • Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A
    • Shan H.B., et al. Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A. Anticancer Drugs 17 (2006) 905-911
    • (2006) Anticancer Drugs , vol.17 , pp. 905-911
    • Shan, H.B.1
  • 42
    • 13844267553 scopus 로고    scopus 로고
    • Molecular modes of action of cantharidin in tumor cells
    • Efferth T., et al. Molecular modes of action of cantharidin in tumor cells. Biochem. Pharmacol. 69 (2005) 811-818
    • (2005) Biochem. Pharmacol. , vol.69 , pp. 811-818
    • Efferth, T.1
  • 43
    • 0033578151 scopus 로고    scopus 로고
    • Review of randomised clinical controlled trials of traditional Chinese medicine
    • Tang J.L., et al. Review of randomised clinical controlled trials of traditional Chinese medicine. BMJ 319 (1999) 160-161
    • (1999) BMJ , vol.319 , pp. 160-161
    • Tang, J.L.1
  • 44
    • 33747614152 scopus 로고    scopus 로고
    • Research priorities in traditional Chinese medicine
    • Tang J.L. Research priorities in traditional Chinese medicine. BMJ 333 (2006) 391-394
    • (2006) BMJ , vol.333 , pp. 391-394
    • Tang, J.L.1
  • 45
    • 0027957893 scopus 로고
    • Highlight on the studies of anticancer drugs derived from plants in China
    • Han R. Highlight on the studies of anticancer drugs derived from plants in China. Stem Cells 12 (1994) 53-63
    • (1994) Stem Cells , vol.12 , pp. 53-63
    • Han, R.1
  • 46
    • 2142703918 scopus 로고    scopus 로고
    • Clinical studies of camptothecin and derivatives
    • Soepenberg O., et al. Clinical studies of camptothecin and derivatives. Alkaloids Chem. Biol. 60 (2003) 1-50
    • (2003) Alkaloids Chem. Biol. , vol.60 , pp. 1-50
    • Soepenberg, O.1
  • 48
    • 0030610687 scopus 로고    scopus 로고
    • 3) in the treatment of acute promyelocytic leukaemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients
    • 3) in the treatment of acute promyelocytic leukaemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 89 (1997) 3354-3360
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Z.X.1
  • 49
    • 0035884639 scopus 로고    scopus 로고
    • United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukaemia
    • Soignet S.L., et al. United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukaemia. J. Clin. Oncol. 19 (2001) 3852-3860
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3852-3860
    • Soignet, S.L.1
  • 50
    • 0023683186 scopus 로고
    • Cephalotaxine esters: antileukemic advance or therapeutic failure? J
    • Grem J.L., et al. Cephalotaxine esters: antileukemic advance or therapeutic failure? J. Natl. Cancer Inst. 80 (1988) 1095-1103
    • (1988) Natl. Cancer Inst. , vol.80 , pp. 1095-1103
    • Grem, J.L.1
  • 51
    • 5444238462 scopus 로고    scopus 로고
    • Homoharringtonine: a new treatment option for myeloid leukaemia
    • Luo C.Y., et al. Homoharringtonine: a new treatment option for myeloid leukaemia. Hematology 9 (2004) 259-270
    • (2004) Hematology , vol.9 , pp. 259-270
    • Luo, C.Y.1
  • 52
    • 0034622082 scopus 로고    scopus 로고
    • Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)
    • Nortier J.L., et al. Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). N. Engl. J. Med. 342 (2000) 1686-1692
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1686-1692
    • Nortier, J.L.1
  • 53
    • 0036020624 scopus 로고    scopus 로고
    • Aristolochic acid as a probable human cancer hazard in herbal remedies: a review
    • Arlt V.M., et al. Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. Mutagenesis 17 (2002) 265-277
    • (2002) Mutagenesis , vol.17 , pp. 265-277
    • Arlt, V.M.1
  • 54
    • 4143142193 scopus 로고    scopus 로고
    • Aristolochic acid (AA)-DNA adduct as marker of AA exposure and risk factor for AA nephropathy-associated cancer
    • Arlt V.M., et al. Aristolochic acid (AA)-DNA adduct as marker of AA exposure and risk factor for AA nephropathy-associated cancer. Int. J. Cancer 111 (2004) 977-980
    • (2004) Int. J. Cancer , vol.111 , pp. 977-980
    • Arlt, V.M.1
  • 55
    • 0025137138 scopus 로고
    • Medicine from plants
    • Abelson P.H. Medicine from plants. Science 247 (1990) 513
    • (1990) Science , vol.247 , pp. 513
    • Abelson, P.H.1
  • 56
    • 34547203354 scopus 로고    scopus 로고
    • Bioprospecting: the search for bioactive lead structures from nature
    • Kayser O., and Quax W.J. (Eds), Wiley-VCH
    • Wink M. Bioprospecting: the search for bioactive lead structures from nature. In: Kayser O., and Quax W.J. (Eds). Medical Plant Biotechnology: From Basic Research to Industrial Applications Vol. 2 (2007), Wiley-VCH 97-116
    • (2007) Medical Plant Biotechnology: From Basic Research to Industrial Applications , vol.2 , pp. 97-116
    • Wink, M.1
  • 60
    • 0021910220 scopus 로고
    • Homoharringtonine: an effective new drug for remission induction in refractory nonlymphoblastic leukaemia
    • Warrell Jr. R.P., et al. Homoharringtonine: an effective new drug for remission induction in refractory nonlymphoblastic leukaemia. J. Clin. Oncol. 3 (1985) 617-621
    • (1985) J. Clin. Oncol. , vol.3 , pp. 617-621
    • Warrell Jr., R.P.1
  • 61
    • 0023461335 scopus 로고
    • Phase I trial of homoharringtonine in children with refractory leukaemia
    • Tan C.T., et al. Phase I trial of homoharringtonine in children with refractory leukaemia. Cancer Treat. Rep. 71 (1987) 1245-1248
    • (1987) Cancer Treat. Rep. , vol.71 , pp. 1245-1248
    • Tan, C.T.1
  • 62
    • 0026499322 scopus 로고    scopus 로고
    • Feldman, E. et al. (1992a) Homoharringtonine is safe and effective for patients with acute myelogenous leukaemia. Leukaemia 6, 1185-1188
  • 63
    • 0026499681 scopus 로고    scopus 로고
    • Feldman, E. et al. (1992b) Homoharringtonine in combination with cytarabine for patients with acute myelogenous leukaemia. Leukaemia 6, 1189-1191
  • 64
    • 0034910943 scopus 로고    scopus 로고
    • A phase II study of Homoharringtonine for the treatment of children with refractory or recurrent acute myelogenous leukaemia: a pediatric oncology group study
    • Bell B.A., et al. A phase II study of Homoharringtonine for the treatment of children with refractory or recurrent acute myelogenous leukaemia: a pediatric oncology group study. Med. Pediatr. Oncol. 37 (2001) 103-107
    • (2001) Med. Pediatr. Oncol. , vol.37 , pp. 103-107
    • Bell, B.A.1
  • 65
    • 33746883844 scopus 로고    scopus 로고
    • A phase I dose-finding and pharmacokinetic study of subcutaneous semisynthetic homoharringtonine (ssHHT) in patients with advanced acute myeloid leukaemia
    • Levy V., et al. A phase I dose-finding and pharmacokinetic study of subcutaneous semisynthetic homoharringtonine (ssHHT) in patients with advanced acute myeloid leukaemia. Br. J. Cancer 95 (2006) 253-259
    • (2006) Br. J. Cancer , vol.95 , pp. 253-259
    • Levy, V.1
  • 66
    • 33746105303 scopus 로고    scopus 로고
    • Homoharringtonine in combination with cytarabine and aclarubicin resulted in high complete remission rate after the first induction therapy in patients with de novo acute myeloid leukaemia
    • Jin J., et al. Homoharringtonine in combination with cytarabine and aclarubicin resulted in high complete remission rate after the first induction therapy in patients with de novo acute myeloid leukaemia. Leukaemia 20 (2006) 1361-1367
    • (2006) Leukaemia , vol.20 , pp. 1361-1367
    • Jin, J.1
  • 67
    • 0030051722 scopus 로고    scopus 로고
    • Homoharringtonine in patients with myelodysplastic syndrome (MDS) and MDS evolving to acute myeloid leukaemia
    • Feldman E.J., et al. Homoharringtonine in patients with myelodysplastic syndrome (MDS) and MDS evolving to acute myeloid leukaemia. Leukaemia 10 (1996) 40-42
    • (1996) Leukaemia , vol.10 , pp. 40-42
    • Feldman, E.J.1
  • 68
    • 0034667856 scopus 로고    scopus 로고
    • Kantarjian, H.M. et al. (2000b) Homoharringtonine and low-dose cytarabine in the management of late chronic-phase chronic myelogenous leukaemia. J. Clin. Oncol. 18, 3513-3521
  • 69
    • 0041887168 scopus 로고    scopus 로고
    • Results of triple therapy with interferon-alpha, cytarabine, and homoharringtonine, and the impact of adding imatinib to the treatment sequence in patients with Philadelphia chromosome-positive chronic myelogenous leukaemia in early chronic phase
    • O'Brien S., et al. Results of triple therapy with interferon-alpha, cytarabine, and homoharringtonine, and the impact of adding imatinib to the treatment sequence in patients with Philadelphia chromosome-positive chronic myelogenous leukaemia in early chronic phase. Cancer 98 (2003) 888-893
    • (2003) Cancer , vol.98 , pp. 888-893
    • O'Brien, S.1
  • 70
    • 17644395643 scopus 로고    scopus 로고
    • Phase I/II trial of adding semisynthetic homoharringtonine in chronic myeloid leukaemia patients who have achieved partial or complete cytogenetic response on imatinib
    • Marin D., et al. Phase I/II trial of adding semisynthetic homoharringtonine in chronic myeloid leukaemia patients who have achieved partial or complete cytogenetic response on imatinib. Cancer 103 (2005) 1850-1855
    • (2005) Cancer , vol.103 , pp. 1850-1855
    • Marin, D.1
  • 71
    • 0021646813 scopus 로고
    • Intermittent Iv homoharringtonine for the treatment of refractory epithelial carcinoma of the ovary: a phase II trial
    • Kavanagh J.J., et al. Intermittent Iv homoharringtonine for the treatment of refractory epithelial carcinoma of the ovary: a phase II trial. Cancer Treat. Rep. 68 (1984) 1503-1504
    • (1984) Cancer Treat. Rep. , vol.68 , pp. 1503-1504
    • Kavanagh, J.J.1
  • 72
    • 0022993697 scopus 로고
    • A clinical trial of homoharringtonine in the treatment of advanced breast cancer
    • Zhao T.P., et al. A clinical trial of homoharringtonine in the treatment of advanced breast cancer. Tumori 72 (1986) 395-398
    • (1986) Tumori , vol.72 , pp. 395-398
    • Zhao, T.P.1
  • 73
    • 0022572796 scopus 로고
    • Phase II studies of homoharringtonine in patients with advanced malignant melanoma; sarcoma; and head and neck, breast, and colorectal carcinomas
    • Ajani J.A., et al. Phase II studies of homoharringtonine in patients with advanced malignant melanoma; sarcoma; and head and neck, breast, and colorectal carcinomas. Cancer Treat. Rep. 70 (1986) 375-379
    • (1986) Cancer Treat. Rep. , vol.70 , pp. 375-379
    • Ajani, J.A.1
  • 74
    • 0024322252 scopus 로고
    • Evaluation of homoharringtonine efficacy in the treatment of squamous cell carcinoma of the head and neck: a phase II Illinois Cancer Council Study
    • Runge-Morris M.A., et al. Evaluation of homoharringtonine efficacy in the treatment of squamous cell carcinoma of the head and neck: a phase II Illinois Cancer Council Study. Invest. New Drugs 7 (1989) 269-273
    • (1989) Invest. New Drugs , vol.7 , pp. 269-273
    • Runge-Morris, M.A.1
  • 75
    • 0025071889 scopus 로고
    • Phase II study of homoharringtonine in patients with recurrent primary malignant central nervous system tumors
    • Feun L.G., et al. Phase II study of homoharringtonine in patients with recurrent primary malignant central nervous system tumors. J. Neurooncol. 9 (1990) 159-163
    • (1990) J. Neurooncol. , vol.9 , pp. 159-163
    • Feun, L.G.1
  • 76
    • 0030465768 scopus 로고    scopus 로고
    • A phase II trial of amonafide, caracemide, and homoharringtonine in the treatment of patients with advanced renal cell cancer
    • Witte R.S., et al. A phase II trial of amonafide, caracemide, and homoharringtonine in the treatment of patients with advanced renal cell cancer. Invest. New Drugs 14 (1996) 409-413
    • (1996) Invest. New Drugs , vol.14 , pp. 409-413
    • Witte, R.S.1
  • 77
    • 0032762487 scopus 로고    scopus 로고
    • A phase II trial of homoharringtonine and caracemide in the treatment of patients with advanced large bowel cancer
    • Witte R.S., et al. A phase II trial of homoharringtonine and caracemide in the treatment of patients with advanced large bowel cancer. Invest. New Drugs 17 (1999) 173-177
    • (1999) Invest. New Drugs , vol.17 , pp. 173-177
    • Witte, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.