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Volumn 79, Issue 4, 2010, Pages 288-295

Genetic polymorphisms of the serotonin transporter, but not the 2a receptor or nitric oxide synthetase, are associated with pulmonary hypertension in chronic obstructive pulmonary disease

Author keywords

Chronic obstructive pulmonary disease; Genetic; Polymorphism; Pulmonary hypertension; Serotonin; Serotonin transporter

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER;

EID: 77949272806     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000226243     Document Type: Article
Times cited : (39)

References (40)
  • 1
    • 0038056173 scopus 로고    scopus 로고
    • Pulmonary hypertension in chronic obstructive pulmonary disease
    • Barbera JA, Peinado VI, Santos S: Pulmonary hypertension in chronic obstructive pulmonary disease. Eur Respir J 2003;21:892-905.
    • (2003) Eur Respir J , vol.21 , pp. 892-905
    • Barbera, J.A.1    Peinado, V.I.2    Santos, S.3
  • 6
    • 19844371035 scopus 로고    scopus 로고
    • Severe pulmonary hypertension in COPD: Is it a distinct disease?
    • Weitzenblum E, Chaouat A: Severe pulmonary hypertension in COPD: is it a distinct disease? Chest 2005;127:1480-1482.
    • (2005) Chest , vol.127 , pp. 1480-1482
    • Weitzenblum, E.1    Chaouat, A.2
  • 9
    • 0035033623 scopus 로고    scopus 로고
    • Association study of the 5-HT(2A) receptor gene polymorphism, T102C and essential hypertension
    • Liolitsa D, Powell JF, Prince M, Lovestone S: Association study of the 5-HT(2A) receptor gene polymorphism, T102C and essential hypertension. J Hum Hypertens 2001;15:335-339.
    • (2001) J Hum Hypertens , vol.15 , pp. 335-339
    • Liolitsa, D.1    Powell, J.F.2    Prince, M.3    Lovestone, S.4
  • 10
    • 0034181950 scopus 로고    scopus 로고
    • T102C polymorphism of the serotonin (5-HT) 2A receptor gene in patients with non-fatal acute myocardial infarction
    • Yamada S, Akita H, Kanazawa K, Ishida T, Hirata K, Ito K, Kawashima S, Yokoyama M: T102C polymorphism of the serotonin (5-HT) 2A receptor gene in patients with non-fatal acute myocardial infarction. Atherosclerosis 2000;150:143-148.
    • (2000) Atherosclerosis , vol.150 , pp. 143-148
    • Yamada, S.1    Akita, H.2    Kanazawa, K.3    Ishida, T.4    Hirata, K.5    Ito, K.6    Kawashima, S.7    Yokoyama, M.8
  • 12
    • 0037072457 scopus 로고    scopus 로고
    • Positive association of the endothelial nitric oxide synthase gene polymorphisms with high-altitude pulmonary edema
    • Droma Y, Hanaoka M, Ota M, Katsuyama Y, Koizumi T, Fujimoto K, Kobayashi T, Kubo K: Positive association of the endothelial nitric oxide synthase gene polymorphisms with high-altitude pulmonary edema. Circulation 2002;106:826-830.
    • (2002) Circulation , vol.106 , pp. 826-830
    • Droma, Y.1    Hanaoka, M.2    Ota, M.3    Katsuyama, Y.4    Koizumi, T.5    Fujimoto, K.6    Kobayashi, T.7    Kubo, K.8
  • 13
    • 33751236205 scopus 로고    scopus 로고
    • Heterozygotes of NOS3 polymorphisms contribute to reduced nitrogen oxides in high-altitude pulmonary edema
    • Ahsan A, Mohd G, Norboo T, Baig MA, Pasha MA: Heterozygotes of NOS3 polymorphisms contribute to reduced nitrogen oxides in high-altitude pulmonary edema. Chest 2006;130:1511-1519.
    • (2006) Chest , vol.130 , pp. 1511-1519
    • Ahsan, A.1    Mohd, G.2    Norboo, T.3    Baig, M.A.4    Pasha, M.A.5
  • 14
    • 33846524379 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase polymorphisms do not influence pulmonary artery systolic pressure at altitude
    • Smith EM, Baillie JK, Thompson AA, Irving JB, Porteous D, Webb DJ: Endothelial nitric oxide synthase polymorphisms do not influence pulmonary artery systolic pressure at altitude. High Alt Med Biol 2006;7:221-227.
    • (2006) High Alt Med Biol , vol.7 , pp. 221-227
    • Smith, E.M.1    Baillie, J.K.2    Thompson, A.A.3    Irving, J.B.4    Porteous, D.5    Webb, D.J.6
  • 15
    • 0028827084 scopus 로고    scopus 로고
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. American Thoracic Society. Am J Respir Crit Care Med 1995;152:S77-S121.
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. American Thoracic Society. Am J Respir Crit Care Med 1995;152:S77-S121.
  • 16
    • 13044268007 scopus 로고    scopus 로고
    • The COPD Guidelines Group of the Standards of Care Committee of the BTS
    • BTS guidelines for the management of chronic obstructive pulmonary disease
    • BTS guidelines for the management of chronic obstructive pulmonary disease. The COPD Guidelines Group of the Standards of Care Committee of the BTS. Thorax 1997;52(suppl 5):S1-S28.
    • (1997) Thorax , vol.52 , Issue.SUPPL. 5
  • 18
    • 19844369633 scopus 로고    scopus 로고
    • Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation
    • Thabut G, Dauriat G, Stern JB, Logeart D, Levy A, Marrash-Chahla R, Mal H: Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation. Chest 2005;127:1531-1536.
    • (2005) Chest , vol.127 , pp. 1531-1536
    • Thabut, G.1    Dauriat, G.2    Stern, J.B.3    Logeart, D.4    Levy, A.5    Marrash-Chahla, R.6    Mal, H.7
  • 21
    • 26844473397 scopus 로고    scopus 로고
    • The Asp298 but not the C-786 genotype of the endothelial nitric oxide synthase is reduced with age in healthy Swiss men
    • Muntwyler J, Marti-Jaun J, Luscher TF, Hanseler E, Hersberger M: The Asp298 but not the C-786 genotype of the endothelial nitric oxide synthase is reduced with age in healthy Swiss men. Clin Chem Lab Med 2005;43:971-973.
    • (2005) Clin Chem Lab Med , vol.43 , pp. 971-973
    • Muntwyler, J.1    Marti-Jaun, J.2    Luscher, T.F.3    Hanseler, E.4    Hersberger, M.5
  • 22
    • 0030048029 scopus 로고    scopus 로고
    • A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene
    • Wang XL, Sim AS, Badenhop RF, McCredie RM, Wilcken DE: A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat Med 1996;2:41-45.
    • (1996) Nat Med , vol.2 , pp. 41-45
    • Wang, X.L.1    Sim, A.S.2    Badenhop, R.F.3    McCredie, R.M.4    Wilcken, D.E.5
  • 23
    • 2942661490 scopus 로고    scopus 로고
    • Detection of the Arg702Trp, Gly908Arg and Leu1007fsinsC polymorphisms of the NOD2/CARD15 gene by real-time PCR with melting curve analysis
    • Ruegg C, Hersberger M, Wusk B, Rentsch K, Kullak-Ublick GA, von Eckardstein A, Maly FE: Detection of the Arg702Trp, Gly908Arg and Leu1007fsinsC polymorphisms of the NOD2/CARD15 gene by real-time PCR with melting curve analysis. Clin Chem Lab Med 2004;42:494-498.
    • (2004) Clin Chem Lab Med , vol.42 , pp. 494-498
    • Ruegg, C.1    Hersberger, M.2    Wusk, B.3    Rentsch, K.4    Kullak-Ublick, G.A.5    von Eckardstein, A.6    Maly, F.E.7
  • 24
    • 56649123063 scopus 로고    scopus 로고
    • Assessment of patients with pulmonary hypertension
    • McNeil K: Assessment of patients with pulmonary hypertension. Respiration 2008;76:373-374.
    • (2008) Respiration , vol.76 , pp. 373-374
    • McNeil, K.1
  • 25
    • 0036844311 scopus 로고    scopus 로고
    • Pulmonary hypertension in scleroderma spectrum of disease: Lack of bone morphogenetic protein receptor 2 mutations
    • Morse J, Barst R, Horn E, Cuervo N, Deng Z, Knowles J: Pulmonary hypertension in scleroderma spectrum of disease: lack of bone morphogenetic protein receptor 2 mutations. J Rheumatol 2002;29:2379-2381.
    • (2002) J Rheumatol , vol.29 , pp. 2379-2381
    • Morse, J.1    Barst, R.2    Horn, E.3    Cuervo, N.4    Deng, Z.5    Knowles, J.6
  • 26
    • 0037266518 scopus 로고    scopus 로고
    • Genetic studies of pulmonary arterialhy per tension
    • Morse JH: Genetic studies of pulmonary arterialhy per tension. Lupus 2003;12:209-212.
    • (2003) Lupus , vol.12 , pp. 209-212
    • Morse, J.H.1
  • 27
    • 0034096980 scopus 로고    scopus 로고
    • Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
    • Eddahibi S, Hanoun N, Lanfumey L, Lesch KP, Raffestin B, Hamon M, Adnot S: Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J Clin Invest 2000;105:1555-1562.
    • (2000) J Clin Invest , vol.105 , pp. 1555-1562
    • Eddahibi, S.1    Hanoun, N.2    Lanfumey, L.3    Lesch, K.P.4    Raffestin, B.5    Hamon, M.6    Adnot, S.7
  • 28
    • 17444448272 scopus 로고    scopus 로고
    • Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension
    • Eddahibi S, Humbert M, Fadel E, Raffestin B, Darmon M, Capron F, Simonneau G, Dartevelle P, Hamon M, Adnot S: Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension. Chest 2002;121:97S-98S.
    • (2002) Chest , vol.121
    • Eddahibi, S.1    Humbert, M.2    Fadel, E.3    Raffestin, B.4    Darmon, M.5    Capron, F.6    Simonneau, G.7    Dartevelle, P.8    Hamon, M.9    Adnot, S.10
  • 31
    • 30144436344 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism in a cohort of German patients with idiopathic pulmonary arterial hypertension or chronic thromboembolic pulmonary hyper tension
    • Koehler R, Olschewski H, Hoeper M, Janssen B, Grunig E: Serotonin transporter gene polymorphism in a cohort of German patients with idiopathic pulmonary arterial hypertension or chronic thromboembolic pulmonary hyper tension. Chest 2005;128:619S.
    • (2005) Chest , vol.128
    • Koehler, R.1    Olschewski, H.2    Hoeper, M.3    Janssen, B.4    Grunig, E.5
  • 33
    • 25444451561 scopus 로고    scopus 로고
    • Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: Lessons for the future in pathogenesis
    • Eddahibi S, Adnot S: Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: lessons for the future in pathogenesis. Respir Res 2002;3:9.
    • (2002) Respir Res , vol.3 , pp. 9
    • Eddahibi, S.1    Adnot, S.2
  • 34
    • 16644398461 scopus 로고    scopus 로고
    • The serotonin receptor and transporter as potential therapeutic targets for pulmonary hypertension
    • Wang HL: The serotonin receptor and transporter as potential therapeutic targets for pulmonary hypertension. Curr Opin Investig Drugs 2004;5:963-966.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 963-966
    • Wang, H.L.1
  • 37
    • 41349089311 scopus 로고    scopus 로고
    • Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hyper tension
    • Ulrich S, Nicolls MR, Taraseviciene L, Speich R, Voelkel N: Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hyper tension. Respiration 2008;75:272-280.
    • (2008) Respiration , vol.75 , pp. 272-280
    • Ulrich, S.1    Nicolls, M.R.2    Taraseviciene, L.3    Speich, R.4    Voelkel, N.5
  • 38
    • 0021827224 scopus 로고
    • Long-term oxygen therapy can reverse the progression of pulmonary hypertension in patients with chronic obstructive pulmonary disease
    • Weitzenblum E, Sautegeau A, Ehrhart M, Mammosser M, Pelletier A: Long-term oxygen therapy can reverse the progression of pulmonary hypertension in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1985;131:493-498.
    • (1985) Am Rev Respir Dis , vol.131 , pp. 493-498
    • Weitzenblum, E.1    Sautegeau, A.2    Ehrhart, M.3    Mammosser, M.4    Pelletier, A.5
  • 39
    • 0031888040 scopus 로고    scopus 로고
    • Right and left ventricular dysfunction in patients with severe pulmonary disease
    • Vizza CD, Lynch JP, Ochoa LL, Richardson G, Trulock EP: Right and left ventricular dysfunction in patients with severe pulmonary disease. Chest 1998;113:576-583.
    • (1998) Chest , vol.113 , pp. 576-583
    • Vizza, C.D.1    Lynch, J.P.2    Ochoa, L.L.3    Richardson, G.4    Trulock, E.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.