Microtubule disruption inhibits autophagosome-lysosome fusion: Implications for studying the roles of aggresomes in polyglutamine diseases

International Journal of Biochemistry and Cell Biology

Volumn 36, Issue 12, 2004, Pages 2541-2550

  Webb, Julie L ^a   Ravikumar, Brinda ^a   Rubinsztein, David C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Aggresomes; Alpha synuclein; Autophagy; Huntington's disease; Nocodazole; Polyglutamine diseases

Indexed keywords

ALANINE; GLUTAMINE; HUNTINGTIN; NOCODAZOLE; POLYGLUTAMINE;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; CELL NUCLEUS; CELL STRAIN; CONTROLLED STUDY; DRUG EFFECT; EXON; INHIBITION KINETICS; LYSOSOME; MICROTUBULE; MUTANT; NONHUMAN; PHAGOSOME; PROTEIN EXPRESSION; RAT;

ANIMALS; AUTOPHAGY; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; HUNTINGTON DISEASE; INCLUSION BODIES; LYSOSOMES; MEMBRANE FUSION; MICROTUBULES; NEURODEGENERATIVE DISEASES; NOCODAZOLE; ORGANISMS, GENETICALLY MODIFIED; PARKINSON DISEASE; PC12 CELLS; PEPTIDES; RATS;

EID: 4344622423     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2004.02.003     Document Type: Article

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