-
1
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
DOI 10.1093/hmg/ddi379
-
Yamazaki, K., McGovern, D., Ragoussis, J., Paolucci, M., Butler, H., Jewell, D. et al. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum. Mol. Genet. 14, 3499-3506 (2005). (Pubitemid 41672132)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.22
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
Paolucci, M.4
Butler, H.5
Jewell, D.6
Cardon, L.7
Takazoe, M.8
Tanaka, T.9
Ichimori, T.10
Saito, S.11
Sekine, A.12
Iida, A.13
Takahashi, A.14
Tsunoda, T.15
Lathrop, M.16
Nakamura, Y.17
-
2
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
DOI 10.1126/science.1135245
-
Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J. et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science314, 1461-1463 (2006). (Pubitemid 44871953)
-
(2006)
Science
, vol.314
, Issue.5804
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
3
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
DOI 10.1038/ng1954, PII NG1954
-
Hampe, J., Franke, A., Rosenstiel, P., Till, A., Teuber, M., Huse, K. et al. Agenome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 39, 207-211 (2007). (Pubitemid 46184351)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
4
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
DOI 10.1038/ng2032, PII NG2032
-
Rioux, J. D., Xavier, R. J., Taylor, K. D., Silverberg, M. S., Goyette, P., Huett, A. et al. Genome-wide association study identifies new susceptibility loci for Crohn's disease and implicates autophage in disease pathogenesis. Nat Genet. 39, 596-604 (2007). (Pubitemid 46676115)
-
(2007)
Nature Genetics
, vol.39
, Issue.5
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
Green, T.7
Kuballa, P.8
Barmada, M.M.9
Datta, L.W.10
Shugart, Y.Y.11
Griffiths, A.M.12
Targan, S.R.13
Ippoliti, A.F.14
Bernard, E.-J.15
Mei, L.16
Nicolae, D.L.17
Regueiro, M.18
Schumm, L.P.19
Steinhart, A.H.20
Rotter, J.I.21
Duerr, R.H.22
Cho, J.H.23
Daly, M.J.24
Brant, S.R.25
more..
-
5
-
-
84969213492
-
Genome-wide association study of 14000 cases of seven common diseases and 3000 shared controls
-
The Wellcome Trust Case Control Consortium
-
The Wellcome Trust Case Control Consortium. Genome-wide association study of 14000 cases of seven common diseases and 3000 shared controls. Nature 447, 661-678 (2007).
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
6
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett, J. C., Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D. et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 40, 955-962 (2008).
-
(2008)
Nat Genet.
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
-
7
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
DOI 10.1038/ng.145, PII NG145
-
Fisher, S. A., Tremelling, M., Anderson, C. A., Gwilliam, R., Bumpstead, S., Prescott, N. J. et al. Genetic determinants of ulcerativecolitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet. 40, 710-712 (2008). (Pubitemid 351748865)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 710-712
-
-
Fisher, S.A.1
Tremelling, M.2
Anderson, C.A.3
Gwilliam, R.4
Bumpstead, S.5
Prescott, N.J.6
Nimmo, E.R.7
Massey, D.8
Berzuini, C.9
Johnson, C.10
Barrett, J.C.11
Cummings, F.R.12
Drummond, H.13
Lees, C.W.14
Onnie, C.M.15
Hanson, C.E.16
Blaszczyk, K.17
Inouye, M.18
Ewels, P.19
Ravindrarajah, R.20
Keniry, A.21
Hunt, S.22
Carter, M.23
Watkins, N.24
Ouwehand, W.25
Lewis, C.M.26
Cardon, L.27
Lobo, A.28
Forbes, A.29
Sanderson, J.30
Jewell, D.P.31
Mansfield, J.C.32
Deloukas, P.33
Mathew, C.G.34
Parkes, M.35
Satsangi, J.36
more..
-
8
-
-
55049111426
-
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke, A., Balschun, T., Karlsen, T. H., Sventoraityte, J., Nikolaus, S., Mayr, G. et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility Nat Genet. 40, 1319-1323 (2008).
-
(2008)
Nat Genet.
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
Mayr, G.6
-
9
-
-
59149087627
-
Ulcerative colitis-risk loci on chromosome 1p36 and 12q15 found by genome-wide association study
-
Silverberg, M. S., Cho, J. H., Rioux, J. D., McGovern, D. P., Wu, J., Annese, V. et al. Ulcerative colitis-risk loci on chromosome 1p36 and 12q15 found by genome-wide association study. Nat Genet. 41, 216-220 (2009).
-
(2009)
Nat Genet.
, vol.41
, pp. 216-220
-
-
Silverberg, M.S.1
Cho, J.H.2
Rioux, J.D.3
McGovern, D.P.4
Wu, J.5
Annese, V.6
-
10
-
-
70649086082
-
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in theJapanese population
-
Asano, K., Matsushita, T., Umeno, J., Hosono, N., Takahashi, A., Kawaguchi, T. et al. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in theJapanese population. Nat Genet. 41, 1325-1329 (2009).
-
(2009)
Nat Genet.
, vol.41
, pp. 1325-1329
-
-
Asano, K.1
Matsushita, T.2
Umeno, J.3
Hosono, N.4
Takahashi, A.5
Kawaguchi, T.6
-
11
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
DOI 10.1038/ng.148, PII NG148
-
Franke, A., Balschun, T., Karlsen, T. H., Hedderich, J., May, S., Lu, T. et al. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet. 40, 713-715 (2008). (Pubitemid 351748866)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Hedderich, J.4
May, S.5
Lu, T.6
Schuldt, D.7
Nikolaus, S.8
Rosenstiel, P.9
Krawczak, M.10
Schreiber, S.11
-
12
-
-
58949097704
-
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
-
Anderson, C. A., Massey, D. C., Barrett, J. C., Prescott, N. J., Tremelling, M., Fisher, S. A. et al. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology 136, 523-529 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 523-529
-
-
Anderson, C.A.1
Massey, D.C.2
Barrett, J.C.3
Prescott, N.J.4
Tremelling, M.5
Fisher, S.A.6
-
13
-
-
0035941220
-
CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways
-
Bouchier-Hayes, L., Conroy, H., Egan, H., Adrain, C., Creagh, E. M., MacFarlane, M. et al. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways. J. Biol. Chem. 276, 44069-44077 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44069-44077
-
-
Bouchier-Hayes, L.1
Conroy, H.2
Egan, H.3
Adrain, C.4
Creagh, E.M.5
MacFarlane, M.6
-
14
-
-
0037134457
-
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
-
DOI 10.1074/jbc.M107811200
-
Razmara, M., Srinivasula, S. M., Wang, L., Poyet, J. L., Geddes, B. J., DiStefano, P. S. et al. CARD-8 protein, a newCARD family member that regulates caspase-1 activation and apoptosis. J. Biol. Chem. 277, 13952-13958 (2002). (Pubitemid 34968002)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 13952-13958
-
-
Razmara, M.1
Srinivasula, S.M.2
Wang, L.3
Poyet, J.-L.4
Geddes, B.J.5
Distefano, P.S.6
Bertin, J.7
Alnemri, E.S.8
-
15
-
-
0035943736
-
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein over-expressed in cancer
-
Pathan, N., Marusawa, H., Krajewska, M., Matsuzawa, S., Kim, H., Okada, K. et al. TUCAN, an antiapoptotic caspase-associated recruitment domain family protein over-expressed in cancer. J. Biol. Chem. 276, 32220-32229 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32220-32229
-
-
Pathan, N.1
Marusawa, H.2
Krajewska, M.3
Matsuzawa, S.4
Kim, H.5
Okada, K.6
-
16
-
-
25444522597
-
A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis
-
DOI 10.1158/0008-5472.CAN-04-4649
-
Yamamoto, M., Torigoe, T., Kamiguchi, K., Hirohashi, Y., Nakanishi, K., Nabeta, C. et al. A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8-and caspase-9-mediated apoptosis. Cancer. Res. 65, 8706-8714 (2005). (Pubitemid 41377358)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 8706-8714
-
-
Yamamoto, M.1
Torigoe, T.2
Kamiguchi, K.3
Hirohashi, Y.4
Nakanishi, K.5
Nabeta, C.6
Asanuma, H.7
Tsuruma, T.8
Sato, T.9
Hata, F.10
Ohmura, T.11
Yamaguchi, K.12
Kurotaki, T.13
Hirata, K.14
Sato, N.15
-
17
-
-
34347382756
-
MDP-induced interleukin-1β processing requires Nod2 and CIAS1/NALP3
-
DOI 10.1189/jlb.1006627
-
Pan, Q., Mathison, J., Fearns, C., Kravchenko, V. V., Da Silva Correia, J., Hoffman, H. M. et al. MDP-induced interleukin-1beta processing requires Nod2 and CIASI/NALP3. J. Leukoc. Biol. 82, 177-183 (2007). (Pubitemid 47026429)
-
(2007)
Journal of Leukocyte Biology
, vol.82
, Issue.1
, pp. 177-183
-
-
Pan, Q.1
Mathison, J.2
Fearns, C.3
Kravchenko, V.V.4
Correia, J.D.S.5
Hoffman, H.M.6
Kobayashi, K.S.7
Bertin, J.8
Grant, E.P.9
Coyle, A.J.10
Sutterwala, F.S.11
Ogura, Y.12
Flavell, R.A.13
Ulevitch, R.J.14
-
18
-
-
77953733399
-
The caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling
-
von Kampen, O., Lipinski, S., Till, A., Martin, S. J., Nietfeld, W., Lehrach, H. et al. The caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling. J. Biol. Chem. 285, 19921-19926 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19921-19926
-
-
Von Kampen, O.1
Lipinski, S.2
Till, A.3
Martin, S.J.4
Nietfeld, W.5
Lehrach, H.6
-
19
-
-
0036886298
-
Thecurrent future understandingof inflammatory bowel disease
-
Podolsky, D. K. Thecurrent future understandingof inflammatory bowel disease. Best. Pract. Res. Clin. Gastroenterol. 16, 933-943 (2002).
-
(2002)
Best. Pract. Res. Clin. Gastroenterol.
, vol.16
, pp. 933-943
-
-
Podolsky, D.K.1
-
20
-
-
0036671894
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
DOI 10.1016/S1097-2765(02)00599-3
-
Martinon, F., Burns, K. & Tschopp, J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-1β. Mol. Cell 10, 417-426 (2002). (Pubitemid 35007355)
-
(2002)
Molecular Cell
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
21
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/Cryopyrin inflammasome
-
DOI 10.1016/j.cub.2004.10.027, PII S0960982204008309
-
Martinon, F., Agostini, L., Meylan, E., Tschopp, J. et al. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14, 1929-1934 (2004). (Pubitemid 39464816)
-
(2004)
Current Biology
, vol.14
, Issue.21
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
22
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
-
Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N. & Tschopp, J. NALP3 forms an IL-1beta processing inflammasomewith increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319-325 (2004). (Pubitemid 38388233)
-
(2004)
Immunity
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
23
-
-
45549093755
-
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide
-
DOI 10.1073/pnas.0802726105
-
Hsu, L. C., Ali, S. R., McGillivray S., Tseng, P. H., Mariathasan, S., Humke, E. W. et al. A-NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc. Natl. Acad. Sci. USA. 105, 7803-7808 (2008). (Pubitemid 351872719)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.22
, pp. 7803-7808
-
-
Hsu, L.-C.1
Ali, S.R.2
McGillivray, S.3
Tseng, P.-H.4
Mariathasan, S.5
Humke, E.W.6
Eckmann, L.7
Powell, J.J.8
Nizet, V.9
Dixit, V.M.10
Karin, M.11
-
24
-
-
38349081519
-
Engagement of NOD2 has a dual effect on proIL-1β mRNA transcription and secretion of bioactive IL-1β
-
Ferwerda, G., Kramer, M., deJong, D., Piccini, A., Joosten, L. A., Devesaginer, I. et al. Engagement of NOD2 has a dual effect on proIL-1β mRNA transcription and secretion of bioactive IL-1β. Eur. J. Immunol. 38, 184-191 (2008).
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 184-191
-
-
Ferwerda, G.1
Kramer, M.2
Dejong, D.3
Piccini, A.4
Joosten, L.A.5
Devesaginer, I.6
-
25
-
-
33749465291
-
TUCAN (CARD8) Genetic Variants and Inflammatory Bowel Disease
-
DOI 10.1053/j.gastro.2006.08.008, PII S0016508506017252
-
McGovern, D. P., Butler, H., Ahmad, T., Paolucci, M., van Heel, D. A., Negoro, K. et al. Tucan (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology 131, 1190-1196 (2006). (Pubitemid 44515100)
-
(2006)
Gastroenterology
, vol.131
, Issue.4
, pp. 1190-1196
-
-
McGovern, D.P.B.1
Butler, H.2
Ahmad, T.3
Paolucci, M.4
Van Heel, D.A.5
Negoro, K.6
Hysi, P.7
Ragoussis, J.8
Travis, S.P.L.9
Cardon, L.R.10
Jewell, D.P.11
-
26
-
-
34247609785
-
Combined Evidence From Three Large British Association Studies Rejects TUCAN/CARD8 as an IBD Susceptibility Gene
-
DOI 10.1053/j.gastro.2007.03.086, PII S0016508507006129
-
Fisher, S. A., Mirza, M. M., Onnie, C. M., Soars, D., Lewis, C. M., Prescott, N. J. et al. Combined evidence from three large British Association studies rejects TUCAN/CARD8 as an IBD susceptibility gene. Gastroenterology 132, 2078-2080 (2007). (Pubitemid 46677970)
-
(2007)
Gastroenterology
, vol.132
, Issue.5
, pp. 2078-2080
-
-
Fisher, S.A.1
Mirza, M.M.2
Onnie, C.M.3
Soars, D.4
Lewis, C.M.5
Prescott, N.J.6
Mathew, C.G.7
Sanderson, J.8
Forbes, A.9
Todhunter, C.10
Donaldson, P.11
Mansfield, J.12
-
27
-
-
34247600572
-
No Association Between the TUCAN (CARD8) Cys10Stop Mutation and Inflammatory Bowel Disease in a Large Retrospective German and a Clinically Well-Characterized Norwegian Sample
-
DOI 10.1053/j.gastro.2007.03.087, PII S0016508507006130
-
Franke, A., Rosenstiel, P., Balschun, T., Von Kampen, O., Schreiber, S., Sina, C. et al. No association between the TUCAN (CARD8) Cys10Stop mutation and inflammatory bowel disease in a large retrospective German and a clinically well-characterized Norwegian sample. Gastroenterology132, 2080-2081 (2007). (Pubitemid 46677971)
-
(2007)
Gastroenterology
, vol.132
, Issue.5
, pp. 2080-2081
-
-
Franke, A.1
Rosenstiel, P.2
Balschun, T.3
Von Kampen, O.4
Schreiber, S.5
Sina, C.6
Hampe, J.7
Karlsen, T.H.8
Vatn, M.H.9
Solberg, C.10
-
28
-
-
41149132262
-
No association of the CARD8 (TUCAN) c. 30T>A (p.C10X) variant with Crohn's disease: A study in 3 independent European cohorts
-
DOI 10.1002/ibd.20337
-
Büning, C., Schmidt, H. H., Molnár, T., Drenth, J. P., Fiedler, T., Gentz, E. et al. No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts. Inflamm. Bowel. Dis. 14, 332-337 (2008). (Pubitemid 351441321)
-
(2008)
Inflammatory Bowel Diseases
, vol.14
, Issue.3
, pp. 332-337
-
-
Buning, C.1
Schmidt, H.H.-J.2
Molnar, T.3
Drenth, J.P.H.4
Fiedler, T.5
Gentz, E.6
Todorov, T.7
Baumgart, D.C.8
Sturm, A.9
Nagy, F.10
Lonovics, J.11
De Jong, D.J.12
Landt, O.13
Kage, A.14
Nickel, R.15
Buttner, J.16
Lochs, H.17
Witt, H.18
-
29
-
-
42649102331
-
Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation
-
DOI 10.1038/sj.ejhg.5201996, PII 5201996
-
Bagnall, R. D., Roberts, R. G., Mirza, M. M., Torigoe, T., Prescott, N. J. & Mathew, C. G. Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation. Eur. J. Hum. Genet. 16, 619-625 (2008). (Pubitemid 351594129)
-
(2008)
European Journal of Human Genetics
, vol.16
, Issue.5
, pp. 619-625
-
-
Bagnall, R.D.1
Roberts, R.G.2
Mirza, M.M.3
Torigoe, T.4
Prescott, N.J.5
Mathew, C.G.6
-
30
-
-
43049159804
-
Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project)
-
Kastbom, A., Verma, D., Eriksson, P., Skogh, T., Wingren, G. & Söderkvist, P. Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project). Rheumatology47, 415-417 (2008).
-
(2008)
Rheumatology
, vol.47
, pp. 415-417
-
-
Kastbom, A.1
Verma, D.2
Eriksson, P.3
Skogh, T.4
Wingren, G.5
Söderkvist, P.6
-
31
-
-
40549084310
-
Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation relation to common inflammatory diseases?
-
DOI 10.1002/art.23286
-
Verma, D., Lerm, M., Blomgran Julinder, R., Eriksson, P., Söderkvist, P. & Särndahl, E. Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases? Arthritis. Rheum. 58, 888-894 (2008). (Pubitemid 351364891)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.3
, pp. 888-894
-
-
Verma, D.1
Lerm, M.2
Julinder, R.B.3
Eriksson, P.4
Soderkvist, P.5
Sarndahl, E.6
-
32
-
-
66949174089
-
Combined polymorphisms in genes encodingthe inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men
-
Schoultz, I., Verma, D., Halfvarsson, J., Törkvist, L., Fredrikson, M., Sjöqvist, U. et al. Combined polymorphisms in genes encodingthe inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. Am. J. Gastro-enterol. 104, 1180-1188 (2009).
-
(2009)
Am. J. Gastro-enterol.
, vol.104
, pp. 1180-1188
-
-
Schoultz, I.1
Verma, D.2
Halfvarsson, J.3
Törkvist, L.4
Fredrikson, M.5
Sjöqvist, U.6
-
33
-
-
77953122347
-
Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease
-
Roberts, R. L., Topless, R. K., Phipps-Green, A. J., Gearry, R. B., Barclay M. L. & Merriman, T. R. Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease. Genes. Immun. 11, 351-356 (2010).
-
(2010)
Genes. Immun.
, vol.11
, pp. 351-356
-
-
Roberts, R.L.1
Topless, R.K.2
Phipps-Green, A.J.3
Gearry, R.B.4
Barclay, M.L.5
Merriman, T.R.6
-
34
-
-
33749261760
-
Association of TNF-α/LTA polymorphisms with Crohn's disease in Koreans
-
DOI 10.1016/j.cyto.2006.07.002, PII S1043466606002079
-
Yang, S. K., Lee, S. G., Cho, Y K., Lim, J., Lee, I. & Song, K. Association of TNF-alpha/LTA polymorphisms with Crohn's disease in Koreans. Cytokine 35, 13-20 (2006). (Pubitemid 44485530)
-
(2006)
Cytokine
, vol.35
, Issue.1-2
, pp. 13-20
-
-
Yang, S.-K.1
Lee, S.-G.2
Cho, Y.-K.3
Lim, J.4
Lee, I.5
Song, K.6
-
35
-
-
44949240320
-
Association of TNFSF15 with Crohn's disease in Koreans
-
DOI 10.1111/j.1572-0241.2007.01752.x
-
Yang, S. K., Lim, J., Chang, H. S., Lee, I., Li, Y., Liu, J. et al. Association of TNFSF15 with Crohn's disease in Koreans. Am. J. Gastroenterol. 103, 1437-1442 (2008). (Pubitemid 351813898)
-
(2008)
American Journal of Gastroenterology
, vol.103
, Issue.6
, pp. 1437-1442
-
-
Yang, S.-K.1
Lim, J.2
Chang, H.-S.3
Lee, I.4
Li, Y.5
Liu, J.6
Song, K.7
-
36
-
-
70449719062
-
Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans
-
Yang, S. K., Park, M., Lim, J., Park, S. H., Ye, B. D., Lee, I. et al. Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans. Inflamm. Bowel Dis. 15, 1385-1390 (2009).
-
(2009)
Inflamm. Bowel Dis.
, vol.15
, pp. 1385-1390
-
-
Yang, S.K.1
Park, M.2
Lim, J.3
Park, S.H.4
Ye, B.D.5
Lee, I.6
-
38
-
-
33947524257
-
Clinical features and natural history of ulcerative colitis in Korea
-
Park, S. H., Kim, Y M., Yang, S. K., Kim, S. H., Byeon, J. S., Myung, S. J. et al. Clinical features and natural history of ulcerative colitis in Korea. Inflamm. Bowel Dis. 13, 278-283 (2007).
-
(2007)
Inflamm. Bowel Dis.
, vol.13
, pp. 278-283
-
-
Park, S.H.1
Kim, Y.M.2
Yang, S.K.3
Kim, S.H.4
Byeon, J.S.5
Myung, S.J.6
-
39
-
-
77956607238
-
Clinical features and long-term prognosis of Crohn's disease in Korea
-
Ye, B. D., Yang, S. K., Cho, Y K., Park, S. H., Yang, D. H., Yoon, S. M et al. Clinical features and long-term prognosis of Crohn's disease in Korea. Scand. J. Gastroenterol. 45, 1178-1185 (2010).
-
(2010)
Scand. J. Gastroenterol.
, vol.45
, pp. 1178-1185
-
-
Ye, B.D.1
Yang, S.K.2
Cho, Y.K.3
Park, S.H.4
Yang, D.H.5
Yoon, S.M.6
-
40
-
-
84894353884
-
Toward an integrated clinical molecular and serological classification of inflam-matory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg, M. S., Satsangi, J., Ahmad, T., Arnott, I. D., Bernstein, C. N., Brant, S. R. et al. Toward an integrated clinical molecular and serological classification of inflam-matory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can. J. Gastroenterol. 19 (Suppl A), 5A-36A (2005).
-
(2005)
Can. J. Gastroenterol.
, vol.19
, Issue.SUPPL. A
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
Arnott, I.D.4
Bernstein, C.N.5
Brant, S.R.6
-
41
-
-
34548292504
-
PLINK: Atool setforwhole-genomeassociation and population-based linkageanalyses
-
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A., Bender, D. et al. PLINK: atool setforwhole-genomeassociation and population-based linkageanalyses. Am. J. Hum. Genet. 81, 559-575 (2007).
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
-
42
-
-
0035897904
-
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
-
DOI 10.1016/S0140-6736(00)05063-7
-
Hampe, J., Cuthbert, A., Croucher, P. J., Mirza, M. M., Mascheretti, S., Fisher, S. et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet357, 1925-1928 (2001). (Pubitemid 32568333)
-
(2001)
Lancet
, vol.357
, Issue.9272
, pp. 1925-1928
-
-
Hampe, J.1
Cuthbert, A.2
Croucher, P.J.P.3
Mirza, M.M.4
Mascheretti, S.5
Fisher, S.6
Frenzel, H.7
King, K.8
Hasselmeyer, A.9
MacPherson, A.J.S.10
Bridger, S.11
Van Deventer, S.12
Forbes, A.13
Nikolaus, S.14
Lennard-Jones, J.E.15
Foelsch, U.R.16
Krawczak, M.17
Lewis, C.18
Schreiber, S.19
Mathew, C.G.20
more..
-
43
-
-
0035978651
-
Association of NOD2 leucine-rich repeatvariantswith susceptibilityto Crohn's disease
-
Hugot, J. P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J. P., Belaiche, J. et al. Association of NOD2 leucine-rich repeatvariantswith susceptibilityto Crohn's disease. Nature411, 599-603 (2003).
-
(2003)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cézard, J.P.5
Belaiche, J.6
-
44
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
DOI 10.1038/35079114
-
Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R. et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606 (2001). (Pubitemid 32531409)
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.-P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nuez, G.16
Cho, J.H.17
-
45
-
-
0036306951
-
Lack of common NOD2 variants in Japanese patients with Crohn's disease
-
DOI 10.1053/gast.2002.34155
-
Inoue, N., Tamura, K., Kinouchi, Y., Fukuda, Y., Takahashi, S., Ogura, Y et al. Lack of common NOD2 variants in Japanese patients with Crohn's disease. Gastroenterology 123, 86-91 (2002). (Pubitemid 34747528)
-
(2002)
Gastroenterology
, vol.123
, Issue.1
, pp. 86-91
-
-
Inoue, N.1
Tamura, K.2
Kinouchi, Y.3
Fukuda, Y.4
Takahashi, S.5
Ogura, Y.6
Inohara, N.7
Nuez, G.8
Kishi, Y.9
Koike, Y.10
Shimosegawa, T.11
Shimoyama, T.12
Hibi, T.13
-
46
-
-
0038235697
-
NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population
-
DOI 10.1046/j.1365-2036.2003.01607.x
-
Leong, R. W., Armuzzi, A., Ahmad, T., Wong, M. L., Tse, P., Jewell, D. P. et al. NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population. Aliment. Pharmacol. Ther. 17, 1465-1470 (2003). (Pubitemid 36831437)
-
(2003)
Alimentary Pharmacology and Therapeutics
, vol.17
, Issue.12
, pp. 1465-1470
-
-
Leong, R.W.L.1
Armuzzi, A.2
Ahmad, T.3
Wong, M.L.4
Tse, P.5
Jewell, D.P.6
Sung, J.J.Y.7
-
47
-
-
0037265610
-
Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations
-
DOI 10.1038/sj.ejhg.5200897
-
Croucher, P. J., Mascheretti, S., Hampe, J., Huse, K., Frenzel, H., Stoll, M. et al. Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnicallydivergent populations. Eur. J. Hum. Genet. 11, 6-16 (2003). (Pubitemid 36175778)
-
(2003)
European Journal of Human Genetics
, vol.11
, Issue.1
, pp. 6-16
-
-
Croucher, P.J.P.1
Mascheretti, S.2
Hampe, J.3
Huse, K.4
Frenzel, H.5
Stoll, M.6
Lu, T.7
Nikolaus, S.8
Yang, S.-K.9
Krawczak, M.10
Kim, W.H.11
Schreiber, S.12
-
48
-
-
58149390157
-
An update on the epidemiology of inflammatory bowel disease in Asia
-
Thia, K. T., Loftus, Jr. E. V., Sandborn, W. J. & Yang, S. K. An update on the epidemiology of inflammatory bowel disease in Asia. Am. J. Gastroenterol. 103, 3167-3182 (2008).
-
(2008)
Am. J. Gastroenterol.
, vol.103
, pp. 3167-3182
-
-
Thia, K.T.1
Loftus Jr., E.V.2
Sandborn, W.J.3
Yang, S.K.4
-
49
-
-
42449141463
-
Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: A KASID study
-
DOI 10.1002/ibd.20310
-
Yang, S. K., Yun, S., Kim, J. H., Park, J. Y., Kim, H. Y., Kim, Y H. et al. Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: a KASID study. Inflamm. Bowel Dis. 14, 542-549 (2008). (Pubitemid 351571835)
-
(2008)
Inflammatory Bowel Diseases
, vol.14
, Issue.4
, pp. 542-549
-
-
Yang, S.-K.1
Yun, S.2
Kim, J.-H.3
Joon, Y.P.4
Hak, Y.K.5
Kim, Y.-H.6
Dong, K.C.7
Joo, S.K.8
In, S.S.9
Jong, B.P.10
Park, E.-R.11
Kyung, J.K.12
Moon, G.13
Soo, H.Y.14
-
50
-
-
0033785374
-
Crohn's disease in Japan: Diagnostic criteria and epidemiology
-
Yao, T., Matsui, T. & Hiwatashi, N. Crohn's disease in Japan: diagnostic criteria and epidemiology. Dis. Colon. Rectum. 43, S85-S93 (2000).
-
(2000)
Dis. Colon. Rectum.
, vol.43
-
-
Yao, T.1
Matsui, T.2
Hiwatashi, N.3
|