CK2 phosphorylation of an acidic Ser/Thr Di-isoleucine motif in the Na +/H+ exchanger NHE5 isoform promotes association with β-arrestin2 and endocytosis

Journal of Biological Chemistry

Volumn 286, Issue 13, 2011, Pages 11456-11468

  Lukashova, Viktoria ^a   Szabó, Elöd Z ^b   Jinadasa, Tushare ^a   Mokhov, Alexei ^a   Litchfield, David W ^c   Orlowski, John ^a  

^a MCGILL UNIVERSITY   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; C TERMINUS; COUPLED RECEPTORS; DISCRETE ELEMENTS; IN-VITRO; IN-VITRO ANALYSIS; INTACT CELLS; ISOFORMS; OVER-EXPRESSION; PROTEIN KINASE CK2; RECYCLING ENDOSOMES; SORTING SIGNALS; TRANSFECTED CELLS; WILD TYPES;

ENZYMES; MOLECULAR BIOLOGY; PHOSPHORYLATION; RECYCLING; SODIUM;

AMINO ACIDS;

BETA ARRESTIN 2; CASEIN KINASE II; G PROTEIN COUPLED RECEPTOR KINASE 2; ISOLEUCINE; SERINE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 5; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHO CELL; COMPLEX FORMATION; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ARRESTINS; CASEIN KINASE I; CASEIN KINASE II; CELL LINE; ENDOCYTOSIS; ENDOSOMES; G-PROTEIN-COUPLED RECEPTOR KINASE 2; HUMANS; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SODIUM-HYDROGEN ANTIPORTER;

EID: 79953216756     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.182881     Document Type: Article

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