Arrestins and spinophilin competitively regulate Na+,K +-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase

Molecular Biology of the Cell

Volumn 18, Issue 11, 2007, Pages 4508-4518

  Kimura, Tohru ^a   Allen, Patrick B ^a   Nairn, Angus C ^a   Caplan, Michael J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ARRESTIN 2; ARRESTIN 3; BETA ARRESTIN; DOPAMINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; PROTEIN 14 3 3; PROTEIN 14 3 3EPSILON; RETINA S ANTIGEN; SPINOPHILIN; UNCLASSIFIED DRUG; VASOPRESSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENETIC TRANSFECTION; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM;

14-3-3 PROTEINS; ANIMALS; ARRESTIN; BINDING, COMPETITIVE; CELL LINE; CERCOPITHECUS AETHIOPS; CHOROID PLEXUS; CYTOPLASM; G-PROTEIN-COUPLED RECEPTOR KINASES; KIDNEY; MICE; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN SUBUNITS; PROTEIN TRANSPORT; RABBITS; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 35848934128     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E06-08-0711     Document Type: Article

References (60)

1. Allen, P. B., Ouimet, C. C., and Greengard, P. (1997). Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc. Natl. Acad. Sci. USA 94, 9956-9961.
2. +-ATPase activity in rat proximal convoluted tubule segments. Am. J. Physiol. 252, F39-F45.
3. Attramadal, H., Arriza, J. L., Aoki, C., Dawson, T. M., Codina, J., Kwatra, M. M., Snyder, S. H., Caron, M. G., and Lefkowitz, R. J. (1992). Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. J. Biol. Chem. 267, 17882-17890.
4. Barnes, A. D., and Drangova, R. (1997). Regulation of sodium transport by endogenous dopamine production in proximal tubular and OK cells. Clin. Exp. Hypertens. 19, 87-91.
5. Bertorello, A. M., and Katz, A. I. (1993). Short-term regulation of renal Na-K-ATPase activity: physiological relevance and cellular mechanisms. Am. J. Physiol. 265, F743-F755.
6. Biemesderfer, D., Dekan, G., Aronson, P. S., and Farquhar, M. G. (1992). Assembly of distinctive coated pit and microvillar microdomains in the renal brush border. Am. J. Physiol. 262, F55-F67.
7. Brady, A. E., Wang, Q., Colbran, R. J., Allen, P. B., Greengard, P., and Limbird, L. E. (2003). Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors. J. Biol. Chem. 278, 32405-32412.
8. Brismar, H., Agren, M., and Holtback, U. (2002). beta-Adrenoceptor agonist sensitizes the dopamine-1 receptor in renal tubular cells. Acta Physiol. Scand. 175, 333-340.
9. Chen, W., Kirkbride, K. C., How, T., Nelson, C. D., Mo, J., Frederick, J. P., Wang, X. F., Lefkowitz, R. J., and Blobe, G. C. (2003). Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling. Science 301, 1394-1397.
10. Chibalin, A. V., Katz, A. I., Berggren, P. O., and Bertorello, A. M. (1997). Receptor-mediated inhibition of renal Na(+)-K(+)-ATPase is associated with endocytosis of its alpha- and beta-subunits. Am. J. Physiol. 273, C1458-C1465.
11. +,K+-ATPase is initiated by phosphorylation of Ser-18 in the rat alpha subunit and is responsible for the decreased activity in epithelial cells. J. Biol. Chem. 274, 1920-1927.
12. Claing, A., Laporte, S. A., Caron, M. G., and Lefkowitz, R. J. (2002). Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Prog. Neurobiol. 66, 61-79.
13. Couve, A., Kittler, J. T., Uren, J. M., Calver, A. R., Pangalos, M. N., Walsh, F. S., and Moss, S. J. (2001). Association of GABA(B) receptors and members of the 14-3-3 family of signaling proteins. Mol. Cell Neurosci. 17, 317-328.
14. Djelidi, S., Beggah, A., Courtois-Coutry, N., Fay, M., Cluzeaud, F., Viengchareun, S., Bonvalet, J. P., Farman, N., and Blot-Chabaud, M. (2001). Basolateral translocation by vasopressin of the aldosterone-induced pool of latent Na-K-ATPases is accompanied by alphal subunit dephosphorylation: study in a new aldosterone-sensitive rat cortical collecting duct cell line. J. Am. Soc. Nephrol. 12, 1805-1818.
15. Dmitrieva, R. I., and Doris, P. A. (2003). Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells. J. Biol. Chem. 278, 28160-28166.
16. Dunbar, L. A., Aronson, P., and Caplan, M. J. (2000). A transmembrane segment determines the steady-state localization of an ion-transporting adenosine triphosphatase. J. Cell Biol. 148, 769-778.
17. +-ATPase α1-subunit phosphorylation signal into binding and activation of phosphoinositide 3-kinase during endocytosis. J. Biol. Chem. 280, 16272-16277.
18. Fishman, M. C. (1979). Endogenous digitalis-like activity in mammalian brain. Proc. Natl. Acad. Sci. USA 76, 4661-4663.
19. Gomes, P., and Soares-da-Silva, P. (2004). Dopamine acutely decreases type 3 Na(+)/H(+) exchanger activity in renal OK cells through the activation of protein kinases A and C signalling cascades. Eur. J. Pharmacol. 488, 51-59.
20. Gottardi, C. J., and Caplan, M. J. (1993). Molecular requirements for the cell-surface expression of multisubunit ion-transporting ATPases. Identification of protein domains that participate in Na,K-ATPase and H,K-ATPase subunit assembly. J. Biol. Chem. 268, 14342-14347.
21. Haupert, G. T., Jr., and Sancho, J. M. (1979). Sodium transport inhibitor from bovine hypothalamus. Proc. Natl. Acad. Sci. USA 76, 4658-4660.
22. Ishii, T., Lemas, M. V., and Takeyasu, K. (1994). Na(+)-, ouabain-, Ca(2+)-, and thapsigargin-sensitive ATPase activity expressed in chimeras between the calcium and the sodium pump alpha subunits. Proc. Natl. Acad. Sci. USA 91, 6103-6107.
23. Khundmiri, S. J., and Lederer, E. (2002). PTH and DA regulate Na-K ATPase through divergent pathways. Am. J. Physiol. Renal Physiol. 282, F512-F522.
24. Lefkowitz, R. J., and Shenoy, S. K. (2005). Transduction of receptor signals by beta-arrestins. Science 308, 512-517.
25. Li, D., Aperia, A., Celsi, G., da Cruz e Silva, E. F., Greengard, P., and Meister, B. (1995). Protein phosphatase-1 in the kidney: evidence for a role in the regulation of medullary Na(+)-K(+)-ATPase. Am. J. Physiol. 269, F673-F680.
26. Lichtstein, D., and Samuelov, S. (1980). Endogenous 'ouabain like' activity in rat brain. Biochem. Biophys. Res. Commun. 96, 1518-1523.
27. Lichtstein, D., Samuelov, S., Gati, I., and Wechter, W. J. (1992). Digitalis-like compounds in animal tissues. J. Basic Clin. Physiol. Pharmacol. 3, 269-292.
28. Lin, F. T., Daaka, Y., and Lefkowitz, R. J. (1998). beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. J. Biol. Chem. 273, 31640-31643.
29. Liu, F., and Gesek, F. A. (2001). alpha(1)-Adrenergic receptors activate NHE1 and NHE3 through distinct signaling pathways in epithelial cells. Am. J. Physiol. Renal Physiol. 280, F415-F425.
30. Liu, F., Nesbitt, T., Drezner, M. K., Friedman, P. A., and Gesek, F. A. (1997). Proximal nephron Na+/H+ exchange is regulated by alpha 1A- and alpha 1B-adrenergic receptor subtypes. Mol. Pharmacol. 52, 1010-1018.
31. Mallick, B. N., Adya, H. V., and Faisal, M. (2000). Norepinephrine- stimulated increase in Na+,K+-ATPase activity in the rat brain is mediated through alphalA-adrenoceptor possibly by dephosphorylation of the enzyme. J. Neurochem. 74, 1574-1578.
32. +-ATPase in the choroid plexus. Brain Res. 302, 357-362.
33. Narkar, V. A., Hussain, T., and Lokhandwala, M. F. (2002). Activation of D2-like receptors causes recruitment of tyrosine-phosphorylated NKA alpha 1-subunits in kidney. Am. J. Physiol. Renal Physiol. 283, F1290-F1295.
34. Ohtsubo, M., Noguchi, S., Takeda, K., Morohashi, M., and Kawamura, M. (1990). Site-directed mutagenesis of Asp-376, the catalytic phosphorylation site, and Lys-507, the putative ATP-binding site, of the alpha-subunit of Torpedo californica Na+/K(+)-ATPase. Biochim. Biophys. Acta 1021, 157-160.
35. Pagel, P., Zatti, A., Kimura, T., Duffield, A., Chauvet, V., Rajendran, V., and Caplan, M. J. (2003). Ion pump-interacting proteins: promising new partners. Ann. NY Acad. Sci. 986, 360-368.
36. Parruti, G., Peracchia, F., Sallese, M., Ambrosini, G., Masini, M., Rotilio, D., and De Blasi, A. (1993). Molecular analysis of human beta-arrestin-1, cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing. J. Biol. Chem. 268, 9753-9761.
37. Pedrosa, R., Gomes, P., and Soares-da-Silva, P. (2004). Distinct signalling cascades downstream to Gsalpha coupled dopamine D1-like NHE3 inhibition in rat and opossum renal epithelial cells. Cell Physiol. Biochem. 14, 91-100.
38. Pietrini, G., Matteoli, M., Banker, G., and Caplan, M. J. (1992). Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture. Proc. Natl. Acad. Sci. USA 89, 8414-8418.
39. Pinto-do, O. P., Chibalin, A. V., Katz, A. I., Soares-da-Silva, P., and Bertorello, A.M. (1997). Short-term vs. sustained inhibition of proximal tubule Na,K-ATPase activity by dopamine: cellular mechanisms. Clin. Exp. Hypertens. 19, 73-86.
40. Prezeau, L., Richman, J. G., Edwards, S. W., and Limbird, L. E. (1999). The zeta isoform of 14-3-3 proteins interacts with the third intracellular loop of different alpha2-adrenergic receptor subtypes. J. Biol. Chem. 274, 13462-13469.
41. Richman, J. G., Brady, A. E., Wang, Q., Hensel, J. L., Colbran, R. J., and Limbird, L. E. (2001). Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin. J. Biol. Chem. 276, 15003-15008.
42. 2+-ATPase pump. J. Biol. Chem. 280, 37195-37203.
43. Satoh, A. et al. (1998). Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites. J. Biol. Chem. 273, 3470-3475.
44. Scheiner-Bobis, G., and Farley, R. A. (1994). Subunit requirements for expression of functional sodium pumps in yeast cells. Biochim. Biophys. Acta 1193, 226-234.
45. Shenoy, S. K., and Lefkowitz, R. J. (2003). Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem. J. 375, 503-515.
46. +)-ATPase catalytic unit, characterization of antiserum, and immunocytochemical localization in cerebellum, choroid plexus, and kidney. J. Histochem. Cytochem. 32, 1309-1318.
47. Skou, J. C., and Esmann, M. (1992). The Na,K-ATPase. J. Bioenerget. Biomembr. 24, 249-261.
48. Smith, F. D., Oxford, G. S., and Milgram, S. L. (1999). Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein. J. Biol. Chem. 274, 19894-19900.
49. Stephens, D. J., and Banting, G. (1999). Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin. J. Biol. Chem. 274, 30080-30086.
50. Sterne-Marr, R., and Benovic, J. L. (1995). Regulation of G protein-coupled receptors by receptor kinases and arrestins. Vitam. Horm. 51, 193-234.
51. + exchanger NHE5 isoform. Proc. Natl. Acad. Sci. USA 102, 2790-2795.
52. Tan, C. M., Brady, A. E., Nickols, H. H., Wang, Q., and Limbird, L. E. (2004). Membrane trafficking of G protein-coupled receptors. Annu. Rev. Pharmacol. Toxicol. 44, 559-609.
53. Tazawa, H., Takahashi, S., and Zilliacus, J. (2003). Interaction of the parathyroid hormone receptor with the 14-3-3 protein. Biochim. Biophys. Acta 1620, 32-38.
54. Therien, A. G., and Blostein, R. (2000). Mechanisms of sodium pump regulation. Am. J. Physiol. Cell Physiol. 279, C541-C566.
55. Toyoshima, C., and Mizutani, T. (2004). Crystal structure of the calcium pump with a bound ATP analogue. Nature 430, 529-535.
56. Wang, Q., and Limbird, L. E. (2002). Regulated interactions of the alpha 2A adrenergic receptor with spinophilin, 14-3-3zeta, and arrestin 3. J. Biol. Chem. 277, 50589-50596.
57. Wang, Q., Zhao, J., Brady, A. E., Feng, J., Allen, P. B., Lefkowitz, R. J., Greengard, P., and Limbird, L. E. (2004a). Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors. Science 304, 1940-1944.
58. + transporters in rats with PTH-induced hypercalcemia. Am. J. Physiol. Renal Physiol. 286, F534-F545.
59. Wu, J. H., Peppel, K., Nelson, C. D., Lin, F. T., Kohout, T. A., Miller, W. E., Exum, S. T., and Freedman, N. J. (2003). The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. J. Biol. Chem. 278, 44238-44245.
60. Xie, Z., and Cai, T. (2003). Na+-K+-ATPase-mediated signal transduction: from protein interaction to cellular function. Mol. Interv. 3, 157-168.