Peroxisome proliferator-activated receptor γ negatively regulates IFN-β production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-β promoter

Journal of Biological Chemistry

Volumn 286, Issue 7, 2011, Pages 5519-5528

  Zhao, Wei ^a   Wang, Lijuan ^a   Zhang, Meng ^a   Wang, Peng ^a   Zhang, Lei ^a   Yuan, Chao ^a   Qi, Jianni ^a   Qiao, Yu ^a   Kuo, Paul C ^b   Gao, Chengjiang ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL INFECTIONS; CHROMATIN IMMUNOPRECIPITATION ASSAY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; IMMUNE CELLS; IN-VIVO; INTERFERON REGULATORY FACTOR 3; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROINFLAMMATORY CYTOKINES; TOLL-LIKE RECEPTORS; TRANSCRIPTIONAL REPRESSORS;

ANTIBIOTICS; CYTOLOGY; ELECTROPHORETIC MOBILITY; GLYCOPROTEINS; MACROPHAGES; PHOSPHORYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

INTERFERONS;

BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAT1 PROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TROGLITAZONE;

ARTICLE; BINDING AFFINITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GEL MOBILITY SHIFT ASSAY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMANS; FEMALE; INTERFERON INDUCERS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; PHOSPHORYLATION; POLY I-C; PPAR GAMMA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; STAT1 TRANSCRIPTION FACTOR; THIAZOLIDINEDIONES; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); MUS;

EID: 79953142333     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.149823     Document Type: Article

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