메뉴 건너뛰기




Volumn 1, Issue 12, 2010, Pages 1106-1117

Mechanism of inhibiting type I interferon induction by hepatitis B virus X protein

Author keywords

deubiquitination; HBV X protein (HBx); hepatitis B virus (HBV); type I interferon

Indexed keywords

DEUBIQUITINATING ENZYME; ENZYME; HEPATITIS B VIRUS X PROTEIN; I KAPPA B KINASE EPSILON; I KAPPA B KINASE GAMMA; INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; RETINOIC ACID INDUCIBLE PROTEIN I; TANK BINDING KINASE 1; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG;

EID: 79953137779     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-010-0141-8     Document Type: Article
Times cited : (87)

References (50)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira, S., Uematsu, S., and Takeuchi, O. (2006). Pathogen recognition and innate immunity. Cell 124, 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 63649116570 scopus 로고    scopus 로고
    • Ubiquitylation in innate and adaptive immunity
    • Bhoj, V. G., and Chen, Z. J. (2009). Ubiquitylation in innate and adaptive immunity. Nature 458, 430-437.
    • (2009) Nature , vol.458 , pp. 430-437
    • Bhoj, V.G.1    Chen, Z.J.2
  • 3
    • 8644274040 scopus 로고    scopus 로고
    • The enigmatic X gene of hepatitis B virus
    • Bouchard, M. J., and Schneider, R. J. (2004). The enigmatic X gene of hepatitis B virus. J Virol 78, 12725-12734.
    • (2004) J Virol , vol.78 , pp. 12725-12734
    • Bouchard, M.J.1    Schneider, R.J.2
  • 4
    • 56749133272 scopus 로고    scopus 로고
    • Viral evasion and subversion of pattern-recognition receptor signalling
    • Bowie, A. G., and Unterholzner, L. (2008). Viral evasion and subversion of pattern-recognition receptor signalling. Nat Rev Immunol 8, 911-922.
    • (2008) Nat Rev Immunol , vol.8 , pp. 911-922
    • Bowie, A.G.1    Unterholzner, L.2
  • 5
    • 33845770748 scopus 로고    scopus 로고
    • Inhibition of alpha interferon signaling by hepatitis B virus
    • Christen, V., Duong, F., Bernsmeier, C., Sun, D., Nassal, M., and Heim, M. H. (2007). Inhibition of alpha interferon signaling by hepatitis B virus. J Virol 81, 159-165.
    • (2007) J Virol , vol.81 , pp. 159-165
    • Christen, V.1    Duong, F.2    Bernsmeier, C.3    Sun, D.4    Nassal, M.5    Heim, M.H.6
  • 6
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Dienstag, J. L. (2008). Hepatitis B virus infection. N Engl J Med 359, 1486-1500.
    • (2008) N Engl J Med , vol.359 , pp. 1486-1500
    • Dienstag, J.L.1
  • 8
    • 0043169550 scopus 로고    scopus 로고
    • Hepatitis B virus downregulates the human interferon-inducible MxA promoter through direct interaction of precore/core proteins
    • Fernández, M., Quiroga, J. A., and Carreño, V. (2003). Hepatitis B virus downregulates the human interferon-inducible MxA promoter through direct interaction of precore/core proteins. J Gen Virol 84, 2073-2082.
    • (2003) J Gen Virol , vol.84 , pp. 2073-2082
    • Fernández, M.1    Quiroga, J.A.2    Carreño, V.3
  • 13
    • 34249058290 scopus 로고    scopus 로고
    • Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
    • Guo, B., and Cheng, G. (2007). Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J Biol Chem 282, 11817-11826.
    • (2007) J Biol Chem , vol.282 , pp. 11817-11826
    • Guo, B.1    Cheng, G.2
  • 14
    • 50149117189 scopus 로고    scopus 로고
    • Intrahepatic expression of genes affiliated with innate and adaptive immune responses immediately after invasion and during acute infection with woodchuck hepadnavirus
    • Guy, C. S., Mulrooney-Cousins, P. M., Churchill, N. D., and Michalak, T. I. (2008). Intrahepatic expression of genes affiliated with innate and adaptive immune responses immediately after invasion and during acute infection with woodchuck hepadnavirus. J Virol 82, 8579-8591.
    • (2008) J Virol , vol.82 , pp. 8579-8591
    • Guy, C.S.1    Mulrooney-Cousins, P.M.2    Churchill, N.D.3    Michalak, T.I.4
  • 15
    • 63649113699 scopus 로고    scopus 로고
    • Origin and function of ubiquitin-like proteins
    • Hochstrasser, M. (2009). Origin and function of ubiquitin-like proteins. Nature 458, 422-429.
    • (2009) Nature , vol.458 , pp. 422-429
    • Hochstrasser, M.1
  • 16
    • 33748475531 scopus 로고    scopus 로고
    • Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
    • Honda, K., Takaoka, A., and Taniguchi, T. (2006). Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25, 349-360.
    • (2006) Immunity , vol.25 , pp. 349-360
    • Honda, K.1    Takaoka, A.2    Taniguchi, T.3
  • 17
    • 69049086481 scopus 로고    scopus 로고
    • TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
    • Kawagoe, T., Takeuchi, O., Takabatake, Y., Kato, H., Isaka, Y., Tsujimura, T., and Akira, S. (2009). TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 10, 965-972.
    • (2009) Nat Immunol , vol.10 , pp. 965-972
    • Kawagoe, T.1    Takeuchi, O.2    Takabatake, Y.3    Kato, H.4    Isaka, Y.5    Tsujimura, T.6    Akira, S.7
  • 18
    • 5444274514 scopus 로고    scopus 로고
    • Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
    • Kawai, T., Sato, S., Ishii, K. J., Coban, C., Hemmi, H., Yamamoto, M., Terai, K., Matsuda, M., Inoue, J., Uematsu, S., et al. (2004). Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 5, 1061-1068.
    • (2004) Nat Immunol , vol.5 , pp. 1061-1068
    • Kawai, T.1    Sato, S.2    Ishii, K.J.3    Coban, C.4    Hemmi, H.5    Yamamoto, M.6    Terai, K.7    Matsuda, M.8    Inoue, J.9    Uematsu, S.10
  • 20
    • 20444442721 scopus 로고    scopus 로고
    • Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes
    • Li, K., Chen, Z., Kato, N., Gale, M. Jr, and Lemon, S. M. (2005). Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem 280, 16739-16747.
    • (2005) J Biol Chem , vol.280 , pp. 16739-16747
    • Li, K.1    Chen, Z.2    Kato, N.3    Gale Jr., M.4    Lemon, S.M.5
  • 21
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • Lok, A. S., and McMahon, B. J. (2007). Chronic hepatitis B. Hepatology 45, 507-539.
    • (2007) Hepatology , vol.45 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 22
    • 58049202928 scopus 로고    scopus 로고
    • Viral sensors: diversity in pathogen recognition
    • McCartney, S. A., and Colonna, M. (2009). Viral sensors: diversity in pathogen recognition. Immunol Rev 227, 87-94.
    • (2009) Immunol Rev , vol.227 , pp. 87-94
    • McCartney, S.A.1    Colonna, M.2
  • 23
    • 35349016235 scopus 로고    scopus 로고
    • Recognition of microorganisms and activation of the immune response
    • Medzhitov, R. (2007). Recognition of microorganisms and activation of the immune response. Nature 449, 819-826.
    • (2007) Nature , vol.449 , pp. 819-826
    • Medzhitov, R.1
  • 24
    • 0031952176 scopus 로고    scopus 로고
    • Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication
    • Melegari, M., Scaglioni, P. P., and Wands, J. R. (1998). Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. J Virol 72, 1737-1743.
    • (1998) J Virol , vol.72 , pp. 1737-1743
    • Melegari, M.1    Scaglioni, P.P.2    Wands, J.R.3
  • 25
    • 68049085881 scopus 로고    scopus 로고
    • DNA makes RNA makes innate immunity
    • O'Neill, L. A. (2009). DNA makes RNA makes innate immunity. Cell 138, 428-430.
    • (2009) Cell , vol.138 , pp. 428-430
    • O'Neill, L.A.1
  • 26
    • 59449091450 scopus 로고    scopus 로고
    • Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection
    • Oshiumi, H., Matsumoto, M., Hatakeyama, S., and Seya, T. (2009). Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection. J Biol Chem 284, 807-817.
    • (2009) J Biol Chem , vol.284 , pp. 807-817
    • Oshiumi, H.1    Matsumoto, M.2    Hatakeyama, S.3    Seya, T.4
  • 27
    • 33947303068 scopus 로고    scopus 로고
    • Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis
    • Pang, R., Lee, T. K., Poon, R. T., Fan, S. T., Wong, K. B., Kwong, Y. L., and Tse, E. (2007). Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. Gastroenterology 132, 1088-1103.
    • (2007) Gastroenterology , vol.132 , pp. 1088-1103
    • Pang, R.1    Lee, T.K.2    Poon, R.T.3    Fan, S.T.4    Wong, K.B.5    Kwong, Y.L.6    Tse, E.7
  • 28
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
    • Randall, R. E., and Goodbourn, S. (2008). Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J Gen Virol 89, 1-47.
    • (2008) J Gen Virol , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 29
    • 65449183853 scopus 로고    scopus 로고
    • Viral avoidance and exploitation of the ubiquitin system
    • Randow, F., and Lehner, P. J. (2009). Viral avoidance and exploitation of the ubiquitin system. Nat Cell Biol 11, 527-534.
    • (2009) Nat Cell Biol , vol.11 , pp. 527-534
    • Randow, F.1    Lehner, P.J.2
  • 30
    • 67650620318 scopus 로고    scopus 로고
    • Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
    • Reyes-Turcu, F. E., Ventii, K. H., and Wilkinson, K. D. (2009). Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem 78, 363-397.
    • (2009) Annu Rev Biochem , vol.78 , pp. 363-397
    • Reyes-Turcu, F.E.1    Ventii, K.H.2    Wilkinson, K.D.3
  • 32
    • 33744499683 scopus 로고    scopus 로고
    • Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
    • Saitoh, T., Tun-Kyi, A., Ryo, A., Yamamoto, M., Finn, G., Fujita, T., Akira, S., Yamamoto, N., Lu, K. P., and Yamaoka, S. (2006). Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol 7, 598-605.
    • (2006) Nat Immunol , vol.7 , pp. 598-605
    • Saitoh, T.1    Tun-Kyi, A.2    Ryo, A.3    Yamamoto, M.4    Finn, G.5    Fujita, T.6    Akira, S.7    Yamamoto, N.8    Lu, K.P.9    Yamaoka, S.10
  • 33
    • 62549122914 scopus 로고    scopus 로고
    • Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome
    • Schroder, K., Muruve, D. A., and Tschopp, J. (2009). Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome. Curr Biol 19, R262-R265.
    • (2009) Curr Biol , vol.19
    • Schroder, K.1    Muruve, D.A.2    Tschopp, J.3
  • 34
    • 17444430845 scopus 로고    scopus 로고
    • The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication
    • Tang, H., Delgermaa, L., Huang, F., Oishi, N., Liu, L., He, F., Zhao, L., and Murakami, S. (2005). The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication. J Virol 79, 5548-5556.
    • (2005) J Virol , vol.79 , pp. 5548-5556
    • Tang, H.1    Delgermaa, L.2    Huang, F.3    Oishi, N.4    Liu, L.5    He, F.6    Zhao, L.7    Murakami, S.8
  • 35
    • 33847687659 scopus 로고    scopus 로고
    • Multiple functions of the IKKrelated kinase IKKepsilon in interferon-mediated antiviral immunity
    • Tenoever, B. R., Ng, S. L., Chua, M. A., McWhirter, S. M., GarcÍa-Sastre, A., and Maniatis, T. (2007). Multiple functions of the IKKrelated kinase IKKepsilon in interferon-mediated antiviral immunity. Science 315, 1274-1278.
    • (2007) Science , vol.315 , pp. 1274-1278
    • Tenoever, B.R.1    Ng, S.L.2    Chua, M.A.3    McWhirter, S.M.4    García-Sastre, A.5    Maniatis, T.6
  • 36
    • 67649229630 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Nrdp1' preferentially' promotes TLR-mediated production of type I interferon
    • Wang, C., Chen, T., Zhang, J., Yang, M., Li, N., Xu, X., and Cao, X. (2009). The E3 ubiquitin ligase Nrdp1' preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol 10, 744-752.
    • (2009) Nat Immunol , vol.10 , pp. 744-752
    • Wang, C.1    Chen, T.2    Zhang, J.3    Yang, M.4    Li, N.5    Xu, X.6    Cao, X.7
  • 37
    • 77955381494 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion
    • Wang, H., and Ryu, W. S. (2010). Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion. PLoS Pathog 6, e1000986.
    • (2010) PLoS Pathog , vol.6
    • Wang, H.1    Ryu, W.S.2
  • 38
    • 77957679632 scopus 로고    scopus 로고
    • Hepatitis B virus X protein suppresses virus-triggered IRF3 activation and IFNbeta induction by disrupting the VISA-associated complex
    • Wang, X., Li, Y., Mao, A., Li, C., Li, Y., and Tien, P. (2010). Hepatitis B virus X protein suppresses virus-triggered IRF3 activation and IFNbeta induction by disrupting the VISA-associated complex. Cell Mol Immunol 7, 341-348.
    • (2010) Cell Mol Immunol , vol.7 , pp. 341-348
    • Wang, X.1    Li, Y.2    Mao, A.3    Li, C.4    Li, Y.5    Tien, P.6
  • 39
    • 58149498873 scopus 로고    scopus 로고
    • PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling
    • Weber, S., Maass, F., Schuemann, M., Krause, E., Suske, G., and Bauer, U. M. (2009). PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling. Genes Dev 23, 118-132.
    • (2009) Genes Dev , vol.23 , pp. 118-132
    • Weber, S.1    Maass, F.2    Schuemann, M.3    Krause, E.4    Suske, G.5    Bauer, U.M.6
  • 41
    • 77955496554 scopus 로고    scopus 로고
    • The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein
    • Wei, C., Ni, C., Song, T., Liu, Y., Yang, X., Zheng, Z., Jia, Y., Yuan, Y., Guan, K., Xu, Y., et al. (2010). The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J Immunol 185, 1158-1168.
    • (2010) J Immunol , vol.185 , pp. 1158-1168
    • Wei, C.1    Ni, C.2    Song, T.3    Liu, Y.4    Yang, X.5    Zheng, Z.6    Jia, Y.7    Yuan, Y.8    Guan, K.9    Xu, Y.10
  • 42
    • 0025953943 scopus 로고
    • Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene
    • Whitten, T. M., Quets, A. T., and Schloemer, R. H. (1991). Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene. J Virol 65, 4699-4704.
    • (1991) J Virol , vol.65 , pp. 4699-4704
    • Whitten, T.M.1    Quets, A.T.2    Schloemer, R.H.3
  • 43
    • 2342588229 scopus 로고    scopus 로고
    • Genomic analysis of the host response to hepatitis B virus infection
    • Wieland, S., Thimme, R., Purcell, R. H., and Chisari, F. V. (2004). Genomic analysis of the host response to hepatitis B virus infection. Proc Natl Acad Sci U S A 101, 6669-6674.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6669-6674
    • Wieland, S.1    Thimme, R.2    Purcell, R.H.3    Chisari, F.V.4
  • 44
    • 22544481160 scopus 로고    scopus 로고
    • Stealth and cunning: hepatitis B and hepatitis C viruses
    • Wieland, S. F., and Chisari, F. V. (2005). Stealth and cunning: hepatitis B and hepatitis C viruses. J Virol 79, 9369-9380.
    • (2005) J Virol , vol.79 , pp. 9369-9380
    • Wieland, S.F.1    Chisari, F.V.2
  • 45
    • 65449117568 scopus 로고    scopus 로고
    • Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells
    • Wu, J., Meng, Z., Jiang, M., Pei, R., Trippler, M., Broering, R., Bucchi, A., Sowa, J. P., Dittmer, U., Yang, D., et al. (2009). Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells. Hepatology 49, 1132-1140.
    • (2009) Hepatology , vol.49 , pp. 1132-1140
    • Wu, J.1    Meng, Z.2    Jiang, M.3    Pei, R.4    Trippler, M.5    Broering, R.6    Bucchi, A.7    Sowa, J.P.8    Dittmer, U.9    Yang, D.10
  • 46
    • 36749058339 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1
    • Wu, M., Xu, Y., Lin, S., Zhang, X., Xiang, L., and Yuan, Z. (2007). Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1. J Gen Virol 88, 3260-3269.
    • (2007) J Gen Virol , vol.88 , pp. 3260-3269
    • Wu, M.1    Xu, Y.2    Lin, S.3    Zhang, X.4    Xiang, L.5    Yuan, Z.6
  • 47
    • 77951708374 scopus 로고    scopus 로고
    • Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
    • Zeng, W., Sun, L., Jiang, X., Chen, X., Hou, F., Adhikari, A., Xu, M., and Chen, Z. J. (2010). Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 141, 315-330.
    • (2010) Cell , vol.141 , pp. 315-330
    • Zeng, W.1    Sun, L.2    Jiang, X.3    Chen, X.4    Hou, F.5    Adhikari, A.6    Xu, M.7    Chen, Z.J.8
  • 48
    • 70350004240 scopus 로고    scopus 로고
    • Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3
    • Zeng, W., Xu, M., Liu, S., Sun, L., and Chen, Z. J. (2009). Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol Cell 36, 315-325.
    • (2009) Mol Cell , vol.36 , pp. 315-325
    • Zeng, W.1    Xu, M.2    Liu, S.3    Sun, L.4    Chen, Z.J.5
  • 49
    • 34249058119 scopus 로고    scopus 로고
    • The NEMO adaptor bridges the nuclear factorkappaB and interferon regulatory factor signaling pathways
    • Zhao, T., Yang, L., Sun, Q., Arguello, M., Ballard, D. W., Hiscott, J., and Lin, R. (2007). The NEMO adaptor bridges the nuclear factorkappaB and interferon regulatory factor signaling pathways. Nat Immunol 8, 592-600.
    • (2007) Nat Immunol , vol.8 , pp. 592-600
    • Zhao, T.1    Yang, L.2    Sun, Q.3    Arguello, M.4    Ballard, D.W.5    Hiscott, J.6    Lin, R.7
  • 50
    • 55549102621 scopus 로고    scopus 로고
    • PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production
    • Zheng, D., Chen, G., Guo, B., Cheng, G., and Tang, H. (2008). PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production. Cell Res 18, 1105-1113.
    • (2008) Cell Res , vol.18 , pp. 1105-1113
    • Zheng, D.1    Chen, G.2    Guo, B.3    Cheng, G.4    Tang, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.