Hepatitis B virus X protein suppresses virus-triggered IRF3 activation and IFN-β induction by disrupting the VISA-associated complex

Cellular and Molecular Immunology

Volumn 7, Issue 5, 2010, Pages 341-348

  Wang, Xianmiao ^a   Li, Ying ^a   Mao, Aiping ^a   Li, Chao ^a   Li, Yongkui ^a   Tien, Po ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

HBx; innate immunity; signal transduction; type I interferons; VISA

Indexed keywords

BETA INTERFERON; GENE PRODUCT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEPATITIS B VIRUS X PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; PROTEIN; PROTEIN ISG15; PROTEIN KINASE; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TANK BINDING KINASE I; UNCLASSIFIED DRUG; VIRUS INDUCED SIGNALING ADAPTOR PROTEIN; TRANSACTIVATOR PROTEIN; VISA PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN BHK; CELL STRAIN HEK293; CONTROLLED STUDY; GENE OVEREXPRESSION; HEPATITIS B VIRUS; IMMUNOPRECIPITATION; INNATE IMMUNITY; LIVER CELL; NONHUMAN; PROTEIN INDUCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STOP CODON; SUPPRESSOR GENE; TRANSIENT TRANSFECTION; VIRUS CELL INTERACTION; ANIMAL; CELL LINE; GENETICS; HAMSTER; HUMAN; IMMUNOLOGY; METABOLISM; PROMOTER REGION; PROTEIN BINDING;

HEPATITIS B VIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CRICETINAE; HEPATITIS B VIRUS; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANS-ACTIVATORS;

EID: 77957679632     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2010.36     Document Type: Article

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