Cadmium induced p53-dependent activation of stress signaling, accumulation of ubiquitinated proteins, and apoptosis in mouse embryonic fibroblast cells

Toxicological Sciences

Volumn 120, Issue 2, 2011, Pages 403-412

  Yu, Xiaozhong ^a   Sidhu, Jaspreet S ^a,b   Hong, Sungwoo ^a   Robinson, Joshua F ^a,c   Ponce, Rafael A ^a,d   Faustman, Elaine M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Molecular Epidemiology Inc   (United States)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d AMGEN INC   (United States)

Author keywords

Apoptosis; Cadmium; Cell cycle arrest; p53; Stress signaling; Ubiquitination

Indexed keywords

CADMIUM; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; UBIQUITINATED PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; EMBRYO CELL; ENZYME PHOSPHORYLATION; FIBROBLAST; MOUSE; NONHUMAN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STRESS; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 79953111521     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr010     Document Type: Article

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