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Acknowledgments: We thank R. González-Amaro, D. Sancho, J. L. Rodríguez, and S. Bartlett for comments and critical reading of the manuscript. Funding: This work was supported by grant SAF2008-02719 from the Spanish Ministry of Science and Innovation (MICINN) to P.M. and grants SAF2008-02635 (MICINN) and INSINET 01592006 [Comunidad de Madrid (FONCICYTC002-2009-1ALA/127249)] and a MEICA award (Genoma España) to F.S.-M. P.M. holds a MICINN "Ramón y Cajal" contract (RYC-2006). The CNIC is supported by the MICINN and the Pro CNIC Foundation.
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