CD69 controls the pathogenesis of allergic airway inflammation

Journal of Immunology

Volumn 183, Issue 12, 2009, Pages 8203-8215

  Miki Hosokawa, Takako ^a   Hasegawa, Akihiro ^a,b   Iwamura, Chiaki ^a   Shinoda, Kenta ^a   Tofukuji, Soichi ^a   Watanabe, Yukiko ^a   Hosokawa, Hiroyuki ^a   Motohashi, Shinichiro ^a   Hashimoto, Kahoko ^c   Shirai, Mutsunori ^b   Yamashita, Masakatsu ^a   Nakayama, Toshinori ^a  

^a CHIBA UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; ALLERGEN; AUTACOID; LECTIN; LEUKOCYTE ANTIGEN; MONOCLONAL ANTIBODY; OVALBUMIN; T LYMPHOCYTE ANTIGEN;

ALLERGIC DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; ASTHMA; CELL INFILTRATION; CELL MIGRATION; CELL TRANSFER; CONTROLLED STUDY; MOUSE; MUCUS SECRETION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; BRONCHUS HYPERREACTIVITY; C57BL MOUSE; DISEASE MODEL; EOSINOPHIL; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT ALLERGY; TRANSGENIC MOUSE;

ALLERGENS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ASTHMA; BRONCHIAL HYPERREACTIVITY; DISEASE MODELS, ANIMAL; EOSINOPHILS; INFLAMMATION MEDIATORS; LECTINS, C-TYPE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OVALBUMIN; RESPIRATORY HYPERSENSITIVITY;

EID: 76249132174     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900646     Document Type: Article

References (38)

1. McFadden, E. R., Jr., and I. A. Gilbert. 1992. Asthma. N. Engl. J. Med. 327: 1928-1937.
2. Busse, W. W., and R. F. Lemanske, Jr. 2001. Asthma. N. Engl. J. Med. 344: 350-362.
3. Hamelmann, E., and E. W. Gelfand. 2001. IL-5-induced airway eosinophilia-the key to asthma? Immunol. Rev. 179: 182-191. (Pubitemid 32171285)
4. Lloyd, C. M., J. A. Gonzalo, A. J. Coyle, and J. C. Gutierrez-Ramos. 2001. Mouse models of allergic airway disease. Adv. Immunol. 77: 263-295. (Pubitemid 33703708)
5. Wills-Karp, M. 2004. Interleukin-13 in asthma pathogenesis. Immunol. Rev. 202: 175-190.
6. Cohn, L., J. A. Elias, and G. L. Chupp. 2004. Asthma: mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22: 789-815. (Pubitemid 38680442)
7. Umetsu, D. T., and R. H. DeKruyff. 2006. The regulation of allergy and asthma. Immunol. Rev. 212: 238-255.
8. Robinson, D. S., Q. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. M. Bentley, C. Corrigan, S. R. Durham, and A. B. Kay. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326: 298-304.
9. Corrigan, C. J., Q. Hamid, J. North, J. Barkans, R. Moqbel, S. Durham, V. Gemou-Engesaeth, and A. B. Kay. 1995. Peripheral blood CD4 but not CD8 T-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy. Am. J. Respir. Cell Mol. Biol. 12: 567-578.
10. Ziegler, S. F., F. Ramsdell, K. A. Hjerrild, R. J. Armitage, K. H. Grabstein, K. B. Hennen, T. Farrah, W. C. Fanslow, E. M. Shevach, and M. R. Alderson. 1993. Molecular characterization of the early activation antigen CD69: a type II membrane glycoprotein related to a family of natural killer cell activation antigens. Eur. J. Immunol. 23: 1643-1648.
11. Testi, R., D. D'Ambrosio, R. De Maria, and A. Santoni. 1994. The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. Immunol. Today 15: 479-483. (Pubitemid 24316014)
12. Sancho, D., M. Gomez, and F. Sanchez-Madrid. 2005. CD69 is an immunoregulatory molecule induced following activation. Trends Immunol. 26: 136-140. (Pubitemid 40312520)
13. Nakayama, T., D. J. Kasprowicz, M. Yamashita, L. A. Schubert, G. Gillard, M. Kimura, A. Didierlaurent, H. Koseki, and S. F. Ziegler. 2002. The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J. Immunol. 168: 87-94.
14. Feng, C., K. J. Woodside, B. A. Vance, D. El-Khoury, M. Canelles, J. Lee, R. Gress, B. J. Fowlkes, E. W. Shores, and P. E. Love. 2002. A potential role for CD69 in thymocyte emigration. Int. Immunol. 14: 535-544.
15. Sancho, D., M. Gomez, F. Viedma, E. Esplugues, M. Gordon-Alonso, M. A. Garcia-Lopez, H. de la Fuente, A. C. Martinez, P. Lauzurica, and F. Sanchez-Madrid. 2003. CD69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis. J. Clin. Invest. 112: 872-882.
16. Murata, K., M. Inami, A. Hasegawa, S. Kubo, M. Kimura, M. Yamashita, H. Hosokawa, T. Nagao, K. Suzuki, K. Hashimoto, et al. 2003. CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. Int. Immunol. 15: 987-992.
17. 1 and lymphocyte egress from lymphoid organs. Nature 440: 540-544.
18. Okabe, M., M. Ikawa, K. Kominami, T. Nakanishi, and Y. Nishimune. 1997. "Green mice" as a source of ubiquitous green cells. Federation Eur. Biochem. Soc. Lett. 407: 313-319.
19. low thymocytes in vivo. Science 250: 1720-1723.
20. + cells by CD4. Science 249: 1558-1561.
21. Yamashita, M., M. Kimura, M. Kubo, C. Shimizu, T. Tada, R. M. Perlmutter, and T. Nakayama. 1999. T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation. Proc. Natl. Acad. Sci. USA 96: 1024-1029.
22. Kamata, T., M. Yamashita, M. Kimura, K. Murata, M. Inami, C. Shimizu, K. Sugaya, C. R. Wang, M. Taniguchi, and T. Nakayama. 2003. src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation. J. Clin. Invest. 111: 109-119.
23. Myou, S., A. R. Leff, S. Myo, E. Boetticher, J. Tong, A. Y. Meliton, J. Liu, N. M. Munoz, and X. Zhu. 2003. Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT. J. Exp. Med. 198: 1573-1582.
24. Nigo, Y. I., M. Yamashita, K. Hirahara, R. Shinnakasu, M. Inami, M. Kimura, A. Hasegawa, Y. Kohno, and T. Nakayama. 2006. Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function. Proc. Natl. Acad. Sci. USA 103: 2286-2291.
25. Kimura, M. Y., H. Hosokawa, M. Yamashita, A. Hasegawa, C. Iwamura, H. Watarai, M. Taniguchi, T. Takagi, S. Ishii, and T. Nakayama. 2005. Regulation of T helper type 2 cell differentiation by murine Schnurri-2. J. Exp. Med. 201: 397-408.
26. Kang, H. S., S. E. Blink, R. K. Chin, Y. Lee, O. Kim, J. Weinstock, T. Waldschmidt, D. Conrad, B. Chen, J. Solway, A. I. Sperling, and Y. X. Fu. 2003. Lymphotoxin is required for maintaining physiological levels of serum IgE that minimizes Th1-mediated airway inflammation. J. Exp. Med. 198: 1643-1652.
27. Koya, T., T. Kodama, K. Takeda, N. Miyahara, E. S. Yang, C. Taube, A. Joetham, J. W. Park, A. Dakhama, and E. W. Gelfand. 2006. Importance of myeloid dendritic cells in persistent airway disease after repeated allergen exposure. Am. J. Respir Crit. Care Med. 173: 42-55.
28. Hirahara, K., M. Yamashita, C. Iwamura, K. Shinoda, A. Hasegawa, H. Yoshizawa, H. Koseki, F. Gejyo, and T. Nakayama. 2008. 2008. Repressor of GATA regulates TH2-driven allergic airway inflammation and airway hyperresponsiveness. J. Allergy Clin. Immunol. 122: 512-520.
29. Kimura, M., Y. Koseki, M. Yamashita, N. Watanabe, C. Shimizu, T. Katsumoto, T. Kitamura, M. Taniguchi, H. Koseki, and T. Nakayama. 2001. Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene. Immunity 15: 275-287.
30. Hasegawa, A., K. Hayashi, H. Kishimoto, M. Yang, S. Tofukuji, K. Suzuki, H. Nakajima, R. M. Hoffman, M. Shirai, and T. Nakayama. 2009. Color-coded real-time cellular imaging of T lymphocyte accumulation and focus formation in mouse asthma model. J. Allergy Clin. Immunol. In press.
31. Wands, J. M., C. L. Roark, M. K. Aydintug, N. Jin, Y. S. Hahn, L. Cook, X. Yin, J. Dal Porto, M. Lahn, D. M. Hyde, Born, et al. 2005. Distribution and leukocyte contacts of γδ T cells in the lung. J. Leukocyte Biol. 78: 1086-1096.
32. Nakajima, H., H. Sano, T. Nishimura, S. Yoshida, and I. Iwamoto. 1994. Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue. J. Exp. Med. 179: 1145-1154.
33. Kaminuma, O., H. Fujimura, K. Fushimi, A. Nakata, A. Sakai, S. Chishima, K. Ogawa, M. Kikuchi, H. Kikkawa, K. Akiyama, and A. Mori. 2001. Dynamics of antigen-specific helper T cells at the initiation of airway eosinophilic inflammation. Eur. J. Immunol. 31: 2669-2679.
34. Bochner, B. S., D. A. Klunk, S. A. Sterbinsky, R. L. Coffman, and R. P. Schleimer. 1995. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J. Immunol. 154: 799-803.
35. Sedgwick, J. B., K. J. Jansen, J. D. Kennedy, H. Kita, and W. W. Busse. 2005. Effects of the very late adhesion molecule 4 antagonist WAY103 on human peripheral blood eosinophil vascular cell adhesion molecule 1-dependent functions. J. Allergy Clin. Immunol. 116: 812-819.
36. Okigami, H., K. Takeshita, M. Tajimi, H. Komura, M. Albers, T. E. Lehmann, T. Rolle, and K. B. Bacon. 2007. Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)-4. Eur. J. Pharmacol. 559: 202-209.
37. Lauzurica, P., D. Sancho, M. Torres, B. Albella, M. Marazuela, T. Merino, J. A. Bueren, A. C. Martinez, and F. Sanchez-Madrid. 2000. Phenotypic and functional characteristics of hematopoietic cell lineages in CD69-deficient mice. Blood 95: 2312-2320.
38. Yokoyama, W. M., F. Koning, P. J. Kehn, G. M. Pereira, G. Stingl, J. E. Coligan, and E. M. Shevach. 1988. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J. Immunol. 141: 369-376.