CD69-null mice protected from arthritis induced with anti-type II collagen antibodies

International Immunology

Volumn 15, Issue 8, 2003, Pages 987-992

  Murata, Kaoru ^a   Inami, Masamichi ^a   Hasegawa, Akihiro ^a   Kubo, Shuichi ^a   Kimura, Motoko ^a   Yamashita, Masakatsu ^a   Hosokawa, Hiroyuki ^a   Nagao, Tomokazu ^b   Suzuki, Kazuo ^b   Hashimoto, Kahoko ^d   Shinkai, Hiroshi ^a   Koseki, Haruhiko ^a   Taniguchi, Masaru ^a   Ziegler, Steven F ^c   Nakayama, Toshinori ^a  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c BENAROYA RESEARCH INSTITUTE   (United States)

^d NONE

Author keywords

IL 6; Neutrophil; Rheumatoid arthritis

Indexed keywords

B LYMPHOCYTE ANTIGEN; CD69 ANTIGEN; CHEMOKINE; COLLAGEN ANTIBODY; COLLAGEN TYPE 2; CYTOKINE; T LYMPHOCYTE ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; ATTENUATION; CELL TRANSFER; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; GENE TARGETING; HISTOLOGY; IN SITU HYBRIDIZATION; INFLAMMATORY DISEASE; LEUKOCYTE ACTIVATION; LEUKOCYTE FUNCTION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; THROMBOCYTE ACTIVATION; WILD TYPE;

ADOPTIVE TRANSFER; ANIMALS; ANKLE JOINT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ARTHRITIS, EXPERIMENTAL; CHEMOKINES; COLLAGEN TYPE II; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; HINDLIMB; IN SITU HYBRIDIZATION; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIOGLYCOLATES;

EID: 12444265792     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg102     Document Type: Article

References (24)

1. Myers, L. K., Rosloniec, E. F., Cremer, M. A. and Kang, A. H. 1997. Collagen-induced arthritis, an animal model of autoimmunity. Life Sci. 61:1861.
2. Holmdahl, R., Bockermann, R., Backlund, J. and Yamada, H. 2002. The molecular pathogenesis of collagen-induced arthritis in mice - a model for rheumatoid arthritis. Ageing Res. Rev. 1:135.
3. Hirano, T. 2002. Revival of the autoantibody model in rheumatoid arthritis. Nat. Immunol. 3:342.
4. Matsumoto, I., Maccioni, M., Lee, D. M., Maurice, M., Simmons, B., Brenner, M., Mathis, D. and Benoist, C. 2002. How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease. Nat. Immunol. 3:360.
5. Wipke, B. T., Wang, Z., Kim, J., McCarthy, T. J. and Allen, P. M. 2002. Dynamic visualization of a joint-specific autoimmune response through positron emission tomography. Nat. Immunol. 3:366.
6. Terato, K., Hasty, K. A., Reife, R. A., Cremer, M. A., Kang, A. H. and Stuart, J. M. 1992, Induction of arthritis with monoclonal antibodies to collagen. J. Immunol. 148:2103.
7. Kagari, T., Doi, H. and Shimozato, T. 2002. The importance of IL-1β and TNF-α, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis. J. Immunol. 169:1459.
8. Johansson, A. C., Hansson, A. S., Nandakumar, K. S., Backlund, J. and Holmdahl, R. 2001. IL-10-deficient B10.Q mice develop more severe collagen-induced arthritis, but are protected from arthritis induced with anti-type II collagen antibodies. J. Immunol. 167:3505.
9. Ziegler, S. F., Ramsdell, F., Hjerrild, K. A., Armitage, R. J., Grabstein, K. H., Hennen, K. B., Farrah, T., Fanslow, W. C., Shevach, E. M. and Alderson, M. R. 1993. Molecular characterization of the early activation antigen CD69: a type II membrane glycoprotein related to a family of natural killer cell activation antigens. Eur. J. Immunol. 23:1643.
10. Testi, R., D'Ambrosio, D., De Maria, R. and Santoni, A. 1994. The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. Immunol. Today 15:479.
11. Yamashita, I., Nagata, T., Tada, T. and Nakayama, T. 1993. CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection. Int. Immunol. 5:1139.
12. Bendelac, A., Matzinger, P., Seder, R. A., Paul, W. E. and Schwartz, R. H. 1992. Activation events during thymic selection. J. Exp. Med. 175:731.
13. Nakayama, T., Kasprowicz, D. J., Yamashita, M., Schubert, L. A., Gillard, G., Kimura, M., Didierlaurent, A., Koseki, H. and Ziegler, S. F. 2002. The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J. Immunol. 168:87.
14. Feng, C., Woodside, K. J., Vance, B. A., El-Khoury, D., Canelles, M., Lee, J., Gress, R., Fowlkes, B. J., Shores, E. W. and Love, P. E. 2002. A potential role for CD69 in thymocyte emigration. Int. Immunol. 14:535.
15. Lauzurica, P., Sancho, D., Torres, M., Albella, B., Marazuela, M., Merino, T., Bueren, J. A., Martinez, A. C. and Sanchez-Madrid, F. 2000. Phenotypic and functional characteristics of hematopoietic cell lineages in CD69-deficient mice. Blood 95:2312.
16. McInnes, I. B., Leung, B. P., Sturrock, R. D., Field, M. and Liew, F. Y. 1997. Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis. Nat. Med. 3:189.
17. Ziegler, S. F., Levin, S. D., Johnson, L., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Baker, E., Sutherland, G. R., Feldhaus, A. L. and Ramsdell, F. 1994. The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J. Immunol. 152:1228.
18. h2 cell differentiation by mel-18, a mammalian polycomb group gene. Immunity 15:275.
19. Shibata, Y., Kamata, T., Kimura, M., Yamashita, M., Wang, C. R., Murata, K., Miyazaki, M., Taniguchi, M., Watanabe, N. and Nakayama, T. 2002. Ras activation in T cells determines the development of antigen-induced airway hyperresponsiveness and eosinophilic inflammation. J. Immunol. 169:2134.
20. Hoshino, M., Sone, M., Fukata, M., Kuroda, S., Kaibuchi, K., Nabeshima, Y. and Hama, C. 1999. Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1. J. Biol. Chem. 274:17837.
21. Ajuebor, M. N., Das, A. M., Virag, L., Flower, R. J., Szabo, C. and Perretti, M. 1999. Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J. Immunol. 162:1685.
22. Choy, E. H. and Panayi, G. S. 2001. Cytokine pathways and joint inflammation in rheumatoid arthritis. N. Engl. J. Med. 344:907.
23. Wipke, B. T. and Allen, P. M. 2001. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J. Immunol. 167:1601.
24. 4 and LFA-1 integrins in selectin-independent monocyte and neutrophil migration to joints of rats with adjuvant arthritis. Int. Immunol. 12:141.