RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins

Journal of Biological Chemistry

Volumn 286, Issue 5, 2011, Pages 3379-3386

  Jia, Lijun ^a,c   Bickel, Jeremy S ^b   Wu, Jiaxue ^b   Morgan, Meredith A ^a   Li, Hua ^a   Yang, Jie ^a   Yu, Xiaochun ^b   Chan, Raymond C ^b   Sun, Yi ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; DISEASES; DNA; GENES; MAMMALS;

CAENORHABDITIS ELEGANS; DNA DAMAGE RESPONSE; DNA DOUBLE STRAND BREAKS; E3 UBIQUITIN LIGASES; GENOMIC INTEGRITY; HUMAN CANCER CELLS; MAMMALIAN GENOMES; UBIQUITIN LIGASES;

PROTEINS;

CULLIN; RING BOX PROTEIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CDT1 PROTEIN, HUMAN; CELL CYCLE PROTEIN; ORIGIN RECOGNITION COMPLEX; RBX1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ANEUPLOIDY; ARTICLE; CAENORHABDITIS ELEGANS; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INTESTINE CELL; PRIORITY JOURNAL; ANIMAL; ANIMAL EMBRYO; GENETICS; GENOMIC INSTABILITY; HUMAN GENOME; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

CAENORHABDITIS ELEGANS; MAMMALIA;

ANIMALS; CAENORHABDITIS ELEGANS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DNA REPLICATION; EMBRYO, NONMAMMALIAN; GENE SILENCING; GENOME, HUMAN; GENOMIC INSTABILITY; HUMANS; ORIGIN RECOGNITION COMPLEX; UBIQUITIN-PROTEIN LIGASES;

EID: 79952787761     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.188425     Document Type: Article

References (53)

1. Deshaies, R. J., and Joazeiro, C. A. (2009) Annu. Rev. Biochem. 78, 399-434
2. Nakayama, K. I., and Nakayama, K. (2006) Nat. Rev. Cancer 6, 369-381
3. Yen, H. C., and Elledge, S. J. (2008) Science 322, 923-929
4. Soucy, T. A., Smith, P. G., Milhollen, M. A., Berger, A. J., Gavin, J. M., Adhikari, S., Brownell, J. E., Burke, K. E., Cardin, D. P., Critchley, S., Cullis, C. A., Doucette, A., Garnsey, J. J., Gaulin, J. L., Gershman, R. E., Lublinsky, A. R., McDonald, A., Mizutani, H., Narayanan, U., Olhava, E. J., Peluso, S., Rezaei, M., Sintchak, M. D., Talreja, T., Thomas, M. P., Traore, T., Vyskocil, S., Weatherhead, G. S., Yu, J., Zhang, J., Dick, L. R., Claiborne, C. F., Rolfe, M., Bolen, J. B., and Langston, S. P. (2009) Nature 458, 732-736
5. Nalepa, G., Rolfe, M., and Harper, J. W. (2006) Nat. Rev. Drug Discov. 5, 596-613
6. Petroski, M. D., and Deshaies, R. J. (2005) Nat. Rev. Mol. Cell Biol. 6, 9-20
7. Chen, A., Wu, K., Fuchs, S. Y., Tan, P., Gomez, C., and Pan, Z. Q. (2000) J. Biol. Chem. 275, 15432-15439
8. Kamura, T., Koepp, D. M., Conrad, M. N., Skowyra, D., Moreland, R. J., Iliopoulos, O., Lane, W. S., Kaelin, W. G., Jr, Elledge, S. J., Conaway, R. C., Harper, J. W., and Conaway, J. W. (1999) Science 284, 657-661
9. Ohta, T., Michel, J. J., Schottelius, A. J., and Xiong, Y. (1999) Mol. Cell 3, 535-541
10. Zheng, N., Schulman, B. A., Song, L., Miller, J. J., Jeffrey, P. D., Wang, P., Chu, C., Koepp, D. M., Elledge, S. J., Pagano, M., Conaway, R. C., Conaway, J. W., Harper, J. W., and Pavletich, N. P. (2002) Nature 416, 703-709
11. Ohta, T., Michel, J. J., and Xiong, Y. (1999) Oncogene 18, 6758-6766
12. Seol, J. H., Feldman, R. M., Zachariae, W., Shevchenko, A., Correll, C. C., Lyapina, S., Chi, Y., Galova, M., Claypool, J., Sandmeyer, S., Nasmyth, K., Deshaies, R. J., Shevchenko, A., and Deshaies, R. J. (1999) Genes Dev. 13, 1614-1626
13. Swaroop, M., Wang, Y., Miller, P., Duan, H., Jatkoe, T., Madore, S. J., and Sun, Y. (2000) Oncogene 19, 2855-2866
14. Moore, R., and Boyd, L. (2004) Genesis 38, 1-12
15. Sasagawa, Y., Urano, T., Kohara, Y., Takahashi, H., and Higashitani, A. (2003) Genes Cells 8, 857-872
16. Noureddine, M. A., Donaldson, T. D., Thacker, S. A., and Duronio, R. J. (2002) Dev. Cell 2, 757-770
17. Tan, M., Davis, S. W., Saunders, T. L., Zhu, Y., and Sun, Y. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 6203-6208
18. Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q., Li, M. Z., Zhao, Z., Smogorzewska, A., Sowa, M. E., Ang, X. L., Westbrook, T. F., Liang, A. C., Chang, K., Hackett, J. A., Harper, J. W., Hannon, G. J., and Elledge, S. J. (2008) Science 319, 620-624
19. Jia, L., Soengas, M. S., and Sun, Y. (2009) Cancer Res. 69, 4974-4982
20. Kamath, R. S., and Ahringer, J. (2003) Methods 30, 313-321
21. Bickel, J. S., Chen, L., Hayward, J., Yeap, S. L., Alkers, A. E., and Chan, R. C. (2010) PLoS Genet. 6, e1001028
22. Zhong, W., Feng, H., Santiago, F. E., and Kipreos, E. T. (2003) Nature 423, 885-889
23. Bhalla, N., Wynne, D. J., Jantsch, V., and Dernburg, A. F. (2008) PLoS Genet. 4, e1000235
24. Zheng, M., Morgan-Lappe, S. E., Yang, J., Bockbrader, K. M., Pamarthy, D., Thomas, D., Fesik, S. W., and Sun, Y. (2008) Cancer Res. 68, 7570-7578
25. Xu, B., Kim, St., and Kastan, M. B. (2001) Mol. Cell. Biol. 21, 3445-3450
26. Dai, Y., and Grant, S. (2010) Clin. Cancer Res. 16, 376-383
27. Blasina, A., Hallin, J., Chen, E., Arango, M. E., Kraynov, E., Register, J., Grant, S., Ninkovic, S., Chen, P., Nichols, T., O'Connor, P., and Anderes, K. (2008) Mol. Cancer Ther. 7, 2394-2404
28. Wilson, G. D. (2004) Cancer Metastasis Rev. 23, 209-225
29. Bartek, J., Bartkova, J., and Lukas, J. (2007) Oncogene 26, 7773-7779
30. Hook, S. S., Lin, J. J., and Dutta, A. (2007) Curr. Opin. Cell Biol. 19, 663-671
31. Liontos, M., Koutsami, M., Sideridou, M., Evangelou, K., Kletsas, D., Levy, B., Kotsinas, A., Nahum, O., Zoumpourlis, V., Kouloukoussa, M., Lygerou, Z., Taraviras, S., Kittas, C., Bartkova, J., Papavassiliou, A. G., Bartek, J., Halazonetis, T. D., and Gorgoulis, V. G. (2007) Cancer Res. 67, 10899-10909
32. Skaar, J. R., D'Angiolella, V., Pagan, J. K., and Pagano, M. (2009) Cell 137, 1358-1358e1
33. Li, X., Zhao, Q., Liao, R., Sun, P., and Wu, X. (2003) J. Biol. Chem. 278, 30854-30858
34. Méndez, J., Zou-Yang, X. H., Kim, S. Y., Hidaka, M., Tansey, W. P., and Stillman, B. (2002) Mol. Cell 9, 481-491
35. Hu, J., and Xiong, Y. (2006) J. Biol. Chem. 281, 3753-3756
36. Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K. I., Nakayama, K., Fujita, M., Lygerou, Z., and Nishimoto, T. (2006) EMBO J. 25, 1126-1136
37. Speck, C., Chen, Z., Li, H., and Stillman, B. (2005) Nat. Struct. Mol. Biol. 12, 965-971
38. Drury, L. S., Perkins, G., and Diffley, J. F. (2000) Curr. Biol. 10, 231-240
39. Perkins, G., Drury, L. S., and Diffley, J. F. (2001) EMBO J. 20, 4836-4845
40. Gartner, A., MacQueen, A. J., and Villeneuve, A. M. (2004) Methods Mol. Biol. 280, 257-274
41. Gao, M. X., Liao, E. H., Yu, B., Wang, Y., Zhen, M., and Derry, W. B. (2008) Cell Death Differ. 15, 1054-1062
42. Gartner, A., Milstein, S., Ahmed, S., Hodgkin, J., and Hengartner, M. O. (2000) Mol. Cell 5, 435-443
43. Hofmann, E. R., Milstein, S., Boulton, S. J., Ye, M., Hofmann, J. J., Stergiou, L., Gartner, A., Vidal, M., and Hengartner, M. O. (2002) Curr. Biol. 12, 1908-1918
44. Merlet, J., Burger, J., Tavernier, N., Richaudeau, B., Gomes, J. E., and Pintard, L. (2010) Development 137, 3857-3866
45. Starostina, N. G., Simpliciano, J. M., McGuirk, M. A., and Kipreos, E. T. (2010) Dev. Cell 19, 753-764
46. Hedgecock, E. M., and White, J. G. (1985) Dev. Biol. 107, 128-133
47. Jin, J., Arias, E. E., Chen, J., Harper, J. W., and Walter, J. C. (2006) Mol. Cell 23, 709-721
48. Arias, E. E., and Walter, J. C. (2007) Genes Dev. 21, 497-518
49. Dutta, A. (2007) Nat. Genet. 39, 10-11
50. Rialland, M., Sola, F., and Santocanale, C. (2002) J. Cell Sci. 115, 1435-1440
51. Bell, S. P. (2002) Genes Dev. 16, 659-672
52. Petropoulou, C., Kotantaki, P., Karamitros, D., and Taraviras, S. (2008) Front. Biosci. 13, 4485-4494
53. Mehrotra, S., Maqbool, S. B., Kolpakas, A., Murnen, K., and Calvi, B. R. (2008) Genes Dev. 22, 3158-3171