-
1
-
-
0030271387
-
NF-kappa B: Ten years after
-
Baeuerle PA, Baltimore D. 1996. NF-kappa B: Ten years after. Cell 87: 13-20.
-
(1996)
Cell
, vol.87
, pp. 13-20
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
2
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
Beg AA, Baltimore D. 1996. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274: 782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
3
-
-
0033790715
-
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
-
Bodmer JL, Holler N, Reynard S, Vinciguerra P, Schneider P, Juo P, Blenis J, Tschopp J. 2000. TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nat Cell Biol 2: 241-243.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 241-243
-
-
Bodmer, J.L.1
Holler, N.2
Reynard, S.3
Vinciguerra, P.4
Schneider, P.5
Juo, P.6
Blenis, J.7
Tschopp, J.8
-
4
-
-
0343765810
-
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB
-
Bork PM, Schmitz ML, Kuhnt M, Escher Heinrich M. 1997. Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB. FEBS Lett 402: 85-90.
-
(1997)
FEBS Lett
, vol.402
, pp. 85-90
-
-
Bork, P.M.1
Schmitz, M.L.2
Kuhnt, M.3
Escher Heinrich, M.4
-
6
-
-
68749089762
-
The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation
-
Carlisi D, Lauricella M, D'Anneo A, Emanuele S, Angileri L, Di Fazio P, Santulli A, Vento R, Tesoriere G. 2009. The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation. Eur J Cancer 45: 2425-2438.
-
(2009)
Eur J Cancer
, vol.45
, pp. 2425-2438
-
-
Carlisi, D.1
Lauricella, M.2
D'Anneo, A.3
Emanuele, S.4
Angileri, L.5
Di Fazio, P.6
Santulli, A.7
Vento, R.8
Tesoriere, G.9
-
7
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, Ciliberto G, Moscinski L, Fernández-Luna JL, Nuñez G, Dalton WS, Jove R. 1999. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10: 105-115.
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
Turkson, J.4
Levitzki, A.5
Savino, R.6
Ciliberto, G.7
Moscinski, L.8
Fernández-Luna, J.L.9
Nuñez, G.10
Dalton, W.S.11
Jove, R.12
-
8
-
-
66449131460
-
Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway
-
Chen KF, Yeh PY, Hsu C, Hsu CH, Lu YS, Hsieh HP, Chen PJ, Cheng AL. 2009. Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem 284: 11121-11133.
-
(2009)
J Biol Chem
, vol.284
, pp. 11121-11133
-
-
Chen, K.F.1
Yeh, P.Y.2
Hsu, C.3
Hsu, C.H.4
Lu, Y.S.5
Hsieh, H.P.6
Chen, P.J.7
Cheng, A.L.8
-
9
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou TC, Talalay P. 1984. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22: 27-55.
-
(1984)
Adv Enzyme Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
10
-
-
49749146742
-
Differential responsiveness of human hepatoma cells versus normal hepatocytes to TRAIL in combination with either histone deacetylase inhibitors or conventional cytostatics
-
Dzieran J, Beck JF, Sonnemann J. 2008. Differential responsiveness of human hepatoma cells versus normal hepatocytes to TRAIL in combination with either histone deacetylase inhibitors or conventional cytostatics. Cancer Sci 99: 1685-1692.
-
(2008)
Cancer Sci
, vol.99
, pp. 1685-1692
-
-
Dzieran, J.1
Beck, J.F.2
Sonnemann, J.3
-
11
-
-
34249993174
-
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib
-
Emanuele S, Lauricella M, Carlisi D, Vassallo B, D'Anneo A, Di Fazio P, Vento R, Tesoriere G. 2007. SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. Apoptosis 12: 1327-1338.
-
(2007)
Apoptosis
, vol.12
, pp. 1327-1338
-
-
Emanuele, S.1
Lauricella, M.2
Carlisi, D.3
Vassallo, B.4
D'Anneo, A.5
Di Fazio, P.6
Vento, R.7
Tesoriere, G.8
-
12
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery JG, McDonnell P, Burke MB, Deen KC, Lyn S, Silverman C, Dul E, Appelbaum ER, Eichman C, DiPrinzio R, Dodds RA, James IE, Rosenberg M, Lee JC, Young PR. 1998. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 273: 14363-14367.
-
(1998)
J Biol Chem
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
Dul, E.7
Appelbaum, E.R.8
Eichman, C.9
DiPrinzio, R.10
Dodds, R.A.11
James, I.E.12
Rosenberg, M.13
Lee, J.C.14
Young, P.R.15
-
13
-
-
4344607589
-
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs
-
Ganten TM, Haas TL, Sykora J, Stahl H, Sprick MR, Fas SC, Krueger A, Weigand MA, Grosse-Wilde A, Stremmel W, Krammer PH, Walczak H. 2004. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ 11: S86-S96.
-
(2004)
Cell Death Differ
, vol.11
-
-
Ganten, T.M.1
Haas, T.L.2
Sykora, J.3
Stahl, H.4
Sprick, M.R.5
Fas, S.C.6
Krueger, A.7
Weigand, M.A.8
Grosse-Wilde, A.9
Stremmel, W.10
Krammer, P.H.11
Walczak, H.12
-
14
-
-
24344455107
-
Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo
-
Gao L, Zhang L, Hu J, Li F, Shao Y, Zhao D, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ. 2005. Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo. Clin Cancer Res 11: 6333-6341.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6333-6341
-
-
Gao, L.1
Zhang, L.2
Hu, J.3
Li, F.4
Shao, Y.5
Zhao, D.6
Kalvakolanu, D.V.7
Kopecko, D.J.8
Zhao, X.9
Xu, D.Q.10
-
15
-
-
0033230594
-
The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells
-
Giuliano M, Lauricella M, Calvaruso G, Carabillò M, Emanuele S, Vento R, Tesoriere G. 1999. The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells. Cancer Res 59: 5586-5595.
-
(1999)
Cancer Res
, vol.59
, pp. 5586-5595
-
-
Giuliano, M.1
Lauricella, M.2
Calvaruso, G.3
Carabillò, M.4
Emanuele, S.5
Vento, R.6
Tesoriere, G.7
-
16
-
-
66449097674
-
Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions
-
Gopal YN, Chanchorn E, Van Dyke MW. 2009. Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions. Mol Cancer Ther 8: 552-562.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 552-562
-
-
Gopal, Y.N.1
Chanchorn, E.2
Van Dyke, M.W.3
-
17
-
-
16844363378
-
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
-
Guzman ML, Rossi RM, Karnischky L, Li X, Peterson DR, Howard DS, Jordan CT. 2005. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 105: 4163-4169.
-
(2005)
Blood
, vol.105
, pp. 4163-4169
-
-
Guzman, M.L.1
Rossi, R.M.2
Karnischky, L.3
Li, X.4
Peterson, D.R.5
Howard, D.S.6
Jordan, C.T.7
-
18
-
-
0031915368
-
Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta
-
Hehner SP, Heinrich M, Bork PM, Vogt M, Ratter F, Lehmann V, Schulze-Osthoff K, Dröge W, Schmitz ML. 1998. Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta. J Biol Chem 273: 1288-1297.
-
(1998)
J Biol Chem
, vol.273
, pp. 1288-1297
-
-
Hehner, S.P.1
Heinrich, M.2
Bork, P.M.3
Vogt, M.4
Ratter, F.5
Lehmann, V.6
Schulze-Osthoff, K.7
Dröge, W.8
Schmitz, M.L.9
-
19
-
-
0030046753
-
STATs: Signal transducers and activators of transcription
-
Ihle JN. 1996. STATs: Signal transducers and activators of transcription. Cell 84: 331-334.
-
(1996)
Cell
, vol.84
, pp. 331-334
-
-
Ihle, J.N.1
-
20
-
-
65949119339
-
Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells
-
Ivanov VN, Zhou H, Partridge MA, Hei TK. 2009. Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells. Cancer Res 69: 3510-3519.
-
(2009)
Cancer Res
, vol.69
, pp. 3510-3519
-
-
Ivanov, V.N.1
Zhou, H.2
Partridge, M.A.3
Hei, T.K.4
-
21
-
-
22244449287
-
Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis
-
Jong-Hyun K, Lan L, Seung-Ok L, Yong-Tae K, Kyung-Ran Y, Dae-Ghon K. 2005. Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis. Cancer Res 65: 6312-6320.
-
(2005)
Cancer Res
, vol.65
, pp. 6312-6320
-
-
Jong-Hyun, K.1
Lan, L.2
Seung-Ok, L.3
Yong-Tae, K.4
Kyung-Ran, Y.5
Dae-Ghon, K.6
-
22
-
-
65549140597
-
Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach
-
Kawasaki BT, Hurt EM, Kalathur M, Duhagon MA, Milner JA, Kim YS, Farrar WL. 2009. Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach. Prostate 69: 827-837.
-
(2009)
Prostate
, vol.69
, pp. 827-837
-
-
Kawasaki, B.T.1
Hurt, E.M.2
Kalathur, M.3
Duhagon, M.A.4
Milner, J.A.5
Kim, Y.S.6
Farrar, W.L.7
-
23
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C. 2007. Mitochondrial membrane permeabilization in cell death. Physiol Rev 87: 99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
24
-
-
0035827569
-
Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 deathinducing signaling complex
-
Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S. 2001. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 deathinducing signaling complex. J Biol Chem 276: 20633-20640.
-
(2001)
J Biol Chem
, vol.276
, pp. 20633-20640
-
-
Krueger, A.1
Schmitz, I.2
Baumann, S.3
Krammer, P.H.4
Kirchhoff, S.5
-
25
-
-
65549120715
-
Modes of p53 regulation
-
Kruse JP, Gu W. 2009. Modes of p53 regulation. Cell 137: 609-622.
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
26
-
-
34347374690
-
Evidence that IL-6-type cytokine signaling in cardiomyocytes is inhibited by oxidative stress: Parthenolide targets JAK1 activation by generating ROS
-
Kurdi M, Booz GW. 2007. Evidence that IL-6-type cytokine signaling in cardiomyocytes is inhibited by oxidative stress: Parthenolide targets JAK1 activation by generating ROS. J Cell Physiol 212: 424-431.
-
(2007)
J Cell Physiol
, vol.212
, pp. 424-431
-
-
Kurdi, M.1
Booz, G.W.2
-
27
-
-
34548260509
-
Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis
-
Kusaba M, Nakao K, Goto T, Nishimura D, Kawashimo H, Shibata H, Motoyoshi Y, Taura N, Ichikawa T, Hamasaki K, Eguchi K. 2007. Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis. J Hepatol 47: 546-555.
-
(2007)
J Hepatol
, vol.47
, pp. 546-555
-
-
Kusaba, M.1
Nakao, K.2
Goto, T.3
Nishimura, D.4
Kawashimo, H.5
Shibata, H.6
Motoyoshi, Y.7
Taura, N.8
Ichikawa, T.9
Hamasaki, K.10
Eguchi, K.11
-
28
-
-
75749144323
-
Parthenolide, a sesquiterpene lactone from the medical herb fever few, shows anticancer activity against human melanoma cells in vitro
-
Lesiak K, Koprowska K, Zalesna I, Nejc D, Düchler M, Czyz M. 2009. Parthenolide, a sesquiterpene lactone from the medical herb fever few, shows anticancer activity against human melanoma cells in vitro. Melanoma Res 20: 21-34.
-
(2009)
Melanoma Res
, vol.20
, pp. 21-34
-
-
Lesiak, K.1
Koprowska, K.2
Zalesna, I.3
Nejc, D.4
Düchler, M.5
Czyz, M.6
-
29
-
-
16844368861
-
Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice
-
Ling X, Arlinghaus RB. 2005. Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice. Cancer Res 65: 2532-2536.
-
(2005)
Cancer Res
, vol.65
, pp. 2532-2536
-
-
Ling, X.1
Arlinghaus, R.B.2
-
30
-
-
3442884825
-
p53 upregulates death receptor 4 expression through an intronic p53 binding site
-
Liu X, Yue P, Khuri FR, Sun SY. 2004. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Res 64: 5078-5083.
-
(2004)
Cancer Res
, vol.64
, pp. 5078-5083
-
-
Liu, X.1
Yue, P.2
Khuri, F.R.3
Sun, S.Y.4
-
31
-
-
17144377494
-
Dual role of the anti-inflammatory sesquiterpene lactone: Regulation of life and death by parthenolide
-
Li-Weber M, Palfi K, Giaisi M, Krammer PH. 2005. Dual role of the anti-inflammatory sesquiterpene lactone: Regulation of life and death by parthenolide. Cell Death Differ 12: 408-409.
-
(2005)
Cell Death Differ
, vol.12
, pp. 408-409
-
-
Li-Weber, M.1
Palfi, K.2
Giaisi, M.3
Krammer, P.H.4
-
32
-
-
0030770614
-
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
-
MacFarlane M, Ahmad M, Srinivasula SM, Fernandes-Alnemri T, Cohen GM, Alnemri ES. 1997. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J Biol Chem 272: 25417-25420.
-
(1997)
J Biol Chem
, vol.272
, pp. 25417-25420
-
-
MacFarlane, M.1
Ahmad, M.2
Srinivasula, S.M.3
Fernandes-Alnemri, T.4
Cohen, G.M.5
Alnemri, E.S.6
-
33
-
-
70349438994
-
Tumour suppression by p53: A role for the DNA damage response?
-
Meek DW. 2009. Tumour suppression by p53: A role for the DNA damage response? Nat Rev Cancer 9: 714-723.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 714-723
-
-
Meek, D.W.1
-
35
-
-
6044240634
-
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
-
Nakshatri H, Rice SE, Bhat-Nakshatri P. 2004. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 23: 7330-7344.
-
(2004)
Oncogene
, vol.23
, pp. 7330-7344
-
-
Nakshatri, H.1
Rice, S.E.2
Bhat-Nakshatri, P.3
-
36
-
-
0032718891
-
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
-
Niu G, Heller R, Catlett-Falcone R, Coppola D, Jaroszeski M, Dalton W, Jove R, Yu H. 1999. Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res 59: 5059-5063.
-
(1999)
Cancer Res
, vol.59
, pp. 5059-5063
-
-
Niu, G.1
Heller, R.2
Catlett-Falcone, R.3
Coppola, D.4
Jaroszeski, M.5
Dalton, W.6
Jove, R.7
Yu, H.8
-
37
-
-
48449083208
-
Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells
-
Pajak B, Gajkowska B, Orzechowski A. 2008. Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells: Folia Histochem Cytobiol 46: 129-135.
-
(2008)
Folia Histochem Cytobiol
, vol.46
, pp. 129-135
-
-
Pajak, B.1
Gajkowska, B.2
Orzechowski, A.3
-
38
-
-
33947174342
-
Sensitivity and resistance of human cancer cells to TRAIL: Mechanisms and therapeutical perspectives
-
Pasquini L, Petrucci E, Riccioni R, Petronelli A, Testa U. 2006. Sensitivity and resistance of human cancer cells to TRAIL: Mechanisms and therapeutical perspectives. Cancer Ther 4: 47-72.
-
(2006)
Cancer Ther
, vol.4
, pp. 47-72
-
-
Pasquini, L.1
Petrucci, E.2
Riccioni, R.3
Petronelli, A.4
Testa, U.5
-
39
-
-
77951043153
-
The synthetic cannabinoid WIN sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by activating CHOP/DR5 axis
-
Pellerito O, Portanova P, De Blasio A, Santulli A, Vento R, Calvaruso G, Tesoriere G, Giuliano M. 2010. The synthetic cannabinoid WIN sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by activating CHOP/DR5 axis. Mol Pharmacol 77: 854-863.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 854-863
-
-
Pellerito, O.1
Portanova, P.2
De Blasio, A.3
Santulli, A.4
Vento, R.5
Calvaruso, G.6
Tesoriere, G.7
Giuliano, M.8
-
40
-
-
33644876853
-
Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy
-
Schuchmann M, Schulze-Bergkamen H, Fleischer B, Schattenberg JM, Siebler J, Weinmann A, Teufel A, Wörns M, Fischer T, Strand S, Lohse AW, Galle PR. 2006. Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy. Oncol Rep 15: 227-230.
-
(2006)
Oncol Rep
, vol.15
, pp. 227-230
-
-
Schuchmann, M.1
Schulze-Bergkamen, H.2
Fleischer, B.3
Schattenberg, J.M.4
Siebler, J.5
Weinmann, A.6
Teufel, A.7
Wörns, M.8
Fischer, T.9
Strand, S.10
Lohse, A.W.11
Galle, P.R.12
-
41
-
-
33749068887
-
Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model
-
Shanmugam R, Jayaprakasan V, Gokmen-Polar Y, Kelich S, Miller KD, Yip-Schneider M, Cheng L, Bhat-Nakshatri P, Sledge GW, Jr., Nakshatri H, Zheng QH, Miller MA, DeGrado T, Hutchins GD, Sweeney CJ. 2006. Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model. Prostate 66: 1498-1511.
-
(2006)
Prostate
, vol.66
, pp. 1498-1511
-
-
Shanmugam, R.1
Jayaprakasan, V.2
Gokmen-Polar, Y.3
Kelich, S.4
Miller, K.D.5
Yip-Schneider, M.6
Cheng, L.7
Bhat-Nakshatri, P.8
Sledge Jr, G.W.9
Nakshatri, H.10
Zheng, Q.H.11
Miller, M.A.12
DeGrado, T.13
Hutchins, G.D.14
Sweeney, C.J.15
-
42
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, Ramakrishnan L, Gray CL, Baker K, Wood WI, Goddard AD, Godowski P, Ashkenazi A. 1997. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277: 818-821.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
Ramakrishnan, L.7
Gray, C.L.8
Baker, K.9
Wood, W.I.10
Goddard, A.D.11
Godowski, P.12
Ashkenazi, A.13
-
43
-
-
0037204818
-
Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin
-
Shin EC, Seong YR, Kim CH, Kim H, Ahn YS, Kim K, Kim SJ, Hong SS, Park JH. 2002. Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. Exp Mol Med 34: 114-122.
-
(2002)
Exp Mol Med
, vol.34
, pp. 114-122
-
-
Shin, E.C.1
Seong, Y.R.2
Kim, C.H.3
Kim, H.4
Ahn, Y.S.5
Kim, K.6
Kim, S.J.7
Hong, S.S.8
Park, J.H.9
-
44
-
-
0034614643
-
Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family
-
Sobota R, Szwed M, Kasza A, Bugno M, Kordula T. 2000. Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family. Biochem Biophys Res Commun 267: 329-333.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 329-333
-
-
Sobota, R.1
Szwed, M.2
Kasza, A.3
Bugno, M.4
Kordula, T.5
-
45
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H. 2000. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12: 599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
Krammer, P.H.7
Walczak, H.8
-
46
-
-
41549113466
-
Antimyeloma effects of a sesquiterpene lactone parthenolide
-
Suvannasankha A, Crean CD, Shanmugam R, Farag SS, Abonour R, Boswell HS, Nakshatri H. 2008. Antimyeloma effects of a sesquiterpene lactone parthenolide. Clin Cancer Res 14: 1814-1822.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1814-1822
-
-
Suvannasankha, A.1
Crean, C.D.2
Shanmugam, R.3
Farag, S.S.4
Abonour, R.5
Boswell, H.S.6
Nakshatri, H.7
-
47
-
-
0034732258
-
Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
-
Takimoto R, El-Deiry WS. 2000. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene 19: 1735-1743.
-
(2000)
Oncogene
, vol.19
, pp. 1735-1743
-
-
Takimoto, R.1
El-Deiry, W.S.2
-
48
-
-
0028986193
-
NF-kappa B: A lesson in family values
-
Thanos D, Maniatis T. 1995. NF-kappa B: A lesson in family values. Cell 80: 529-532.
-
(1995)
Cell
, vol.80
, pp. 529-532
-
-
Thanos, D.1
Maniatis, T.2
-
49
-
-
0035399893
-
Biochemistry and function of the DISC
-
Walczak H, Sprick MR. 2001. Biochemistry and function of the DISC. Trends Biochem Sci 26: 452-453.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 452-453
-
-
Walczak, H.1
Sprick, M.R.2
-
50
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T, Smith C, Smolak P, Goodwin RG, Rauch CT, Schuh JC, Lynch DH. 1999. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5: 157-163.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
Chin, W.7
Jones, J.8
Woodward, A.9
Le, T.10
Smith, C.11
Smolak, P.12
Goodwin, R.G.13
Rauch, C.T.14
Schuh, J.C.15
Lynch, D.H.16
-
51
-
-
0037064130
-
Oxidative stress-mediated apoptosis
-
Wen J, You K, Lee S, Song C, Kim D. 2002. Oxidative stress-mediated apoptosis. J Biol Chem 277: 38954-38964.
-
(2002)
J Biol Chem
, vol.277
, pp. 38954-38964
-
-
Wen, J.1
You, K.2
Lee, S.3
Song, C.4
Kim, D.5
-
52
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA. 1995. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3: 673-682.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
Sutherland, G.R.7
Smith, T.D.8
Rauch, C.9
Smith, C.A.10
-
53
-
-
52949127317
-
The JAK kinases: Not just another kinase drug discovery target
-
Wilks AF. 2008. The JAK kinases: Not just another kinase drug discovery target. Semin Cell Dev Biol 19: 319-328.
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 319-328
-
-
Wilks, A.F.1
-
54
-
-
0033839749
-
Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines
-
Yamanaka T, Shiraki K, Sugimoto K, Ito T, Fujikawa K, Ito M, Takase K, Moriyama M, Nakano T, Suzuki A. 2000. Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 32: 482-490.
-
(2000)
Hepatology
, vol.32
, pp. 482-490
-
-
Yamanaka, T.1
Shiraki, K.2
Sugimoto, K.3
Ito, T.4
Fujikawa, K.5
Ito, M.6
Takase, K.7
Moriyama, M.8
Nakano, T.9
Suzuki, A.10
-
55
-
-
9744254768
-
Evaluation of combination chemotherapy: Integration of nonlinear regression, curve shift, isobologram, and combination index analyses
-
Zhao L, Wientjes MG, Au JL. 2004. Evaluation of combination chemotherapy: Integration of nonlinear regression, curve shift, isobologram, and combination index analyses. Clin Cancer Res 10: 7994-8004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7994-8004
-
-
Zhao, L.1
Wientjes, M.G.2
Au, J.L.3
|