-
1
-
-
55549129245
-
Progress and prospects: Zinc-finger nucleases as gene therapy agents
-
Carroll, D. (2008) Progress and prospects: Zinc-finger nucleases as gene therapy agents. Gene Ther. 15, 1463-1468.
-
(2008)
Gene Ther.
, vol.15
, pp. 1463-1468
-
-
Carroll, D.1
-
2
-
-
45749145124
-
Zinc-finger nucleases: The next generation emerges
-
Cathomen, T. and Joung, J.K. (2008) Zinc-finger nucleases: The next generation emerges. Mol Ther. 16, 1200-1207.
-
(2008)
Mol Ther.
, vol.16
, pp. 1200-1207
-
-
Cathomen, T.1
Joung, J.K.2
-
3
-
-
0035902445
-
Manipulating the mammalian genome by homologous recombination
-
Vasquez, K.M., Marburger, K., Intody, Z., and Wilson, J.H. (2001) Manipulating the mammalian genome by homologous recombination. Proc Natl Acad Sci USA. 98, 8403-8410.
-
(2001)
Proc Natl Acad Sci USA.
, vol.98
, pp. 8403-8410
-
-
Vasquez, K.M.1
Marburger, K.2
Intody, Z.3
Wilson, J.H.4
-
4
-
-
47349097567
-
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification
-
Maeder, M.L., Thibodeau-Beganny, S., Osiak, A., Wright, D.A., Anthony, R.M., Eichtinger, M., Jiang, T., Foley, J.E., Winfrey, R.J., Townsend, J.A., Unger-Wallace, E., Sander, J.D., Muller-Lerch, F., Fu, F., Pearlberg, J., Gobel, C., Dassie, J.P., Pruett-Miller, S.M., Porteus, M.H., Sgroi, D.C., Iafrate, A.J., Dobbs, D., McCray, P.B., Jr., Cathomen, T., Voytas, D.F., and Joung, J.K. (2008) Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell. 31, 294-301.
-
(2008)
Mol Cell.
, vol.31
, pp. 294-301
-
-
Maeder, M.L.1
Thibodeau-Beganny, S.2
Osiak, A.3
Wright, D.A.4
Anthony, R.M.5
Eichtinger, M.6
Jiang, T.7
Foley, J.E.8
Winfrey, R.J.9
Townsend, J.A.10
Unger-Wallace, E.11
Sander, J.D.12
Muller-Lerch, F.13
Fu, F.14
Pearlberg, J.15
Gobel, C.16
Dassie, J.P.17
Pruett-Miller, S.M.18
Porteus, M.H.19
Sgroi, D.C.20
Iafrate, A.J.21
Dobbs, D.22
McCray Jr., P.B.23
Cathomen, T.24
Voytas, D.F.25
Joung, J.K.26
more..
-
5
-
-
35948946526
-
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
-
Lombardo, A., Genovese, P., Beausejour, C.M., Colleoni, S., Lee, Y.L., Kim, K.A., Ando, D., Urnov, F.D., Galli, C., Gregory, P.D., Holmes, M.C., and Naldini, L. (2007) Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery. Nat Biotechnol. 25, 1298-1306.
-
(2007)
Nat Biotechnol.
, vol.25
, pp. 1298-1306
-
-
Lombardo, A.1
Genovese, P.2
Beausejour, C.M.3
Colleoni, S.4
Lee, Y.L.5
Kim, K.A.6
Ando, D.7
Urnov, F.D.8
Galli, C.9
Gregory, P.D.10
Holmes, M.C.11
Naldini, L.12
-
6
-
-
46949095221
-
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
-
Perez, E.E., Wang, J., Miller, J.C., Jouvenot, Y., Kim, K.A., Liu, O., Wang, N., Lee, G., Bartsevich, V.V., Lee, Y.L., Guschin, D.Y., Rupniewski, I., Waite, A.J., Carpenito, C., Carroll, R.G., Orange, J.S., Urnov, F.D., Rebar, E.J., Ando, D., Gregory, P.D., Riley, J.L., Holmes, M.C., and June, C.H. (2008) Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat Biotechnol. 26, 808-816.
-
(2008)
Nat Biotechnol.
, vol.26
, pp. 808-816
-
-
Perez, E.E.1
Wang, J.2
Miller, J.C.3
Jouvenot, Y.4
Kim, K.A.5
Liu, O.6
Wang, N.7
Lee, G.8
Bartsevich, V.V.9
Lee, Y.L.10
Guschin, D.Y.11
Rupniewski, I.12
Waite, A.J.13
Carpenito, C.14
Carroll, R.G.15
Orange, J.S.16
Urnov, F.D.17
Rebar, E.J.18
Ando, D.19
Gregory, P.D.20
Riley, J.L.21
Holmes, M.C.22
June, C.H.23
more..
-
7
-
-
44949155482
-
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
-
Doyon, Y., McCammon, J.M., Miller, J.C., Faraji, F., Ngo, C., Katibah, G.E., Amora, R., Hocking, T.D., Zhang, L., Rebar, E.J., Gregory, P.D., Urnov, F.D., and Amacher, S.L. (2008) Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat Biotechnol. 26, 702-708.
-
(2008)
Nat Biotechnol.
, vol.26
, pp. 702-708
-
-
Doyon, Y.1
McCammon, J.M.2
Miller, J.C.3
Faraji, F.4
Ngo, C.5
Katibah, G.E.6
Amora, R.7
Hocking, T.D.8
Zhang, L.9
Rebar, E.J.10
Gregory, P.D.11
Urnov, F.D.12
Amacher, S.L.13
-
8
-
-
84861409753
-
Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN)
-
Foley, J.E., Yeh, J.R., Maeder, M.L., Reyon, D., Sander, J.D., Peterson, R.T., and Joung, J.K. (2009) Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN). PLoS One. 4, e4348.
-
(2009)
PLoS One.
, vol.4
-
-
Foley, J.E.1
Yeh, J.R.2
Maeder, M.L.3
Reyon, D.4
Sander, J.D.5
Peterson, R.T.6
Joung, J.K.7
-
9
-
-
44949162060
-
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
-
Meng, X., Noyes, M.B., Zhu, L.J., Lawson, N.D., and Wolfe, S.A. (2008) Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat Biotechnol. 26, 695-701.
-
(2008)
Nat Biotechnol.
, vol.26
, pp. 695-701
-
-
Meng, X.1
Noyes, M.B.2
Zhu, L.J.3
Lawson, N.D.4
Wolfe, S.A.5
-
10
-
-
33750804666
-
Induction and repair of zinc-finger nuclease-targeted doublestrand breaks in Caenorhabditis elegans somatic cells
-
Morton, J., Davis, M.W., Jorgensen, E.M., and Carroll, D. (2006) Induction and repair of zinc-finger nuclease-targeted doublestrand breaks in Caenorhabditis elegans somatic cells. Proc Natl Acad Sci USA. 103, 16370-16375.
-
(2006)
Proc Natl Acad Sci USA.
, vol.103
, pp. 16370-16375
-
-
Morton, J.1
Davis, M.W.2
Jorgensen, E.M.3
Carroll, D.4
-
11
-
-
0037510038
-
Enhancing gene targeting with designed zinc finger nucleases
-
Bibikova, M., Beumer, K., Trautman, J.K., and Carroll, D. (2003) Enhancing gene targeting with designed zinc finger nucleases. Science. 300, 764.
-
(2003)
Science.
, vol.300
, pp. 764
-
-
Bibikova, M.1
Beumer, K.2
Trautman, J.K.3
Carroll, D.4
-
12
-
-
0030032063
-
Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain
-
Kim, Y.G., Cha, J., and Chandrasegaran, S. (1996) Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain. Proc Natl Acad Sci USA. 93, 1156-1160.
-
(1996)
Proc Natl Acad Sci USA.
, vol.93
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
13
-
-
0030587774
-
Zif268 protein-DNA complex refined at 1.6 A: A model system for understanding zinc finger-DNA interactions
-
Elrod-Erickson, M., Rould, M.A., Nekludova, L., and Pabo, C.O. (1996) Zif268 protein-DNA complex refined at 1.6 A: A model system for understanding zinc finger-DNA interactions. Structure. 4, 1171-1180.
-
(1996)
Structure.
, vol.4
, pp. 1171-1180
-
-
Elrod-Erickson, M.1
Rould, M.A.2
Nekludova, L.3
Pabo, C.O.4
-
14
-
-
0025773296
-
Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 A
-
Pavletich, N.P. and Pabo, C.O. (1991) Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 A. Science. 252, 809-817.
-
(1991)
Science.
, vol.252
, pp. 809-817
-
-
Pavletich, N.P.1
Pabo, C.O.2
-
15
-
-
0034602243
-
Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains
-
Dreier, B., Segal, D.J., and Barbas, C.F., 3rd (2000) Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains. J Mol Biol. 303, 489-502.
-
(2000)
J Mol Biol.
, vol.303
, pp. 489-502
-
-
Dreier, B.1
Segal, D.J.2
Barbas III, C.F.3
-
16
-
-
0036168937
-
Engineering polydactyl zinc-finger transcription factors
-
Beerli, R.R. and Barbas, C.F., 3rd (2002) Engineering polydactyl zinc-finger transcription factors. Nat Biotechnol. 20, 135-141.
-
(2002)
Nat Biotechnol.
, vol.20
, pp. 135-141
-
-
Beerli, R.R.1
Barbas III, C.F.2
-
17
-
-
0034749283
-
Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
-
Bibikova, M., Carroll, D., Segal, D.J., Trautman, J.K., Smith, J., Kim, Y.G., and Chandrasegaran, S. (2001) Stimulation of homologous recombination through targeted cleavage by chimeric nucleases. Mol Cell Biol. 21, 289-297.
-
(2001)
Mol Cell Biol.
, vol.21
, pp. 289-297
-
-
Bibikova, M.1
Carroll, D.2
Segal, D.J.3
Trautman, J.K.4
Smith, J.5
Kim, Y.G.6
Chandrasegaran, S.7
-
18
-
-
0034283804
-
Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains
-
Smith, J., Bibikova, M., Whitby, F.G., Reddy, A.R., Chandrasegaran, S., and Carroll, D. (2000) Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. Nucleic Acids Res. 28, 3361-3369.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3361-3369
-
-
Smith, J.1
Bibikova, M.2
Whitby, F.G.3
Reddy, A.R.4
Chandrasegaran, S.5
Carroll, D.6
-
19
-
-
34447319080
-
An improved zincfinger nuclease architecture for highly specific genome editing
-
Miller, J.C., Holmes, M.C., Wang, J., Guschin, D.Y., Lee, Y.L., Rupniewski, I., Beausejour, C.M., Waite, A.J., Wang, N.S., Kim, K.A., Gregory, P.D., Pabo, C.O., and Rebar, E.J. (2007) An improved zincfinger nuclease architecture for highly specific genome editing. Nat Biotechnol. 25, 778-785.
-
(2007)
Nat Biotechnol.
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
Holmes, M.C.2
Wang, J.3
Guschin, D.Y.4
Lee, Y.L.5
Rupniewski, I.6
Beausejour, C.M.7
Waite, A.J.8
Wang, N.S.9
Kim, K.A.10
Gregory, P.D.11
Pabo, C.O.12
Rebar, E.J.13
-
20
-
-
34447323568
-
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
-
Szczepek, M., Brondani, V., Buchel, J., Serrano, L., Segal, D.J., and Cathomen, T. (2007) Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat Biotechnol. 25, 786-793.
-
(2007)
Nat Biotechnol.
, vol.25
, pp. 786-793
-
-
Szczepek, M.1
Brondani, V.2
Buchel, J.3
Serrano, L.4
Segal, D.J.5
Cathomen, T.6
-
21
-
-
25144501447
-
Custom zinc-finger nucleases for use in human cells
-
Alwin, S., Gere, M.B., Guhl, E., Effertz, K., Barbas, C.F., 3rd, Segal, D.J., Weitzman, M.D., and Cathomen, T. (2005) Custom zinc-finger nucleases for use in human cells. Mol Ther. 12, 610-617.
-
(2005)
Mol Ther.
, vol.12
, pp. 610-617
-
-
Alwin, S.1
Gere, M.B.2
Guhl, E.3
Effertz, K.4
Barbas, C.F.5
Segal, D.J.6
Weitzman, M.D.7
Cathomen, T.8
-
22
-
-
38849103093
-
DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases
-
Cornu, T.I., Thibodeau-Beganny, S., Guhl, E., Alwin, S., Eichtinger, M., Joung, J.K., and Cathomen, T. (2008) DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases. Mol Ther. 16, 352-358.
-
(2008)
Mol Ther.
, vol.16
, pp. 352-358
-
-
Cornu, T.I.1
Thibodeau-Beganny, S.2
Guhl, E.3
Alwin, S.4
Eichtinger, M.5
Joung, J.K.6
Cathomen, T.7
-
23
-
-
58149265244
-
Expanding or restricting the target site repertoire of zinc-finger nucleases: The inter-domain linker as a major determinant of target site selectivity
-
Handel, E.M., Alwin, S., and Cathomen, T. (2009) Expanding or restricting the target site repertoire of zinc-finger nucleases: The inter-domain linker as a major determinant of target site selectivity. Mol Ther. 17, 104-111.
-
(2009)
Mol Ther.
, vol.17
, pp. 104-111
-
-
Handel, E.M.1
Alwin, S.2
Cathomen, T.3
-
24
-
-
0030940295
-
Synergy between adjacent zinc fingers in sequence-specific DNA recognition
-
Isalan, M., Choo, Y., and Klug, A. (1997) Synergy between adjacent zinc fingers in sequence-specific DNA recognition. Proc Natl Acad Sci USA. 94, 5617-5621.
-
(1997)
Proc Natl Acad Sci USA.
, vol.94
, pp. 5617-5621
-
-
Isalan, M.1
Choo, Y.2
Klug, A.3
-
25
-
-
33747816812
-
Zinc finger tools: Custom DNA-binding domains for transcription factors and nucleases
-
Mandell, J.G. and Barbas, C.F., 3rd (2006) Zinc finger tools: Custom DNA-binding domains for transcription factors and nucleases. Nucleic Acids Res. 34, W516-W523.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Mandell, J.G.1
Barbas III, C.F.2
|