메뉴 건너뛰기




Volumn 2010, Issue , 2010, Pages

Metabolic and cardiovascular effects of ghrelin

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN 1; GHRELIN; GHRELIN RECEPTOR; GROWTH HORMONE; NITRIC OXIDE;

EID: 79952639015     PISSN: 16879767     EISSN: 16879775     Source Type: Journal    
DOI: 10.1155/2010/864342     Document Type: Review
Times cited : (29)

References (72)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K., Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 1999 402 6762 656 660 (Pubitemid 129516334)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 2
    • 0141761123 scopus 로고    scopus 로고
    • Ghrelin, a widespread hormone: Insights into molecular and cellular regulation of its expression and mechanism of action
    • DOI 10.1016/S0014-5793(03)00965-7
    • Gualillo O., Lago F., Gmez-Reino J., Casanueva F. F., Dieguez C., Ghrelin, a widespread hormone: insights into molecular and cellular regulation of its expression and mechanism of action FEBS Letters 2003 552 2-3 105 109 (Pubitemid 37186843)
    • (2003) FEBS Letters , vol.552 , Issue.2-3 , pp. 105-109
    • Gualillo, O.1    Lago, F.2    Gomez-Reino, J.3    Casanueva, F.F.4    Dieguez, C.5
  • 3
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • DOI 10.1210/er.2002-0029
    • van der Lely A. J., Tschp M., Heiman M. L., Ghigo E., Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin Endocrine Reviews 2004 25 3 426 457 (Pubitemid 38780667)
    • (2004) Endocrine Reviews , vol.25 , Issue.3 , pp. 426-457
    • Van Der Lely, A.J.1    Tschop, M.2    Heiman, M.L.3    Ghigo, E.4
  • 4
    • 12944304591 scopus 로고    scopus 로고
    • Ghrelin: More than a natural GH secretagogue and/or an orexigenic factor
    • DOI 10.1111/j.1365-2265.2004.02160.x
    • Ghigo E., Broglio F., Arvat E., Maccario M., Papotti M., Muccioli G., Ghrelin: more than a natural GH secretagogue and/or an orexigenic factor Clinical Endocrinology 2005 62 1 1 17 (Pubitemid 40175277)
    • (2005) Clinical Endocrinology , vol.62 , Issue.1 , pp. 1-17
    • Ghigo, E.1    Broglio, F.2    Arvat, E.3    Maccario, M.4    Papotti, M.5    Muccioli, G.6
  • 5
    • 29744441392 scopus 로고    scopus 로고
    • Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system
    • DOI 10.1016/j.tem.2005.11.004, PII S1043276005002584
    • Cao J.-M., Ong H., Chen C., Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system Trends in Endocrinology and Metabolism 2006 17 1 13 18 (Pubitemid 43031379)
    • (2006) Trends in Endocrinology and Metabolism , vol.17 , Issue.1 , pp. 13-18
    • Cao, J.-M.1    Ong, H.2    Chen, C.3
  • 6
    • 0035320623 scopus 로고    scopus 로고
    • Ghrelin: Discovery of the natural endogenous ligand for the growth hormone secretagogue receptor
    • PII S1043276000003623
    • Kojima M., Hosoda H., Matsuo H., Kangawa K., Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor Trends in Endocrinology and Metabolism 2001 12 3 118 122 (Pubitemid 33714199)
    • (2001) Trends in Endocrinology and Metabolism , vol.12 , Issue.3 , pp. 118-122
    • Kojima, M.1    Hosoda, H.2    Matsuo, H.3    Kangawa, K.4
  • 9
    • 38849090670 scopus 로고    scopus 로고
    • Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone
    • DOI 10.1016/j.cell.2008.01.017, PII S0092867408001177
    • Yang J., Brown M. S., Liang G., Grishin N. V., Goldstein J. L., Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone Cell 2008 132 3 387 396 (Pubitemid 351192001)
    • (2008) Cell , vol.132 , Issue.3 , pp. 387-396
    • Yang, J.1    Brown, M.S.2    Liang, G.3    Grishin, N.V.4    Goldstein, J.L.5
  • 10
    • 67650423944 scopus 로고    scopus 로고
    • GOAT links dietary lipids with the endocrine control of energy balance
    • Kirchner H., Gutierrez J. A., Solenberg P. J., GOAT links dietary lipids with the endocrine control of energy balance Nature Medicine 2009 15 7 741 745
    • (2009) Nature Medicine , vol.15 , Issue.7 , pp. 741-745
    • Kirchner, H.1    Gutierrez, J.A.2    Solenberg, P.J.3
  • 16
    • 22344435662 scopus 로고    scopus 로고
    • Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats
    • DOI 10.1053/j.gastro.2005.04.015, PII S0016508505006979
    • Chen C.-Y., Inui A., Asakawa A., Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats Gastroenterology 2005 129 1 8 25 (Pubitemid 41002038)
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 8-25
    • Chen, C.-Y.1    Inui, A.2    Asakawa, A.3    Fujino, K.4    Kato, I.5    Chen, C.-C.6    Ueno, N.7    Fujimiya, M.8
  • 17
    • 33645857375 scopus 로고    scopus 로고
    • Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor
    • Toshinai K., Yamaguchi H., Sun Y., Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor Endocrinology 2006 147 5 2306 2314
    • (2006) Endocrinology , vol.147 , Issue.5 , pp. 2306-2314
    • Toshinai, K.1    Yamaguchi, H.2    Sun, Y.3
  • 18
    • 0037521642 scopus 로고    scopus 로고
    • Ghrelin and the regulation of food intake and energy balance
    • Hosoda H., Kojima M., Kangawa K., Ghrelin and the regulation of food intake and energy balance Molecular Interventions 2002 2 8 494 503
    • (2002) Molecular Interventions , vol.2 , Issue.8 , pp. 494-503
    • Hosoda, H.1    Kojima, M.2    Kangawa, K.3
  • 19
    • 0141643291 scopus 로고    scopus 로고
    • Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes
    • DOI 10.2337/diabetes.52.10.2546
    • Pykk S. M., Kellokoski E., Hrkk S., Kauma H., Kesniemi Y. A., Ukkola O., Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes Diabetes 2003 52 10 2546 2553 (Pubitemid 37210544)
    • (2003) Diabetes , vol.52 , Issue.10 , pp. 2546-2553
    • Poykko, S.M.1    Kellokoski, E.2    Horkko, S.3    Kauma, H.4    Kesaniemi, Y.A.5    Ukkola, O.6
  • 21
    • 0346494433 scopus 로고    scopus 로고
    • Ghrelin levels in obesity and anorexia nervosa: Effect of weight reduction or recuperation
    • DOI 10.1016/j.jpeds.2003.10.036
    • Soriano-Guillén L., Barrios V., Campos-Barros., Argente J., Ghrelin levels in obesity and anorexia nervosa: effect of weight reduction or recuperation Journal of Pediatrics 2004 144 1 36 42 (Pubitemid 38091419)
    • (2004) Journal of Pediatrics , vol.144 , Issue.1 , pp. 36-42
    • Soriano-Guillen, L.1    Barrios, V.2    Campos-Barros, A.3    Argente, J.4
  • 24
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M., Smiley D. L., Heiman M. L., Ghrelin induces adiposity in rodents Nature 2000 407 6806 908 913
    • (2000) Nature , vol.407 , Issue.6806 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 25
    • 0344467063 scopus 로고    scopus 로고
    • Endocrine responses to the oral ingestion of a physiological dose of essential amino acids in humans
    • DOI 10.1677/joe.0.1790237
    • Groschl M., Knerr I., Topf H.-G., Schmid P., Rascher W., Rauh M., Endocrine responses to the oral ingestion of a physiological dose of essential amino acids in humans Journal of Endocrinology 2003 179 2 237 244 (Pubitemid 37461353)
    • (2003) Journal of Endocrinology , vol.179 , Issue.2 , pp. 237-244
    • Groschl, M.1    Knerr, I.2    Topf, H.-G.3    Schmid, P.4    Rascher, W.5    Rauh, M.6
  • 26
    • 0242266549 scopus 로고    scopus 로고
    • Differential effect of protein and fat on plasma ghrelin levels in man
    • DOI 10.1016/S0167-0115(03)00195-2
    • Erdmann J., Lippl F., Schusdziarra V., Differential effect of protein and fat on plasma ghrelin levels in man Regulatory Peptides 2003 116 13 101 107 (Pubitemid 37352921)
    • (2003) Regulatory Peptides , vol.116 , Issue.1-3 , pp. 101-107
    • Erdmann, J.1    Lippl, F.2    Schusdziarra, V.3
  • 28
    • 33947098380 scopus 로고    scopus 로고
    • Role of endogenous ghrelin in growth hormone secretion, appetite regulation and metabolism
    • DOI 10.1007/s11154-006-9022-0, Special issue on Growth and Development, Guest editor: John Fowlkes
    • Dimaraki E. V., Jaffe C. A., Role of endogenous ghrelin in growth hormone secretion, appetite regulation and metabolism Reviews in Endocrine and Metabolic Disorders 2006 7 4 237 249 (Pubitemid 46399313)
    • (2006) Reviews in Endocrine and Metabolic Disorders , vol.7 , Issue.4 , pp. 237-249
    • Dimaraki, E.V.1    Jaffe, C.A.2
  • 32
    • 0036925201 scopus 로고    scopus 로고
    • Plasma ghrelin, obesity, and the polycystic ovary syndrome: Correlation with insulin resistance and androgen levels
    • DOI 10.1210/jc.2002-020776
    • Pagotto U., Gambineri A., Vicennati V., Heiman M. L., Tschp M., Pasquali R., Plasma ghrelin, obesity, and the polycystic ovary syndrome: correlation with insulin resistance and androgen levels Journal of Clinical Endocrinology and Metabolism 2002 87 12 5625 5629 (Pubitemid 36034369)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.12 , pp. 5625-5629
    • Pagotto, U.1    Gambineri, A.2    Vicennati, V.3    Heiman, M.L.4    Tschop, M.5    Pasquali, R.6
  • 33
    • 0345375270 scopus 로고    scopus 로고
    • Plasma ghrelin, body fat, insulin resistance, and smoking in clinically healthy men: The atherosclerosis and insulin resistance study
    • DOI 10.1016/S0026-0495(03)00274-9
    • Fagerberg B., Hultén L. M., Hulthe J., Plasma ghrelin, body fat, insulin resistance, and smoking in clinically healthy men: the atherosclerosis and insulin resistance study Metabolism 2003 52 11 1460 1463 (Pubitemid 37461115)
    • (2003) Metabolism: Clinical and Experimental , vol.52 , Issue.11 , pp. 1460-1463
    • Fagerberg, B.1    Hulten, L.M.2    Hulthe, J.3
  • 35
    • 20444504386 scopus 로고    scopus 로고
    • Relationships between fasting plasma ghrelin levels and metabolic parameters in children and adolescents
    • DOI 10.1016/j.metabol.2005.02.007, PII S0026049505000946
    • Hye S. P., Lee K.-U., Young S. K., Cheol Y. P., Relationships between fasting plasma ghrelin levels and metabolic parameters in children and adolescents Metabolism 2005 54 7 925 929 (Pubitemid 40827209)
    • (2005) Metabolism: Clinical and Experimental , vol.54 , Issue.7 , pp. 925-929
    • Hye, S.P.1    Lee, K.-U.2    Young, S.K.3    Cheol, Y.P.4
  • 36
    • 0344394289 scopus 로고    scopus 로고
    • Vagotomy Dissociates Short- and Long-Term Controls of Circulating Ghrelin
    • DOI 10.1210/en.2003-1059
    • Williams D. L., Grill H. J., Cummings D. E., Kaplan J. M., Vagotomy dissociates short- and long-term controls of circulating ghrelin Endocrinology 2003 144 12 5184 5187 (Pubitemid 37476045)
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5184-5187
    • Williams, D.L.1    Grill, H.J.2    Cummings, D.E.3    Kaplan, J.M.4
  • 39
    • 22044441761 scopus 로고    scopus 로고
    • Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice
    • DOI 10.1016/j.regpep.2005.04.004, PII S0167011505001205
    • Tsubone T., Masaki T., Katsuragi I., Tanaka K., Kakuma T., Yoshimatsu H., Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice Regulatory Peptides 2005 130 1-2 97 103 (Pubitemid 40966028)
    • (2005) Regulatory Peptides , vol.130 , Issue.1-2 , pp. 97-103
    • Tsubone, T.1    Masaki, T.2    Katsuragi, I.3    Tanaka, K.4    Kakuma, T.5    Yoshimatsu, H.6
  • 48
    • 29144466031 scopus 로고    scopus 로고
    • Functional and immunocytochemical evidence for a role of ghrelin and des-octanoyl ghrelin in the regulation of vascular tone in man
    • DOI 10.1016/j.cardiores.2005.09.001, PII S0008636305004360
    • Kleinz M. J., Maguire J. J., Skepper J. N., Davenport A. P., Functional and immunocytochemical evidence for a role of ghrelin and des-octanoyl ghrelin in the regulation of vascular tone in man Cardiovascular Research 2006 69 1 227 235 (Pubitemid 41814824)
    • (2006) Cardiovascular Research , vol.69 , Issue.1 , pp. 227-235
    • Kleinz, M.J.1    Maguire, J.J.2    Skepper, J.N.3    Davenport, A.P.4
  • 49
    • 0034741715 scopus 로고    scopus 로고
    • 9]-Ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue; up-regulation of receptors with atherosclerosis
    • Katugampola S. D., Pallikaros Z., Davenport A. P., [125I-His9]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue; up-regulation of receptors with atherosclerosis British Journal of Pharmacology 2001 134 1 143 149 (Pubitemid 32835477)
    • (2001) British Journal of Pharmacology , vol.134 , Issue.1 , pp. 143-149
    • Katugampola, S.D.1    Pallikaros, Z.2    Davenport, A.P.3
  • 52
    • 0242383502 scopus 로고    scopus 로고
    • Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart
    • DOI 10.1007/s00395-003-0434-7
    • Frascarelli S., Ghelardoni S., Ronca-Testoni S., Zucchi R., Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart Basic Research in Cardiology 2003 98 6 401 405 (Pubitemid 37336627)
    • (2003) Basic Research in Cardiology , vol.98 , Issue.6 , pp. 401-405
    • Frascarelli, S.1    Ghelardoni, S.2    Ronca-Testoni, S.3    Zucchi, R.4
  • 54
    • 0035026511 scopus 로고    scopus 로고
    • Hemodynamic and hormonal effects of human ghrelin in healthy volunteers
    • Nagaya N., Kojima M., Uematsu M., Hemodynamic and hormonal effects of human ghrelin in healthy volunteers American Journal of Physiology 2001 280 5 R1483 R1487
    • (2001) American Journal of Physiology , vol.280 , Issue.5
    • Nagaya, N.1    Kojima, M.2    Uematsu, M.3
  • 55
    • 20844460120 scopus 로고    scopus 로고
    • Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
    • DOI 10.1161/01.CIR.0000149746.62908.BB
    • Nagaya N., Moriya J., Yasumura Y., Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure Circulation 2004 110 24 3674 3679 (Pubitemid 39665256)
    • (2004) Circulation , vol.110 , Issue.24 , pp. 3674-3679
    • Nagaya, N.1    Moriya, J.2    Yasumura, Y.3    Uematsu, M.4    Ono, F.5    Shimizu, W.6    Ueno, K.7    Kitakaze, M.8    Miyatake, K.9    Kangawa, K.10
  • 56
    • 33644809274 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing peptide, in the treatment of cardiopulmonary-associated cachexia
    • DOI 10.2169/internalmedicine.45.1402
    • Nagaya N., Kojima M., Kangawa K., Ghrelin, a novel growth hormone-releasing peptide, in the treatment of cardiopulmonary-associated cachexia Internal Medicine 2006 45 3 127 134 (Pubitemid 43349437)
    • (2006) Internal Medicine , vol.45 , Issue.3 , pp. 127-134
    • Nagaya, N.1    Kojima, M.2    Kangawa, K.3
  • 58
    • 52249099899 scopus 로고    scopus 로고
    • Ghrelin as a potential blood pressure reducing factor in obese women during weight loss treatment
    • Mizia-Stec K., Zahorska-Markiewicz B., Olszanecka-Glinianowicz M., Ghrelin as a potential blood pressure reducing factor in obese women during weight loss treatment Endokrynologia Polska 2008 59 3 207 211
    • (2008) Endokrynologia Polska , vol.59 , Issue.3 , pp. 207-211
    • Mizia-Stec, K.1    Zahorska-Markiewicz, B.2    Olszanecka-Glinianowicz, M.3
  • 59
    • 38149032717 scopus 로고    scopus 로고
    • Ghrelin suppresses cardiac sympathetic activity and prevents early left ventricular remodeling in rats with myocardial infarction
    • Soeki T., Kishimoto I., Schwenke D. O., Ghrelin suppresses cardiac sympathetic activity and prevents early left ventricular remodeling in rats with myocardial infarction American Journal of Physiology 2008 294 1 H426 H432
    • (2008) American Journal of Physiology , vol.294 , Issue.1
    • Soeki, T.1    Kishimoto, I.2    Schwenke, D.O.3
  • 60
    • 33644835427 scopus 로고    scopus 로고
    • Ghrelin and cardiovascular health
    • DOI 10.1016/j.coph.2005.10.006, PII S1471489206000191
    • Garca E. A., Korbonits M., Ghrelin and cardiovascular health Current Opinion in Pharmacology 2006 6 2 142 147 (Pubitemid 43362127)
    • (2006) Current Opinion in Pharmacology , vol.6 , Issue.2 , pp. 142-147
    • Garcia, E.A.1    Korbonits, M.2
  • 61
    • 0036687932 scopus 로고    scopus 로고
    • Comparison of vasodilators in human internal mammary artery: Ghrelin is a potent physiological antagonist of endothelin-1
    • DOI 10.1038/sj.bjp.0704815
    • Wiley K. E., Davenport A. P., Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1 British Journal of Pharmacology 2002 136 8 1146 1152 (Pubitemid 34970066)
    • (2002) British Journal of Pharmacology , vol.136 , Issue.8 , pp. 1146-1152
    • Wiley, K.E.1    Davenport, A.P.2
  • 63
    • 33947188045 scopus 로고    scopus 로고
    • Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells
    • Iantorno M., Chen H., Kim J.-A., Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells American Journal of Physiology 2007 292 3 E756 E764
    • (2007) American Journal of Physiology , vol.292 , Issue.3
    • Iantorno, M.1    Chen, H.2    Kim, J.-A.3
  • 64
    • 70449717382 scopus 로고    scopus 로고
    • Ghrelin restores the endothelin 1/nitric oxide balance in patients with obesity-related metabolic syndrome
    • Tesauro M., Schinzari F., Rovella V., Ghrelin restores the endothelin 1/nitric oxide balance in patients with obesity-related metabolic syndrome Hypertension 2009 54 5 995 1000
    • (2009) Hypertension , vol.54 , Issue.5 , pp. 995-1000
    • Tesauro, M.1    Schinzari, F.2    Rovella, V.3
  • 70
    • 13844270518 scopus 로고    scopus 로고
    • Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats
    • Granado M., Priego T., Martn A. I., Villana M., Lpez-Caldern A., Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats American Journal of Physiology 2005 288 3 E486 E492
    • (2005) American Journal of Physiology , vol.288 , Issue.3
    • Granado, M.1    Priego, T.2    Martn, A.I.3    Villana, M.4    Lpez-Caldern, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.