-
1
-
-
0037116641
-
Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
-
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey. JAMA. 2002;287:356-359.
-
(2002)
JAMA
, vol.287
, pp. 356-359
-
-
Ford, E.S.1
Giles, W.H.2
Dietz, W.H.3
-
2
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn BB, Flier JS. Obesity and insulin resistance. J Clin invest. 2000;106:473-481.
-
(2000)
J Clin Invest
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
3
-
-
0347985272
-
Obesity-induced inflammatory changes in adipose tissues
-
Wellen KE, Hotamisligil GS. Obesity-induced inflammatory changes in adipose tissues. J Clin Invest. 2003;112:1785-1788.
-
(2003)
J Clin Invest
, vol.112
, pp. 1785-1788
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
4
-
-
15444366991
-
Metabolic syndrome: A comprehensive perspective based on interactions between obesity, diabetes, and inflammation
-
Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R. Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation. 2005;111:1448-1454.
-
(2005)
Circulation
, vol.111
, pp. 1448-1454
-
-
Dandona, P.1
Aljada, A.2
Chaudhuri, A.3
Mohanty, P.4
Garg, R.5
-
5
-
-
0037396469
-
The metabolic syndrome is associated with elevated circulating C reactive protein in healthy reference range, a systemic low grade inflammatory state
-
Tamakoshi K, Yatsuya H, Kondo T, Hori Y, Ishikawa M, Zhang H, Murata C, Otsuka R, Zhu S, Toyoshima H. The metabolic syndrome is associated with elevated circulating C reactive protein in healthy reference range, a systemic low grade inflammatory state. Int J Obes Relat Metabol Disord. 2003;27:443-449.
-
(2003)
Int J Obes Relat Metabol Disord
, vol.27
, pp. 443-449
-
-
Tamakoshi, K.1
Yatsuya, H.2
Kondo, T.3
Hori, Y.4
Ishikawa, M.5
Zhang, H.6
Murata, C.7
Otsuka, R.8
Zhu, S.9
Toyoshima, H.10
-
6
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature. 2002;420:868-874.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
7
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999;402:656-660.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
8
-
-
0040184557
-
Ghrelin strongly stimulates growth hormone release in humans
-
Takaya K, Ariyasu H, Kanamoto N, Iwakura H, Yoshimoto A, Harada M, Mori K, Komatsu Y, Usui T, Shimatsu A, Ogawa Y, Hosoda K, Akamizu T, Koijma M, Kangawa K, Nakao K. Ghrelin strongly stimulates growth hormone release in humans. J Clin Endocrinol Metab. 2000;85:4908-4911.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4908-4911
-
-
Takaya, K.1
Ariyasu, H.2
Kanamoto, N.3
Iwakura, H.4
Yoshimoto, A.5
Harada, M.6
Mori, K.7
Komatsu, Y.8
Usui, T.9
Shimatsu, A.10
Ogawa, Y.11
Hosoda, K.12
Akamizu, T.13
Koijma, M.14
Kangawa, K.15
Nakao, K.16
-
9
-
-
0034741715
-
125I-His(9)]-Ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: Up-regulation of receptors with atherosclerosis
-
125I-His(9)]- Ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with atherosclerosis. Br J Pharmacol. 2001;134:143-149.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 143-149
-
-
Katugampola, S.D.1
Pallikaros, Z.2
Davenport, A.P.3
-
10
-
-
0035026511
-
Hemodynamic and hormonal effects of human ghrelin in healthy volunteers
-
Nagaya N, Koijma M, Uematsu M, Yamagishi M, Hosoda H, Oya H, Hayashi Y, Kangawa K. Hemodynamic and hormonal effects of human ghrelin in healthy volunteers. Am J Physiol. 2001;280:RI483-RI487.
-
(2001)
Am J Physiol
, vol.280
-
-
Nagaya, N.1
Koijma, M.2
Uematsu, M.3
Yamagishi, M.4
Hosoda, H.5
Oya, H.6
Hayashi, Y.7
Kangawa, K.8
-
11
-
-
20844460120
-
Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
-
Nagaya N, Moriya J, Yasumura Y, Uematsu M, Ono F, Shimizu W, Ueno K, Kitakaze M, Miyatake K, Kangawa K. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation. 2004;110:3674-3679.
-
(2004)
Circulation
, vol.110
, pp. 3674-3679
-
-
Nagaya, N.1
Moriya, J.2
Yasumura, Y.3
Uematsu, M.4
Ono, F.5
Shimizu, W.6
Ueno, K.7
Kitakaze, M.8
Miyatake, K.9
Kangawa, K.10
-
12
-
-
3242749843
-
Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells
-
Dixit VD, Schaffer EM, Pyle RS, Collins GD, Sakthivel SK, Palaniappan R, Lillard JW, Taub DD. Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J Clin Invest. 2004;114:57-66.
-
(2004)
J Clin Invest
, vol.114
, pp. 57-66
-
-
Dixit, V.D.1
Schaffer, E.M.2
Pyle, R.S.3
Collins, G.D.4
Sakthivel, S.K.5
Palaniappan, R.6
Lillard, J.W.7
Taub, D.D.8
-
13
-
-
2442419837
-
Ghrelin inhibits proinflammatory responses and nuclear factor-κB activation in human endothelial cells
-
Li WG, Gavrila D, Liu X, Wang L, Gunnlaugsson S, Stoll LL, McCormick ML, Sigmund CD, Tang C, Weintraub NL. Ghrelin inhibits proinflammatory responses and nuclear factor-κB activation in human endothelial cells. Circulation. 2004;109:2221-2226.
-
(2004)
Circulation
, vol.109
, pp. 2221-2226
-
-
Li, W.G.1
Gavrila, D.2
Liu, X.3
Wang, L.4
Gunnlaugsson, S.5
Stoll, L.L.6
McCormick, M.L.7
Sigmund, C.D.8
Tang, C.9
Weintraub, N.L.10
-
14
-
-
18244391222
-
Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion
-
Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, Nozoe S-I, Hosoda H, Kangawa K, Matzukura S. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab. 2002;87:240-244.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 240-244
-
-
Shiiya, T.1
Nakazato, M.2
Mizuta, M.3
Date, Y.4
Mondal, M.S.5
Tanaka, M.6
Nozoe, S.-I.7
Hosoda, H.8
Kangawa, K.9
Matzukura, S.10
-
15
-
-
0141643291
-
Low plasma ghrelin is associated with insulin resistance, hypertension and the prevalence of type 2 diabetes
-
Pöykkö SM, Kellokoski E, Hörkkö S, Kauma H, Kesäniemi YA, Ukkola O. Low plasma ghrelin is associated with insulin resistance, hypertension and the prevalence of type 2 diabetes. Diabetes. 2003;52:2546-2553.
-
(2003)
Diabetes
, vol.52
, pp. 2546-2553
-
-
Pöykkö, S.M.1
Kellokoski, E.2
Hörkkö, S.3
Kauma, H.4
Kesäniemi, Y.A.5
Ukkola, O.6
-
16
-
-
0842277242
-
Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
-
Grundy SM, Brewer HB, Gleeman JI, Smith SC, Lenfant C. Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation. 2004;109:433-438.
-
(2004)
Circulation
, vol.109
, pp. 433-438
-
-
Grundy, S.M.1
Brewer, H.B.2
Gleeman, J.I.3
Smith, S.C.4
Lenfant, C.5
-
17
-
-
0034456568
-
Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans
-
Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85:2402-2410.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2402-2410
-
-
Katz, A.1
Nambi, S.S.2
Mather, K.3
Baron, A.D.4
Follmann, D.A.5
Sullivan, G.6
Quon, M.J.7
-
18
-
-
0035082265
-
Circulating ghrelin levels are decreased in human obesity
-
Tschöp M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes. 2001;50:707-709.
-
(2001)
Diabetes
, vol.50
, pp. 707-709
-
-
Tschöp, M.1
Weyer, C.2
Tataranni, P.A.3
Devanarayan, V.4
Ravussin, E.5
Heiman, M.L.6
-
19
-
-
1942473108
-
Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls
-
McLaughlin T, Abbasi F, Lamendola C, Frayo RS, Cummings DE. Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls. J Clin Endocrinol Metab. 2004;89:1630-1635.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1630-1635
-
-
McLaughlin, T.1
Abbasi, F.2
Lamendola, C.3
Frayo, R.S.4
Cummings, D.E.5
-
20
-
-
0036925201
-
Plasma ghrelin, obesity, and the polycystic ovary syndrome: Correlation with insulin resistance and androgen levels
-
Pagotto U, Gambineri A, Vicennati V, Heiman ML, Tschöp M, Pasquali R. Plasma ghrelin, obesity, and the polycystic ovary syndrome: correlation with insulin resistance and androgen levels. J Clin Endocrinol Metab. 2002;87:5625-5629.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 5625-5629
-
-
Pagotto, U.1
Gambineri, A.2
Vicennati, V.3
Heiman, M.L.4
Tschöp, M.5
Pasquali, R.6
-
21
-
-
0036687932
-
Comparison of vasodilators in human internal mammary artery: Ghrelin is a potent physiological antagonist of endothelin-1
-
Wiley KE, Davenport AP. Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1. Br J Pharmacol. 2002;136:1146-1152.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 1146-1152
-
-
Wiley, K.E.1
Davenport, A.P.2
-
22
-
-
0141868869
-
Ghrelin improves endothelial dysfunction through growth hormone-independent mechanisms in rats
-
Shimizu Y, Nagaya N, Teranishi Y, Imazu M, Yamamoto H, Shokawa T, Kangawa K, Kohno N, Yoshizumi M. Ghrelin improves endothelial dysfunction through growth hormone-independent mechanisms in rats. Biochem Biophys Res Commun. 2003;310:830-835.
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 830-835
-
-
Shimizu, Y.1
Nagaya, N.2
Teranishi, Y.3
Imazu, M.4
Yamamoto, H.5
Shokawa, T.6
Kangawa, K.7
Kohno, N.8
Yoshizumi, M.9
-
23
-
-
13844298724
-
Endothelial inflammation in insulin resistance
-
Sjoholm A, Nystrom T. Endothelial inflammation in insulin resistance. Lancet. 2005;365:610-612.
-
(2005)
Lancet
, vol.365
, pp. 610-612
-
-
Sjoholm, A.1
Nystrom, T.2
-
24
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
-
Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation. 2000;101:1539-1545.
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
Cong, L.N.4
Kirby, M.5
Mostowski, H.6
Quon, M.J.7
-
25
-
-
0141671792
-
Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium
-
Vincent MA, Montagnard M, Quon MJ. Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium. Curr Diab Rep. 2003;3:279-288.
-
(2003)
Curr Diab Rep
, vol.3
, pp. 279-288
-
-
Vincent, M.A.1
Montagnard, M.2
Quon, M.J.3
-
26
-
-
0038665339
-
The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance
-
Vicent D, Ilany J, Kondo T, Naruse K, Fisher SJ, Kisanuki YY, Bursell S, Yanagisawa M, King GL, Kahn CR. The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest. 2003;111:1373-1380.
-
(2003)
J Clin Invest
, vol.111
, pp. 1373-1380
-
-
Vicent, D.1
Ilany, J.2
Kondo, T.3
Naruse, K.4
Fisher, S.J.5
Kisanuki, Y.Y.6
Bursell, S.7
Yanagisawa, M.8
King, G.L.9
Kahn, C.R.10
-
27
-
-
6344291317
-
Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity
-
Gauna C, Meyler FM, Janssen JA, Delhanty PJ, Abribat T, van Koetsveld P, Hofland LJ, Broglio F, Ghigo E, van der Lely AJ. Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity. J Clin Endocrinol Metab. 2004;89:5035-5042.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5035-5042
-
-
Gauna, C.1
Meyler, F.M.2
Janssen, J.A.3
Delhanty, P.J.4
Abribat, T.5
Van Koetsveld, P.6
Hofland, L.J.7
Broglio, F.8
Ghigo, E.9
Van Der Lely, A.J.10
-
28
-
-
0037164747
-
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERKI/2 and PI 3-kinase/AKT
-
Baldanzi G, Filigheddu N, Cutrupi S, Catapano F, Bonissoni S, Fubini A, Malan D, Baj G, Granata R, Broglio F, Papotti M, Surico N, Bussolino F, Isgaard J, Deghenghi R, Sinigaglia F, Prat M, Muccioli G, Ghigo E, Graziani A. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERKI/2 and PI 3-kinase/AKT. J Cell Biol. 2002;159:1029-1037.
-
(2002)
J Cell Biol
, vol.159
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
Catapano, F.4
Bonissoni, S.5
Fubini, A.6
Malan, D.7
Baj, G.8
Granata, R.9
Broglio, F.10
Papotti, M.11
Surico, N.12
Bussolino, F.13
Isgaard, J.14
Deghenghi, R.15
Sinigaglia, F.16
Prat, M.17
Muccioli, G.18
Ghigo, E.19
Graziani, A.20
more..
-
29
-
-
7244251619
-
Ghrelin and synthetic growth hormone secretagogues are cardioactive molecules with identities and differences
-
Benso A, Broglio F, Marafetti L, Lucatello B, Seardo MA, Granata R, Martina V, Papotti M, Muccioli G, Ghigo E. Ghrelin and synthetic growth hormone secretagogues are cardioactive molecules with identities and differences. Semin Vasc Med. 2004;4:107-114.
-
(2004)
Semin Vasc Med
, vol.4
, pp. 107-114
-
-
Benso, A.1
Broglio, F.2
Marafetti, L.3
Lucatello, B.4
Seardo, M.A.5
Granata, R.6
Martina, V.7
Papotti, M.8
Muccioli, G.9
Ghigo, E.10
-
30
-
-
0037162116
-
Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery
-
Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JQ. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 2002;346:1623-1630.
-
(2002)
N Engl J Med
, vol.346
, pp. 1623-1630
-
-
Cummings, D.E.1
Weigle, D.S.2
Frayo, R.S.3
Breen, P.A.4
Ma, M.K.5
Dellinger, E.P.6
Purnell, J.Q.7
-
31
-
-
14044263649
-
Human plasma ghrelin levels increase during a one-year exercise program
-
Foster-Schubert KE, McTiernan A, Frayo RS, Schwartz RS, Rajan KB, Yasui Y, Tworoger SS, Cummings DE. Human plasma ghrelin levels increase during a one-year exercise program. J Clin Endocrinol Metab. 2005;90:820-825.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 820-825
-
-
Foster-Schubert, K.E.1
McTiernan, A.2
Frayo, R.S.3
Schwartz, R.S.4
Rajan, K.B.5
Yasui, Y.6
Tworoger, S.S.7
Cummings, D.E.8
|