Structure-function study of a Plasmodium falciparum Hsp70 using three dimensional modelling and in Vitro analyses

Protein and Peptide Letters

Volumn 15, Issue 10, 2008, Pages 1117-1125

  Shonhai, Addmore ^a,b   Botha, Melissa ^a   De Beer, Tjaart A P ^c   Boshoff, Aileen ^a   Blatch, Gregory L ^a  

^a RHODES UNIVERSITY   (South Africa)

^b UNIVERSITY OF ZULULAND   (South Africa)

^c UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Hsp40; Malaria; Molecular chaperone; PfHsp70; Substrate binding cavity; Suppression of MDH aggregation

Indexed keywords

ADENOSINE TRIPHOSPHATE; HEAT SHOCK PROTEIN 70; MALATE DEHYDROGENASE; PROTOZOAL PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; HUMAN; HYDROPHOBICITY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; TEMPERATURE;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYDROPHOBICITY; MALATE DEHYDROGENASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

PLASMODIUM FALCIPARUM;

EID: 54249123736     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986608786071067     Document Type: Article

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