메뉴 건너뛰기




Volumn 93, Issue 4, 2011, Pages 749-757

HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death

Author keywords

Apoptosis resistance; Cyclooxygenase 2; HT 29 colorectal cancer cells; Ursolic acid

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; URSOLIC ACID;

EID: 79952447295     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.01.003     Document Type: Article
Times cited : (47)

References (56)
  • 5
  • 6
    • 0036521678 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs, apoptosis, and colon-cancer chemoprevention
    • T.A. Chan Nonsteroidal anti-inflammatory drugs, apoptosis, and colon-cancer chemoprevention Lancet Oncol. 3 2002 166 174
    • (2002) Lancet Oncol. , vol.3 , pp. 166-174
    • Chan, T.A.1
  • 7
    • 30044432923 scopus 로고    scopus 로고
    • Fishing for prostanoids: Deciphering the developmental functions of cyclooxygenase-derived prostaglandins
    • DOI 10.1016/j.ydbio.2005.10.013, PII S0012160605007219
    • Y.I. Cha, L. Solnica-Krezel, and R.N. DuBois Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins Dev. Biol. 289 2006 263 272 (Pubitemid 43049931)
    • (2006) Developmental Biology , vol.289 , Issue.2 , pp. 263-272
    • Cha, Y.I.1    Solnica-Krezel, L.2    DuBois, R.N.3
  • 8
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • W.L. Smith, D.L. DeWitt, and R.M. Garavito Cyclooxygenases: structural, cellular, and molecular biology Annu. Rev. Biochem. 69 2000 145 182
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 145-182
    • Smith, W.L.1    Dewitt, D.L.2    Garavito, R.M.3
  • 10
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • D.A. Jones, D.P. Carlton, T.M. McIntyre, G.A. Zimmerman, and S.M. Prescott Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines J. Biol. Chem. 268 1993 9049 9054 (Pubitemid 23118701)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.12 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 11
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • D.A. Kujubu, B.S. Fletcher, B.C. Varnum, R.W. Lim, and H.R. Herschman TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue J. Biol. Chem. 266 1991 12866 12872
    • (1991) J. Biol. Chem. , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 12
    • 0030770386 scopus 로고    scopus 로고
    • Aspirin use and potential mechanisms for colorectal cancer prevention
    • C.S. Williams, W. Smalley, and R.N. DuBois Aspirin use and potential mechanisms for colorectal cancer prevention J. Clin. Invest. 100 1997 1325 1329 (Pubitemid 27425755)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.6 , pp. 1325-1329
    • Williams, C.S.1    Smalley, W.2    DuBois, R.N.3
  • 14
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • C.E. Eberhart, R.J. Coffey, A. Radhika, F.M. Giardiello, S. Ferrenbach, and R.N. DuBois Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas Gastroenterology 107 1994 1183 1188 (Pubitemid 24294584)
    • (1994) Gastroenterology , vol.107 , Issue.4 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    DuBois, R.N.6
  • 16
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in Apc(δ716) knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • DOI 10.1016/S0092-8674(00)81988-1
    • M. Oshima, J.E. Dinchuk, S.L. Kargman, H. Oshima, B. Hancock, E. Kwong, J.M. Trzaskos, J.F. Evans, and M.M. Taketo Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) Cell 87 1996 803 809 (Pubitemid 26404280)
    • (1996) Cell , vol.87 , Issue.5 , pp. 803-809
    • Oshima, M.1    Dinchuk, J.E.2    Kargman, S.L.3    Oshima, H.4    Hancock, B.5    Kwong, E.6    Trzaskos, J.M.7    Evans, J.F.8    Taketo, M.M.9
  • 18
    • 1642494834 scopus 로고    scopus 로고
    • 2, a Survival Factor for Tumor and Associated Vasculature
    • DOI 10.1158/0008-5472.CAN-03-1168
    • T.W. Davis, J.M. O'Neal, M.D. Pagel, B.S. Zweifel, P.P. Mehta, D.M. Heuvelman, and J.L. Masferrer Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature Cancer Res. 64 2004 279 285 (Pubitemid 38114108)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 279-285
    • Davis, T.W.1    O'Neal, J.M.2    Pagel, M.D.3    Zweifel, B.S.4    Mehta, P.P.5    Heuvelman, D.M.6    Masferrer, J.L.7
  • 19
    • 0036829336 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells
    • Y. Sun, X.M. Tang, E. Half, M.T. Kuo, and F.A. Sinicrope Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells Cancer Res. 62 2002 6323 6328 (Pubitemid 35244488)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6323-6328
    • Sun, Y.1    Tang, X.M.2    Half, E.3    Kuo, M.T.4    Sinicrope, F.A.5
  • 20
    • 33746136946 scopus 로고    scopus 로고
    • Overexpression of Cox-2 in human osteosarcoma cells decreases proliferation and increases apoptosis
    • DOI 10.1158/0008-5472.CAN-05-3624
    • Z. Xu, S. Choudhary, O. Voznesensky, M. Mehrotra, M. Woodard, M. Hansen, H. Herschman, and C. Pilbeam Overexpression of COX-2 in human osteosarcoma cells decreases proliferation and increases apoptosis Cancer Res. 66 2006 6657 6664 (Pubitemid 44085622)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6657-6664
    • Xu, Z.1    Choudhary, S.2    Voznesensky, O.3    Mehrotra, M.4    Woodard, M.5    Hansen, M.6    Herschman, H.7    Pilbeam, C.8
  • 22
    • 0034193436 scopus 로고    scopus 로고
    • Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells
    • K. Subbaramaiah, P. Michaluart, M.B. Sporn, and A.J. Dannenberg Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells Cancer Res. 60 2000 2399 2404 (Pubitemid 30262429)
    • (2000) Cancer Research , vol.60 , Issue.9 , pp. 2399-2404
    • Subbaramaiah, K.1    Michaluart, P.2    Sporn, M.B.3    Dannenberg, A.J.4
  • 23
    • 0042530176 scopus 로고    scopus 로고
    • Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase
    • D. Andersson, J.J. Liu, A. Nilsson, and R.D. Duan Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase Anticancer Res. 23 2003 3317 3322 (Pubitemid 36975429)
    • (2003) Anticancer Research , vol.23 , Issue.4 , pp. 3317-3322
    • Andersson, D.1    Liu, J.-J.2    Nilsson, A.3    Duan, R.-D.4
  • 24
    • 77953696173 scopus 로고    scopus 로고
    • Enhancement of chemotherapeutic agent-induced apoptosis by inhibition of NF-kappaB using ursolic acid
    • Y. Li, D. Xing, Q. Chen, and W.R. Chen Enhancement of chemotherapeutic agent-induced apoptosis by inhibition of NF-kappaB using ursolic acid Int. J. Cancer 127 2010 462 473
    • (2010) Int. J. Cancer , vol.127 , pp. 462-473
    • Li, Y.1    Xing, D.2    Chen, Q.3    Chen, W.R.4
  • 25
    • 77749311412 scopus 로고    scopus 로고
    • Ursolic acid overcomes Bcl-2-mediated resistance to apoptosis in prostate cancer cells involving activation of JNK-induced Bcl-2 phosphorylation and degradation
    • Y.X. Zhang, C.Z. Kong, L.H. Wang, J.Y. Li, X.K. Liu, B. Xu, C.L. Xu, and Y.H. Sun Ursolic acid overcomes Bcl-2-mediated resistance to apoptosis in prostate cancer cells involving activation of JNK-induced Bcl-2 phosphorylation and degradation J. Cell Biochem. 109 2010 764 773
    • (2010) J. Cell Biochem. , vol.109 , pp. 764-773
    • Zhang, Y.X.1    Kong, C.Z.2    Wang, L.H.3    Li, J.Y.4    Liu, X.K.5    Xu, B.6    Xu, C.L.7    Sun, Y.H.8
  • 26
    • 35848953411 scopus 로고    scopus 로고
    • Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin hydrolyzing enzymes in azoxymethane-treated rats
    • DOI 10.1007/s00432-007-0255-4
    • D. Andersson, Y. Cheng, and R.D. Duan Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin hydrolyzing enzymes in azoxymethane-treated rats J. Cancer Res. Clin. Oncol. 134 2008 101 107 (Pubitemid 350060690)
    • (2008) Journal of Cancer Research and Clinical Oncology , vol.134 , Issue.1 , pp. 101-107
    • Andersson, D.1    Cheng, Y.2    Duan, R.-D.3
  • 27
    • 77956941684 scopus 로고    scopus 로고
    • Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor
    • L. Yang, X. Liu, Z. Lu, C.J. Yuet-Wa, L. Zhou, K.P. Fung, P. Wu, and S. Wu Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor Cancer Lett. 298 2010 128 138
    • (2010) Cancer Lett. , vol.298 , pp. 128-138
    • Yang, L.1    Liu, X.2    Lu, Z.3    Yuet-Wa, C.J.4    Zhou, L.5    Fung, K.P.6    Wu, P.7    Wu, S.8
  • 28
    • 69949122837 scopus 로고    scopus 로고
    • Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway
    • J.Z. Shan, Y.Y. Xuan, S. Zheng, Q. Dong, and S.Z. Zhang Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway J. Zhejiang. Univ. Sci. B. 10 2009 668 674
    • (2009) J. Zhejiang. Univ. Sci. B. , vol.10 , pp. 668-674
    • Shan, J.Z.1    Xuan, Y.Y.2    Zheng, S.3    Dong, Q.4    Zhang, S.Z.5
  • 29
    • 0026559650 scopus 로고
    • Characterization of ursolic acid as a lipoxygenase and cyclooxygenase inhibitor using macrophages, platelets and differentiated HL60 leukemic cells
    • A. Najid, A. Simon, J. Cook, H. Chable-Rabinovitch, C. Delage, A.J. Chulia, and M. Rigaud Characterization of ursolic acid as a lipoxygenase and cyclooxygenase inhibitor using macrophages, platelets and differentiated HL60 leukemic cells FEBS Lett. 299 1992 213 217
    • (1992) FEBS Lett. , vol.299 , pp. 213-217
    • Najid, A.1    Simon, A.2    Cook, J.3    Chable-Rabinovitch, H.4    Delage, C.5    Chulia, A.J.6    Rigaud, M.7
  • 30
    • 0030578756 scopus 로고    scopus 로고
    • Inhibitory effect of ursolic acid on B16 proliferation through cell cycle arrest
    • PII S0304383596043121
    • D. Es-Saady, A. Simon, M. Ollier, J.C. Maurizis, A.J. Chulia, and C. Delage Inhibitory effect of ursolic acid on B16 proliferation through cell cycle arrest Cancer Lett. 106 1996 193 197 (Pubitemid 126745145)
    • (1996) Cancer Letters , vol.106 , Issue.2 , pp. 193-197
    • Es-saady, D.1    Simon, A.2    Ollier, M.3    Maurizis, J.C.4    Chulia, A.J.5    Delage, C.6
  • 31
    • 13244255330 scopus 로고    scopus 로고
    • Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells
    • DOI 10.1002/ijc.20588
    • P.O. Harmand, R. Duval, C. Delage, and A. Simon Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells Int. J. Cancer 114 2005 1 11 (Pubitemid 40194303)
    • (2005) International Journal of Cancer , vol.114 , Issue.1 , pp. 1-11
    • Harmand, P.-O.1    Duval, R.2    Delage, C.3    Simon, A.4
  • 32
  • 33
    • 33748547765 scopus 로고    scopus 로고
    • Low dose leflunomide activates PI3K/Akt signalling in erythroleukemia cells and reduces apoptosis induced by anticancer agents
    • DOI 10.1007/s10495-006-9439-7
    • D.Y. Leger, B. Liagre, and J.L. Beneytout Low dose leflunomide activates PI3K/Akt signaling in erythroleukemia cells and reduces apoptosis induced by anticancer agents Apoptosis 11 2006 1747 1760 (Pubitemid 44371050)
    • (2006) Apoptosis , vol.11 , Issue.10 , pp. 1747-1760
    • Leger, D.Y.1    Liagre, B.2    Beneytout, J.L.3
  • 34
    • 0033957363 scopus 로고    scopus 로고
    • A cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug enhances the growth inhibitory effect of butyrate in colorectal carcinoma cells expressing COX-2 protein: Regulation of COX-2 by butyrate
    • T.E. Crew, D.J. Elder, and C. Paraskeva A cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug enhances the growth inhibitory effect of butyrate in colorectal carcinoma cells expressing COX-2 protein: regulation of COX-2 by butyrate Carcinogenesis 21 2000 69 77 (Pubitemid 30064146)
    • (2000) Carcinogenesis , vol.21 , Issue.1 , pp. 69-77
    • Crew, T.E.1    Elder, D.J.E.2    Paraskeva, C.3
  • 35
    • 58949094558 scopus 로고    scopus 로고
    • Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death
    • Y. Sun, J. Chen, and B. Rigas Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death Carcinogenesis 30 2009 93 100
    • (2009) Carcinogenesis , vol.30 , pp. 93-100
    • Sun, Y.1    Chen, J.2    Rigas, B.3
  • 36
    • 0141539530 scopus 로고    scopus 로고
    • Review article: Mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease
    • H. Allgayer Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease Aliment. Pharmacol. Ther. 18 Suppl. 2 2003 10 14 (Pubitemid 37174711)
    • (2003) Alimentary Pharmacology and Therapeutics, Supplement , vol.18 , Issue.2 , pp. 10-14
    • Allgayer, H.1
  • 37
    • 67650270892 scopus 로고    scopus 로고
    • Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells
    • E. Looby, M.M. bdel-Latif, V. thie-Morales, S. Duggan, A. Long, and D. Kelleher Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells BMC. Cancer 9 2009 190
    • (2009) BMC. Cancer , vol.9 , pp. 190
    • Looby, E.1    Bdel-Latif, M.M.2    Thie-Morales, V.3    Duggan, S.4    Long, A.5    Kelleher, D.6
  • 38
    • 0034725709 scopus 로고    scopus 로고
    • MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells
    • DOI 10.1074/jbc.M910237199
    • T. Yang, Y. Huang, L.E. Heasley, T. Berl, J.B. Schnermann, and J.P. Briggs MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells J. Biol. Chem. 275 2000 23281 23286 (Pubitemid 30646228)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.30 , pp. 23281-23286
    • Yang, T.1    Huang, Y.2    Heasley, L.E.3    Berl, T.4    Schnermann, J.B.5    Briggs, J.P.6
  • 39
    • 1242314857 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in colorectal cancer
    • DOI 10.1023/A:1025863029529
    • F.A. Sinicrope, and S. Gill Role of cyclooxygenase-2 in colorectal cancer Cancer Metastasis Rev. 23 2004 63 75 (Pubitemid 38221596)
    • (2004) Cancer and Metastasis Reviews , vol.23 , Issue.1-2 , pp. 63-75
    • Sinicrope, F.A.1    Gill, S.2
  • 42
    • 0028261042 scopus 로고
    • 2
    • S. Pugh, and G.A. Thomas Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2 Gut 35 1994 675 678 (Pubitemid 24163797)
    • (1994) Gut , vol.35 , Issue.5 , pp. 675-678
    • Pugh, S.1    Thomas, G.A.O.2
  • 45
    • 0037057340 scopus 로고    scopus 로고
    • The role of p38 in UVA-induced cyclooxygenase-2 expression in the human keratinocyte cell line, HaCaT
    • DOI 10.1038/sj.onc.1205855
    • M.A. Bachelor, A.L. Silvers, and G.T. Bowden The role of p38 in UVA-induced cyclooxygenase-2 expression in the human keratinocyte cell line, HaCaT Oncogene 21 2002 7092 7099 (Pubitemid 35252983)
    • (2002) Oncogene , vol.21 , Issue.46 , pp. 7092-7099
    • Bachelor, M.A.1    Silvers, A.L.2    Bowden, G.T.3
  • 46
    • 0032951716 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
    • DOI 10.1074/jbc.274.1.264
    • J.L. Dean, M. Brook, A.R. Clark, and J. Saklatvala p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes J. Biol. Chem. 274 1999 264 269 (Pubitemid 29035058)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.1 , pp. 264-269
    • Dean, J.L.E.1    Brook, M.2    Clark, A.R.3    Saklatvala, J.4
  • 47
    • 0034077529 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase 2 mRNA stability by the mitogen- activated protein kinase p38 signaling cascade
    • DOI 10.1128/MCB.20.12.4265-4274.2000
    • M. Lasa, K.R. Mahtani, A. Finch, G. Brewer, J. Saklatvala, and A.R. Clark Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade Mol. Cell Biol. 20 2000 4265 4274 (Pubitemid 30346621)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.12 , pp. 4265-4274
    • Lasa, M.1    Mahtani, K.R.2    Finch, A.3    Brewer, G.4    Saklatvala, J.5    Clark, A.R.6
  • 48
    • 0032515186 scopus 로고    scopus 로고
    • A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA
    • DOI 10.1016/S0014-5793(98)01342-8, PII S0014579398013428
    • S.H. Ridley, J.L. Dean, S.J. Sarsfield, M. Brook, A.R. Clark, and J. Saklatvala A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA FEBS Lett. 439 1998 75 80 (Pubitemid 28537867)
    • (1998) FEBS Letters , vol.439 , Issue.1-2 , pp. 75-80
    • Ridley, S.H.1    Dean, J.L.E.2    Sarsfield, S.J.3    Brook, M.4    Clark, A.R.5    Saklatvala, J.6
  • 49
    • 0034489934 scopus 로고    scopus 로고
    • Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells
    • Z. Zhang, H. Sheng, J. Shao, R.D. Beauchamp, and R.N. DuBois Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells Neoplasia 2 2000 523 530 (Pubitemid 32098687)
    • (2000) Neoplasia , vol.2 , Issue.6 , pp. 523-530
    • Zhang, Z.1    Sheng, H.2    Shao, J.3    Beauchampt, R.D.4    DuBois, R.N.5
  • 52
    • 0033607519 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 induces cell cycle arrest: Evidence for a prostaglandin-independent mechanism
    • O.C. Trifan, R.M. Smith, B.D. Thompson, and T. Hla Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin- independent mechanism J. Biol. Chem. 274 1999 34141 34147 (Pubitemid 129511751)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.48 , pp. 34141-34147
    • Trifan, O.C.1    Smith, R.M.2    Thompson, B.D.3    Hla, T.4
  • 53
    • 0037155787 scopus 로고    scopus 로고
    • kip-1
    • DOI 10.1074/jbc.M106307200
    • G. Zahner, G. Wolf, M. Ayoub, R. Reinking, U. Panzer, S.J. Shankland, and R.A. Stahl Cyclooxygenase-2 overexpression inhibits platelet-derived growth factor-induced mesangial cell proliferation through induction of the tumor suppressor gene p53 and the cyclin-dependent kinase inhibitors p21waf-1/cip-1 and p27kip-1 J. Biol. Chem. 277 2002 9763 9771 (Pubitemid 34968079)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.12 , pp. 9763-9771
    • Zahner, G.1    Wolf, G.2    Ayoub, M.3    Reinking, R.4    Panzer, U.5    Shankland, S.J.6    Stahl, R.A.K.7
  • 54
    • 0019986220 scopus 로고
    • Effects of non-steroidal anti-inflammatory drugs on fatty acid cyclooxygenase and prostaglandin hydroperoxidase activities
    • K. Mizuno, S. Yamamoto, and W.E. Lands Effects of non-steroidal anti-inflammatory drugs on fatty acid cyclooxygenase and prostaglandin hydroperoxidase activities Prostaglandins 23 1982 743 757 (Pubitemid 12046653)
    • (1982) Prostaglandins , vol.23 , Issue.5 , pp. 743-757
    • Mizuno, K.1    Yamamoto, S.2    Lands, W.E.M.3
  • 55
    • 0037898985 scopus 로고    scopus 로고
    • Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases
    • C.A. Rouzer, and L.J. Marnett Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases Chem. Rev. 103 2003 2239 2304
    • (2003) Chem. Rev. , vol.103 , pp. 2239-2304
    • Rouzer, C.A.1    Marnett, L.J.2
  • 56
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • DOI 10.1136/gut.2004.047100
    • D. Wang, and R.N. DuBois Prostaglandins and cancer Gut 55 2006 115 122 (Pubitemid 41820645)
    • (2006) Gut , vol.55 , Issue.1 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.