메뉴 건너뛰기




Volumn 5, Issue 11, 2010, Pages

ER-α36, a novel variant of ER-α, mediates estrogen stimulated proliferation of endometrial carcinoma cells via the PKCδ/ERK pathway

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BISINDOLYLMALEIMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA 36; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C DELTA; ROTTLERIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; BOVINE SERUM ALBUMIN; ISOPROTEIN;

EID: 78149476449     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015408     Document Type: Article
Times cited : (67)

References (53)
  • 1
    • 33646371740 scopus 로고    scopus 로고
    • Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis
    • Shang Y (2006) Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis. Nat Rev Cancer 6: 360-368.
    • (2006) Nat Rev Cancer , vol.6 , pp. 360-368
    • Shang, Y.1
  • 2
    • 67650469833 scopus 로고    scopus 로고
    • Resistance to chemotherapy and hormone therapy in endometrial cancer
    • Chaudhry P, Asselin E (2009) Resistance to chemotherapy and hormone therapy in endometrial cancer. Endocr Relat Cancer 16: 363-380.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 363-380
    • Chaudhry, P.1    Asselin, E.2
  • 4
    • 0034595096 scopus 로고    scopus 로고
    • Estrogen receptors: How do they control reproductive and nonreproductive functions?
    • Muramatsu M, Inoue S (2000) Estrogen receptors: how do they control reproductive and nonreproductive functions? Biochem Biophys Res Commun 270: 1-10.
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 1-10
    • Muramatsu, M.1    Inoue, S.2
  • 5
    • 0037360318 scopus 로고    scopus 로고
    • Role of phosphatase PTEN in the activation of extracellular signal-regulated kinases induced by estradiol in endometrial carcinoma cells
    • Zhang Y, Wei L, Wang J, Sun T (2003) Role of phosphatase PTEN in the activation of extracellular signal-regulated kinases induced by estradiol in endometrial carcinoma cells. Chin Med J (Engl) 116: 383-387.
    • (2003) Chin Med J (Engl) , vol.116 , pp. 383-387
    • Zhang, Y.1    Wei, L.2    Wang, J.3    Sun, T.4
  • 6
    • 0035813090 scopus 로고    scopus 로고
    • Coregulator codes of transcriptional regulation by nuclear receptors
    • Rosenfeld MG, Glass CK (2001) Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem 276: 36865-36868.
    • (2001) J Biol Chem , vol.276 , pp. 36865-36868
    • Rosenfeld, M.G.1    Glass, C.K.2
  • 7
    • 11144332004 scopus 로고    scopus 로고
    • Palmitoylation-dependent estrogen receptor alpha membrane localization: Regulation by 17beta-estradiol
    • Acconcia F, Ascenzi P, Bocedi A, Spisni E, Tomasi V, et al. (2005) Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol. Mol Biol Cell 16: 231-237.
    • (2005) Mol Biol Cell , vol.16 , pp. 231-237
    • Acconcia, F.1    Ascenzi, P.2    Bocedi, A.3    Spisni, E.4    Tomasi, V.5
  • 8
    • 25644437706 scopus 로고    scopus 로고
    • Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66
    • Wang Z, Zhang X, Shen P, Loggie BW, Chang Y, et al. (2005) Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66. Biochem Biophys Res Commun 336: 1023-1027.
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 1023-1027
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5
  • 9
    • 0030987070 scopus 로고    scopus 로고
    • Regulation of protein kinase C
    • Newton AC (1997) Regulation of protein kinase C. Curr Opin Cell Biol 9: 161-167.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 161-167
    • Newton, A.C.1
  • 10
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka Y (1986) Studies and perspectives of protein kinase C. Science 233: 305-312.
    • (1986) Science , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 11
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y (1988) The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334: 661-665.
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 12
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y (1995) Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9: 484-496.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 13
    • 0034194092 scopus 로고    scopus 로고
    • Identification of PKC-isoform-specific biological actions using pharmacological approaches
    • Way KJ, Chou E, King GL (2000) Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol Sci 21: 181-187.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 181-187
    • Way, K.J.1    Chou, E.2    King, G.L.3
  • 14
    • 0037734126 scopus 로고    scopus 로고
    • Estrogendependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membranemediated and inhibited by tamoxifen
    • Boyan BD, Sylvia VL, Frambach T, Lohmann CH, Dietl J, et al. (2003) Estrogendependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membranemediated and inhibited by tamoxifen. Endocrinology 144: 1812-1824.
    • (2003) Endocrinology , vol.144 , pp. 1812-1824
    • Boyan, B.D.1    Sylvia, V.L.2    Frambach, T.3    Lohmann, C.H.4    Dietl, J.5
  • 15
    • 33745160700 scopus 로고    scopus 로고
    • A variant of estrogen receptor-{alpha}, hER-{alpha}36: Transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling
    • Wang Z, Zhang X, Shen P, Loggie BW, Chang Y, et al. (2006) A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling. Proc Natl Acad Sci U S A 103: 9063-9068.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9063-9068
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5
  • 16
    • 33344461590 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
    • Vivacqua A, Bonofiglio D, Recchia AG, Musti AM, Picard D, et al. (2006) The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol Endocrinol 20: 631-646.
    • (2006) Mol Endocrinol , vol.20 , pp. 631-646
    • Vivacqua, A.1    Bonofiglio, D.2    Recchia, A.G.3    Musti, A.M.4    Picard, D.5
  • 17
    • 70449513386 scopus 로고    scopus 로고
    • A novel variant of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cells
    • Lin SL, Yan LY, Liang XW, Wang ZB, Wang ZY, et al. (2009) A novel variant of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cells. Reprod Biol Endocrinol 7: 102.
    • (2009) Reprod Biol Endocrinol , vol.7 , pp. 102
    • Lin, S.L.1    Yan, L.Y.2    Liang, X.W.3    Wang, Z.B.4    Wang, Z.Y.5
  • 18
    • 0036214877 scopus 로고    scopus 로고
    • Expression of cyclin D1 in normal, metaplastic, hyperplastic endometrium and endometrioid carcinoma suggests a role in endometrial carcinogenesis
    • Ruhul Quddus M, Latkovich P, Castellani WJ, James Sung C, Steinhoff MM, et al. (2002) Expression of cyclin D1 in normal, metaplastic, hyperplastic endometrium and endometrioid carcinoma suggests a role in endometrial carcinogenesis. Arch Pathol Lab Med 126: 459-463.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 459-463
    • Ruhul Quddus, M.1    Latkovich, P.2    Castellani, W.J.3    James Sung, C.4    Steinhoff, M.M.5
  • 19
    • 65549133791 scopus 로고    scopus 로고
    • Autocrine stimulation of IGF1 in estrogen-induced growth of endometrial carcinoma cells: Involvement of the mitogen-activated protein kinase pathway followed by up-regulation of cyclin D1 and cyclin
    • Kashima H, Shiozawa T, Miyamoto T, Suzuki A, Uchikawa J, et al. (2009) Autocrine stimulation of IGF1 in estrogen-induced growth of endometrial carcinoma cells: involvement of the mitogen-activated protein kinase pathway followed by up-regulation of cyclin D1 and cyclin E. Endocr Relat Cancer 16: 113-122.
    • (2009) E. Endocr Relat Cancer , vol.16 , pp. 113-122
    • Kashima, H.1    Shiozawa, T.2    Miyamoto, T.3    Suzuki, A.4    Uchikawa, J.5
  • 21
    • 33751182887 scopus 로고    scopus 로고
    • Cyclin D1 and breast cancer
    • Roy PG, Thompson AM (2006) Cyclin D1 and breast cancer. Breast 15: 718-727.
    • (2006) Breast , vol.15 , pp. 718-727
    • Roy, P.G.1    Thompson, A.M.2
  • 22
    • 33846066888 scopus 로고    scopus 로고
    • Estrogen signaling multiple pathways to impact gene transcription
    • Marino M, Galluzzo P, Ascenzi P (2006) Estrogen signaling multiple pathways to impact gene transcription. Curr Genomics 7: 497-508.
    • (2006) Curr Genomics , vol.7 , pp. 497-508
    • Marino, M.1    Galluzzo, P.2    Ascenzi, P.3
  • 23
    • 66749105045 scopus 로고    scopus 로고
    • Nuclear receptors: Genomic and nongenomic effects converge
    • Ordonez-Moran P, Munoz A (2009) Nuclear receptors: genomic and nongenomic effects converge. Cell Cycle 8: 1675-1680.
    • (2009) Cell Cycle , vol.8 , pp. 1675-1680
    • Ordonez-Moran, P.1    Munoz, A.2
  • 24
    • 64049115275 scopus 로고    scopus 로고
    • Estrogen receptor-alpha (ER-alpha) suppresses expression of its variant ER-alpha 36
    • Zou Y, Ding L, Coleman M, Wang Z (2009) Estrogen receptor-alpha (ER-alpha) suppresses expression of its variant ER-alpha 36. FEBS Lett 583: 1368-1374.
    • (2009) FEBS Lett , vol.583 , pp. 1368-1374
    • Zou, Y.1    Ding, L.2    Coleman, M.3    Wang, Z.4
  • 25
    • 77749252827 scopus 로고    scopus 로고
    • ER-alpha36, a variant of ERalpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways
    • Lin SL, Yan LY, Zhang XT, Yuan J, Li M, et al. ER-alpha36, a variant of ERalpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways. PLoS One 5: e9013.
    • PLoS One , vol.5
    • Lin, S.L.1    Yan, L.Y.2    Zhang, X.T.3    Yuan, J.4    Li, M.5
  • 26
    • 34247895595 scopus 로고    scopus 로고
    • G proteincoupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after traumahemorrhage
    • Hsieh YC, Yu HP, Frink M, Suzuki T, Choudhry MA, et al. (2007) G proteincoupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after traumahemorrhage. Am J Pathol 170: 1210-1218.
    • (2007) Am J Pathol , vol.170 , pp. 1210-1218
    • Hsieh, Y.C.1    Yu, H.P.2    Frink, M.3    Suzuki, T.4    Choudhry, M.A.5
  • 27
    • 49549099539 scopus 로고    scopus 로고
    • 17beta-estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKAErk- dependent pathway in the human eccrine sweat gland cell line NCL-SG3
    • Muchekehu RW, Harvey BJ (2008) 17beta-estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKAErk- dependent pathway in the human eccrine sweat gland cell line NCL-SG3. Cell Calcium 44: 276-288.
    • (2008) Cell Calcium , vol.44 , pp. 276-288
    • Muchekehu, R.W.1    Harvey, B.J.2
  • 28
    • 33745167352 scopus 로고    scopus 로고
    • 17 beta-estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells
    • Guo RX, Wei LH, Tu Z, Sun PM, Wang JL, et al. (2006) 17 beta-estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells. J Steroid Biochem Mol Biol 99: 9-18.
    • (2006) J Steroid Biochem Mol Biol , vol.99 , pp. 9-18
    • Guo, R.X.1    Wei, L.H.2    Tu, Z.3    Sun, P.M.4    Wang, J.L.5
  • 29
    • 0032853929 scopus 로고    scopus 로고
    • Estrogen hits the surface
    • Collins P, Webb C (1999) Estrogen hits the surface. Nat Med 5: 1130-1131.
    • (1999) Nat Med , vol.5 , pp. 1130-1131
    • Collins, P.1    Webb, C.2
  • 30
    • 0032714108 scopus 로고    scopus 로고
    • Membrane oestrogen receptors on rat pituitary tumour cells: Immuno-identification and responses to oestradiol and xenoestrogens
    • Watson CS, Campbell CH, Gametchu B (1999) Membrane oestrogen receptors on rat pituitary tumour cells: immuno-identification and responses to oestradiol and xenoestrogens. Exp Physiol 84: 1013-1022.
    • (1999) Exp Physiol , vol.84 , pp. 1013-1022
    • Watson, C.S.1    Campbell, C.H.2    Gametchu, B.3
  • 31
    • 62649130173 scopus 로고    scopus 로고
    • Nongenomic effect of estrogen on the MAPK signaling pathway and calcium influx in endometrial carcinoma cells
    • Zhang L, Li X, Zhao L, Zhang G, Wang J, et al. (2009) Nongenomic effect of estrogen on the MAPK signaling pathway and calcium influx in endometrial carcinoma cells. J Cell Biochem 106: 553-562.
    • (2009) J Cell Biochem , vol.106 , pp. 553-562
    • Zhang, L.1    Li, X.2    Zhao, L.3    Zhang, G.4    Wang, J.5
  • 32
    • 0037053308 scopus 로고    scopus 로고
    • Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta
    • Deucher A, Efimova T, Eckert RL (2002) Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta. J Biol Chem 277: 17032-17040.
    • (2002) J Biol Chem , vol.277 , pp. 17032-17040
    • Deucher, A.1    Efimova, T.2    Eckert, R.L.3
  • 33
    • 36749025313 scopus 로고    scopus 로고
    • Protein kinase Cdelta and apoptosis
    • Reyland ME (2007) Protein kinase Cdelta and apoptosis. Biochem Soc Trans 35: 1001-1004.
    • (2007) Biochem Soc Trans , vol.35 , pp. 1001-1004
    • Reyland, M.E.1
  • 34
    • 0037246123 scopus 로고    scopus 로고
    • Regulation of cell apoptosis by protein kinase c delta
    • Brodie C, Blumberg PM (2003) Regulation of cell apoptosis by protein kinase c delta. Apoptosis 8: 19-27.
    • (2003) Apoptosis , vol.8 , pp. 19-27
    • Brodie, C.1    Blumberg, P.M.2
  • 35
    • 0036076333 scopus 로고    scopus 로고
    • FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway
    • Liu JF, Crepin M, Liu JM, Barritault D, Ledoux D (2002) FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway. Biochem Biophys Res Commun 293: 1174-1182.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 1174-1182
    • Liu, J.F.1    Crepin, M.2    Liu, J.M.3    Barritault, D.4    Ledoux, D.5
  • 37
    • 0031684848 scopus 로고    scopus 로고
    • Protein kinase Cdelta is an important signaling molecule in insulin-like growth factor I receptormediated cell transformation
    • Li W, Jiang YX, Zhang J, Soon L, Flechner L, et al. (1998) Protein kinase Cdelta is an important signaling molecule in insulin-like growth factor I receptormediated cell transformation. Mol Cell Biol 18: 5888-5898.
    • (1998) Mol Cell Biol , vol.18 , pp. 5888-5898
    • Li, W.1    Jiang, Y.X.2    Zhang, J.3    Soon, L.4    Flechner, L.5
  • 38
    • 0032741145 scopus 로고    scopus 로고
    • Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells
    • Sinha R, Kiley SC, Lu JX, Thompson HJ, Moraes R, et al. (1999) Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells. Cancer Lett 146: 135-145.
    • (1999) Cancer Lett , vol.146 , pp. 135-145
    • Sinha, R.1    Kiley, S.C.2    Lu, J.X.3    Thompson, H.J.4    Moraes, R.5
  • 39
    • 33645845151 scopus 로고    scopus 로고
    • Protein kinase C (PKC) family in cancer progression
    • Koivunen J, Aaltonen V, Peltonen J (2006) Protein kinase C (PKC) family in cancer progression. Cancer Lett 235: 1-10.
    • (2006) Cancer Lett , vol.235 , pp. 1-10
    • Koivunen, J.1    Aaltonen, V.2    Peltonen, J.3
  • 40
    • 4143112597 scopus 로고    scopus 로고
    • Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells
    • Koivunen J, Aaltonen V, Koskela S, Lehenkari P, Laato M, et al. (2004) Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells. Cancer Res 64: 5693-5701.
    • (2004) Cancer Res , vol.64 , pp. 5693-5701
    • Koivunen, J.1    Aaltonen, V.2    Koskela, S.3    Lehenkari, P.4    Laato, M.5
  • 41
    • 0242406701 scopus 로고    scopus 로고
    • Cell growth inhibition by all-trans retinoic acid in SKBR-3 breast cancer cells: Involvement of protein kinase Calpha and extracellular signal-regulated kinase mitogen-activated protein kinase
    • Nakagawa S, Fujii T, Yokoyama G, Kazanietz MG, Yamana H, et al. (2003) Cell growth inhibition by all-trans retinoic acid in SKBR-3 breast cancer cells: involvement of protein kinase Calpha and extracellular signal-regulated kinase mitogen-activated protein kinase. Mol Carcinog 38: 106-116.
    • (2003) Mol Carcinog , vol.38 , pp. 106-116
    • Nakagawa, S.1    Fujii, T.2    Yokoyama, G.3    Kazanietz, M.G.4    Yamana, H.5
  • 42
    • 4143099402 scopus 로고    scopus 로고
    • Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis
    • Jiang XH, Tu SP, Cui JT, Lin MC, Xia HH, et al. (2004) Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis. Cancer Res 64: 5787-5794.
    • (2004) Cancer Res , vol.64 , pp. 5787-5794
    • Jiang, X.H.1    Tu, S.P.2    Cui, J.T.3    Lin, M.C.4    Xia, H.H.5
  • 43
    • 0032990503 scopus 로고    scopus 로고
    • Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells
    • Leirdal M, Sioud M (1999) Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells. Br J Cancer 80: 1558-1564.
    • (1999) Br J Cancer , vol.80 , pp. 1558-1564
    • Leirdal, M.1    Sioud, M.2
  • 44
    • 0037229883 scopus 로고    scopus 로고
    • Nongenomic activity and subsequent c-fos induction by estrogen receptor ligands are not sufficient to promote deoxyribonucleic acid synthesis in human endometrial adenocarcinoma cells
    • Singleton DW, Feng Y, Burd CJ, Khan SA (2003) Nongenomic activity and subsequent c-fos induction by estrogen receptor ligands are not sufficient to promote deoxyribonucleic acid synthesis in human endometrial adenocarcinoma cells. Endocrinology 144: 121-128.
    • (2003) Endocrinology , vol.144 , pp. 121-128
    • Singleton, D.W.1    Feng, Y.2    Burd, C.J.3    Khan, S.A.4
  • 45
    • 0036297814 scopus 로고    scopus 로고
    • Membrane association of estrogen receptor alpha mediates estrogen effect on MAPK activation
    • Zhang Z, Maier B, Santen RJ, Song RX (2002) Membrane association of estrogen receptor alpha mediates estrogen effect on MAPK activation. Biochem Biophys Res Commun 294: 926-933.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 926-933
    • Zhang, Z.1    Maier, B.2    Santen, R.J.3    Song, R.X.4
  • 46
    • 0036137605 scopus 로고    scopus 로고
    • Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation
    • Song RX, McPherson RA, Adam L, Bao Y, Shupnik M, et al. (2002) Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation. Mol Endocrinol 16: 116-127.
    • (2002) Mol Endocrinol , vol.16 , pp. 116-127
    • Song, R.X.1    McPherson, R.A.2    Adam, L.3    Bao, Y.4    Shupnik, M.5
  • 47
    • 0029789967 scopus 로고    scopus 로고
    • Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
    • Ueda Y, Hirai S, Osada S, Suzuki A, Mizuno K, et al. (1996) Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J Biol Chem 271: 23512-23519.
    • (1996) J Biol Chem , vol.271 , pp. 23512-23519
    • Ueda, Y.1    Hirai, S.2    Osada, S.3    Suzuki, A.4    Mizuno, K.5
  • 48
    • 0027956113 scopus 로고
    • Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2
    • Qiu ZH, Leslie CC (1994) Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2. J Biol Chem 269: 19480-19487.
    • (1994) J Biol Chem , vol.269 , pp. 19480-19487
    • Qiu, Z.H.1    Leslie, C.C.2
  • 49
    • 0032493489 scopus 로고    scopus 로고
    • Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells
    • Knudsen KE, Arden KC, Cavenee WK (1998) Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells. J Biol Chem 273: 20213-20222.
    • (1998) J Biol Chem , vol.273 , pp. 20213-20222
    • Knudsen, K.E.1    Arden, K.C.2    Cavenee, W.K.3
  • 50
    • 0027293137 scopus 로고
    • Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
    • Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, et al. (1993) Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev 7: 1559-1571.
    • (1993) Genes Dev , vol.7 , pp. 1559-1571
    • Quelle, D.E.1    Ashmun, R.A.2    Shurtleff, S.A.3    Kato, J.Y.4    Bar-Sagi, D.5
  • 51
    • 0036203143 scopus 로고    scopus 로고
    • Expression of COX-2, Ki-67, cyclin D1, and P21 in endometrial endometrioid carcinomas
    • Cao QJ, Einstein MH, Anderson PS, Runowicz CD, Balan R, et al. (2002) Expression of COX-2, Ki-67, cyclin D1, and P21 in endometrial endometrioid carcinomas. Int J Gynecol Pathol 21: 147-154.
    • (2002) Int J Gynecol Pathol , vol.21 , pp. 147-154
    • Cao, Q.J.1    Einstein, M.H.2    Anderson, P.S.3    Runowicz, C.D.4    Balan, R.5
  • 52
    • 75949110752 scopus 로고    scopus 로고
    • ERK activation and cell growth require CaM kinases in MCF-7 breast cancer cells
    • Schmitt JM, Abell E, Wagner A, Davare MA () ERK activation and cell growth require CaM kinases in MCF-7 breast cancer cells. Mol Cell Biochem 335: 155-171.
    • Mol Cell Biochem , vol.335 , pp. 155-171
    • Schmitt, J.M.1    Abell, E.2    Wagner, A.3    Davare, M.A.4
  • 53
    • 9644303358 scopus 로고    scopus 로고
    • Estrogen-induced proliferation of normal endometrial glandular cells is initiated by transcriptional activation of cyclin D1 via binding of c-Jun to an AP-1 sequence
    • Shiozawa T, Miyamoto T, Kashima H, Nakayama K, Nikaido T, et al. (2004) Estrogen-induced proliferation of normal endometrial glandular cells is initiated by transcriptional activation of cyclin D1 via binding of c-Jun to an AP-1 sequence. Oncogene 23: 8603-8610.
    • (2004) Oncogene , vol.23 , pp. 8603-8610
    • Shiozawa, T.1    Miyamoto, T.2    Kashima, H.3    Nakayama, K.4    Nikaido, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.