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Volumn 2, Issue 3, 2010, Pages 1629-1641

Cancer stem cells in pancreatic cancer

Author keywords

Cancer stem cells; CSC related therapy; Metastasis; microRNAs; Pancreatic cancer; Signaling pathways

Indexed keywords

ALCOHOL DEHYDROGENASE; ANTAGOMIR 10B; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BMI1 PROTEIN; CD133 ANTIGEN; CD24 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; EPITHELIAL CELL ADHESION MOLECULE; FLUOROURACIL; GEMCITABINE; HERMES ANTIGEN; MICRORNA; MICRORNA 21; SMALL INTERFERING RNA; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

EID: 79952275610     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers2031629     Document Type: Review
Times cited : (22)

References (72)
  • 3
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet, D.; Dick, J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 1997, 3, 730-737.
    • (1997) Nat. Med. , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 5
    • 0036452225 scopus 로고    scopus 로고
    • A fresh perspective
    • Singh, K. A fresh perspective. Proc. Graph. Interf. 2002, 237, 17-24.
    • (2002) Proc. Graph. Interf. , vol.237 , pp. 17-24
    • Singh, K.1
  • 7
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien, C.A. Pollett, A.; Gallinger, S.; Dick, J.E. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007, 445, 106-110.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 8
    • 34249980343 scopus 로고    scopus 로고
    • Identification and characterization of tumorigenic liver cancer stem/progenitor cells
    • Ma, S.; Chan, K.W.; Hu, L.; Lee, T.K.W.; Wo, J.Y.H.; Ng, I.L.; Zheng, B.J.; Guan, X.Y. Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 2007, 132, 2542-2556.
    • (2007) Gastroenterology , vol.132 , pp. 2542-2556
    • Ma, S.1    Chan, K.W.2    Hu, L.3    Lee, T.K.W.4    Wo, J.Y.H.5    Ng, I.L.6    Zheng, B.J.7    Guan, X.Y.8
  • 10
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann, P.C.; Huber, S.L.; Herrler, T.; Aicher, A.; Ellwart, J.W.; Guba, M.; Bruns, C.J.; Heeschen, C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007, 1, 313-323.
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 20
    • 58149506283 scopus 로고    scopus 로고
    • Gli1 is regulated through smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates pdac cell survival and transformation
    • Nolan-Stevaux, O.; Lau, J.; Truitt, M.L.; Chu, G.C.; Hebrok, M.; Fernandez-Zapico, M.E.; Hanahan, D. Gli1 is regulated through smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates pdac cell survival and transformation. Gene Dev. 2009, 23, 24-36.
    • (2009) Gene Dev , vol.23 , pp. 24-36
    • Nolan-Stevaux, O.1    Lau, J.2    Truitt, M.L.3    Chu, G.C.4    Hebrok, M.5    Fernandez-Zapico, M.E.6    Hanahan, D.7
  • 25
    • 77956178360 scopus 로고    scopus 로고
    • Emt, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
    • doi: 10.1038/onc.2010.215
    • Singh, A.; Settleman, J. Emt, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer. Oncogene 2010, doi: 10.1038/onc.2010.215.
    • (2010) Oncogene
    • Singh, A.1    Settleman, J.2
  • 27
    • 0032926177 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for cd44-mediated tumor invasion
    • Yu, Q.; Stamenkovic, I. Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for cd44-mediated tumor invasion. Genes Dev. 1999, 13, 35-48.
    • (1999) Genes Dev , vol.13 , pp. 35-48
    • Yu, Q.1    Stamenkovic, I.2
  • 31
    • 0037115647 scopus 로고    scopus 로고
    • Expression of cxc chemokine receptor-4 enhances the pulmonary metastatic potential of murine b16 melanoma cells
    • Murakami, T.; Maki, W.; Cardones, A.R.; Fang, H.; Tun Kyi, A.; Nestle, F.O.; Hwang, S.T. Expression of cxc chemokine receptor-4 enhances the pulmonary metastatic potential of murine b16 melanoma cells. Cancer Res. 2002, 62, 7328-7334.
    • (2002) Cancer Res , vol.62 , pp. 7328-7334
    • Murakami, T.1    Maki, W.2    Cardones, A.R.3    Fang, H.4    Tun Kyi, A.5    Nestle, F.O.6    Hwang, S.T.7
  • 33
    • 28544440733 scopus 로고    scopus 로고
    • Differential expression of cxcr4 is associated with the metastatic potential of human non-small cell lung cancer cells
    • Su, L.; Zhang, J.; Xu, H.; Wang, Y.; Chu, Y.; Liu, R.; Xiong, S. Differential expression of cxcr4 is associated with the metastatic potential of human non-small cell lung cancer cells. Clin. Cancer Res. 2005, 11, 8273-8280.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 8273-8280
    • Su, L.1    Zhang, J.2    Xu, H.3    Wang, Y.4    Chu, Y.5    Liu, R.6    Xiong, S.7
  • 34
    • 77950819301 scopus 로고    scopus 로고
    • New advances on critical implications of tumor- and metastasisinitiating cells in cancer progression, treatment resistance and disease recurrence
    • Mimeault, M.; Batra, S.K. New advances on critical implications of tumor- and metastasisinitiating cells in cancer progression, treatment resistance and disease recurrence. Histol. Histopathol. 2010, 25, 1057-1073.
    • (2010) Histol. Histopathol. , vol.25 , pp. 1057-1073
    • Mimeault, M.1    Batra, S.K.2
  • 36
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed rnas
    • Lagos-Quintana, M.; Rauhut, R.; Lendeckel, W.; Tuschl, T. Identification of novel genes coding for small expressed rnas. Science 2001, 294, 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 37
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - micrornas with a role in cancer
    • Esquela-Kerscher, A.; Slack, F.J. Oncomirs - micrornas with a role in cancer. Nat. Rev. Cancer 2006, 6, 259-269.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 42
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between zeb1 and members of the mir-200 family promotes emt and invasion in cancer cells
    • Burk, U.; Schubert, J.; Wellner, U.; Schmalhofer, O.; Vincan, E.; Spaderna, S.; Brabletz, T. A reciprocal repression between zeb1 and members of the mir-200 family promotes emt and invasion in cancer cells. EMBO Rep. 2008, 9, 582-589.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 45
    • 34548565806 scopus 로고    scopus 로고
    • Overexpression of the microrna hsa-mir-200c leads to reduced expression of transcription factor 8 and increased expression of e-cadherin
    • Hurteau, G.J.; Carlson, J.A.; Spivack, S.D.; Brock, G.J. Overexpression of the microrna hsa-mir-200c leads to reduced expression of transcription factor 8 and increased expression of e-cadherin. Cancer Res. 2007, 67, 7972-7976.
    • (2007) Cancer Res , vol.67 , pp. 7972-7976
    • Hurteau, G.J.1    Carlson, J.A.2    Spivack, S.D.3    Brock, G.J.4
  • 46
    • 47249091921 scopus 로고    scopus 로고
    • The mir-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of e-cadherin transcriptional repressors zeb1 and zeb2
    • Korpal, M.; Lee, E.S.; Hu, G.; Kang, Y. The mir-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of e-cadherin transcriptional repressors zeb1 and zeb2. J Biol Chem 2008, 283, 14910-14914.
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 47
    • 41649091906 scopus 로고    scopus 로고
    • The mir-200 family determines the epithelial phenotype of cancer cells by targeting the e-cadherin repressors zeb1 and zeb2
    • Park, S.M.; Gaur, A.B.; Lengyel, E.; Peter, M.E. The mir-200 family determines the epithelial phenotype of cancer cells by targeting the e-cadherin repressors zeb1 and zeb2. Genes Dev. 2008, 22, 894-907.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 48
    • 53949090314 scopus 로고    scopus 로고
    • Restoration of tumor suppressor mir-34 inhibits human p53-mutant gastric cancer tumorspheres
    • Ji, Q.; Hao, X.; Meng, Y.; Zhang, M.; Desano, J.; Fan, D.; Xu, L. Restoration of tumor suppressor mir-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 2008, 8, 266.
    • (2008) BMC Cancer , vol.8 , pp. 266
    • Ji, Q.1    Hao, X.2    Meng, Y.3    Zhang, M.4    Desano, J.5    Fan, D.6    Xu, L.7
  • 49
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of micrornas by p53 revealed by massively parallel sequencing - mir-34a is a p53 target that induces apoptosis and g(1)-arrest
    • Tarasov, V.; Jung, P.; Verdoodt, B.; Lodygin, D.; Epanchintsev, A.; Menssen, A.; Meister, G.; Hermeking, H. Differential regulation of micrornas by p53 revealed by massively parallel sequencing - mir-34a is a p53 target that induces apoptosis and g(1)-arrest. Cell Cycle 2007, 6, 1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6    Meister, G.7    Hermeking, H.8
  • 57
    • 53249113793 scopus 로고    scopus 로고
    • Pancreatic cancer stem cells: Implications for the treatment of pancreatic cancer
    • Simeone, D.M. Pancreatic cancer stem cells: Implications for the treatment of pancreatic cancer. Clin. Cancer Res. 2008, 14, 5646-5648.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5646-5648
    • Simeone, D.M.1
  • 58
    • 57349147100 scopus 로고    scopus 로고
    • Inhibition of src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: An involvement of epidermal growth factor receptor signaling
    • Ischenko, I.; Camaj, P.; Seeliger, H.; Kleespies, A.; Guba, M.; De Toni, E.N.; Schwarz, B.; Graeb, C.; Eichhorn, M.E.; Jauch, K.W.; Bruns, C.J. Inhibition of src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: An involvement of epidermal growth factor receptor signaling. Oncogene 2008, 27, 7212-7222.
    • (2008) Oncogene , vol.27 , pp. 7212-7222
    • Ischenko, I.1    Camaj, P.2    Seeliger, H.3    Kleespies, A.4    Guba, M.5    de Toni, E.N.6    Schwarz, B.7    Graeb, C.8    Eichhorn, M.E.9    Jauch, K.W.10    Bruns, C.J.11
  • 59
  • 60
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the atp binding cassette (abc) family: An overview
    • Schinkel, A.H.; Jonker, J.W. Mammalian drug efflux transporters of the atp binding cassette (abc) family: An overview. Adv. Drug Deliv. Rev. 2003, 55, 3-29.
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 62
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo, M. Pancreatic cancer. N. Engl. J. Med. 2010, 362, 1605-1617.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 63
    • 68049139572 scopus 로고    scopus 로고
    • Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells
    • Xiong, Y.Q.; Sun, H.C.; Zhang, W.; Zhu, X.D.; Zhuang, P.Y.; Zhang, J.B.; Wang, L.; Wu, W.Z.; Qin, L.X.; Tang, Z.Y. Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Clin. Cancer Res. 2009, 15, 4838-4846.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 4838-4846
    • Xiong, Y.Q.1    Sun, H.C.2    Zhang, W.3    Zhu, X.D.4    Zhuang, P.Y.5    Zhang, J.B.6    Wang, L.7    Wu, W.Z.8    Qin, L.X.9    Tang, Z.Y.10
  • 64
    • 36749090553 scopus 로고    scopus 로고
    • Location, location, location: The cancer stem cell niche
    • Sneddon, J.B.; Werb, Z. Location, location, location: The cancer stem cell niche. Cell Stem Cell 2007, 1, 607-611.
    • (2007) Cell Stem Cell , vol.1 , pp. 607-611
    • Sneddon, J.B.1    Werb, Z.2
  • 65
    • 57049090610 scopus 로고    scopus 로고
    • Microrna-21 is overexpressed in pancreatic cancer and a potential predictor of survival
    • Dillhoff, M.; Liu, J.; Frankel, W.; Croce, C.; Bloomston, M. Microrna-21 is overexpressed in pancreatic cancer and a potential predictor of survival. J. Gastrointest. Surg. 2008, 12, 2171-2176.
    • (2008) J. Gastrointest. Surg. , vol.12 , pp. 2171-2176
    • Dillhoff, M.1    Liu, J.2    Frankel, W.3    Croce, C.4    Bloomston, M.5
  • 67
    • 33645135862 scopus 로고    scopus 로고
    • Anti-mirna oligonucleotides (amos): Ammunition to target mirnas implicated in human disease?
    • Weiler, J.; Hunziker, J.; Hall, J. Anti-mirna oligonucleotides (amos): Ammunition to target mirnas implicated in human disease? Gene Ther. 2006, 13, 496-502.
    • (2006) Gene Ther , vol.13 , pp. 496-502
    • Weiler, J.1    Hunziker, J.2    Hall, J.3
  • 68
    • 33646027887 scopus 로고    scopus 로고
    • Lna-modified oligonucleotides mediate specific inhibition of microrna function
    • Orom, U.A.; Kauppinen, S.; Lund, A.H. Lna-modified oligonucleotides mediate specific inhibition of microrna function. Gene 2006, 372, 137-141.
    • (2006) Gene , vol.372 , pp. 137-141
    • Orom, U.A.1    Kauppinen, S.2    Lund, A.H.3
  • 70
    • 34548316982 scopus 로고    scopus 로고
    • Microrna sponges: Competitive inhibitors of small rnas in mammalian cells
    • Ebert, M.S.; Neilson, J.R.; Sharp, P.A. Microrna sponges: Competitive inhibitors of small rnas in mammalian cells. Nat. Methods 2007, 4, 721-726.
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.