Quantitative proteomic profiling studies of pancreatic cancer stem cells

Journal of Proteome Research

Volumn 9, Issue 7, 2010, Pages 3394-3402

  Dai, Lan ^a   Li, Chen ^b   Shedden, Kerby A ^b   Lee, Cheong J ^c   Li, Chenwei ^c   Quoc, Huyvuong ^a   Simeone, Diane M ^c   Lubman, David M ^a,b,c  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

cancer stem cells; capillary isoelectric focusing; differential expression; pathway analysis; proteome profiling; spectral count; two dimensional separation

Indexed keywords

CELL PROTEIN; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CAPILLARY ISOELECTRIC FOCUSING; CONTROLLED STUDY; DIFFERENTIAL DISPLAY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; CLASSIFICATION; CLUSTER ANALYSIS; DRUG SCREENING; GENE EXPRESSION PROFILING; ISOELECTRIC FOCUSING; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS TUMOR; PROCEDURES; REVERSED PHASE LIQUID CHROMATOGRAPHY; SCID MOUSE; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; CHROMATOGRAPHY, REVERSE-PHASE; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; HUMANS; ISOELECTRIC FOCUSING; MALE; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASTIC STEM CELLS; PANCREATIC NEOPLASMS; PROTEINS; PROTEOMICS; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77954362750     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100231m     Document Type: Article

References (25)

1. Lee, C. J.; Dosch, J.; Simeone, D. M. Pancreatic cancer stem cells J. Clin. Oncol. 2008, 26 (17) 2806-12
2. Li, C.; Heidt, D. G.; Dalerba, P.; Burant, C. F.; Zhang, L.; Adsay, V.; Wicha, M.; Clarke, M. F.; Simeone, D. M. Identification of Pancreatic Cancer Stem Cells Cancer Res. 2007, 67 (3) 1030-1037
3. Fang, X.; Balgley, B. M.; Wang, W.; Park, D. M.; Lee, C. S. Comparison of multidimensional shotgun technologies targeting tissue proteomics Electrophoresis 2009, 30 (23) 4063-70
4. Sodek, K. L.; Evangelou, A. I.; Ignatchenko, A.; Agochiya, M.; Brown, T. J.; Ringuette, M. J.; Jurisica, I.; Kislinger, T. Identification of pathways associated with invasive behavior by ovarian cancer cells using multidimensional protein identification technology (MudPIT) Mol. Biosyst. 2008, 4 (7) 762-73
5. Elschenbroich, S.; Ignatchenko, V.; Sharma, P.; Schmitt-Ulms, G.; Gramolini, A. O.; Kislinger, T. Peptide separations by on-line MudPIT compared to isoelectric focusing in an off-gel format: application to a membrane-enriched fraction from C2C12 mouse skeletal muscle cells J. Proteome Res. 2009, 8 (10) 4860-9
6. Gortzak-Uzan, L.; Ignatchenko, A.; Evangelou, A. I.; Agochiya, M.; Brown, K. A.; St Onge, P.; Kireeva, I.; Schmitt-Ulms, G.; Brown, T. J.; Murphy, J.; Rosen, B.; Shaw, P.; Jurisica, I.; Kislinger, T. A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers J. Proteome Res. 2008, 7 (1) 339-51
7. Hwang, S. I.; Thumar, J.; Lundgren, D. H.; Rezaul, K.; Mayya, V.; Wu, L.; Eng, J.; Wright, M. E.; Han, D. K. Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues Oncogene 2007, 26 (1) 65-76
8. Bagnato, C.; Thumar, J.; Mayya, V.; Hwang, S. I.; Zebroski, H.; Claffey, K. P.; Haudenschild, C.; Eng, J. K.; Lundgren, D. H.; Han, D. K. Proteomics analysis of human coronary atherosclerotic plaque: a feasibility study of direct tissue proteomics by liquid chromatography and tandem mass spectrometry Mol. Cell. Proteomics 2007, 6 (6) 1088-1102
9. Dai, L.; Li, C.; Shedden, K. A.; Misek, D. E.; Lubman, D. M. Comparative proteomic study of two closely related ovarian endometrioid adenocarcinoma cell lines using cIEF fractionation and pathway analysis Electrophoresis 2009, 30 (7) 1119-31
10. Old WM, Meyer-Arendt, K.; Aveline-Wolf, L.; Pierce, K. G.; Mendoza, A.; Sevinsky, J. R.; Resing, K. A.; Ahn, N. G. Comparison of label-free methods for quantifying human proteins by shotgun proteomics Mol. Cell. Proteomics 2005, 4 (10) 1487-502
11. Zybailov, B.; Mosley, A. L.; Sardiu, M. E.; Coleman, M. K.; Florens, L.; Washburn, M. P. Statistical analysis of membrane proteome expression changes in Saccharomyces cerevisiae J. Proteome Res. 2006, 5 (9) 2339-47
12. Choi, H.; Fermin, D.; Nesvizhskii, A. I. Significance analysis of spectral count data in label-free shotgun proteomics Mol. Cell. Proteomics 2008, 7 (12) 2373-85
13. Beissbarth, T.; Hyde, L.; Smyth, G. K.; Job, C.; Boon, W.-M.; Tan, S.-S.; Scott, H. S.; Speed, T. P. Statistical modeling of sequencing errors in SAGE libraries. Bioinformatics 2004, 20, i31-i39
14. Zhuo, L.; Kimata, K. Structure and function of inter-alpha-trypsin inhibitor heavy chains Connect. Tissue Res. 2008, 49 (5) 311-20
15. Kato, M.; Seki, N.; Sugano, S.; Hashimoto, K.; Masuho, Y.; Muramatsu, M.; Kaibuchi, K.; Nakafuku, M. Identification of sonic hedgehog-responsive genes using cDNA microarray Biochem. Biophys. Res. Commun. 2001, 289 (2) 472-8
16. Joza, N.; Susin, S. A.; Daugas, E.; Stanford, W. L.; Cho, S. K.; Li, C. Y.; Sasaki, T.; Elia, A. J.; Cheng, H. Y.; Ravagnan, L.; Ferri, K. F.; Zamzami, N.; Wakeham, A.; Hakem, R.; Yoshida, H.; Kong, Y. Y.; Mak, T. W.; Zga-Pflucker, J. C.; Kroemer, G.; Penninger, J. M. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death Nature 2002, 410 (6828) 549-54
17. Donahue, T. R.; Hines, O. J. CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer World J. Surg. 2009, 33 (4) 710-5
18. Wente, M. N.; Keane, M. P.; Burdick, M. D.; Friess, H.; Büchler, M. W.; Ceyhan, G. O.; Reber, H. A.; Strieter, R. M.; Hines, O. J. Blockade of the chemokine receptor CXCR2 inhibits pancreatic cancer cell-induced angiogenesis Cancer Lett. 2006, 241 (2) 221-7
19. Hansel, D. E.; Rahman, A.; House, M.; Ashfaq, R.; Berg, K.; Yeo, C. J.; Maitra, A. Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms Clin. Cancer Res. 2004, 10 (18) 6152-8
20. Alvero, A. B.; Chen, R.; Fu, H. H.; Montagna, M.; Schwartz, P. E.; Rutherford, T.; Silasi, D. A.; Steffensen, K. D.; Waldstrom, M.; Visintin, I.; Mor, G. Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance Cell Cycle 2009, 8 (1) 158-66
21. Birnie, R.; Bryce, S. D.; Roome, C.; Dussupt, V.; Droop, A.; Lang, S. H.; Berry, P. A.; Hyde, C. F.; Lewis, J. L.; Stower, M. J.; Maitland, N. J.; Collins, A. T. Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions Genome Biol. 2008, 9 (5) R83
22. Newmeyer DD, Ferguson-Miller, S. Mitochondria: releasing power for life and unleashing the machineries of death Cell 2003, 112 (4) 481-90
23. Lu, J.; Sharma, L. K.; Bai, Y. Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis Cell Res. 2009, 19 (7) 802-15
24. Bapat, S. A. Evolution of cancer stem cells Semin. Cancer Biol. 2007, 17 (3) 204-13
25. Guerra, C.; Schuhmacher, A. J.; Cañamero, M.; Grippo, P. J.; Verdaguer, L.; Pérez-Gallego, L.; Dubus, P.; Sandgren, E. P.; Barbacid, M. Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice Cancer Cell 2007, 11 (3) 291-302