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Volumn 71, Issue 5, 2011, Pages 1584-1596

Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; APC PROTEIN; BONE MORPHOGENETIC PROTEIN; ESTROGEN RECEPTOR ALPHA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROGESTERONE RECEPTOR; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 79952240856     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-3166     Document Type: Article
Times cited : (56)

References (56)
  • 2
    • 0036993579 scopus 로고    scopus 로고
    • Role of stroma in carcinogenesis of the prostate
    • DOI 10.1046/j.1432-0436.2002.700902.x
    • Cunha GR, Hayward SW, Wang YZ. Role of stroma in carcinogenesis of the prostate. Differentiation 2002;70:473-85. (Pubitemid 36194313)
    • (2002) Differentiation , vol.70 , Issue.9-10 , pp. 473-485
    • Cunha, G.R.1    Hayward, S.W.2    Wang, Y.Z.3
  • 3
    • 0035577664 scopus 로고    scopus 로고
    • Epithelial-stromal tissue interaction in paramesonephric (Mullerian) epithelial differentiation
    • DOI 10.1006/dbio.2001.0458
    • Kurita T, Cooke PS, Cunha GR. Epithelial-stromal tissue interaction in paramesonephric (Mullerian) epithelial differentiation. Dev Biol 2001;240:194-211. (Pubitemid 33143820)
    • (2001) Developmental Biology , vol.240 , Issue.1 , pp. 194-211
    • Kurita, T.1    Cooke, P.S.2    Cunha, G.R.3
  • 6
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • DOI 10.1038/nature03096
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-7. (Pubitemid 39551661)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 7
    • 0036843937 scopus 로고    scopus 로고
    • Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
    • DOI 10.1038/ng1013
    • Kurose K, Gilley K, Matsumoto S, Watson PH, Zhou XP, Eng C. Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas. Nat Genet 2002;32:355-7. (Pubitemid 35266108)
    • (2002) Nature Genetics , vol.32 , Issue.3 , pp. 355-357
    • Kurose, K.1    Gilley, K.2    Matsumoto, S.3    Watson, P.H.4    Zhou, X.-P.5    Eng, C.6
  • 9
    • 8644251375 scopus 로고    scopus 로고
    • Down's syndrome protects against breast cancer: Is a constitutional cell microenvironment the key?
    • Benard J, Beron-Gaillard N, Satge D. Down's syndrome protects against breast cancer: is a constitutional cell microenvironment the key? Int J Cancer 2005;113:168-70.
    • (2005) Int J Cancer , vol.113 , pp. 168-170
    • Benard, J.1    Beron-Gaillard, N.2    Satge, D.3
  • 12
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene
    • DOI 10.1242/jcs.03485
    • Aoki K, Taketo MM. Adenomatous polyposis coli (APC): a multifunctional tumor suppressor gene. J Cell Sci 2007;120:3327-35. (Pubitemid 350028340)
    • (2007) Journal of Cell Science , vol.120 , Issue.19 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 15
    • 0036144615 scopus 로고    scopus 로고
    • Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells
    • Arnold JT, Lessey BA, Seppala M, Kaufman DG. Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells. Cancer Res 2002;62:79-88. (Pubitemid 34073990)
    • (2002) Cancer Research , vol.62 , Issue.1 , pp. 79-88
    • Arnold, J.T.1    Lessey, B.A.2    Seppala, M.3    Kaufman, D.G.4
  • 16
    • 13844266441 scopus 로고    scopus 로고
    • Age dependent association of endometrial polyps with increased risk of cancer involvement
    • Hileeto D, Fadare O, Martel M, Zheng W. Age dependent association of endometrial polyps with increased risk of cancer involvement. World J Surg Oncol 2005;3:8.
    • (2005) World J Surg Oncol , vol.3 , pp. 8
    • Hileeto, D.1    Fadare, O.2    Martel, M.3    Zheng, W.4
  • 18
    • 0028906443 scopus 로고
    • Endometrial polyps with predominant stromal component are characterized by a t(6;14)(p21;q24) translocation
    • Vanni R, Marras S, Andria M, Faa G. Endometrial polyps with predominant stromal component are characterized by a t(6;14)(p21;q24) translocation. Cancer Res 1995;55:31-3.
    • (1995) Cancer Res , vol.55 , pp. 31-33
    • Vanni, R.1    Marras, S.2    Andria, M.3    Faa, G.4
  • 19
    • 0036842115 scopus 로고    scopus 로고
    • Requirement of Bmpr1a for Mullerian duct regression during male sexual development
    • DOI 10.1038/ng1003
    • Jamin SP, Arango NA, Mishina Y, Hanks MC, Behringer RR. Requirement of Bmpr1a for Mullerian duct regression during male sexual development. Nat Genet 2002;32:408-10. (Pubitemid 35266116)
    • (2002) Nature Genetics , vol.32 , Issue.3 , pp. 408-410
    • Jamin, S.P.1    Arango, N.A.2    Mishina, Y.3    Hanks, M.C.4    Behringer, R.R.5
  • 21
    • 77950355151 scopus 로고    scopus 로고
    • Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis
    • Tanwar PS, Kaneko-Tarui T, Zhang L, Rani P, Taketo MM, Teixeira J. Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis. Biol Reprod 2010;82:422-32.
    • (2010) Biol Reprod , vol.82 , pp. 422-432
    • Tanwar, P.S.1    Kaneko-Tarui, T.2    Zhang, L.3    Rani, P.4    Taketo, M.M.5    Teixeira, J.6
  • 22
    • 69849087905 scopus 로고    scopus 로고
    • Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice
    • Tanwar PS, Lee HJ, Zhang L, Zukerberg LR, Taketo MM, Rueda BR, et al. Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice. Biol Reprod 2009;81:545-52.
    • (2009) Biol Reprod , vol.81 , pp. 545-552
    • Tanwar, P.S.1    Lee, H.J.2    Zhang, L.3    Zukerberg, L.R.4    Taketo, M.M.5    Rueda, B.R.6
  • 23
    • 28244487293 scopus 로고    scopus 로고
    • Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium
    • DOI 10.1016/j.ydbio.2005.09.045, PII S0012160605006822
    • Arango NA, Szotek PP, Manganaro TF, Oliva E, Donahoe PK, Teixeira J. Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium. Dev Biol 2005;288:276-83. (Pubitemid 41713169)
    • (2005) Developmental Biology , vol.288 , Issue.1 , pp. 276-283
    • Arango, N.A.1    Szotek, P.P.2    Manganaro, T.F.3    Oliva, E.4    Donahoe, P.K.5    Teixeira, J.6
  • 25
    • 67650561888 scopus 로고    scopus 로고
    • Cells with characteristics of cancer stem/progenitor cells express the CD133 antigen in human endometrial tumors
    • Rutella S, Bonanno G, Procoli A, Mariotti A, Corallo M, Prisco MG, et al. Cells with characteristics of cancer stem/progenitor cells express the CD133 antigen in human endometrial tumors. Clin Cancer Res 2009;15:4299-311.
    • (2009) Clin Cancer Res , vol.15 , pp. 4299-4311
    • Rutella, S.1    Bonanno, G.2    Procoli, A.3    Mariotti, A.4    Corallo, M.5    Prisco, M.G.6
  • 28
    • 37849043339 scopus 로고    scopus 로고
    • Mechanism and functional consequences of loss of FOXO1 expression in endometrioid endometrial cancer cells
    • Goto T, Takano M, Albergaria A, Briese J, Pomeranz KM, Cloke B, et al. Mechanism and functional consequences of loss of FOXO1 expression in endometrioid endometrial cancer cells. Oncogene 2008;27:9-19.
    • (2008) Oncogene , vol.27 , pp. 9-19
    • Goto, T.1    Takano, M.2    Albergaria, A.3    Briese, J.4    Pomeranz, K.M.5    Cloke, B.6
  • 29
    • 41549119005 scopus 로고    scopus 로고
    • Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments
    • Klapholz-Brown Z, Walmsley GG, Nusse YM, Nusse R, Brown PO. Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. PLoS One 2007;2:e945.
    • (2007) PLoS One , vol.2
    • Klapholz-Brown, Z.1    Walmsley, G.G.2    Nusse, Y.M.3    Nusse, R.4    Brown, P.O.5
  • 30
    • 0032489508 scopus 로고    scopus 로고
    • Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
    • DOI 10.1016/S0092-8674(00)81132-0
    • Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998;92:645-56. (Pubitemid 28141513)
    • (1998) Cell , vol.92 , Issue.5 , pp. 645-656
    • Takaku, K.1    Oshima, M.2    Miyoshi, H.3    Matsui, M.4    Seldin, M.F.5    Taketo, M.M.6
  • 31
    • 39149088615 scopus 로고    scopus 로고
    • Stromal inactivation of BMPRII leads to colorectal epithelial overgrowth and polyp formation
    • DOI 10.1038/sj.onc.1210720, PII 1210720
    • Beppu H, Mwizerwa ON, Beppu Y, Dattwyler MP, Lauwers GY, Bloch KD, et al. Stromal inactivation of BMPRII leads to colorectal epithelial overgrowth and polyp formation. Oncogene 2008;27:1063-70. (Pubitemid 351253183)
    • (2008) Oncogene , vol.27 , Issue.8 , pp. 1063-1070
    • Beppu, H.1    Mwizerwa, O.N.2    Beppu, Y.3    Dattwyler, M.P.4    Lauwers, G.Y.5    Bloch, K.D.6    Goldstein, A.M.7
  • 32
    • 76349096670 scopus 로고    scopus 로고
    • Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner
    • Erez N, Truitt M, Olson P, Arron ST, Hanahan D. Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner. Cancer Cell 2010;17:135-47.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3    Arron, S.T.4    Hanahan, D.5
  • 35
    • 37549006796 scopus 로고    scopus 로고
    • Clinical and biological significance of vascular endothelial growth factor in endometrial cancer
    • Kamat AA, Merritt WM, Coffey D, Lin YG, Patel PR, Broaddus R, et al. Clinical and biological significance of vascular endothelial growth factor in endometrial cancer. Clin Cancer Res 2007;13:7487-95.
    • (2007) Clin Cancer Res , vol.13 , pp. 7487-7495
    • Kamat, A.A.1    Merritt, W.M.2    Coffey, D.3    Lin, Y.G.4    Patel, P.R.5    Broaddus, R.6
  • 36
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005;121:335-48. (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 39
    • 2942621854 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha-induced cell proliferation and its possible regulation by CD26/dipeptidyl peptidase IV in endometrial adenocarcinoma
    • DOI 10.1002/ijc.20183
    • Mizokami Y, Kajiyama H, Shibata K, Ino K, Kikkawa F, Mizutani S. Stromal cell-derived factor-1alpha-induced cell proliferation and its possible regulation by CD26/dipeptidyl peptidase IV in endometrial adenocarcinoma. Int J Cancer 2004;110:652-9. (Pubitemid 38746022)
    • (2004) International Journal of Cancer , vol.110 , Issue.5 , pp. 652-659
    • Mizokami, Y.1    Kajiyama, H.2    Shibata, K.3    Ino, K.4    Kikkawa, F.5    Mizutani, S.6
  • 41
    • 0035011886 scopus 로고    scopus 로고
    • Hamartomatous polyposis syndromes: Molecular genetics, neoplastic risk, and surveillance recommendations
    • DOI 10.1245/aso.2001.8.4.319
    • Wirtzfeld DA, Petrelli NJ, Rodriguez-Bigas MA. Hamartomatous polyposis syndromes: molecular genetics, neoplastic risk, and surveillance recommendations. Ann Surg Oncol 2001;8:319-27. (Pubitemid 32422857)
    • (2001) Annals of Surgical Oncology , vol.8 , Issue.4 , pp. 319-327
    • Wirtzfeld, D.A.1    Petrelli, N.J.2    Rodriguez-Bigas, M.A.3
  • 43
    • 51349113366 scopus 로고    scopus 로고
    • Importance of Wnt signaling in the tumor stroma microenvironment
    • Macheda ML, Stacker SA. Importance of Wnt signaling in the tumor stroma microenvironment. Curr Cancer Drug Targets 2008;8:454-65.
    • (2008) Curr Cancer Drug Targets , vol.8 , pp. 454-465
    • Macheda, M.L.1    Stacker, S.A.2
  • 44
    • 0031690260 scopus 로고    scopus 로고
    • Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract
    • Miller C, Sassoon DA. Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Development 1998;125:3201-11. (Pubitemid 28434418)
    • (1998) Development , vol.125 , Issue.16 , pp. 3201-3211
    • Miller, C.1    Sassoon, D.A.2
  • 45
    • 2542557308 scopus 로고    scopus 로고
    • Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus
    • DOI 10.1242/dev.01090
    • Mericskay M, Kitajewski J, Sassoon D. Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus. Development 2004;131:2061-72. (Pubitemid 38702039)
    • (2004) Development , vol.131 , Issue.9 , pp. 2061-2072
    • Mericskay, M.1    Kitajewski, J.2    Sassoon, D.3
  • 46
    • 58149343796 scopus 로고    scopus 로고
    • Beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus
    • Jeong JW, Lee HS, Franco HL, Broaddus RR, Taketo MM, Tsai SY, et al. Beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus. Oncogene 2009;28:31-40.
    • (2009) Oncogene , vol.28 , pp. 31-40
    • Jeong, J.W.1    Lee, H.S.2    Franco, H.L.3    Broaddus, R.R.4    Taketo, M.M.5    Tsai, S.Y.6
  • 47
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: What have we learned and where will they lead us?
    • Couse JF, Korach KS. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 1999;20:358-417.
    • (1999) Endocr Rev , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 50
    • 0022536523 scopus 로고
    • Prediction of clinical outcome with estrogen and progestin receptor concentrations and their relationships to clinical and histopathological variables in endometrial cancer
    • Kauppila AJ, Isotalo HE, Kivinen ST, Vihko RK. Prediction of clinical outcome with estrogen and progestin receptor concentrations and their relationships to clinical and histopathological variables in endometrial cancer. Cancer Res 1986;46:5380-4. (Pubitemid 16008319)
    • (1986) Cancer Research , vol.46 , Issue.10 , pp. 5380-5384
    • Kauppila, A.J.I.1    Isotalo, H.E.2    Kivinen, S.T.3    Vihko, R.K.4
  • 51
    • 70449434786 scopus 로고    scopus 로고
    • Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha
    • Collins F, MacPherson S, Brown P, Bombail V, Williams AR, Anderson RA, et al. Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha. BMC Cancer 2009;9:330.
    • (2009) BMC Cancer , vol.9 , pp. 330
    • Collins, F.1    MacPherson, S.2    Brown, P.3    Bombail, V.4    Williams, A.R.5    Anderson, R.A.6
  • 52
    • 4944246588 scopus 로고    scopus 로고
    • Loss of ERbeta expression as a common step in estrogen-dependent tumor progression
    • DOI 10.1677/erc.1.00800
    • Bardin A, Boulle N, Lazennec G, Vignon F, Pujol P. Loss of ERbeta expression as a common step in estrogen-dependent tumor progression. Endocr Relat Cancer 2004;11:537-51. (Pubitemid 39331282)
    • (2004) Endocrine-Related Cancer , vol.11 , Issue.3 , pp. 537-551
    • Bardin, A.1    Boulle, N.2    Lazennec, G.3    Vignon, F.4    Pujol, P.5
  • 55
    • 79952231107 scopus 로고    scopus 로고
    • Estrogen induces stromal cell-derived factor 1 (SDF-1/CXCL12) production in human endometrial stromal cells: A possible role of endometrial epithelial cell growth
    • Tsutsumi A, Okada H, Nakamoto T, Okamoto R, Yasuda K, Kanzaki H. Estrogen induces stromal cell-derived factor 1 (SDF-1/CXCL12) production in human endometrial stromal cells: a possible role of endometrial epithelial cell growth. Fertil Steril 2010.
    • (2010) Fertil Steril
    • Tsutsumi, A.1    Okada, H.2    Nakamoto, T.3    Okamoto, R.4    Yasuda, K.5    Kanzaki, H.6


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