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Volumn 27, Issue 8, 2008, Pages 1063-1070

Stromal inactivation of BMPRII leads to colorectal epithelial overgrowth and polyp formation

Author keywords

BMPRII; Bone morphogenetic proteins; Colorectal polyps; Nestin hamartomatous polyps; Stromal epithelial interactions

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2; NESTIN;

EID: 39149088615     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210720     Document Type: Article
Times cited : (64)

References (26)
  • 1
    • 0036311203 scopus 로고    scopus 로고
    • Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps
    • Adegboyega PA, Mifflin RC, DiMari JF, Saada JI, Powell DW. (2002). Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps. Arch Pathol Lab Med 126: 829-836.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 829-836
    • Adegboyega, P.A.1    Mifflin, R.C.2    DiMari, J.F.3    Saada, J.I.4    Powell, D.W.5
  • 2
    • 33646894742 scopus 로고    scopus 로고
    • Bmp signaling is required for intestinal growth and morphogenesis
    • Batts LE, Polk DB, Dubois RN, Kulessa H. (2006). Bmp signaling is required for intestinal growth and morphogenesis. Dev Dyn 235: 1563-1570.
    • (2006) Dev Dyn , vol.235 , pp. 1563-1570
    • Batts, L.E.1    Polk, D.B.2    Dubois, R.N.3    Kulessa, H.4
  • 3
    • 17044369273 scopus 로고    scopus 로고
    • Generation of a floxed allele of the mouse BMP type II receptor gene
    • Beppu H, Lei H, Bloch KD, Li E. (2005). Generation of a floxed allele of the mouse BMP type II receptor gene. Genesis 41: 133-137.
    • (2005) Genesis , vol.41 , pp. 133-137
    • Beppu, H.1    Lei, H.2    Bloch, K.D.3    Li, E.4
  • 4
    • 0842288323 scopus 로고    scopus 로고
    • TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, Shappell S et al. (2004a). TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303: 848-851.
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1    Chytil, A.2    Plieth, D.3    Gorska, A.E.4    Dumont, N.5    Shappell, S.6
  • 5
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL. (2004b). Stromal fibroblasts in cancer initiation and progression. Nature 432: 332-337.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 6
    • 24344493473 scopus 로고    scopus 로고
    • Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation
    • Chen AL, Soman KV, Rychahou PG, Luxon BA, Evers BM. (2005). Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation. Surgery 138: 382-390.
    • (2005) Surgery , vol.138 , pp. 382-390
    • Chen, A.L.1    Soman, K.V.2    Rychahou, P.G.3    Luxon, B.A.4    Evers, B.M.5
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 1542618115 scopus 로고    scopus 로고
    • Haramis AP, Begthel H, van den BornM, van Es J, Jonkheer S, Offerhaus GJ et al. (2004). De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine. Science 303: 1684-1686.
    • Haramis AP, Begthel H, van den BornM, van Es J, Jonkheer S, Offerhaus GJ et al. (2004). De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine. Science 303: 1684-1686.
  • 10
    • 33846600427 scopus 로고    scopus 로고
    • PTEN-deficient intestinal stem cells initiate intestinal polyposis
    • He XC, Yin T, Grindley JC, Tian Q, Sato T, Tao WA et al. (2007). PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet 39: 189-198.
    • (2007) Nat Genet , vol.39 , pp. 189-198
    • He, X.C.1    Yin, T.2    Grindley, J.C.3    Tian, Q.4    Sato, T.5    Tao, W.A.6
  • 11
    • 6944224156 scopus 로고    scopus 로고
    • BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
    • He XC, Zhang J, Tong WG, Tawfik O, Ross J, Scoville DH et al. (2004). BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 36: 1117-1121.
    • (2004) Nat Genet , vol.36 , pp. 1117-1121
    • He, X.C.1    Zhang, J.2    Tong, W.G.3    Tawfik, O.4    Ross, J.5    Scoville, D.H.6
  • 14
    • 3142746721 scopus 로고    scopus 로고
    • The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations
    • Howe JR, Sayed MG, Ahmed AF, Ringold J, Larsen-Haidle J, Merg A et al. (2004). The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations. J Med Genet 41: 484-491.
    • (2004) J Med Genet , vol.41 , pp. 484-491
    • Howe, J.R.1    Sayed, M.G.2    Ahmed, A.F.3    Ringold, J.4    Larsen-Haidle, J.5    Merg, A.6
  • 15
    • 0030987867 scopus 로고    scopus 로고
    • A juvenile polyposis tumor suppressor locus at 10q22 is deleted from nonepithelial cells in the lamina propria
    • Jacoby RF, Schlack S, Cole CE, Skarbek M, Harris C, Meisner LF. (1997). A juvenile polyposis tumor suppressor locus at 10q22 is deleted from nonepithelial cells in the lamina propria. Gastroenterology 112: 1398-1403.
    • (1997) Gastroenterology , vol.112 , pp. 1398-1403
    • Jacoby, R.F.1    Schlack, S.2    Cole, C.E.3    Skarbek, M.4    Harris, C.5    Meisner, L.F.6
  • 16
    • 33745578957 scopus 로고    scopus 로고
    • Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
    • Kim BG, Li C, Qiao W, Mamura M, Kasprzak B, Anver M et al. (2006). Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Nature 441: 1015-1019.
    • (2006) Nature , vol.441 , pp. 1015-1019
    • Kim, B.G.1    Li, C.2    Qiao, W.3    Mamura, M.4    Kasprzak, B.5    Anver, M.6
  • 18
    • 34548853386 scopus 로고    scopus 로고
    • Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity
    • in press
    • Liu D, Wang J, Kinzel B, Müeller M, Mao X, Valdez R et al. (2007). Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity. Blood (in press).
    • (2007) Blood
    • Liu, D.1    Wang, J.2    Kinzel, B.3    Müeller, M.4    Mao, X.5    Valdez, R.6
  • 19
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk
    • Miyazono K, Maeda S, Imamura T. (2005). BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev 16: 251-263.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 20
    • 0037829660 scopus 로고    scopus 로고
    • Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
    • Pinto D, Gregorieff A, Begthel H, Clevers H. (2003). Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 17: 1709-1713.
    • (2003) Genes Dev , vol.17 , pp. 1709-1713
    • Pinto, D.1    Gregorieff, A.2    Begthel, H.3    Clevers, H.4
  • 23
    • 0344413420 scopus 로고    scopus 로고
    • Live and let die in the intestinal epithelium
    • Sancho E, Batlle E, Clevers H. (2003). Live and let die in the intestinal epithelium. Curr Opin Cell Biol 15: 763-770.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 763-770
    • Sancho, E.1    Batlle, E.2    Clevers, H.3
  • 24
    • 0033397681 scopus 로고    scopus 로고
    • Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch
    • Trumpp A, Depew MJ, Rubenstein JL, Bishop JM, Martin GR. (1999). Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev 13: 3136-3148.
    • (1999) Genes Dev , vol.13 , pp. 3136-3148
    • Trumpp, A.1    Depew, M.J.2    Rubenstein, J.L.3    Bishop, J.M.4    Martin, G.R.5
  • 25
    • 6944244098 scopus 로고    scopus 로고
    • Linking pathways in colorectal cancer
    • van den Brink GR. (2004). Linking pathways in colorectal cancer. Nat Genet 36: 1038-1039.
    • (2004) Nat Genet , vol.36 , pp. 1038-1039
    • van den Brink, G.R.1
  • 26
    • 0035011886 scopus 로고    scopus 로고
    • Hamartomatous polyposis syndromes: Molecular genetics, neoplastic risk, and surveillance recommendations
    • Wirtzfeld DA, Petrelli NJ, Rodriguez-Bigas MA. (2001). Hamartomatous polyposis syndromes: molecular genetics, neoplastic risk, and surveillance recommendations. Ann Surg Oncol 8: 319-327.
    • (2001) Ann Surg Oncol , vol.8 , pp. 319-327
    • Wirtzfeld, D.A.1    Petrelli, N.J.2    Rodriguez-Bigas, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.