-
1
-
-
33644778691
-
Amyloid-β peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease
-
3381-3338
-
Atamna H., Boyle K. Amyloid-β peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease. Proc Natl Acad Sci USA 2006; 103: 3381-338.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
-
-
Atamna, H.1
Boyle, K.2
-
2
-
-
50849135137
-
Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia
-
Auchere F., Santos R., Planamente S. et al. Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia. Hum Mol Genet 2008; 17: 2790-2802.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2790-2802
-
-
Auchere, F.1
Santos, R.2
Planamente, S.3
-
3
-
-
21544450545
-
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease
-
Bae B.I., Xu H., Igarashi S. et al. p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron 2005; 47: 29-41.
-
(2005)
Neuron
, vol.47
, pp. 29-41
-
-
Bae, B.I.1
Xu, H.2
Igarashi, S.3
-
4
-
-
33748028841
-
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
-
Barsoum M.J., Yuan H., Gerencser A.A. et al. Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J 2006; 25: 3900-3911.
-
(2006)
EMBO J
, vol.25
, pp. 3900-3911
-
-
Barsoum, M.J.1
Yuan, H.2
Gerencser, A.A.3
-
5
-
-
55849091446
-
Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria
-
Bilsland L.G., Nirmalananthan N., Yip J. et al. Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria. J Neurochem 2008; 107: 1271-1283.
-
(2008)
J Neurochem
, vol.107
, pp. 1271-1283
-
-
Bilsland, L.G.1
Nirmalananthan, N.2
Yip, J.3
-
6
-
-
21544459062
-
The role of calcineurin in amyloid-β-peptidesmediated cell death
-
Cardoso S.M., Oliveira C.R. The role of calcineurin in amyloid-β-peptidesmediated cell death. Brain Res 2005; 1050: 1-7.
-
(2005)
Brain Res
, vol.1050
, pp. 1-7
-
-
Cardoso, S.M.1
Oliveira, C.R.2
-
7
-
-
27744600579
-
Over-expression of τ-results in defective synaptic transmission in Drosophila neuromuscular junctions
-
Chee F.C., Mudher A., Cuttle M.F. et al. Over-expression of τ-results in defective synaptic transmission in Drosophila neuromuscular junctions. Neurobiol Dis 2005; 20: 918-928.
-
(2005)
Neurobiol Dis
, vol.20
, pp. 918-928
-
-
Chee, F.C.1
Mudher, A.2
Cuttle, M.F.3
-
8
-
-
34250211094
-
Mitochondrial Aβ: A potential cause of metabolic dysfunction in Alzheimer's disease
-
Chen X., Yan S.D. Mitochondrial Aβ: a potential cause of metabolic dysfunction in Alzheimer's disease. IUBMB Life 2006; 58: 686-694.
-
(2006)
IUBMB Life
, vol.58
, pp. 686-694
-
-
Chen, X.1
Yan, S.D.2
-
9
-
-
30744474942
-
Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL
-
Chou A.H., Yeh T.H., Kuo Y.L. et al. Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL. Neurobiol Dis 2006; 21: 333-345.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 333-345
-
-
Chou, A.H.1
Yeh, T.H.2
Kuo, Y.L.3
-
10
-
-
35548991459
-
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
-
De Vos K.J., Chapman A.L., Tennant M.E. et al. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Hum Mol Genet 2007; 16: 2720-2728.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2720-2728
-
-
de Vos, K.J.1
Chapman, A.L.2
Tennant, M.E.3
-
11
-
-
38049155818
-
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
-
Deniaud A., Sharaf el dein O., Maillier E. et al. Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene 2008; 27: 285-299.
-
(2008)
Oncogene
, vol.27
, pp. 285-299
-
-
Deniaud, A.1
Sharaf El dein, O.2
Maillier, E.3
-
12
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
-
Devi L., Prabhu B.M., Galati D.F. et al. Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. J Neurosci 2006; 26: 9057-9068.
-
(2006)
J Neurosci
, vol.26
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
-
13
-
-
44049099669
-
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi L., Raghavendran V., Prabhu B.M. et al. Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J Biol Chem 2008; 283: 9089-9100.
-
(2008)
J Biol Chem
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
-
14
-
-
0037417220
-
Apoptosis and caspases in neurodegenerative diseases
-
Friedlander R.M. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 2003; 348: 1365-1375.
-
(2003)
N Engl J Med
, vol.348
, pp. 1365-1375
-
-
Friedlander, R.M.1
-
15
-
-
0037240427
-
Programmed cell death in amyotrophic lateral sclerosis
-
Guegan C., Przedborski S. Programmed cell death in amyotrophic lateral sclerosis. J Clin Invest 2003; 111: 153-161.
-
(2003)
J Clin Invest
, vol.111
, pp. 153-161
-
-
Guegan, C.1
Przedborski, S.2
-
16
-
-
53149088265
-
Tunicamycin-induced ER stress upregulates the expression of mitochondrial HtrA2 and promotes apoptosis through the cytosolic release of HtrA2
-
Han C., Nam M.K., Park H.J. et al. Tunicamycin-induced ER stress upregulates the expression of mitochondrial HtrA2 and promotes apoptosis through the cytosolic release of HtrA2. J Microbiol Biotechnol 2008; 18: 1197-1202.
-
(2008)
J Microbiol Biotechnol
, vol.18
, pp. 1197-1202
-
-
Han, C.1
Nam, M.K.2
Park, H.J.3
-
17
-
-
43049159563
-
Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13)
-
Hansen J., Corydon T.J., Palmfeldt J. et al. Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13). Neuroscience 2008; 153: 474-482.
-
(2008)
Neuroscience
, vol.153
, pp. 474-482
-
-
Hansen, J.1
Corydon, T.J.2
Palmfeldt, J.3
-
18
-
-
28244445138
-
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy
-
Hoglinger G.U., Lannuzel A., Khondiker M.E. et al. The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy. J Neurochem 2005; 95: 930-939.
-
(2005)
J Neurochem
, vol.95
, pp. 930-939
-
-
Hoglinger, G.U.1
Lannuzel, A.2
Khondiker, M.E.3
-
19
-
-
36749067790
-
Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis
-
Ilieva E.V., Ayala V., Jove M. et al. Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis. Brain 2007; 130: 3111-3123.
-
(2007)
Brain
, vol.130
, pp. 3111-3123
-
-
Ilieva, E.V.1
Ayala, V.2
Jove, M.3
-
20
-
-
57449098698
-
In situ Abeta pores in AD brain are cylindrical assembly of Abeta protofilaments
-
Inoue S. In situ Abeta pores in AD brain are cylindrical assembly of Abeta protofilaments. Amyloid 2008; 15: 223-233.
-
(2008)
Amyloid
, vol.15
, pp. 223-233
-
-
Inoue, S.1
-
21
-
-
33748909721
-
Phospholipase D1 is up-regulated in the mitochondrial fraction from the brains of Alzheimer's disease patients
-
Jin J.K., Kim N.H., Lee Y.J. et al. Phospholipase D1 is up-regulated in the mitochondrial fraction from the brains of Alzheimer's disease patients. Neurosci Lett 2006; 407: 263-267.
-
(2006)
Neurosci Lett
, vol.407
, pp. 263-267
-
-
Jin, J.K.1
Kim, N.H.2
Lee, Y.J.3
-
22
-
-
63049138430
-
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
-
Junn E., Jang W.H., Zhao X. et al. Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. J Neurosci Res 2009; 87: 123-129.
-
(2009)
J Neurosci Res
, vol.87
, pp. 123-129
-
-
Junn, E.1
Jang, W.H.2
Zhao, X.3
-
23
-
-
46349098565
-
Partial inhibition of complex I activity increases Ca-independent glutamate release rates from depolarized synaptosomes
-
Kilbride S.M., Telford J.E., Tipton K.F., Davey G.P. Partial inhibition of complex I activity increases Ca-independent glutamate release rates from depolarized synaptosomes. J Neurochem 2008; 106: 826-834.
-
(2008)
J Neurochem
, vol.106
, pp. 826-834
-
-
Kilbride, S.M.1
Telford, J.E.2
Tipton, K.F.3
Davey, G.P.4
-
24
-
-
24144467440
-
Differential effect of calmodulin antagonists on MG132-induced mitochondrial dysfunction and cell death in PC12 cells
-
Lee C.S., Han E.S., Han Y.S., Bang H. Differential effect of calmodulin antagonists on MG132-induced mitochondrial dysfunction and cell death in PC12 cells. Brain Res Bull 2005; 67: 225-234.
-
(2005)
Brain Res Bull
, vol.67
, pp. 225-234
-
-
Lee, C.S.1
Han, E.S.2
Han, Y.S.3
Bang, H.4
-
25
-
-
0037016741
-
Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form
-
Lee H.-J. Choi C., Lee S.-J. Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form. J Biol Chem 2002; 277: 671-678.
-
(2002)
J Biol Chem
, vol.277
, pp. 671-678
-
-
Lee, H.-J.1
Choi, C.2
Lee, S.-J.3
-
26
-
-
15944413899
-
The paradigm of Huntington's disease: Therapeutic opportunites in neurodegeneration
-
Leegwater-Kim J., Cha J.-H. J. The paradigm of Huntington's disease: therapeutic opportunites in neurodegeneration. NeuroRx 2004; 1: 128-138.
-
(2004)
NeuroRx
, vol.1
, pp. 128-138
-
-
Leegwater-Kim, J.1
Cha, J.-H.J.2
-
27
-
-
45549091524
-
The stress rheostat: An interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration
-
Matus S., Lisbona F., Torres M. et al. The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration. Curr Mol Med 2008; 8: 157-172.
-
(2008)
Curr Mol Med
, vol.8
, pp. 157-172
-
-
Matus, S.1
Lisbona, F.2
Torres, M.3
-
28
-
-
24644443839
-
Oxidative stress: The old enemy in Alzheimer's disease pathophysiology
-
Moreira P.I., Honda K., Liu Q. et al. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res 2005; 2: 403-408.
-
(2005)
Curr Alzheimer Res
, vol.2
, pp. 403-408
-
-
Moreira, P.I.1
Honda, K.2
Liu, Q.3
-
29
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D., Tanaka A., Suen D.F., Youle R.J. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008; 183: 795-803.
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
30
-
-
42449095464
-
Mitochondrial association of α-synuclein causes oxidative stress
-
Parihar M.S., Parihar A., Fujita M. et al. Mitochondrial association of α-synuclein causes oxidative stress. Cell Mol Life Sci 2008; 65: 1272-1284.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1272-1284
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
-
31
-
-
57749194390
-
The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process
-
Park J., Lee G., Chung J. The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. Biochem Biophys Res Commun 2009; 378: 518-523.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 518-523
-
-
Park, J.1
Lee, G.2
Chung, J.3
-
32
-
-
85047683832
-
1-antitrypsyn deficiency: An aggregated protein induces mitochondrial injury
-
1-antitrypsyn deficiency: an aggregated protein induces mitochondrial injury. J Clin Invest 2002; 110: 1579-1583.
-
(2002)
J Clin Invest
, vol.110
, pp. 1579-1583
-
-
Perlmutter, D.H.1
-
33
-
-
33847317865
-
Cellular and subcellular localization of Huntingtin aggregates in the brain of a rat transgenic for Huntington disease
-
Petrasch-Parwez E., Nguyen H.P., Lobbecke-Schumacher M. et al. Cellular and subcellular localization of Huntingtin aggregates in the brain of a rat transgenic for Huntington disease. J Comp Neurol 2007; 501: 716-730.
-
(2007)
J Comp Neurol
, vol.501
, pp. 716-730
-
-
Petrasch-Parwez, E.1
Nguyen, H.P.2
Lobbecke-Schumacher, M.3
-
34
-
-
57649194934
-
What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?
-
Plun-Favreau H., Gandhi S., Wood-Kaczmar A. et al. What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease? Ann N Y Acad Sci 2008; 1147: 30-36.
-
(2008)
Ann N Y Acad Sci
, vol.1147
, pp. 30-36
-
-
Plun-Favreau, H.1
Gandhi, S.2
Wood-Kaczmar, A.3
-
35
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole A.C., Thomas R.E., Andrews L.A. et al. The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci USA 2008; 105: 1638-1643.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
-
36
-
-
39149122810
-
Amyloid β, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
-
Reddy P.H., Beal M.F. Amyloid β, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med 2008; 14: 45-53.
-
(2008)
Trends Mol Med
, vol.14
, pp. 45-53
-
-
Reddy, P.H.1
Beal, M.F.2
-
37
-
-
51949099008
-
Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells
-
Schmidt C., Lepsverdize E., Chi S.L. et al. Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells. Mol Psychiat 2008; 13: 953-969.
-
(2008)
Mol Psychiat
, vol.13
, pp. 953-969
-
-
Schmidt, C.1
Lepsverdize, E.2
Chi, S.L.3
-
38
-
-
33846980461
-
Microglia derived from aging mice exhibit an altered inflammatory profile
-
Sierra A., Gottfried-Blackmore A.C., McEwen B.S., Bulloch K. Microglia derived from aging mice exhibit an altered inflammatory profile. Glia 2007; 55: 412-424.
-
(2007)
Glia
, vol.55
, pp. 412-424
-
-
Sierra, A.1
Gottfried-Blackmore, A.C.2
McEwen, B.S.3
Bulloch, K.4
-
39
-
-
29644434199
-
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant α-synucleininduced toxicity
-
Smith W.W., Jiang H., Pei Z. et al. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant α-synucleininduced toxicity. Hum Mol Genet 2005; 14: 3801-3811.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3801-3811
-
-
Smith, W.W.1
Jiang, H.2
Pei, Z.3
-
40
-
-
20444386209
-
Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins
-
Stoica B.A., Movsesyan V.A., Knoblach S.M., Faden A.I. Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. Mol Cell Neurosci 2005; 29: 355-371.
-
(2005)
Mol Cell Neurosci
, vol.29
, pp. 355-371
-
-
Stoica, B.A.1
Movsesyan, V.A.2
Knoblach, S.M.3
Faden, A.I.4
-
41
-
-
2442645048
-
Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover
-
Sullivan P.G., Dragicevic N.B., Deng J.H. et al. Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover. J Biol Chem 2004; 279: 20699-20707.
-
(2004)
J Biol Chem
, vol.279
, pp. 20699-20707
-
-
Sullivan, P.G.1
Dragicevic, N.B.2
Deng, J.H.3
-
42
-
-
33947307791
-
Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1
-
Thies E., Mandelkow E.M. Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1. J Neurosci 2007; 27: 2896-2907.
-
(2007)
J Neurosci
, vol.27
, pp. 2896-2907
-
-
Thies, E.1
Mandelkow, E.M.2
-
43
-
-
4444316194
-
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro
-
nd et al. Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol 2004; 24: 8195-8209.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8195-8209
-
-
Trushina, E.1
Dyer, R.B.2
Badger II, J.D.3
-
44
-
-
58049218922
-
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
Wang X., Su B., Siedlak S.L., Moreira P.I. et al. Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci USA 2008; 105: 19318-19323.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
-
45
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
Xu C., Bailly-Maitre B., Reed J.C. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 2005; 115: 2656-2664.
-
(2005)
J Clin Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
46
-
-
27544479978
-
Aβ25-35 alters Akt activity, resulting in Bad translocation and mitochondrial dysfunction in cerebrovascular endothelial cells
-
Yin K.J., Lee J.M., Chen H. et al. Aβ25-35 alters Akt activity, resulting in Bad translocation and mitochondrial dysfunction in cerebrovascular endothelial cells. J. Cereb. Blood Flow Metab 2005; 25: 1445-1455.
-
(2005)
J. Cereb. Blood Flow Metab
, vol.25
, pp. 1445-1455
-
-
Yin, K.J.1
Lee, J.M.2
Chen, H.3
-
47
-
-
31344437880
-
Okadaic acid induces JNK activation, bim overexpression and mitochondrial dysfunction in cultured rat cortical neurons
-
Yoon S., Choi J., Yoon J. et al. Okadaic acid induces JNK activation, bim overexpression and mitochondrial dysfunction in cultured rat cortical neurons. Neurosci Lett 2006; 394: 190-195.
-
(2006)
Neurosci Lett
, vol.394
, pp. 190-195
-
-
Yoon, S.1
Choi, J.2
Yoon, J.3
-
48
-
-
20344386015
-
Calpains and disease
-
Zatz M., Starling A. Calpains and disease. N Engl J Med 2005; 352: 2413-2423.
-
(2005)
N Engl J Med
, vol.352
, pp. 2413-2423
-
-
Zatz, M.1
Starling, A.2
-
49
-
-
17644411438
-
Energy status, ubiquitin proteasomal function, and oxidative stress during chronic and acute complex I inhibition with rotenone in mesencephalic cultures
-
Zeevalk G.D., Bernard L.P. Energy status, ubiquitin proteasomal function, and oxidative stress during chronic and acute complex I inhibition with rotenone in mesencephalic cultures. Antioxid Redox Signal 2005; 7: 662-672.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 662-672
-
-
Zeevalk, G.D.1
Bernard, L.P.2
|