Amyloid-β peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 9, 2006, Pages 3381-3386

  Atamna, Hani ^a   Boyle, Kathleen ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

Curcumin; Heme deficiency; Mitochondria; Regulatory heme; Serotonin

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; CURCUMIN; DOPA; HEME; HYDROGEN PEROXIDE; PEROXIDASE; PEROXIDASE INHIBITOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CATALYSIS; CELL FREE SYSTEM; CONTROLLED STUDY; CYTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IRON TRANSPORT; MACROMOLECULE; MITOCHONDRIAL DNA DISORDER; NERVE DEGENERATION; NEUROBLASTOMA; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; OXIDATION; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CELL LINE, TUMOR; HEME; HUMANS; IRON; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PEROXIDASES; PROTEIN BINDING; SPECTRUM ANALYSIS;

EID: 33644778691     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0600134103     Document Type: Article

References (49)

1. Billings, L. M., Oddo, S., Green, K. N., McGaugh, J. L. & Laferla, F. M. (2005) Neuron 45, 675-688.
2. Skovronsky, D. M., Doms, R. W. & Lee, V. M. (1998) J. Cell Biol. 141, 1031-1039.
3. Walsh, D. M. & Selkoe, D. J. (2004) Protein Pept. Lett. 11, 213-228.
4. Smith, M. A., Nunomura, A., Zhu, X., Takeda, A. & Perry, G. (2000) Antioxid. Redox. Signal 2, 413-420.
5. Parker, W. D., Jr., Parks, J., Filley, C. M. & Kleinschmidt- DeMasters, B. K. (1994) Neurology 44, 1090-1096.
6. Mutisya, E. M., Bowling, A. C. & Beal, M. F. (1994) J. Neurochem. 63, 2179-2184.
7. Connor, J. R., Snyder, B. S., Beard, J. L., Fine, R. E. & Mufson, E. J. (1992) J. Neurosci. Res. 31, 327-335.
8. Gsell, W., Jungkunz, G. & Riederer, P. (2004) Curr. Pharm. Des. 10, 265-293.
9. Atamna, H. & Frey, W. H., II (2004) Proc. Natl. Acad. Sci. USA 101, 11153-11158.
10. Atamna, H., Killilea, D. W., Killilea, A. N. & Ames, B. N. (2002) Proc. Natl. Acad. Sci. USA 99, 14807-14812.
11. Atamna, H., Liu, J. & Ames, B. N. (2001) J. Biol. Chem. 276, 48410-48416.
12. Atamna, H. (2006) J. Alzheimer's Dis., in press.
13. Atamna, H. (2004) Aging Res. Rev. 3, 303-318.
14. Sellers, V. M., Wu, C. K., Dailey, T. A. & Dailey, H. A. (2001) Biochemistry 40, 9821-9827.
15. Ponka, P., Borova, J. & Neuwirt, J. (1973) Biochim. Biophys. Acta 304, 715-718.
16. Goodfellow, B. J., Dias, J. S., Ferreira, G. C., Henklein, P., Wray, V. & Macedo, A. L. (2001) FEBS Lett. 505, 325-331.
17. Goessling, L. S., Mascotti, D. P. & Thach, R. E. (1998) J. Biol. Chem. 273, 12555-12557.
18. Dioum, E. M., Rutter, J., Tuckerman, J. R., Gonzalez, G., Gilles-Gonzalez, M. A. & McKnight, S. L. (2002) Science 298, 2385-2387.
19. Dhakshinamoorthy, S., Jain, A. K., Bloom, D. A. & Jaiswal, A. K. (2005) J. Biol. Chem. 280, 16891-16900.
20. Brown, K. R., Allan, B. M., Do, P. & Hegg, E. L. (2002) Biochemistry 41, 10906-10913.
21. Wielburski, A. & Nelson, B. D. (1983) Biochem. J. 212, 829-834.
22. Burdick, D., Soreghan, B., Kwon, M., Kosmoski, J., Knauer, M., Henschen, A., Yates, J., Cotman, C. & Glabe, C. (1992) J. Biol. Chem. 267, 546-554.
23. Fawcett, J. R., Bordayo, E. Z., Jackson, K., Liu, H., Peterson, J., Svitak, A. & Frey, W. H., II (2002) Brain Res. 950, 10-20.
24. Howlett, D., Cutler, P., Heales, S. & Camilleri, P. (1997) FEBS Lett. 417, 249-251.
25. Paoli, M., Marles-Wright, J. & Smith, A. (2002) DNA Cell. Biol. 21, 271-280.
26. Ogawa, K., Sun, J., Taketani, S., Nakajima, O., Nishitani, C., Sassa, S., Hayashi, N., Yamamoto, M., Shibahara, S., Fujita, H. & Igarashi, K. (2001) EMBO J. 20, 2835-2843.
27. Bush, A. I. (2003) Trends Neurosci. 26, 207-214.
28. Fukuyama, K., Kunishima, N., Amada, F., Kubota, T. & Matsubara, H. (1995) J. Biol. Chem. 270, 21884-21892.
29. Dunford, H. B. & Hsuanyu, Y. (1999) Biochem. Cell Biol. 77, 449-457.
30. Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A. & Cole, G. M. (2001) J. Neurosci. 21, 8370-8377.
31. Baum, L. & Ng, A. (2004) J. Alzheimer's Dis. 6, 367-377, and discussion 6, 443-449.
32. Sayre, L. M., Perry, G., Harris, P. L., Liu, Y., Schubert, K. A. & Smith, M. A. (2000) J. Neurochem. 74, 270-279.
33. Dwyer, B. E., Takeda, A., Zhu, X., Perry, G. & Smith, M. A. (2005) Curr. Neurovasc. Res. 2, 261-267.
34. Sassa, S. (2004) Antioxid. Redox. Signal 6, 819-824.
35. Scholnick, P. L., Hammaker, L. E. & Marver, H. S. (1972) J. Biol. Chem. 247, 4132-4137.
36. Granick, S. & Sassa, S. (1971) δ-Aminolevulinic Acid Synthetase and the Control of Heme and Chlorophyll Synthesis (Academic, New York).
37. Muller-Eberhard, U., Liem, H. H., Grasso, J. A., Giffhorn-Katz, S., DeFalco, M. G. & Katz, N. R. (1988) J. Biol. Chem. 263, 14753-14756.
38. Iacopetta, B. & Morgan, E. (1984) Biochim. Biophys. Acta 805, 211-216.
39. Smith, M. A., Wehr, K., Harris, P. L., Siedlak, S. L., Connor, J. R. & Perry, G. (1998) Brain Res. 788, 232-236.
40. Atamna, H., Walter, P. B. & Ames, B. N. (2002) Arch. Biochem. Biophys. 397, 345-353.
41. Ignarro, L. J., Ballot, B. & Wood, K. S. (1984) J. Biol. Chem. 259, 6201-6207.
42. Grinstead, G. F., Trzaskos, J. M., Billheimer, J. T. & Gaylor, J. L. (1983) Biochim. Biophys. Acta 751, 41-51.
43. Litman, D. A. & Correia, M. A. (1985) J. Pharmacol. Exp. Ther. 232, 337-345.
44. Fukuyama, R., Mizuno, T., Mon, S., Nakajima, K., Fushiki, S. & Yanagisawa, K. (2000) Eur. Neurol. 43, 155-160.
45. Ames, B. N., Atamna, H. & Killilea, D. W. (2005) Mol. Aspects. Med. 26, 363-378.
46. Ban, T., Hamada, D., Hasegawa, K., Naiki, H. & Goto, Y. (2003) J. Biol. Chem. 278, 16462-16465.
47. Lockhart, A., Ye, L., Judd, D. B., Merritt, A. T., Lowe, P. N., Morgenstern, J. L., Hong, G., Gee, A. D. & Brown, J. (2005) J. Biol. Chem. 280, 7677-7684.
48. Huether, G., Fettkotter, I., Keilhoff, G. & Wolf, G. (1997) J. Neurochem. 69, 2096-2101.
49. Lange, H., Kispal, G. & Lill, R. (1999) J. Biol. Chem. 274, 18989-18996.