DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis

EMBO Molecular Medicine

Volumn 2, Issue 10, 2010, Pages 415-427

  Shao, Lan ^a   Goronzy, Jörg J ^a   Weyand, Cornelia M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; DNA damage; DNA PKcs; Rheumatoid arthritis; T cell

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; DNA DEPENDENT PROTEIN KINASE; PROTEIN P53; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; BMF PROTEIN, HUMAN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; ONCOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADULT; APOPTOSIS; ARTICLE; ATAXIA TELANGIECTASIA; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; FEMALE; GENE SILENCING; GENOTOXICITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; T LYMPHOCYTE; AGED; DRUG ANTAGONISM; ENZYME ACTIVE SITE; IMMUNOLOGICAL TOLERANCE; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ARTHRITIS, RHEUMATOID; CATALYTIC DOMAIN; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; FEMALE; GENE SILENCING; HUMANS; IMMUNE TOLERANCE; MALE; MAP KINASE KINASE 4; MEMBRANE PROTEINS; MIDDLE AGED; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 79952115866     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201000096     Document Type: Article

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