SCOPUS 정보 검색 플랫폼

Volumn 6, Issue 3, 2011, Pages 544-549

1-(3-Biaryloxy-2-oxopropyl)indole-5-carboxylic Acids and Related Compounds as Dual Inhibitors of Human Cytosolic Phospholipase A2α and Fatty Acid Amide Hydrolase

(5) Zahov, Stefan a Drews, Andreas a Hess, Mark a Schulzeelfringhoff, Alwine a Lehr, Matthias a

a UNIVERSITY OF MÜNSTER (Germany)

Author keywords

1 indol 1 yl propan 2 one; Cytosolic phospholipase A2 ; Fatty acid amide hydrolase; Inhibitors; Monoacylglycerol lipase

Indexed keywords

1 [3 [4 (4 FLUOROPHENYL)PHENOXY] 2 OXOPROPYL]INDAZOLE 5 CARBOXYLIC ACID; CARBOXYLIC ACID; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; INDOLE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

AMIDOHYDROLASES; ANALGESICS; ANTI-INFLAMMATORY AGENTS; CARBOXYLIC ACIDS; ENZYME INHIBITORS; GROUP IV PHOSPHOLIPASES A2; HUMANS; INDOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79952078781 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201000473 Document Type: Article

Times cited : (13)

References (35)

1
- 33847638020
- S. P. Khanapure, D. S. Garvey, D. R. Janero, L. G. Letts, Curr. Top. Med. Chem. 2007, 7, 311-340.
- (2007) Curr. Top. Med. Chem. , vol.7 , pp. 311-340
- Khanapure, S.P.¹ Garvey, D.S.² Janero, D.R.³ Letts, L.G.⁴

2
- 65549121665
- J. E. Schlosburg, S. G. Kinsey, A. H. Lichtman, AAPS J. 2009, 11, 39-44.
- (2009) AAPS J. , vol.11 , pp. 39-44
- Schlosburg, J.E.¹ Kinsey, S.G.² Lichtman, A.H.³

3
- 16644382118
- T. Hirabayashi, T. Murayama, T. Shimizu, Biol. Pharm. Bull. 2004, 27, 1168-1173.
- (2004) Biol. Pharm. Bull. , vol.27 , pp. 1168-1173
- Hirabayashi, T.¹ Murayama, T.² Shimizu, T.³

4
- 1342324060
- J. Bonventre, Trends Immunol. 2004, 25, 116-119.
- (2004) Trends Immunol. , vol.25 , pp. 116-119
- Bonventre, J.¹

5
- 33744477349
- M. Lehr, Anti-Inflammatory Anti-Allergy Agents Med. Chem. 2006, 5, 149-161.
- (2006) Anti-Inflammatory Anti-Allergy Agents Med. Chem. , vol.5 , pp. 149-161
- Lehr, M.¹

6
- 73649118166
- V. Magrioti, G. Kokotos, Expert Opin. Ther. Pat. 2010, 20, 1-18.
- (2010) Expert Opin. Ther. Pat. , vol.20 , pp. 1-18
- Magrioti, V.¹ Kokotos, G.²

7
- 0027131849
- L. A. Trimble, I. P. Street, H. Perrier, N. M. Tremblay, P. K. Weech, M. A. Bernstein, Biochemistry 1993, 32, 12560-12565.
- (1993) Biochemistry , vol.32 , pp. 12560-12565
- Trimble, L.A.¹ Street, I.P.² Perrier, H.³ Tremblay, N.M.⁴ Weech, P.K.⁵ Bernstein, M.A.⁶

8
- 0027314633
- I. P. Street, H. K. Lin, F. Laliberte, F. Ghomashchi, Z. Wang, H. Perrier, N. M. Tremblay, Z. Huang, P. K. Weech, M. H. Gelb, Biochemistry 1993, 32, 5935-5940.
- (1993) Biochemistry , vol.32 , pp. 5935-5940
- Street, I.P.¹ Lin, H.K.² Laliberte, F.³ Ghomashchi, F.⁴ Wang, Z.⁵ Perrier, H.⁶ Tremblay, N.M.⁷ Huang, Z.⁸ Weech, P.K.⁹ Gelb, M.H.¹⁰

9
- 0001461456
- Z. Huang, S. Liu, I. Street, F. Laliberte, K. Abdullah, S. Desmarais, Z. Wang, B. Kennedy, P. Payette, D. Riendeau, P. Weech, M. Gresser, Mediators Inflammation 1994, 3, 307-308.
- (1994) Mediators Inflammation , vol.3 , pp. 307-308
- Huang, Z.¹ Liu, S.² Street, I.³ Laliberte, F.⁴ Abdullah, K.⁵ Desmarais, S.⁶ Wang, Z.⁷ Kennedy, B.⁸ Payette, P.⁹ Riendeau, D.¹⁰ Weech, P.¹¹ Gresser, M.¹²

10
- 45749141743
- J. C. McKew, K. L. Lee, M. W. Shen, P. Thakker, M. A. Foley, M. L. Behnke, B. Hu, F. W. Sum, S. Tam, Y. Hu, L. Chen, S. J. Kirincich, R. Michalak, J. Thomason, M. Ipek, K. Wu, L. Wooder, M. K. Ramarao, E. A. Murphy, D. G. Goodwin, L. Albert, X. Xu, F. Donahue, M. S. Ku, J. Keith, C. L. Nickerson-Nutter, W. M. Abraham, C. Williams, M. Hegen, J. D. Clark, J. Med. Chem. 2008, 51, 3388-3413.
- (2008) J. Med. Chem. , vol.51 , pp. 3388-3413
- McKew, J.C.¹ Lee, K.L.² Shen, M.W.³ Thakker, P.⁴ Foley, M.A.⁵ Behnke, M.L.⁶ Hu, B.⁷ Sum, F.W.⁸ Tam, S.⁹ Hu, Y.¹⁰ Chen, L.¹¹ Kirincich, S.J.¹² Michalak, R.¹³ Thomason, J.¹⁴ Ipek, M.¹⁵ Wu, K.¹⁶ Wooder, L.¹⁷ Ramarao, M.K.¹⁸ Murphy, E.A.¹⁹ Goodwin, D.G.²⁰ more..

11
- 0034704801
- K. Seno, T. Okuno, K. Nishi, Y. Murakami, F. Watanabe, T. Matsuura, M. Wada, Y. Fujii, M. Yamada, T. Ogawa, T. Okada, H. Hashizume, M. Kii, S. Hara, S. Hagishita, S. Nakamoto, K. Yamada, Y. Chikazawa, M. Ueno, I. Teshirogi, T. Ono, M. Ohtani, J. Med. Chem. 2000, 43, 1041-1044.
- (2000) J. Med. Chem. , vol.43 , pp. 1041-1044
- Seno, K.¹ Okuno, T.² Nishi, K.³ Murakami, Y.⁴ Watanabe, F.⁵ Matsuura, T.⁶ Wada, M.⁷ Fujii, Y.⁸ Yamada, M.⁹ Ogawa, T.¹⁰ Okada, T.¹¹ Hashizume, H.¹² Kii, M.¹³ Hara, S.¹⁴ Hagishita, S.¹⁵ Nakamoto, S.¹⁶ Yamada, K.¹⁷ Chikazawa, Y.¹⁸ Ueno, M.¹⁹ Teshirogi, I.²⁰ Ono, T.²¹ Ohtani, M.²² more..

12
- 0037075831
- S. Connolly, C. Bennion, S. Botterell, P. J. Croshaw, C. Hallam, K. Hardy, P. Hartopp, C. G. Jackson, S. J. King, L. Lawrence, A. Mete, D. Murray, D. H. Robinson, G. M. Smith, L. Stein, I. Walters, E. Wells, W. J. Withnall, J. Med. Chem. 2002, 45, 1348-1362.
- (2002) J. Med. Chem. , vol.45 , pp. 1348-1362
- Connolly, S.¹ Bennion, C.² Botterell, S.³ Croshaw, P.J.⁴ Hallam, C.⁵ Hardy, K.⁶ Hartopp, P.⁷ Jackson, C.G.⁸ King, S.J.⁹ Lawrence, L.¹⁰ Mete, A.¹¹ Murray, D.¹² Robinson, D.H.¹³ Smith, G.M.¹⁴ Stein, L.¹⁵ Walters, I.¹⁶ Wells, E.¹⁷ Withnall, W.J.¹⁸

13
- 22244484464
- M. K. McKinney, B. F. Cravatt, Annu. Rev. Biochem. 2005, 74, 411-432.
- (2005) Annu. Rev. Biochem. , vol.74 , pp. 411-432
- McKinney, M.K.¹ Cravatt, B.F.²

14
- 34548504316
- G. Labar, C. Michaux, Chem. Biodiversity 2007, 4, 1882-1902.
- (2007) Chem. Biodiversity , vol.4 , pp. 1882-1902
- Labar, G.¹ Michaux, C.²

15
- 58149296562
- F. Fezza, C. DeSimone, D. Amadio, M. Maccarrone, Subcell. Biochem. 2008, 49, 101-132.
- (2008) Subcell. Biochem. , vol.49 , pp. 101-132
- Fezza, F.¹ DeSimone, C.² Amadio, D.³ Maccarrone, M.⁴

16
- 34848863139
- S. M. Saario, J. T. Laitinen, Basic Clin. Pharmacol. Toxicol. 2007, 101, 287-293.
- (2007) Basic Clin. Pharmacol. Toxicol. , vol.101 , pp. 287-293
- Saario, S.M.¹ Laitinen, J.T.²

17
- 67650732783
- K. Ahn, D. S. Johnson, B. F. Cravatt, Expert Opin. Drug Discovery 2009, 4, 763-784.
- (2009) Expert Opin. Drug Discovery , vol.4 , pp. 763-784
- Ahn, K.¹ Johnson, D.S.² Cravatt, B.F.³

18
- 40349114245
- S. Vandevoorde, Curr. Top. Med. Chem. 2008, 8, 247-267.
- (2008) Curr. Top. Med. Chem. , vol.8 , pp. 247-267
- Vandevoorde, S.¹

19
- 77956862617
- H. Deng, Expert Opin. Drug Discovery 2010, 5, 961-993.
- (2010) Expert Opin. Drug Discovery , vol.5 , pp. 961-993
- Deng, H.¹

20
- 0037234363
- S. Kathuria, S. Gaetani, D. Fegley, F. Valino, A. Duranti, A. Tontini, M. Mor, G. Tarzia, G. LaRana, A. Calignano, A. Giustino, M. Tattoli, M. Palmery, V. Cuomo, D. Piomelli, Nat. Med. 2002, 9, 76-81.
- (2002) Nat. Med. , vol.9 , pp. 76-81
- Kathuria, S.¹ Gaetani, S.² Fegley, D.³ Valino, F.⁴ Duranti, A.⁵ Tontini, A.⁶ Mor, M.⁷ Tarzia, G.⁸ LaRana, G.⁹ Calignano, A.¹⁰ Giustino, A.¹¹ Tattoli, M.¹² Palmery, M.¹³ Cuomo, V.¹⁴ Piomelli, D.¹⁵

21
- 12944277105
- D. L. Boger, H. Sato, A. E. Lerner, M. P. Hedrick, R. A. Fecik, H. Miyauchi, G. D. Wilkie, B. J. Austin, M. P. Patricelli, B. F. Cravatt, Proc. Natl. Acad. Sci. USA 2000, 97, 5044-5049.
- (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5044-5049
- Boger, D.L.¹ Sato, H.² Lerner, A.E.³ Hedrick, M.P.⁴ Fecik, R.A.⁵ Miyauchi, H.⁶ Wilkie, G.D.⁷ Austin, B.J.⁸ Patricelli, M.P.⁹ Cravatt, B.F.¹⁰

22
- 0033617291
- A. Dessen, J. Tang, H. Schmidt, M. Stahl, J. D. Clark, J. Seehra, W. S. Somers, Cell 1999, 97, 349-360.
- (1999) Cell , vol.97 , pp. 349-360
- Dessen, A.¹ Tang, J.² Schmidt, H.³ Stahl, M.⁴ Clark, J.D.⁵ Seehra, J.⁶ Somers, W.S.⁷

23
- 44849141696
- K. Ahn, M. K. McKinney, B. F. Cravatt, Chem. Rev. 2008, 108, 1687-1707.
- (2008) Chem. Rev. , vol.108 , pp. 1687-1707
- Ahn, K.¹ McKinney, M.K.² Cravatt, B.F.³

24
- 0031048819
- D. G. Deutsch, R. Omeir, G. Arreaza, D. Salehani, G. D. Prestwich, Z. Huang, A. Howlett, Biochem. Pharmacol. 1997, 53, 255-260.
- (1997) Biochem. Pharmacol. , vol.53 , pp. 255-260
- Deutsch, D.G.¹ Omeir, R.² Arreaza, G.³ Salehani, D.⁴ Prestwich, G.D.⁵ Huang, Z.⁶ Howlett, A.⁷

25
- 0031550564
- L. DePetrocellis, D. Melck, N. Ueda, S. Maurelli, Y. Kurahashi, S. Yamamoto, G. Marino, V. DiMarzo, Biochem. Biophys. Res. Commun. 1997, 231, 82-88.
- (1997) Biochem. Biophys. Res. Commun. , vol.231 , pp. 82-88
- DePetrocellis, L.¹ Melck, D.² Ueda, N.³ Maurelli, S.⁴ Kurahashi, Y.⁵ Yamamoto, S.⁶ Marino, G.⁷ DiMarzo, V.⁸

26
- 0028108312
- B. Koutek, G. D. Prestwich, A. C. Howlett, S. A. Chin, D. Salehani, N. Akhavan, D. G. Deutsch, J. Biol. Chem. 1994, 269, 22937-22940.
- (1994) J. Biol. Chem. , vol.269 , pp. 22937-22940
- Koutek, B.¹ Prestwich, G.D.² Howlett, A.C.³ Chin, S.A.⁴ Salehani, D.⁵ Akhavan, N.⁶ Deutsch, D.G.⁷

27
- 0029619298
- S. Maurelli, T. Bisogno, L. DePetrocellis, A. DiLuccia, G. Marino, V. DiMarzo, FEBS Lett. 1995, 377, 82-86.
- (1995) FEBS Lett. , vol.377 , pp. 82-86
- Maurelli, S.¹ Bisogno, T.² DePetrocellis, L.³ DiLuccia, A.⁴ Marino, G.⁵ DiMarzo, V.⁶

28
- 76449106208
- L. Forster, J. Ludwig, M. Kaptur, S. Bovens, A. Schulze Elfringhoff, A. Holtfrerich, M. Lehr, Bioorg. Med. Chem. 2010, 18, 945-952.
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 945-952
- Forster, L.¹ Ludwig, J.² Kaptur, M.³ Bovens, S.⁴ Elfringhoff, A.S.⁵ Holtfrerich, A.⁶ Lehr, M.⁷

29
- 33947111963
- M. Hess, A. Schulze Elfringhoff, M. Lehr, Bioorg. Med. Chem. 2007, 15, 2883-2891.
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 2883-2891
- Hess, M.¹ Elfringhoff, A.S.² Lehr, M.³

30
- 77954755968
- A. Drews, S. Bovens, K. Roebrock, C. Sunderkötter, D. Reinhardt, M. Schäfers, A. van der Velde, A. Schulze Elfringhoff, J. Fabian, M. Lehr, J. Med. Chem. 2010, 53, 5165-5178.
- (2010) J. Med. Chem. , vol.53 , pp. 5165-5178
- Drews, A.¹ Bovens, S.² Roebrock, K.³ Sunderkötter, C.⁴ Reinhardt, D.⁵ Schäfers, M.⁶ van der Velde, A.⁷ Elfringhoff, A.S.⁸ Fabian, J.⁹ Lehr, M.¹⁰

31
- 63149125026
- S. Bovens, M. Kaptur, A. Schulze Elfringhoff, M. Lehr, Bioorg. Med. Chem. Lett. 2009, 19, 2107-2111.
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 2107-2111
- Bovens, S.¹ Kaptur, M.² Elfringhoff, A.S.³ Lehr, M.⁴

32
- 1642361749
- M. Schmitt, M. Lehr, J. Pharm. Biomed. Anal. 2004, 35, 135-142.
- (2004) J. Pharm. Biomed. Anal. , vol.35 , pp. 135-142
- Schmitt, M.¹ Lehr, M.²

33
- 67650995959
- L. Forster, A. Schulze Elfringhoff, M. Lehr, Anal. Bioanal. Chem. 2009, 394, 1679-1685.
- (2009) Anal. Bioanal. Chem. , vol.394 , pp. 1679-1685
- Forster, L.¹ Elfringhoff, A.S.² Lehr, M.³

34
- 34548514198
- S. M. Saario, J. T. Laitinen, Chem. Biodiversity 2007, 4, 1903-1913.
- (2007) Chem. Biodiversity , vol.4 , pp. 1903-1913
- Saario, S.M.¹ Laitinen, J.T.²

35
- 77049087509
- A. Holtfrerich, T. Makharadze, M. Lehr, Anal. Biochem. 2010, 399, 218-224.
- (2010) Anal. Biochem. , vol.399 , pp. 218-224
- Holtfrerich, A.¹ Makharadze, T.² Lehr, M.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.