Differential phosphorylation of MAPK isoforms in keratinocyte cell line by contact allergens and irritant

Toxicology Mechanisms and Methods

Volumn 17, Issue 2, 2007, Pages 101-107

  Mehrotra, P ^a   Upadhyaya, S ^a   Sinkar, V P ^a   Banerjee, G ^a   Mishra, K P ^b  

^a Hindustan Lever Limited   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Contact Allergy; Irritation; Keratinocytes; MAPK; PKC; Skin

Indexed keywords

ALLERGEN; INTERLEUKIN 12P40; IRRITANT AGENT; MITOGEN ACTIVATED PROTEIN KINASE;

ANTIGEN PRESENTING CELL; ARTICLE; CELL DIFFERENTIATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; KERATINOCYTE; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN ALLERGY;

EID: 33846952883     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510600860250     Document Type: Article

References (25)

1. Aragane, Y., Riemann, H., Bhardwaj, R. S., Schwarz, Y., Sawada, Y., Yamada, H., Luger, T. A., Kubin, M., Trinchieri, G., and Schwarz, T. 1994. IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J. Immunol. 153:5366-5372.
2. Arrighi, J. F., Rebsamen, M., Rousset, F., Kindler, V., and Hauser, C. 2001. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by LPS, TNF and contact sensitizers. J. Immunol. 166:3837-3845.
3. Banerjee, G., Damodaran, A., Devi, N., Dharmalingam, K., and Raman, G. 2004. Role of keratinocytes in antigen presentation and polarization of human T lymphocytes. Scan. J. Immunol. 59:385-394.
4. Banerjee, G., Iyer, V. J., and Cherian, K. M. 2002. A rapid in vitro method to identify contact allergens and irritants. Toxicol. Mech. Methods 13:103-109.
5. Basketter, D. A., and Cadby, P. 2004. Reproducible production of contact allergenic potency using the local lymph node assay. Contact Dermatitis 50:15-17.
6. Boisleve, F., Kerdine-Romer, S., and Pallardy, M. 2005. Implication of the MAPK pathways in thematuration of human dendritic cells induced by nickel and TNF-α. Toxicology 206:233-244.
7. Corsini, E., and Galli, C. L. 2000. Epidermal cytokines in experimental contact dermatitis. Toxicology 142:203-211.
8. Dearman, R. J., Warbrick, E. V., Skinner, R., and Kimber, I. 2002. Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses. Food Chem. Toxicol. 40:1881-1892.
9. Erdmann, G., Saloga, J., Mohamedzadeh, M., Becker, D., Knop, J., and Enk, A. H. 1995. Heat stable antigen is expressed by murine keratinocytes and deliver co-stimulatory signal in T cells activation. Exp. Dermatol. 4:291-296.
10. Hopkins, J. E., Naisbitt, D. J., Kitteringham, N. R., Dearman, R. J., Kimber, I., and Park, B. K. 2005. Selective haptenation of cellular or extracellular protein by chemical allergens: association with cytokine polarisation. Chem. Res. Toxicol. 18:375-381.
11. Hsieh, C.-S., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O'Garra, A., and Murphy, K. M. 1993. Development of Th1CD4+T cells through IL-12 produced by Listeria induced macrophages. Science 260:547-549.
12. Kimber, I., and Cumberbatch, M. 1992. Dendritic cells and cutaneous immune response to chemical allergens. Toxicol. Appl. Pharmacol. 117:137-146.
13. Lisby, S., Muller, M., Jongenee, V., and Saurat, J. H. 1994. Nickel and skin irritants up regulate TNFalpha mRNA in keratinocytes by different but potential synergistic mechanisms. Int. Immunol. 7:343-352.
14. Mathur, R. K., Awasthi, A., Wadhone, P., Ramanamurthy, B., and Saha, B. 2004. Reciprocal CD 40 signals through p38 MAPK and ERk-1/2 induce counteracting immune responses. Nature Med. 10:540-544.
15. Matos, T. J., Duarte, C. B., Goncalo, M., and Lopes, M. C. 2005a. Role of oxidative stress in ERK and p38 MAPK activation induced by chemical sensitizer DNFB in a fetal skin dendritic cell line. Immunol. Cell Biol. 83:607-614.
16. Matos, T. J., Duarte, C. B., Goncalo, M., and Lopes, M. C. 2005b. DNFB activates MAPKs and upregulates CD40 in skin derived dendritic cells. J. Dermatol. Sci. 39:113-123.
17. Mehrotra, P., Mishra, K. P., Raman, G., and Banerjee, G. 2005. Differential regulation of free radicals (reactive oxygen and nitrogen species) by contact allergen and irritants in human keratinocyte cell line. Toxicol. Mech. Methods 15:343-350.
18. Muller, G., Saloga, J., Germann, T., Bellinghausen, I., Mohamadzadeh, M., Knop, J., and Enk, A. H. 1994. Identification and induction of human keratinocyte derived IL-12. J. Clin. Invest. 94:1799-1805.
19. Nakahara, T., Uchi, H., Urabe, K., Chen, O., Furue, M., and Moroi, Y. 2004. Role of JNK on LPS induced maturation of human monocyte derived dendritic cells. Int. Immunol. 16:1701-1709.
20. Pastore, S., Mascia, F., Mariotti, F., Dattilo, C., Mariani, V., and Girolomoni, G. 2005. Erk-1/2 regulates epidermal growth chemokines expression and skin inflammation. J. Immunol. 174:5047-5056.
21. Riemann, H., Schwarz, A., Grabbe, S., Aragane, Y., Lugar, T. A., Wysocka, M., Trincheri, G., and Schwarz, T. 1996. Neutralisation of IL-12 in vivo prevents induction of contact hypersensitivity and induces hapten specific tolerance. J. Immunol. 156:1799-1803.
22. Ruano, M. J., Hernandez-hernando, S., Jimenez, A., Estrada, C., and Villalobo, A. 2003. Nitric oxide induced epidermal growth factor phosphorylation in A431 tumor cells. Eur. J. Biochem. 270:1828-1837.
23. Ryan, C. A., Gerberick, G. F., Gildea, L. A., Hulette, B. C., Betts, C. J., Cumberbatch, M., Dearman, R. J., and Kimber, I. 2005. Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment. Toxicol. Sci. 88:4-11.
24. Takanami, O. Y., Amano, S., Kimura, S., Asada, S., Utani, A., Maruyama, M., and Osada, B. 2002. Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity. J. Biochem. 277:37896-37893.
25. Yamazaki, S., Kuwahara, H., and Kakishima, H. 1997. Analysis of contact dermatitis by cytokine. Yakugaku Zasshi. 117:155-161.