In silico site of metabolism prediction of cytochrome P450-mediated biotransformations

Expert Opinion on Drug Metabolism and Toxicology

Volumn 7, Issue 3, 2011, Pages 299-312

  Tarcsay, Ákos ^a,b   Keserü, György M ^a  

^a GEDEON RICHTER LTD   (Hungary)

^b BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

Author keywords

ADM.E.; computational; CYP

Indexed keywords

CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A13; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 2R1; CYTOCHROME P450 3A4; CYTOCHROME P450 46A1; FLURBIPROFEN; KETOCONAZOLE; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG;

CATALYSIS; COMPUTER MODEL; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME SUBSTRATE; HUMAN; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW;

BIOTRANSFORMATION; COMPUTATIONAL BIOLOGY; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; PHARMACEUTICAL PREPARATIONS;

EID: 79951899664     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.2011.553599     Document Type: Review

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