메뉴 건너뛰기




Volumn 4, Issue 4, 2005, Pages 540-542

PTEN: A novel anti-oncogenic function independent of phosphatase activity

Author keywords

C2 domain; FHA domain; GLTSCR2 PICT1; MSP58; PDZ; PTEN

Indexed keywords

MSP 58 PROTEIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 25444437771     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.4.1614     Document Type: Short Survey
Times cited : (25)

References (26)
  • 1
    • 0034912744 scopus 로고    scopus 로고
    • PTEN and myotubularin: Novel phosphoinositide phosphatases
    • Maehama T, Taylor GS, Dixon JE. PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem 2001; 70:247-9.
    • (2001) Annu Rev Biochem , vol.70 , pp. 247-249
    • Maehama, T.1    Taylor, G.S.2    Dixon, J.E.3
  • 2
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998; 273:13375-8.
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 3
    • 0030728479 scopus 로고    scopus 로고
    • Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
    • USA
    • Furnari FB, Lin H, Huang HS, Cavenee WK. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc Natl Acad Sci USA 1997; 94:12479-84.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 12479-12484
    • Furnari, F.B.1    Lin, H.2    Huang, H.S.3    Cavenee, W.K.4
  • 5
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998; 280:1614-7.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 6
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: One gene, many syndromes
    • Eng C. PTEN: one gene, many syndromes. Hum Mutat 2003; 22:183-98.
    • (2003) Hum Mutat , vol.22 , pp. 183-198
    • Eng, C.1
  • 7
    • 0033946740 scopus 로고    scopus 로고
    • Phosphorylation of the PTEN tail regulates protein stability and function
    • Vazquez F, Ramaswamy S, Nakamura N, Sellers WR. Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 2000; 20:5010-18.
    • (2000) Mol Cell Biol , vol.20 , pp. 5010-5018
    • Vazquez, F.1    Ramaswamy, S.2    Nakamura, N.3    Sellers, W.R.4
  • 8
    • 0033615538 scopus 로고    scopus 로고
    • Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
    • Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 1999; 99:323-34.
    • (1999) Cell , vol.99 , pp. 323-334
    • Lee, J.O.1    Yang, H.2    Georgescu, M.M.3    Di Cristofano, A.4    Maehama, T.5    Shi, Y.6    Dixon, J.E.7    Pandolfi, P.8    Pavletich, N.P.9
  • 9
    • 1242284600 scopus 로고    scopus 로고
    • Regulation of cell migration by the C2 domain of the tumor suppressor PTEN
    • Raftopoulou M, Etienne-Manneville S, Self A, Nicholls S, Hall A. Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science 2004; 303:1179-81.
    • (2004) Science , vol.303 , pp. 1179-1181
    • Raftopoulou, M.1    Etienne-Manneville, S.2    Self, A.3    Nicholls, S.4    Hall, A.5
  • 12
    • 14544282456 scopus 로고    scopus 로고
    • Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor
    • USA
    • Okumura K, Zhao M, Depinho RA, Furnari FB, Cavenee WK. Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc Natl Acad Sci USA 2005; 102:2703-6.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 2703-2706
    • Okumura, K.1    Zhao, M.2    Depinho, R.A.3    Furnari, F.B.4    Cavenee, W.K.5
  • 13
    • 0035829741 scopus 로고    scopus 로고
    • TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1)
    • Bader AG, Schneider ML, Bister K, Hartl M. TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1). Oncogene 2001; 20:7524-35.
    • (2001) Oncogene , vol.20 , pp. 7524-7535
    • Bader, A.G.1    Schneider, M.L.2    Bister, K.3    Hartl, M.4
  • 14
    • 0035793086 scopus 로고    scopus 로고
    • A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt
    • USA
    • Aoki M, Blazek E, Vogt PK. A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt. Proc Natl Acad Sci USA 2004; 98:136-41.
    • (2004) Proc Natl Acad Sci , vol.98 , pp. 136-141
    • Aoki, M.1    Blazek, E.2    Vogt, P.K.3
  • 15
    • 11244250646 scopus 로고    scopus 로고
    • Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness
    • Kotelevets L, van Hengel J, Bruyneel E, Mareel M, van Roy F, Chastre E. Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness. Faseb J 2005; 19:115-7.
    • (2005) Faseb J , vol.19 , pp. 115-117
    • Kotelevets, L.1    Van Hengel, J.2    Bruyneel, E.3    Mareel, M.4    Van Roy, F.5    Chastre, E.6
  • 16
    • 14044261474 scopus 로고    scopus 로고
    • Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein beta-catenin with the scaffolding protein MAGI-2
    • Subauste MC, Nalbant P, Adamson ED, Hahn KM. Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein beta-catenin with the scaffolding protein MAGI-2. J Biol Chem 2005; 280:5676-81.
    • (2005) J Biol Chem , vol.280 , pp. 5676-5681
    • Subauste, M.C.1    Nalbant, P.2    Adamson, E.D.3    Hahn, K.M.4
  • 18
    • 0035945352 scopus 로고    scopus 로고
    • The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
    • Kotelevets L, an Hengel J, Bruyneel E, Mareel M, van Roy F, Chastre E. The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness. J Cell Biol 2001; 155:1129-35.
    • (2001) J Cell Biol , vol.155 , pp. 1129-1135
    • Kotelevets, L.1    An Hengel, J.2    Bruyneel, E.3    Mareel, M.4    Van Roy, F.5    Chastre, E.6
  • 19
    • 0035966127 scopus 로고    scopus 로고
    • Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex
    • Vazquez F, Grossman SR, Takahashi Y, Rokas MV, Nakamura N, Sellers WR. Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex. J Biol Chem 2001; 276:48627-30.
    • (2001) J Biol Chem , vol.276 , pp. 48627-48630
    • Vazquez, F.1    Grossman, S.R.2    Takahashi, Y.3    Rokas, M.V.4    Nakamura, N.5    Sellers, W.R.6
  • 20
    • 0035394373 scopus 로고    scopus 로고
    • Regulation of PTEN binding to MAGI-2 by two putative phosphorylation sites at threonine 382 and 383
    • Rolkacheva T, Boddapati M, Sanfiz A, Tsuchida K, Kimmelman AC, Chan AM. Regulation of PTEN binding to MAGI-2 by two putative phosphorylation sites at threonine 382 and 383. Cancer Res 2001; 61:4985-9.
    • (2001) Cancer Res , vol.61 , pp. 4985-4989
    • Rolkacheva, T.1    Boddapati, M.2    Sanfiz, A.3    Tsuchida, K.4    Kimmelman, A.C.5    Chan, A.M.6
  • 21
    • 0035847102 scopus 로고    scopus 로고
    • The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
    • Torres J, Pulido R. The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation. J Biol Chem 2001; 276:993-8.
    • (2001) J Biol Chem , vol.276 , pp. 993-998
    • Torres, J.1    Pulido, R.2
  • 22
    • 0042232478 scopus 로고    scopus 로고
    • Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: Implications for the control of protein stability and PTEN-protein interactions
    • Torres J, Rodriguez J, Myers MP, Valiente M, Graves JD, Tonks NK, Pulido R. Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: implications for the control of protein stability and PTEN-protein interactions. J Biol Chem 2003; 278:30652-60.
    • (2003) J Biol Chem , vol.278 , pp. 30652-30660
    • Torres, J.1    Rodriguez, J.2    Myers, M.P.3    Valiente, M.4    Graves, J.D.5    Tonks, N.K.6    Pulido, R.7
  • 24
    • 8544256358 scopus 로고    scopus 로고
    • Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein
    • Okahara F, Ikawa H, Kanaho Y, Maehama T. Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein. J Biol Chem 2004; 279:45300-3.
    • (2004) J Biol Chem , vol.279 , pp. 45300-45303
    • Okahara, F.1    Ikawa, H.2    Kanaho, Y.3    Maehama, T.4
  • 25
    • 0031684583 scopus 로고    scopus 로고
    • Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells
    • Bruni R, Roizman B. Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells. J Virol 1998; 72:8525-31.
    • (1998) J Virol , vol.72 , pp. 8525-8531
    • Bruni, R.1    Roizman, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.