Studies on insulin/IGF-1 hybrid and IGF-1 growth-promoting functional region

IUBMB Life

Volumn 49, Issue 4, 2000, Pages 321-325

  Wang, Ping ^a,b   Cai, Ruo Rong ^a   Feng, You Min ^a   Zhang, You Shang ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Growth promoting functional region; Hybrid molecule; IGF 1; Insulin

Indexed keywords

HYBRID PROTEIN; INSULIN; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; MOLECULAR CLONING; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN;

ANIMALIA; SUIDAE;

EID: 0033946267     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540050033203     Document Type: Article

References (19)

1. Humbel, R. E. (1990) Insulin-like growth factors I and II. Eur. J. Biochem. 190, 445-162.
2. Cooke, R. M., Harvey, T. S., and Campbell, I. D. (1991) Solution structure of human insulin-like growth factor I: A nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry 30, 5484-5491.
3. King, G. L., and Kahn, C. R. (1984) The growth effects of insulin. In Growth and Maturation Factors (Guroff, G., ed.), pp. 223-265, John Wiley & Sons, New York.
4. Ullrich, A., Gray, A., Tam, A. W., Yang-Feng, T., Tsubokawaet, M.,Collins, C., Henzel, W., Le Bon, T., Kathuria, S., Chen, E., Jacobs, S., Francke, V, Ramachandran, J., and Fujita-Yamaguchi, Y. (1986) Insulin-like growth factor I receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J. 5, 2503-2512.
5. Katsoyannis, P. G., Schwartz, G. P., Burke, G. T., Joshi, S., Rechler, M. M., Tseng, L. Y.-H. (1987) Insulin-like growth factors: Structure-activity relationships. In Peptide 1986 (Theodoroporlos, D., ed.). pp. 43-60. Walter de Gruyter, Berlin.
6. Cara, J. F., Mirmira. R. G., Nakagawa, S. H., and Tager, H. S. (1990) An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes. J. Biol. Chem. 265, 17820-17825.
7. Tang, Y. H., Cui. H. R., and Feng, Y. M. (1998) Two-chain "insulin/insulin-like growth factor-I" hybrids. Chin. J. Biochem. Biophys. 29, 259-265.
8. Kristensen, C., Andersen, A. S., Hach, M., Wiberg, F. C., Shaffer, L., and Jiedlsen, T. (1995) A single chain insulin-like growth factor I/insulin hybrid with high affinity to the insulin receptor. Biochem. J. 305, 981-986.
9. Bayne, M. L., Applehaum, J., Underwood, D., Chicchi, G. G., Green, B. G., Hayes. N. S., and Cascieri, M. A. (1989) The C region of human insulin-like growth factor (IGF) I is required for high affinity binding to the type 1 IGF receptor. J. Biol. Chem. 264, 11004-11008.
10. Gill, R., Wallach, B., Verma, C., Urso, B., De Wolf, E., Grotzinger, J., Murray-Rust, J., Pitts, J., Wollmer, A., De Meyts, P., and Wood, S. (1996) Engineering the C-region of human insulin-like growth factor-1: Implication for receptor binding. Protein Eng. 9, 1011-1019.
11. Konishi, Y., Kotts, C. E., Bullock, L. D., Tou, J. S., and Johnson, D. A. (1989) Fragments of bovine insulin-like growth factor I and II stimulate proliferation of rat L6 myoblast cells. Biochemstry 28, 8872-8877.
12. Ito, H., Fukuda, Y., Murata, K., and Kimura, A. (1983) Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
13. Tang, Y. H., Liu, W. D., Liu, B., Xu, M. H., Feng, Y. M. (1996) Protein engineering of insulin: A high potential [B10Asp] human insulin. Chin. J. Biochem. 12, 511-515.
14. Zhang, Y. S., Hu, H. M., Cai, R. R., Feng, Y. M., Zhu, S. Q., He, Q. B., Tang, Y. H., Xu, M. H., Xu, Y. G., Zhang, X. T., Liu, B., and Liang, Z. H. (1996) Secretory expression of a single-chain insulin precursor in yeast and its conversion into human insulin. Sci. China (Ser. C) 39, 225-233.
15. Ma, J. G., Li, M. Y., Zheng, J. M., Cui, D. F., Feng, Y. M., and Jing, N. H. (1999) The role of C-terminus of insulin B chain and the amino group of B29 Lys side chain in the growth promoting activities of insulin. Acta Biochem. Biophys. Sin. 31, 274-278.
16. Cascieri, M. A., Chicchi, G. G., Applebaum, J., Hayes, N. S., Green, B. G., and Bayne, M. L. (1988) Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor. Biochemistry 27, 3229-3233.
17. Bayne, M. L., Applebaum, J., Chicchi, G. G., Miller, R. E. (1990) The role of tyrosines 24, 31, and 60 in the high affinity binding of insulin-like growth factor-I to the type 1 insulin-like growth factor receptor. J. Biol. Chem. 265, 15648-15652.
18. Derewenda, U., Derewenda, Z., Dodson, G. G.. and Xiao, B. (1991) X-ray analysis of the single chain B29-Al peptide-linked insulin molecule - a completely inactive analogue. J. Mol. Biol. 220, 425-433.
19. Hua, Q. X., Shoelson, S. E., Kochoyan, M., and Wiess, M. A. (1991) Receptor binding redefined by a structured switch in a mutant human insulin. Nature 354, 238-241.