The interaction between dietary protein and bone health

Journal of Bone and Mineral Metabolism

Volumn 29, Issue 1, 2011, Pages 1-14

  Jesudason, David ^a,b   Clifton, Peter ^a,b  

^a CSIRO   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Bone density; Dietary protein; Fractures

Indexed keywords

BASIC PROTEIN; BIOLOGICAL MARKER; MILK PROTEIN; PHOSPHORUS; SOMATOMEDIN C; SOYBEAN PROTEIN;

ACID BASE BALANCE; BONE DENSITY; BONE MASS; BONE STRENGTH; CALCIUM ABSORPTION; CALCIUM INTAKE; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; FALL RISK ASSESSMENT; FRAGILITY FRACTURE; FRUIT VEGETABLE; HIP FRACTURE; HUMAN; HYPERCALCIURIA; MEAT INDUSTRY; NONHUMAN; NUTRITIONAL REQUIREMENT; OSSIFICATION; OSTEOLYSIS; PH MEASUREMENT; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN DIET; PROTEIN INTAKE; PROTEIN INTERACTION; REVIEW; RISK REDUCTION; SEX DIFFERENCE;

ADOLESCENT; ADULT; AGED; BONE AND BONES; BONE DENSITY; CHILD; DIETARY PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 79951679625     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-010-0225-9     Document Type: Review

References (65)

1. DR Clemmons MM Seek LE Underwood 1985 Supplemental essential amino acids augment the somatomedin-C/insulin-like growth factor I response to refeeding after fasting Metabolism 34 391 395 1:CAS:528:DyaL2MXhsVOqtL4%3D 10.1016/0026-0495(85)90230-6 3884968 (Pubitemid 15066010)
2. Beasley JM, Ichikawa LE, Ange BA, Spangler L, LaCroix AZ, Ott SM, Scholes D (2010) Is protein intake associated with bone mineral density in young women? Am J Clin Nutr 91:1311-1316
3. C Cooper EJ Atkinson DD Hensrud HW Wahner WM O'Fallon BL Riggs LJ Melton 3rd 1996 Dietary protein intake and bone mass in women Calcif Tissue Int 58 320 325 1:CAS:528:DyaK28XivVOnsbY%3D 8661965 (Pubitemid 26136795)
4. JM Lacey JJ Anderson T Fujita Y Yoshimoto M Fukase S Tsuchie GG Koch 1991 Correlates of cortical bone mass among premenopausal and postmenopausal Japanese women J Bone Miner Res 6 651 659 1:STN:280:DyaK38%2FlvVSqtA%3D%3D 10.1002/jbmr.5650060702 1950670
5. K Michaelsson L Holmberg H Mallmin A Wolk R Bergstrom S Ljunghall 1995 Diet, bone mass, and osteocalcin: a cross-sectional study Calcif Tissue Int 57 86 93 1:STN:280:DyaK28%2FnvVCguw%3D%3D 10.1007/BF00298425 7584880
6. D Teegarden RM Lyle GP McCabe LD McCabe WR Proulx K Michon AP Knight CC Johnston CM Weaver 1998 Dietary calcium, protein, and phosphorus are related to bone mineral density and content in young women Am J Clin Nutr 68 749 754 1:CAS:528:DyaK1cXlvFahs7w%3D 9734757 (Pubitemid 28402403)
7. JF Chiu SJ Lan CY Yang PW Wang WJ Yao LH Su CC Hsieh 1997 Long-term vegetarian diet and bone mineral density in postmenopausal Taiwanese women Calcif Tissue Int 60 245 249 1:CAS:528:DyaK2sXhsFKiu7w%3D 10.1007/PL00005812 9069160 (Pubitemid 27106247)
8. JZ Ilich RA Brownbill L Tamborini 2003 Bone and nutrition in elderly women: protein, energy, and calcium as main determinants of bone mineral density Eur J Clin Nutr 57 554 565 1:CAS:528:DC%2BD3sXivFGku7o%3D 10.1038/sj.ejcn. 1601577 12700617 (Pubitemid 36553595)
9. PB Rapuri JC Gallagher V Haynatzka 2003 Protein intake: effects on bone mineral density and the rate of bone loss in elderly women Am J Clin Nutr 77 1517 1525 1:CAS:528:DC%2BD3sXntlamsrg%3D 12791633 (Pubitemid 39655289)
10. PC Jaime R Latorre Mdo AA Florindo T Tanaka CA Zerbini 2006 Dietary intake of Brazilian black and white men and its relationship to the bone mineral density of the femoral neck Sao Paulo Med J 124 267 270 10.1590/S1516- 31802006000500006 17262157 (Pubitemid 46210372)
11. P Kyriazopoulos G Trovas J Charopoulos E Antonogiannakis A Galanos G Lyritis 2006 Lifestyle factors and forearm bone density in young Greek men Clin Endocrinol (Oxf) 65 234 238 1:STN:280:DC%2BD28vmsVarsQ%3D%3D 10.1111/j.1365-2265.2006.02581.x (Pubitemid 44079688)
12. SJ Whiting JL Boyle A Thompson RL Mirwald RA Faulkner 2002 Dietary protein, phosphorus and potassium are beneficial to bone mineral density in adult men consuming adequate dietary calcium J Am Coll Nutr 21 402 409 1:CAS:528:DC%2BD38XotlyqtL4%3D 12356781
13. H Vatanparast DA Bailey AD Baxter-Jones SJ Whiting 2007 The effects of dietary protein on bone mineral mass in young adults may be modulated by adolescent calcium intake J Nutr 137 2674 2679 1:CAS:528:DC%2BD2sXhtlKqtr3J 18029482 (Pubitemid 350255296)
14. G Geinoz CH Rapin R Rizzoli R Kraemer B Buchs D Slosman JP Michel JP Bonjour 1993 Relationship between bone mineral density and dietary intakes in the elderly Osteoporos Int 3 242 248 1:STN:280:DyaK2c%2FgtlOitw%3D%3D 10.1007/BF01623827 8400605 (Pubitemid 23252442)
15. MT Hannan KL Tucker B Dawson-Hughes LA Cupples DT Felson DP Kiel 2000 Effect of dietary protein on bone loss in elderly men and women: the Framingham Osteoporosis Study J Bone Miner Res 15 2504 2512 1:STN:280: DC%2BD3M%2FpsF2kug%3D%3D 10.1359/jbmr.2000.15.12.2504 11127216
16. JH Promislow D Goodman-Gruen DJ Slymen E Barrett-Connor 2002 Protein consumption and bone mineral density in the elderly: the Rancho Bernardo Study Am J Epidemiol 155 636 644 10.1093/aje/155.7.636 11914191 (Pubitemid 34246096)
17. KL Tucker MT Hannan DP Kiel 2001 The acid-base hypothesis: diet and bone in the Framingham Osteoporosis Study Eur J Nutr 40 231 237 1:CAS:528: DC%2BD38XitVGns7g%3D 10.1007/s394-001-8350-8 11842948 (Pubitemid 34093229)
18. MA Schurch R Rizzoli D Slosman L Vadas P Vergnaud JP Bonjour 1998 Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent hip fracture. A randomized, double-blind, placebo-controlled trial Ann Intern Med 128 801 809 1:CAS:528:DyaK1cXjsleltbk%3D 9599191 (Pubitemid 28267712)
19. AL Darling DJ Millward DJ Torgerson CE Hewitt SA Lanham-New 2009 Dietary protein and bone health: a systematic review and meta-analysis Am J Clin Nutr 90 1674 1692 1:CAS:528:DC%2BD1MXhsV2lt7rL 10.3945/ajcn.2009.27799 19889822
20. E Gaffney-Stomberg KL Insogna NR Rodriguez JE Kerstetter 2009 Increasing dietary protein requirements in elderly people for optimal muscle and bone health J Am Geriatr Soc 57 1073 1079 10.1111/j.1532-5415.2009.02285.x 19460090
21. HJ Wengreen RG Munger NA West DR Cutler CD Corcoran J Zhang NE Sassano 2004 Dietary protein intake and risk of osteoporotic hip fracture in elderly residents of Utah J Bone Miner Res 19 537 545 10.1359/JBMR.040208 15005839 (Pubitemid 41071212)
22. D Feskanich WC Willett MJ Stampfer GA Colditz 1996 Protein consumption and bone fractures in women Am J Epidemiol 143 472 479 1:STN:280: DyaK287pvFaltg%3D%3D 8610662 (Pubitemid 26085077)
23. HE Meyer JI Pedersen EB Loken A Tverdal 1997 Dietary factors and the incidence of hip fracture in middle-aged Norwegians. A prospective study Am J Epidemiol 145 117 123 1:STN:280:DyaK2s7lvV2ltQ%3D%3D 9006308 (Pubitemid 27045317)
24. RG Munger JR Cerhan BC Chiu 1999 Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women Am J Clin Nutr 69 147 152 1:CAS:528:DyaK1MXjvFSltQ%3D%3D 9925137 (Pubitemid 29031265)
25. DL Thorpe SF Knutsen WL Beeson S Rajaram GE Fraser 2008 Effects of meat consumption and vegetarian diet on risk of wrist fracture over 25 years in a cohort of peri- and postmenopausal women Public Health Nutr 11 564 572 10.1017/S1368980007000808 17686206 (Pubitemid 351693798)
26. X Zhang XO Shu H Li G Yang Q Li YT Gao W Zheng 2005 Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women Arch Intern Med 165 1890 1895 10.1001/archinte.165.16.1890 16157834 (Pubitemid 41352084)
27. ME Mussolino AC Looker JH Madans JA Langlois ES Orwoll 1998 Risk factors for hip fracture in white men: the NHANES I Epidemiologic Follow-up Study J Bone Miner Res 13 918 924 1:STN:280:DyaK1c3ovF2htg%3D%3D 10.1359/jbmr.1998.13.6.918 9626622 (Pubitemid 28265269)
28. A Wachman DS Bernstein 1968 Diet and osteoporosis Lancet 1 958 959 1:STN:280:DyaF1c3nvFOjsA%3D%3D 10.1016/S0140-6736(68)90908-2 4172759
29. A Sebastian ST Harris JH Ottaway KM Todd RC Morris Jr 1994 Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate N Engl J Med 330 1776 1781 1:STN:280:DyaK2c3kslCrsA%3D%3D 10.1056/NEJM199406233302502 8190153 (Pubitemid 24177612)
30. M Marangella M Di Stefano S Casalis S Berutti P D'Amelio GC Isaia 2004 Effects of potassium citrate supplementation on bone metabolism Calcif Tissue Int 74 330 335 1:CAS:528:DC%2BD2cXjslWrtLo%3D 10.1007/s00223-003-0091-8 15255069 (Pubitemid 38480856)
31. M Thorpe MC Mojtahedi K Chapman-Novakofski E McAuley EM Evans 2008 A positive association of lumbar spine bone mineral density with dietary protein is suppressed by a negative association with protein sulfur J Nutr 138 80 85 1:CAS:528:DC%2BD1cXktVSkug%3D%3D 18156408
32. BA Ince EJ Anderson RM Neer 2004 Lowering dietary protein to U.S. Recommended dietary allowance levels reduces urinary calcium excretion and bone resorption in young women J Clin Endocrinol Metab 89 3801 3807 1:CAS:528:DC%2BD2cXmslKmtLw%3D 10.1210/jc.2003-032016 15292308 (Pubitemid 39071475)
33. U Alexy T Remer F Manz CM Neu E Schoenau 2005 Long-term protein intake and dietary potential renal acid load are associated with bone modeling and remodeling at the proximal radius in healthy children Am J Clin Nutr 82 1107 1114 1:CAS:528:DC%2BD2MXht1ektLfJ 16280446 (Pubitemid 43779772)
34. A Sebastian 2005 Dietary protein content and the diet's net acid load: opposing effects on bone health Am J Clin Nutr 82 921 922 1:CAS:528: DC%2BD2MXht1ektLjF 16280420 (Pubitemid 43779746)
35. RP Heaney DK Layman 2008 Amount and type of protein influences bone health Am J Clin Nutr 87 1567S 1570S 1:CAS:528:DC%2BD1cXmtFehtro%3D 18469289 (Pubitemid 351679812)
36. B Dawson-Hughes SS Harris 2002 Calcium intake influences the association of protein intake with rates of bone loss in elderly men and women Am J Clin Nutr 75 773 779 1:CAS:528:DC%2BD38XisVymtLc%3D 11916767 (Pubitemid 34250693)
37. SA New DJ Millward 2003 Calcium, protein, and fruit and vegetables as dietary determinants of bone health Am J Clin Nutr 77 1340 1341 1:CAS:528:DC%2BD3sXntlamtL8%3D 12716695 author reply 1341 (Pubitemid 44858459)
38. JE Kerstetter KO O'Brien DM Caseria DE Wall KL Insogna 2005 The impact of dietary protein on calcium absorption and kinetic measures of bone turnover in women J Clin Endocrinol Metab 90 26 31 1:CAS:528:DC%2BD2MXlvFentA%3D%3D 10.1210/jc.2004-0179 15546911 (Pubitemid 40116629)
39. AA Lopez-Gonzalez F Grases P Roca B Mari MT Vicente-Herrero A Costa-Bauza 2008 Phytate (myo-inositol hexaphosphate) and risk factors for osteoporosis J Med Food 11 747 752 1:CAS:528:DC%2BD1cXhsVKjtr7E 10.1089/jmf.2008.0087 19053869
40. DL Alekel AS Germain CT Peterson KB Hanson JW Stewart T Toda 2000 Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women Am J Clin Nutr 72 844 852 1:CAS:528:DC%2BD3cXmsFGrt7Y%3D 10966908 (Pubitemid 30667108)
41. BH Arjmandi DA Khalil BJ Smith EA Lucas S Juma ME Payton RA Wild 2003 Soy protein has a greater effect on bone in postmenopausal women not on hormone replacement therapy, as evidenced by reducing bone resorption and urinary calcium excretion J Clin Endocrinol Metab 88 1048 1054 1:CAS:528: DC%2BD3sXit1egur0%3D 10.1210/jc.2002-020849 12629084 (Pubitemid 36337755)
42. BH Arjmandi EA Lucas DA Khalil L Devareddy BJ Smith J McDonald AB Arquitt ME Payton C Mason 2005 One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women Nutr J 4 8 10.1186/1475-2891-4-8 15727682 (Pubitemid 40594714)
43. FS Dalais PR Ebeling D Kotsopoulos BP McGrath HJ Teede 2003 The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women Clin Endocrinol (Oxf) 58 704 709 1:CAS:528: DC%2BD3sXlt12htbk%3D 10.1046/j.1365-2265.2003.01771.x (Pubitemid 36702729)
44. EM Evans SB Racette RE Van Pelt LR Peterson DT Villareal 2007 Effects of soy protein isolate and moderate exercise on bone turnover and bone mineral density in postmenopausal women Menopause 14 481 488 10.1097/01.gme.0000243570. 78570.f7 17213752
45. JC Gallagher R Satpathy K Rafferty V Haynatzka 2004 The effect of soy protein isolate on bone metabolism Menopause 11 290 298 10.1097/01.GME. 0000097845.95550.71 15167308 (Pubitemid 40362183)
46. SC Ho J Woo S Lam Y Chen A Sham J Lau 2003 Soy protein consumption and bone mass in early postmenopausal Chinese women Osteoporos Int 14 835 842 1:CAS:528:DC%2BD3sXosFWrsL8%3D 10.1007/s00198-003-1453-9 12920508 (Pubitemid 37462134)
47. T Horiuchi T Onouchi M Takahashi H Ito H Orimo 2000 Effect of soy protein on bone metabolism in postmenopausal Japanese women Osteoporos Int 11 721 724 1:CAS:528:DC%2BD3cXnsVegtbg%3D 10.1007/s001980070072 11095177
48. DA Khalil EA Lucas S Juma BJ Smith ME Payton BH Arjmandi 2002 Soy protein supplementation increases serum insulin-like growth factor-I in young and old men but does not affect markers of bone metabolism J Nutr 132 2605 2608 1:CAS:528:DC%2BD38XntFOgs7w%3D 12221217 (Pubitemid 35013242)
49. S Kreijkamp-Kaspers L Kok DE Grobbee EH de Haan A Aleman JW Lampe YT van der Schouw 2004 Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial JAMA 292 65 74 1:CAS:528:DC%2BD2cXls1elsL8%3D 10.1001/jama.292.1.65 15238592 (Pubitemid 38923795)
50. KM Newton AZ LaCroix L Levy SS Li P Qu JD Potter JW Lampe 2006 Soy protein and bone mineral density in older men and women: a randomized trial Maturitas 55 270 277 1:CAS:528:DC%2BD28XpvV2ltLk%3D 10.1016/j.maturitas.2006.04. 011 16730418 (Pubitemid 44397353)
51. SM Potter JA Baum H Teng RJ Stillman NF Shay JW Erdman Jr 1998 Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women Am J Clin Nutr 68 1375S 1379S 1:CAS:528:DyaK1cXnvV2gtrY%3D 9848502 (Pubitemid 28550915)
52. ZK Roughead JR Hunt LK Johnson TM Badger GI Lykken 2005 Controlled substitution of soy protein for meat protein: effects on calcium retention, bone, and cardiovascular health indices in postmenopausal women J Clin Endocrinol Metab 90 181 189 1:CAS:528:DC%2BD2MXlvFeksw%3D%3D 10.1210/jc.2004-0393 15483071 (Pubitemid 40116654)
53. PM Vupadhyayula JC Gallagher T Templin SM Logsdon LM Smith 2009 Effects of soy protein isolate on bone mineral density and physical performance indices in postmenopausal women: a 2-year randomized, double-blind, placebo-controlled trial Menopause 16 320 328 10.1097/gme.0b013e3181844893 19169168
54. AZ Budek C Hoppe H Ingstrup KF Michaelsen S Bugel C Molgaard 2007 Dietary protein intake and bone mineral content in adolescents: The Copenhagen Cohort Study Osteoporos Int 18 1661 1667 1:CAS:528:DC%2BD2sXhtF2ht7nI 10.1007/s00198-007-0422-0 17639346 (Pubitemid 47620317)
55. S Aoe T Koyama Y Toba A Itabashi Y Takada 2005 A controlled trial of the effect of milk basic protein (MBP) supplementation on bone metabolism in healthy menopausal women Osteoporos Int 16 2123 2128 1:CAS:528:DC%2BD2MXhtlWkt73J 10.1007/s00198-005-2012-3 16133638 (Pubitemid 41790935)
56. S Aoe Y Toba J Yamamura H Kawakami M Yahiro M Kumegawa A Itabashi Y Takada 2001 Controlled trial of the effects of milk basic protein (MBP) supplementation on bone metabolism in healthy adult women Biosci Biotechnol Biochem 65 913 918 1:CAS:528:DC%2BD3MXjsVagsbc%3D 10.1271/bbb.65.913 11388472 (Pubitemid 33614180)
57. Y Toba Y Takada Y Matsuoka Y Morita M Motouri T Hirai T Suguri S Aoe H Kawakami M Kumegawa A Takeuchi A Itabashi 2001 Milk basic protein promotes bone formation and suppresses bone resorption in healthy adult men Biosci Biotechnol Biochem 65 1353 1357 1:CAS:528:DC%2BD3MXkvFWhsrk%3D 10.1271/bbb.65.1353 11471735 (Pubitemid 33617390)
58. K Uenishi H Ishida Y Toba S Aoe A Itabashi Y Takada 2007 Milk basic protein increases bone mineral density and improves bone metabolism in healthy young women Osteoporos Int 18 385 390 1:CAS:528:DC%2BD2sXhsV2jsro%3D 10.1007/s00198-006-0228-5 17048062 (Pubitemid 46233185)
59. J Yamamura S Aoe Y Toba M Motouri H Kawakami M Kumegawa A Itabashi Y Takada 2002 Milk basic protein (MBP) increases radial bone mineral density in healthy adult women Biosci Biotechnol Biochem 66 702 704 1:CAS:528: DC%2BD38Xisl2lsr4%3D 10.1271/bbb.66.702 12005077 (Pubitemid 39251039)
60. ZY Zou XM Lin XR Xu R Xu L Ma Y Li MF Wang 2009 Evaluation of milk basic protein supplementation on bone density and bone metabolism in Chinese young women Eur J Nutr 48 301 306 1:CAS:528:DC%2BD1MXptVGit70%3D 10.1007/s00394-009- 0014-1 19296044
61. LA Frassetto KM Todd RC Morris Jr A Sebastian 2000 Worldwide incidence of hip fracture in elderly women: relation to consumption of animal and vegetable foods J Gerontol A Biol Sci Med Sci 55 M585 M592 1:STN:280: DC%2BD3cvosFGksw%3D%3D 11034231
62. C Weikert D Walter K Hoffmann A Kroke MM Bergmann H Boeing 2005 The relation between dietary protein, calcium and bone health in women: results from the EPIC-Potsdam cohort Ann Nutr Metab 49 312 318 1:CAS:528: DC%2BD2MXpvFGrtbw%3D 10.1159/000087335 16088096 (Pubitemid 41291554)
63. DE Sellmeyer KL Stone A Sebastian SR Cummings 2001 A high ratio of dietary animal to vegetable protein increases the rate of bone loss and the risk of fracture in postmenopausal women. Study of Osteoporotic Fractures Research Group Am J Clin Nutr 73 118 122 1:CAS:528:DC%2BD3MXitVSrsw%3D%3D 11124760 (Pubitemid 32016825)
64. A Sebastian DE Sellmeyer KL Stone SR Cummings 2001 Dietary ratio of animal to vegetable protein and rate of bone loss and risk of fracture in postmenopausal women Am J Clin Nutr 74 411 412 1:STN:280:DC%2BD3MvpsFSmug%3D%3D 11522569 (Pubitemid 32802029)
65. ZK Roughead LK Johnson GI Lykken JR Hunt 2003 Controlled high meat diets do not affect calcium retention or indices of bone status in healthy postmenopausal women J Nutr 133 1020 1026 1:CAS:528:DC%2BD3sXivVekur8%3D 12672913 (Pubitemid 36407119)