메뉴 건너뛰기




Volumn 62, Issue 4, 2010, Pages 367-376

Effects of Korean white ginseng extracts on obesity in highfat diet-induced obese mice

Author keywords

High fat diet induced obese mice; Intestinal fat absorption; Korean white ginseng; Lipogenesis related genes

Indexed keywords

DIACYLGLYCEROL ACYLTRANSFERASE 1; FATTY ACID SYNTHASE; GINSENG EXTRACT; LEPTIN; LIPID EMULSION; LIPOPROTEIN LIPASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL;

EID: 79951604849     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-010-9288-7     Document Type: Conference Paper
Times cited : (43)

References (46)
  • 1
    • 34247556686 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • Ahima RS (2006) Adipose tissue as an endocrine organ. Obesity 14:242S-249S
    • (2006) Obesity , vol.14
    • Ahima, R.S.1
  • 2
    • 0027979143 scopus 로고
    • Obesity as an adaptation to a high-fat diet: Evidence from across-sectional study
    • Astrup A, Buemann B, Western P et al (1994) Obesity as an adaptation to a high-fat diet: evidence from across-sectional study. Am J Clin Nutr 59:350-355
    • (1994) Am J Clin Nutr , vol.59 , pp. 350-355
    • Astrup, A.1    Buemann, B.2    Western, P.3
  • 3
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: Multiple constituents and multiple actions
    • DOI 10.1016/S0006-2952(99)00212-9, PII S0006295299002129
    • Attele AS, Wu JA, Yuan CS (1999) Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol 58:1685-1693 (Pubitemid 29505408)
    • (1999) Biochemical Pharmacology , vol.58 , Issue.11 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.-S.3
  • 5
    • 0039379120 scopus 로고    scopus 로고
    • Obesity
    • DOI 10.1016/S0140-6736(97)04503-0
    • Björntorp P (1997) Obesity. Lancet 350:423-426 (Pubitemid 27331604)
    • (1997) Lancet , vol.350 , Issue.9075 , pp. 423-426
    • Bjorntorp, P.1
  • 6
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • DOI 10.1016/S0092-8674(00)80213-5
    • Brown MS, Goldstein JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340 (Pubitemid 27220877)
    • (1997) Cell , vol.89 , Issue.3 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 0034468978 scopus 로고    scopus 로고
    • DGAT and triglyceride synthesis: A new target for obesity treatment?
    • DOI 10.1016/S1050-1738(00)00066-9, PII S1050173800000669
    • Chen HC, Farese RV Jr (2000) DGAT and triglyceride synthesis: a new target for obesity treatment? Trends Cardiovasc Med 10:188-192 (Pubitemid 32229886)
    • (2000) Trends in Cardiovascular Medicine , vol.10 , Issue.5 , pp. 188-192
    • Chen, H.C.1    Farese Jr., R.V.2
  • 8
    • 14744304497 scopus 로고    scopus 로고
    • Inhibition of triglyceride synthesis as a treatment strategy for obesity: Lessons from DGAT1-deficient mice
    • DOI 10.1161/01.ATV.0000151874.81059.ad
    • Chen HC, Farese RV Jr (2005) Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice. Arterioscler Thromb Vasc Biol 25:482-486 (Pubitemid 40330925)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.3 , pp. 482-486
    • Chen, H.C.1    Farese Jr., R.V.2
  • 9
    • 34250217074 scopus 로고    scopus 로고
    • A water-soluble extract from Cucurbita moschata shows anti-obesity effects by controlling lipid metabolism in a high fat diet-induced obesity mouse model
    • DOI 10.1016/j.bbrc.2007.05.107, PII S0006291X0701056X
    • Choi H, Eo H, Park K (2007) A water-soluble extract from Cucurbita moschata shows anti-obesity effects by controlling lipid metabolism in a high fat diet-induced obesity mouse model. Biochem Biophys Res Commun 359:419-425 (Pubitemid 46898967)
    • (2007) Biochemical and Biophysical Research Communications , vol.359 , Issue.3 , pp. 419-425
    • Choi, H.1    Eo, H.2    Park, K.3    Jin, M.4    Park, E.-J.5    Kim, S.-H.6    Park, J.E.7    Kim, S.8
  • 10
    • 0035380884 scopus 로고    scopus 로고
    • Comparisons between white ginseng radix and rootlet for antidiabetic activity and mechanism in KKAy mice
    • Chung SH, Choi CG, Park SH (2001) Comparisons between white ginseng radix and rootlet for antidiabetic activity and mechanism in KKAy mice. Arch Pharm Res 24:214-218 (Pubitemid 33703564)
    • (2001) Archives of Pharmacal Research , vol.24 , Issue.3 , pp. 214-218
    • Chung, S.H.1    Choi, C.G.2    Park, S.-H.3
  • 11
    • 0034047295 scopus 로고    scopus 로고
    • Obesity: What mental health professionals need to know
    • DOI 10.1176/appi.ajp.157.6.854
    • Devlin MJ, Yanovski SZ, Wilson GT (2000) Obesity: what mental health professionals need to know. Am J Psychiatry 157:854-866 (Pubitemid 30412334)
    • (2000) American Journal of Psychiatry , vol.157 , Issue.6 , pp. 854-866
    • Devlin, M.J.1    Yanovski, S.Z.2    Wilson, G.T.3
  • 12
    • 0024500560 scopus 로고
    • Lipoprotein lipase: A multifunctional enzyme relevant to common metabolic diseases
    • Eckel R (1989) Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic disease. N Engl J Med 320:1060-1068 (Pubitemid 19105751)
    • (1989) New England Journal of Medicine , vol.320 , Issue.16 , pp. 1060-1068
    • Eckel, R.H.1
  • 13
  • 15
    • 1842521023 scopus 로고    scopus 로고
    • Management of obesity as a chronic disease: Nonpharmacologic, pharmacologic, and surgical options
    • Fujioka K (2002) Management of obesity as a chronic disease: nonpharmacologic, pharmacologic, and surgical options. Obes Res 10:116S-123S (Pubitemid 41132565)
    • (2002) Obesity Research , vol.10 , Issue.SUPPL. 2
    • Fujioka, K.1
  • 17
    • 0036322011 scopus 로고    scopus 로고
    • Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice
    • Han LK, Zheng YN, Xu BJ et al (2002) Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice. J Nutr 132:2241-2245
    • (2002) J Nutr , vol.132 , pp. 2241-2245
    • Han, L.K.1    Zheng, Y.N.2    Xu, B.J.3
  • 18
    • 25444499714 scopus 로고    scopus 로고
    • Anti-obesity effects of chikusetsusaponins isolated from Panax japonicus rhizomes
    • Han LK, Zheng YN, Yoshikawa M et al (2005) Anti-obesity effects of chikusetsusaponins isolated from Panax japonicus rhizomes. BMC Complement Altern Med 5:9
    • (2005) BMC Complement Altern Med , vol.5 , pp. 9
    • Han, L.K.1    Zheng, Y.N.2    Yoshikawa, M.3
  • 19
    • 0025264030 scopus 로고
    • Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings
    • Hernell O, Staggers JE, Carey MC (1990) Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. Biochemistry 29:2041-2056 (Pubitemid 20085429)
    • (1990) Biochemistry , vol.29 , Issue.8 , pp. 2041-2056
    • Hernell, O.1    Staggers, J.E.2    Carey, M.C.3
  • 20
    • 38049123030 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats
    • Huang HL, Hong YW, Wong YH et al (2008) Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats. Br J Nutr 99:230-239
    • (2008) Br J Nutr , vol.99 , pp. 230-239
    • Huang, H.L.1    Hong, Y.W.2    Wong, Y.H.3
  • 22
    • 59449086814 scopus 로고    scopus 로고
    • Anti-obesity effect of ginsenoside Rg3 involves the AMPK and PPAR-g signal pathways
    • Hwang JT, Lee MS, Kim HJ et al (2009) Anti-obesity effect of ginsenoside Rg3 involves the AMPK and PPAR-g signal pathways. Phytother Res 23:262-266
    • (2009) Phytother Res , vol.23 , pp. 262-266
    • Hwang, J.T.1    Lee, M.S.2    Kim, H.J.3
  • 23
    • 34547791216 scopus 로고    scopus 로고
    • Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats
    • DOI 10.1016/j.jep.2007.06.022, PII S0378874107003121
    • Ji W, Gong BQ (2007) Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rat. J Ethonopharmacol 113:318-324 (Pubitemid 47239259)
    • (2007) Journal of Ethnopharmacology , vol.113 , Issue.2 , pp. 318-324
    • Ji, W.1    Gong, B.Q.2
  • 24
    • 34247611292 scopus 로고    scopus 로고
    • Weight gain reduction in mice fed Panax ginseng saponin, a pancreatic lipase inhibitor
    • DOI 10.1021/jf0628025
    • Karu N, Reifen R, Kerem Z (2007) Weight gain reduction in mice fed Panax ginseng saponin, a pancreatic lipase inhibitor. J Agric Food Chem 55:2824-2828 (Pubitemid 46668284)
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , Issue.8 , pp. 2824-2828
    • Karu, N.1    Reifen, R.2    Kerem, Z.3
  • 26
    • 0033636847 scopus 로고    scopus 로고
    • High-fat dietinduced muscle insulin resistance: Relationship to visceral fat mass
    • Kim JY, Nolte LA, Hansen PA et al (2000) High-fat dietinduced muscle insulin resistance: relationship to visceral fat mass. Am J Physiol Regul Integr Comp Physiol 27:R2057-R2065
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.27
    • Kim, J.Y.1    Nolte, L.A.2    Hansen, P.A.3
  • 28
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman PG (2000) Obesity as a medical problem. Nature 404:635-643 (Pubitemid 30205068)
    • (2000) Nature , vol.404 , Issue.6778 , pp. 635-643
    • Kopelman, P.G.1
  • 29
    • 0037088683 scopus 로고    scopus 로고
    • Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
    • DOI 10.1074/jbc.M111421200
    • Liang G, Yang J, Horton JD et al (2002) Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem 277:9520-9528 (Pubitemid 34953041)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.11 , pp. 9520-9528
    • Liang, G.1    Yang, J.2    Horton, J.D.3    Hammer, R.E.4    Goldstein, J.L.5    Brown, M.S.6
  • 30
    • 59449090299 scopus 로고    scopus 로고
    • Antiobesity effects of wild ginseng (Panax ginseng C.A. Meyer) mediated by PPAR-gamma, GLUT4 and LPL in ob/ob mice
    • Mollah ML, Kim GS, Moon HK et al (2009) Antiobesity effects of wild ginseng (Panax ginseng C.A. Meyer) mediated by PPAR-gamma, GLUT4 and LPL in ob/ob mice. Phytother Res 23:220-225
    • (2009) Phytother Res , vol.23 , pp. 220-225
    • Mollah, M.L.1    Kim, G.S.2    Moon, H.K.3
  • 32
    • 0032475889 scopus 로고    scopus 로고
    • Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins
    • Pai JT, Guryev O, Brown MS et al (1998) Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins. J Biol Chem 273:26138-26148
    • (1998) J Biol Chem , vol.273 , pp. 26138-26148
    • Pai, J.T.1    Guryev, O.2    Brown, M.S.3
  • 33
    • 26444562863 scopus 로고    scopus 로고
    • Effects of dietary mulberry, Korean red ginseng and banaba on glucose homeostasis in relation to PPAR-alpha, PPAR-gamma, and LPL mRNA expressions
    • Park MY, Lee KS, Sung MK (2005) Effects of dietary mulberry, Korean red ginseng and banaba on glucose homeostasis in relation to PPAR-alpha, PPAR-gamma, and LPL mRNA expressions. Life Sci 77:3344-3354
    • (2005) Life Sci , vol.77 , pp. 3344-3354
    • Park, M.Y.1    Lee, K.S.2    Sung, M.K.3
  • 34
    • 56749161352 scopus 로고    scopus 로고
    • Ginsenosides Rb1 and Rg1 suppress triglyceride accumulation in 3T3-L1 adipocytes and enhances β-cell insulin secretion and viability in Min6 Cells via PKA-dependent pathways
    • Park S, Ahn IS, Kwon DY et al (2008) Ginsenosides Rb1 and Rg1 suppress triglyceride accumulation in 3T3-L1 adipocytes and enhances β-cell insulin secretion and viability in Min6 Cells via PKA-dependent pathways. Biosci Biotechnol Biochem 72:2815-2823
    • (2008) Biosci Biotechnol Biochem , vol.72 , pp. 2815-2823
    • Park, S.1    Ahn, I.S.2    Kwon, D.Y.3
  • 35
    • 0031037111 scopus 로고    scopus 로고
    • Regulation of adipose cell number in man
    • Prins JB, O'Rahilly S (1997) Regulation of adipose cell number in man. Clin Sci 92:3-11 (Pubitemid 27033005)
    • (1997) Clinical Science , vol.92 , Issue.1 , pp. 3-11
    • Prins, J.B.1    O'Rahilly, S.2
  • 38
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spieglman BM, Filer JS (2001) Obesity and the regulation of energy balance. Cell 104:531-543
    • (2001) Cell , vol.104 , pp. 531-543
    • Spieglman, B.M.1    Filer, J.S.2
  • 39
    • 0002175277 scopus 로고
    • Pancreatic lipase
    • Borgstrom B, Brockman HL (eds), Elevier, Amsterdam
    • Verger R (1984) Pancreatic lipase. In: Borgstrom B, Brockman HL (eds) Lipase. Elevier, Amsterdam, pp 83-105
    • (1984) Lipase , pp. 83-105
    • Verger, R.1
  • 42
    • 0032871676 scopus 로고    scopus 로고
    • Nutrition in the intensive care unit
    • Weissman C (1999) Nutrition in the intensive care unit. Crit Care 3:67-75
    • (1999) Crit Care , vol.3 , pp. 67-75
    • Weissman, C.1
  • 43
    • 0020988546 scopus 로고
    • Plasma lipidlowering action of ginseng saponins and mechanism of the action
    • Yamamoto M, Kugami A, Yamamura Y (1983) Plasma lipidlowering action of ginseng saponins and mechanism of the action. Am J Chin Med 11:84-87
    • (1983) Am J Chin Med , vol.11 , pp. 84-87
    • Yamamoto, M.1    Kugami, A.2    Yamamura, Y.3
  • 44
    • 34748910088 scopus 로고    scopus 로고
    • Dietary chickpeas reverse visceral adiposity, dyslipidaemia and insulin resistance in rats induced by a chronic high-fat diet
    • DOI 10.1017/S0007114507750870, PII S0007114507750870
    • Yang Y, Zhou L, Gu Y (2007) Dietary chickpeas reverse visceral adiposity, dyslipidaemia and insulin resistance in rats induced by a chronic high-fat diet. Br J Nutr 98: 720-726 (Pubitemid 47487938)
    • (2007) British Journal of Nutrition , vol.98 , Issue.4 , pp. 720-726
    • Yang, Y.1    Zhou, L.2    Gu, Y.3    Zhang, Y.4    Tang, J.5    Li, F.6    Shang, W.7    Jiang, B.8    Yue, X.9    Chen, M.10
  • 46
    • 16644380244 scopus 로고    scopus 로고
    • Wild ginseng prevents the onset of high-fat diet induced hyperglycemia and obesity in ICR mice
    • Yun SN, Moon SJ, Ko SK et al (2004) Wild ginseng prevents the onset of high-fat diet induced hyperglycemiaand obesity in ICR mice. Arch Pharm Res 27:790-796 (Pubitemid 43086225)
    • (2004) Archives of Pharmacal Research , vol.27 , Issue.7 , pp. 790-796
    • Yun, S.N.1    Moon, S.J.2    Ko, S.K.3    Im, B.O.4    Chung, S.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.