Discovery of novel cyanamide-based inhibitors of cathepsin C

ACS Medicinal Chemistry Letters

Volumn 2, Issue 2, 2011, Pages 142-147

  Lainé, Dramane ^a   Palovich, Michael ^a   McCleland, Brent ^a   Petitjean, Emilie ^a   Delhom, Isabelle ^a   Xie, Haibo ^a   Deng, Jianghe ^a   Lin, Guoliang ^a   Davis, Roderick ^a   Jolit, Anais ^a   Nevins, Neysa ^a   Zhao, Baoguang ^a   Villa, Jim ^a   Schneck, Jessica ^a   McDevitt, Patrick ^a   Midgett, Robert ^a   Kmett, Casey ^a   Umbrecht, Sandra ^a   Peck, Brian ^a   Davis, Alicia Bacon ^a   Bettoun, David ^a   more..

^a GLAXOSMITHKLINE   (United States)

Author keywords

Cathepsin C inhibitors; cigarette smoke; cyanamides; potent; selective

Indexed keywords

CYANAMIDE; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDYL PEPTIDASE I INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

EID: 79951519893     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml100212k     Document Type: Article

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