Novel and potent cyclic cyanamide-based cathepsin K inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 7, 2005, Pages 1815-1819

  Deaton, David N ^a   Hassell, Anne M ^a   McFadyen, Robert B ^a   Miller, Aaron B ^a   Miller, Larry R ^a   Shewchuk, Lisa M ^a   Tavares, Francis X ^a   Willard Jr , Derril H ^a   Wright, Lois L ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Cathepsin K; Cyanamide; Cysteine protease inhibitor; Warhead

Indexed keywords

CATHEPSIN K INHIBITOR; CYANAMIDE; PHOSPHODIESTERASE IV INHIBITOR; PYRROLIDINE DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; X RAY ANALYSIS;

EID: 15044351879     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.033     Document Type: Article

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