Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure

Circulation

Volumn 123, Issue 4, 2011, Pages 391-399

  Damilano, Federico ^a   Franco, Irene ^a   Perrino, Cinzia ^b   Schaefer, Katrin ^c   Azzolino, Ornella ^a   Carnevale, Daniela ^b   Cifelli, Giuseppe ^b   Carullo, Pierluigi ^b   Ragona, Riccardo ^a   Ghigo, Alessandra ^a   Perino, Alessia ^d   Lembo, Giuseppe ^b   Hirsch, Emilio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b IRCCS NEUROMED   (Italy)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

fibrosis; heart failure; inflammation; PI3K ; signal transduction

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE GAMMA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BONE MARROW CELL; CELL INFILTRATION; CELL TYPE; CHIMERA; CONTROLLED STUDY; DIASTOLE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE TARGETING; GENOTYPE; HEART DILATATION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART PROTECTION; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE;

ANIMALS; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; FIBROSIS; GENE KNOCK-IN TECHNIQUES; HEART; HEART FAILURE; LEUKOCYTES; MICE; MICE, INBRED C57BL; MYOCARDIUM; VENTRICULAR REMODELING;

EID: 79751524816     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.110.950543     Document Type: Article

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