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Volumn 16, Issue 1, 2011, Pages 37-42

Wilms' tumor protein and FLT3-internal tandem duplication expression in patients with de novo acute myeloid leukemia

Author keywords

Acute myeloid leukemia; FLT3 ITD; Wilms' tumor protein

Indexed keywords

CD135 ANTIGEN; CYTARABINE; EPIRUBICIN; ETOPOSIDE; IDARUBICIN; MOLECULAR MARKER; WT1 PROTEIN;

EID: 79551711403     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453311X12902908411913     Document Type: Article
Times cited : (14)

References (36)
  • 1
    • 0030955875 scopus 로고    scopus 로고
    • The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells
    • DOI 10.1016/S0014-5793(97)00477-8, PII S0014579397004778
    • Murata Y, Kudoh T, Sugiyama H, Toyoshima K, Akiyama T. The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells. FEBS Lett 1997;409:41-5. (Pubitemid 27248563)
    • (1997) FEBS Letters , vol.409 , Issue.1 , pp. 41-45
    • Murata, Y.1    Kudoh, T.2    Sugiyama, H.3    Toyoshima, K.4    Akiyama, T.5
  • 3
    • 0029164446 scopus 로고
    • The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis
    • Maheswaran S, Englert C, Bennett P, Heinrich G, Haber DA. The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis. Genes Dev 1995;9:2143-65.
    • (1995) Genes Dev , vol.9 , pp. 2143-2165
    • Maheswaran, S.1    Englert, C.2    Bennett, P.3    Heinrich, G.4    Haber, D.A.5
  • 4
    • 0033565656 scopus 로고    scopus 로고
    • WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene
    • MayoMW,Wang CY,Drouin SS, Madrid LV,MarshallAF, Reed JC, et al. WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene. EMBO J 1999;18:3990-4003.
    • (1999) EMBO J , vol.18 , pp. 3990-4003
    • Mayo, M.W.1    Wang, C.Y.2    Drouin, S.S.3    Madrid, L.V.4    Marshall, A.F.5    Reed, J.C.6
  • 5
    • 0033169732 scopus 로고    scopus 로고
    • The role of Wilms' tumor genes
    • Hirose M. The role of Wilms' tumor genes. J Med Invest 1999;46:130-40.
    • (1999) J Med Invest , vol.46 , pp. 130-140
    • Hirose, M.1
  • 6
    • 0029941043 scopus 로고    scopus 로고
    • The WT1 Wilms' tumor suppressor gene: How much do we really know?
    • Reddy JC, Licht JD. The WT1 Wilms' tumor suppressor gene: how much do we really know? Biochim Biophys Acta 1996;1287:1-28.
    • (1996) Biochim Biophys Acta , vol.1287 , pp. 1-28
    • Reddy, J.C.1    Licht, J.D.2
  • 7
    • 0026751042 scopus 로고
    • Expression of the Wilms' tumor gene (WT1) in human leukemias
    • Miwa H, Beran M, Saunders GF. Expression of the Wilms' tumor gene (WT1) in human leukemias. Leukemia 1992;6:405-9.
    • (1992) Leukemia , vol.6 , pp. 405-409
    • Miwa, H.1    Beran, M.2    Saunders, G.F.3
  • 8
    • 0028606895 scopus 로고
    • The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells
    • Brieger J, Weidmann E, Fenchel K, Mitrou PS, Hoelzer D, Bergmann L. The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells. Leukemia 1994;8:2138-43.
    • (1994) Leukemia , vol.8 , pp. 2138-2143
    • Brieger, J.1    Weidmann, E.2    Fenchel, K.3    Mitrou, P.S.4    Hoelzer, D.5    Bergmann, L.6
  • 9
    • 0028811234 scopus 로고
    • The Wilms' tumor gene is frequently expressed in acute myeloblastic leukemias and may provide a marker for residual blast cells detectable by PCR
    • Brieger J, Weidmann E, Maurer U, Hoelzer D, Mitrou PS, Bergmann L. The Wilms' tumor gene is frequently expressed in acute myeloblastic leukemias and may provide a marker for residual blast cells detectable by PCR. Ann Oncol 1995;6:811-6.
    • (1995) Ann Oncol , vol.6 , pp. 811-816
    • Brieger, J.1    Weidmann, E.2    Maurer, U.3    Hoelzer, D.4    Mitrou, P.S.5    Bergmann, L.6
  • 10
    • 0030737629 scopus 로고    scopus 로고
    • High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome
    • Bergmann L, Miething C, Maurer U, Brieger J, Karakas T, Weidmann E, et al. High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome. Blood 1997;90:1217-25.
    • (1997) Blood , vol.90 , pp. 1217-1225
    • Bergmann, L.1    Miething, C.2    Maurer, U.3    Brieger, J.4    Karakas, T.5    Weidmann, E.6
  • 11
    • 0028130136 scopus 로고
    • WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia
    • Inoue K, Sugiyama H, Ogawa H, Nakagawa M, Yamagami T, Miwa H, et al. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 1994;84:3071-9.
    • (1994) Blood , vol.84 , pp. 3071-3079
    • Inoue, K.1    Sugiyama, H.2    Ogawa, H.3    Nakagawa, M.4    Yamagami, T.5    Miwa, H.6
  • 12
    • 3943088995 scopus 로고    scopus 로고
    • Prognostic implications of Wilms' tumor gene (WT1) expression in patients with de novo acute myeloid leukemia
    • Barragán E, Cervera J, Bolufer P, Ballester S, Martín G, Fernández P, et al. Prognostic implications of Wilms' tumor gene (WT1) expression in patients with de novo acute myeloid leukemia. Haematologica 2004;89:926-33.
    • (2004) Haematologica , vol.89 , pp. 926-933
    • Barragán, E.1    Cervera, J.2    Bolufer, P.3    Ballester, S.4    Martín, G.5    Fernández, P.6
  • 13
    • 0032519768 scopus 로고    scopus 로고
    • C-Kit ligand and Flt3 ligand: Stem/progenitor cell factors with overlapping yet distinct activities
    • Lyman SD, Jacobsen SE. c-Kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities. Blood 1998;91:1101-34.
    • (1998) Blood , vol.91 , pp. 1101-1134
    • Lyman, S.D.1    Jacobsen, S.E.2
  • 15
    • 0027931013 scopus 로고
    • Genomic structure of the downstream part of the human FLT3 gene: Exon/ intron structure conservation among genes encoding receptor tyrosine kinases (RTK) of subclass III
    • Agne's F, Shamoon B, Dina C, Rosnet O, Birnbaum D, Galibert F. Genomic structure of the downstream part of the human FLT3 gene: exon/ intron structure conservation among genes encoding receptor tyrosine kinases (RTK) of subclass III. Gene 1994;145:283-8.
    • (1994) Gene , vol.145 , pp. 283-288
    • Agne's, F.1    Shamoon, B.2    Dina, C.3    Rosnet, O.4    Birnbaum, D.5    Galibert, F.6
  • 16
    • 0030002950 scopus 로고    scopus 로고
    • Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells
    • Drexler HG. Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells. Leukemia 1996;10:588-99.
    • (1996) Leukemia , vol.10 , pp. 588-599
    • Drexler, H.G.1
  • 18
    • 0034040255 scopus 로고    scopus 로고
    • Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene
    • Rombouts WJ, Blokland I, Löwenberg B, Ploemacher RE. Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene. Leukemia 2000;14:675-83.
    • (2000) Leukemia , vol.14 , pp. 675-683
    • Rombouts, W.J.1    Blokland, I.2    Löwenberg, B.3    Ploemacher, R.E.4
  • 19
    • 0033758958 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group
    • Abu-Duhier FM, Goodeve AC, Wilson GA, Gari MA, Peake IR, Rees DC, et al. FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group. Br J Haematol 2000;111:190-5.
    • (2000) Br J Haematol , vol.111 , pp. 190-195
    • Abu-Duhier, F.M.1    Goodeve, A.C.2    Wilson, G.A.3    Gari, M.A.4    Peake, I.R.5    Rees, D.C.6
  • 21
    • 0042527742 scopus 로고    scopus 로고
    • Risk-adapted postremission therapy in acute myeloid leukemia: Results of the German multicenter AML HD93 treatment trial
    • Schlenk RF, Benner A, Hartmann F, del Valle F, Weber C, Pralle H, et al. Risk-adapted postremission therapy in acute myeloid leukemia: results of the German multicenter AML HD93 treatment trial. Leukemia 2003;17:1521-8.
    • (2003) Leukemia , vol.17 , pp. 1521-1528
    • Schlenk, R.F.1    Benner, A.2    Hartmann, F.3    Del Valle, F.4    Weber, C.5    Pralle, H.6
  • 22
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9. (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 23
    • 0032757710 scopus 로고    scopus 로고
    • Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: Investigation of minimal residual disease in acute leukemia
    • van Dongen JJ, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia 1999;13:1901-28.
    • (1999) Leukemia , vol.13 , pp. 1901-1928
    • Van Dongen, J.J.1    Macintyre, E.A.2    Gabert, J.A.3    Delabesse, E.4    Rossi, V.5    Saglio, G.6
  • 24
    • 0030451722 scopus 로고    scopus 로고
    • Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
    • Nakao M, Yokota S, Iwai T, Kaneko H, Horiike S, Kashima K, http://www.ncbi.nlm.nih.gov/pubmed?term5%22Sonoda%20Y%22%5BAuthor%5D et al. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia 1996;10:1911-8.
    • (1996) Leukemia , vol.10 , pp. 1911-1918
    • Nakao, M.1    Yokota, S.2    Iwai, T.3    Kaneko, H.4    Horiike, S.5    Kashima, K.6
  • 25
    • 0742321800 scopus 로고    scopus 로고
    • Significant co-expression of WT1 and MDR1genes in acute myeloid leukemia patients at diagnosis
    • Galimberti S, Guerrini F, Carulli G, Fazzi R, Palumbo GA, Morabito F, et al. Significant co-expression of WT1 and MDR1genes in acute myeloid leukemia patients at diagnosis. Eur J Haematol 2004;72:45-51.
    • (2004) Eur J Haematol , vol.72 , pp. 45-51
    • Galimberti, S.1    Guerrini, F.2    Carulli, G.3    Fazzi, R.4    Palumbo, G.A.5    Morabito, F.6
  • 26
    • 0027205172 scopus 로고
    • Induction of DNA strand breaks associated with apoptosis during treatment of leukemias
    • Gorczyca W, Bigman K, Mittelman A, Ahmed T, Gong J, Melamed MR, et al. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia 1993;7:659-70.
    • (1993) Leukemia , vol.7 , pp. 659-670
    • Gorczyca, W.1    Bigman, K.2    Mittelman, A.3    Ahmed, T.4    Gong, J.5    Melamed, M.R.6
  • 27
    • 0027443378 scopus 로고
    • High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells
    • Bhalla K, Ibrado AM, Tourkina E, Tang C, Grant S, Bullock G, et al. High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells. Blood 1993;82:3133-40.
    • (1993) Blood , vol.82 , pp. 3133-3140
    • Bhalla, K.1    Ibrado, A.M.2    Tourkina, E.3    Tang, C.4    Grant, S.5    Bullock, G.6
  • 28
    • 0029069227 scopus 로고
    • Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias
    • Menssen HD, Renkl HJ, Rodeck U, Maurer J, Notter M, Schwartz S, et al. Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias. Leukemia 1995;9:1060-7.
    • (1995) Leukemia , vol.9 , pp. 1060-1067
    • Menssen, H.D.1    Renkl, H.J.2    Rodeck, U.3    Maurer, J.4    Notter, M.5    Schwartz, S.6
  • 29
    • 0030997045 scopus 로고    scopus 로고
    • Detection by monoclonal antibodies of the Wilms' tumor (WT1) nuclear protein in patients with acute leukemia
    • DOI 10.1002/(SICI)1097-0215(19970304)70:5<518::AID-IJC5>3.0.CO;2-0
    • Menssen HD, Renkl HJ, Rodeck U, Kari C, Schwartz S, Thiel E. Detection by monoclonal antibodies of the Wilms' tumor (WT1) nuclear protein in patients with acute leukemia. Int J Cancer 1997;70:518-23. (Pubitemid 27149634)
    • (1997) International Journal of Cancer , vol.70 , Issue.5 , pp. 518-523
    • Menssen, H.D.1    Renkl, H.-J.2    Rodeck, U.3    Kari, C.4    Schwartz, S.5    Thiel, E.6
  • 31
    • 0036796787 scopus 로고    scopus 로고
    • Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients
    • Cilloni D, Gottardi E, de Micheli D, Serra A, Volpe G, Messa F, et al. Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients. Leukemia 2002;16:2115-21.
    • (2002) Leukemia , vol.16 , pp. 2115-2121
    • Cilloni, D.1    Gottardi, E.2    De Micheli, D.3    Serra, A.4    Volpe, G.5    Messa, F.6
  • 32
    • 16944365952 scopus 로고    scopus 로고
    • Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia
    • Schmid D, HeinzeG, Linnerth B, Tisljar K, Kusec R, Geissler K, et al. Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia. Leukemia 1997;11:639-43.
    • (1997) Leukemia , vol.11 , pp. 639-643
    • Schmid, D.1    Heinze, G.2    Linnerth, B.3    Tisljar, K.4    Kusec, R.5    Geissler, K.6
  • 33
    • 0037114829 scopus 로고    scopus 로고
    • Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: A study of the AML study group Ulm
    • DOI 10.1182/blood-2002-05-1440
    • Frohling S, Schlenk RF, Breitruck J, Benner A, Kreitmeier S, Tobis K, et al. Prognostic significance of activating FLT3 mutations in younger adults (16-60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm. Blood 2002;100:4372-80. (Pubitemid 35434129)
    • (2002) Blood , vol.100 , Issue.13 , pp. 4372-4380
    • Frohling, S.1    Schlenk, R.F.2    Breitruck, J.3    Benner, A.4    Kreitmeier, S.5    Tobis, K.6    Dohner, H.7    Dohner, K.8
  • 34
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • Kottaridis PD, Gale RE, Frew ME, Harrison G, Langabeer SE, Belton AA, et al. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 2001;98:1752-9.
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3    Harrison, G.4    Langabeer, S.E.5    Belton, A.A.6
  • 35
    • 0035476264 scopus 로고    scopus 로고
    • Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
    • Whitman SP, Archer KJ, Feng L, Baldus C, Becknell B, Carlson BD, et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. Cancer Research 2001;61:7233-9.
    • (2001) Cancer Research , vol.61 , pp. 7233-7239
    • Whitman, S.P.1    Archer, K.J.2    Feng, L.3    Baldus, C.4    Becknell, B.5    Carlson, B.D.6
  • 36
    • 0032522974 scopus 로고    scopus 로고
    • Wilms' tumor (WT1) gene mutations occur mainly in acute myeloid leukemia and may confer drug resistance
    • King-Underwood L, Pritchard-Jones K. Wilms' tumor (WT1) gene mutations occur mainly in acute myeloid leukemia and may confer drug resistance. Blood 1998;91:2961-8.
    • (1998) Blood , vol.91 , pp. 2961-2968
    • King-Underwood, L.1    Pritchard-Jones, K.2


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