Genomic structure of human FLT3: Implications for mutational analysis [1]

British Journal of Haematology

Volumn 113, Issue 4, 2001, Pages 1076-1077

  Abu Duhier, F M ^a   Goodeve, A C ^a   Wilson, G A ^a   Care, R S ^a   Peake, I R ^a   Reilly, J T ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

FLT3; Gene; Genomic structure; Oncogene

Indexed keywords

PLATELET DERIVED GROWTH FACTOR RECEPTOR; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR; TYROSINE KINASE RECEPTOR;

DNA FLANKING REGION; EXON; GENE MUTATION; GENE SEQUENCE; GENE STRUCTURE; HUMAN; LETTER; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EXONS; FMS-LIKE TYROSINE KINASE 3; HUMANS; LEUKEMIA, MYELOID; MUTATION; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; REPETITIVE SEQUENCES, NUCLEIC ACID;

EID: 0034944794     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02821.x     Document Type: Letter

References (8)

1. FLT3 internal tandem duplication mutations in acute myeloid leukaemia (AML) define a poor risk group
2. Identification of novel FLT3 Asp835 mutations in adult acute myeloid leukaemia
3. Genomic structure of the downstream part of the human FLT3 gene: Exon/intron structure conservation among genes encoding receptor tyrosine kinases (RTK) of subclass III
4. Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells
5. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
6. Internal tandem duplication of the FLT3 gene found in acute myeloid leukemia
7. AML1 (-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 Gene