-
1
-
-
0029941043
-
The WT1 Wilms' tumor suppressor gene: How much do we really know?
-
Reddy JC, Licht JD: The WT1 Wilms' tumor suppressor gene: How much do we really know? Biochim Biophys Acta 1287:1, 1996
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 1
-
-
Reddy, J.C.1
Licht, J.D.2
-
2
-
-
0028587166
-
The genetics of Wilms' tumor - A case of disrupted development
-
Hastie ND: The genetics of Wilms' tumor - a case of disrupted development. Annu Rev Genet 28:523, 1994
-
(1994)
Annu Rev Genet
, vol.28
, pp. 523
-
-
Hastie, N.D.1
-
3
-
-
0025291908
-
The candidate Wilms' tumour gene is involved in genitourinary development
-
Pritchard-Jones K, Fleming S, Davidson D, Bickmore W, Porteous D, Gosden C, Bard J, Buckler A, Pelletier J, Housman D, van Heyningen V, Hastie N: The candidate Wilms' tumour gene is involved in genitourinary development. Nature 346:194, 1990
-
(1990)
Nature
, vol.346
, pp. 194
-
-
Pritchard-Jones, K.1
Fleming, S.2
Davidson, D.3
Bickmore, W.4
Porteous, D.5
Gosden, C.6
Bard, J.7
Buckler, A.8
Pelletier, J.9
Housman, D.10
Van Heyningen, V.11
Hastie, N.12
-
4
-
-
0031048878
-
Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia
-
Inoue K, Ogawa H, Sonoda Y, Kimura T, Sakabe H, Oka Y, Miyake S, Tamaki H, Oji Y, Yamagami T, Tatekawa T, Soma T, Kishimoto T, Sugiyama H: Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia. Blood 89:1405, 1997
-
(1997)
Blood
, vol.89
, pp. 1405
-
-
Inoue, K.1
Ogawa, H.2
Sonoda, Y.3
Kimura, T.4
Sakabe, H.5
Oka, Y.6
Miyake, S.7
Tamaki, H.8
Oji, Y.9
Yamagami, T.10
Tatekawa, T.11
Soma, T.12
Kishimoto, T.13
Sugiyama, H.14
-
6
-
-
0027182741
-
WT-1 is required for early kidney development
-
Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R: WT-1 is required for early kidney development. Cell 74:679, 1993
-
(1993)
Cell
, vol.74
, pp. 679
-
-
Kreidberg, J.A.1
Sariola, H.2
Loring, J.M.3
Maeda, M.4
Pelletier, J.5
Housman, D.6
Jaenisch, R.7
-
8
-
-
0029991989
-
A non-AUG translational initiation event generates novel WT1 isoforms
-
Bruening W, Pelletier J: A non-AUG translational initiation event generates novel WT1 isoforms. J Biol Chem 271:8646, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 8646
-
-
Bruening, W.1
Pelletier, J.2
-
9
-
-
0029839457
-
RNA binding by the Wilms tumor suppressor zinc finger proteins
-
Caricasole A, Duarte A, Larsson SH, Hastie ND, Little M, Holmes G, Todorov I, Ward A: RNA binding by the Wilms tumor suppressor zinc finger proteins. Proc Natl Acad Sci USA 93:7562, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7562
-
-
Caricasole, A.1
Duarte, A.2
Larsson, S.H.3
Hastie, N.D.4
Little, M.5
Holmes, G.6
Todorov, I.7
Ward, A.8
-
10
-
-
0029071508
-
Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing
-
Larsson SH, Charlieu JP, Miyagawa K, Engelkamp D, Rassoulzadegan M, Ross A, Cuzin F, van Heyningen V, Hastie ND: Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing. Cell 81:391, 1995
-
(1995)
Cell
, vol.81
, pp. 391
-
-
Larsson, S.H.1
Charlieu, J.P.2
Miyagawa, K.3
Engelkamp, D.4
Rassoulzadegan, M.5
Ross, A.6
Cuzin, F.7
Van Heyningen, V.8
Hastie, N.D.9
-
11
-
-
0027384536
-
Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus
-
Harrington MA, Konicek B, Song A, Xia XL, Fredericks WJ, Rauscher FJ III: Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus. J Biol Chem 268:21271, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 21271
-
-
Harrington, M.A.1
Konicek, B.2
Song, A.3
Xia, X.L.4
Fredericks, W.J.5
Rauscher III, F.J.6
-
12
-
-
2642648133
-
Two hematopoietic specific enhancers of the WT1 gene function in different cell lineages
-
Zhang X, Fraizer G, Saunders G: Two hematopoietic specific enhancers of the WT1 gene function in different cell lineages. Blood 86:748a, 1995 (abstr suppl 1)
-
(1995)
Blood
, vol.86
, Issue.1 ABSTR SUPPL.
-
-
Zhang, X.1
Fraizer, G.2
Saunders, G.3
-
13
-
-
0028206250
-
Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter
-
Fraizer GC, Wu YJ, Hewitt SM, Maity T, Ton CC, Huff V, Saunders GF: Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. J Biol Chem 269:8892, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 8892
-
-
Fraizer, G.C.1
Wu, Y.J.2
Hewitt, S.M.3
Maity, T.4
Ton, C.C.5
Huff, V.6
Saunders, G.F.7
-
15
-
-
0030891372
-
A clinical overview of WT1 gene mutations
-
Little M, Wells C: A clinical overview of WT1 gene mutations. Hum Mutat 9:209, 1997
-
(1997)
Hum Mutat
, vol.9
, pp. 209
-
-
Little, M.1
Wells, C.2
-
16
-
-
0028130136
-
WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia
-
Inoue K, Sugiyama H, Ogawa H, Nakagawa M, Yamagami T, Miwa H, Kita K, Hiraoka A, Masaoka T, Nasu K, Kyo T, Dohy H, Nakauchi H, Ishidate T, Akiyama T, Kishimoto T: WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 84:3071, 1994
-
(1994)
Blood
, vol.84
, pp. 3071
-
-
Inoue, K.1
Sugiyama, H.2
Ogawa, H.3
Nakagawa, M.4
Yamagami, T.5
Miwa, H.6
Kita, K.7
Hiraoka, A.8
Masaoka, T.9
Nasu, K.10
Kyo, T.11
Dohy, H.12
Nakauchi, H.13
Ishidate, T.14
Akiyama, T.15
Kishimoto, T.16
-
17
-
-
0028133507
-
The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient
-
Pritchard-Jones K, Renshaw J, King-Underwood L: The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient. Hum Mol Genet 3:1633, 1994
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1633
-
-
Pritchard-Jones, K.1
Renshaw, J.2
King-Underwood, L.3
-
18
-
-
0028979148
-
WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences
-
Huff V, Jaffe N, Saunders GF, Strong LC, Villalba F, Ruteshouser EC: WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences. Am J Hum Genet 56:84, 1995
-
(1995)
Am J Hum Genet
, vol.56
, pp. 84
-
-
Huff, V.1
Jaffe, N.2
Saunders, G.F.3
Strong, L.C.4
Villalba, F.5
Ruteshouser, E.C.6
-
19
-
-
0030951813
-
p53 abnormalities in B-cell prolymphocytic leukemia
-
Lens D, DeSchouwer PJJC, Hamoudi RA, AbdulRauf M, Farahat N, Matutes E, Crook T, Dyer MJS, Catovsky D: p53 abnormalities in B-cell prolymphocytic leukemia. Blood 89:2015, 1997
-
(1997)
Blood
, vol.89
, pp. 2015
-
-
Lens, D.1
DeSchouwer, P.J.J.C.2
Hamoudi, R.A.3
Abdulrauf, M.4
Farahat, N.5
Matutes, E.6
Crook, T.7
Dyer, M.J.S.8
Catovsky, D.9
-
20
-
-
33845382806
-
Non-parametric estimation from incomplete observations
-
Kaplan EL, Meier P: Non-parametric estimation from incomplete observations. J Am Stat Soc 53:457, 1958
-
(1958)
J Am Stat Soc
, vol.53
, pp. 457
-
-
Kaplan, E.L.1
Meier, P.2
-
21
-
-
0031042404
-
Mutation analysis of the WT1 gene in sporadic childhood leukaemia
-
Algar E, Blackburn D, Kromykh T, Taylor G, Smith P: Mutation analysis of the WT1 gene in sporadic childhood leukaemia. Leukemia 11:110, 1997
-
(1997)
Leukemia
, vol.11
, pp. 110
-
-
Algar, E.1
Blackburn, D.2
Kromykh, T.3
Taylor, G.4
Smith, P.5
-
22
-
-
0030851564
-
Dominant-negative mutations of the Wilms' tumour predisposing gene (WT1) are infrequent in CML blast crisis and de novo acute leukaemia
-
Carapeti M, Goldman JM, Cross NC: Dominant-negative mutations of the Wilms' tumour predisposing gene (WT1) are infrequent in CML blast crisis and de novo acute leukaemia. Eur J Haematol 58:346, 1997
-
(1997)
Eur J Haematol
, vol.58
, pp. 346
-
-
Carapeti, M.1
Goldman, J.M.2
Cross, N.C.3
-
23
-
-
0026704787
-
A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1 a in transformation of primary kidney cells
-
Haber DA, Timmers HT, Pelletier J, Sharp PA, Housman DE: A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1 A in transformation of primary kidney cells. Proc Natl Acad Sci USA 89:6010, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6010
-
-
Haber, D.A.1
Timmers, H.T.2
Pelletier, J.3
Sharp, P.A.4
Housman, D.E.5
-
24
-
-
0026724450
-
Zinc finger point mutations within the WT1 gene in Wilms tumor patients
-
Little MH, Prosser J, Condie A, Smith PJ, van Heyningen V, Hastie ND: Zinc finger point mutations within the WT1 gene in Wilms tumor patients. Proc Natl Acad Sci USA 89:4791, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4791
-
-
Little, M.H.1
Prosser, J.2
Condie, A.3
Smith, P.J.4
Van Heyningen, V.5
Hastie, N.D.6
-
25
-
-
0029832887
-
Effects of Denys-Drash syndrome point mutations on the DNA binding activity of the Wilms' tumor suppressor protein WT1
-
Borel F, Barilla KC, Hamilton TB, Iskandar M, Romaniuk PJ: Effects of Denys-Drash syndrome point mutations on the DNA binding activity of the Wilms' tumor suppressor protein WT1. Biochemistry 35:12070, 1996
-
(1996)
Biochemistry
, vol.35
, pp. 12070
-
-
Borel, F.1
Barilla, K.C.2
Hamilton, T.B.3
Iskandar, M.4
Romaniuk, P.J.5
-
26
-
-
0028926095
-
DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome point mutations
-
Little M, Holmes G, Bickmore W, van Heyningen V, Hastie N, Wainwright B: DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome point mutations. Hum Mol Genet 4:351, 1995
-
(1995)
Hum Mol Genet
, vol.4
, pp. 351
-
-
Little, M.1
Holmes, G.2
Bickmore, W.3
Van Heyningen, V.4
Hastie, N.5
Wainwright, B.6
-
27
-
-
0027328694
-
The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma
-
Park S, Schalling M, Bernard A, Maheswaran S, Shipley GC, Roberts D, Fletcher J, Shipman R, Rheinwald J, Demetri G, Griffin J, Minden M, Housman DE, Haber DA: The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma. Nat Genet 4:415, 1993
-
(1993)
Nat Genet
, vol.4
, pp. 415
-
-
Park, S.1
Schalling, M.2
Bernard, A.3
Maheswaran, S.4
Shipley, G.C.5
Roberts, D.6
Fletcher, J.7
Shipman, R.8
Rheinwald, J.9
Demetri, G.10
Griffin, J.11
Minden, M.12
Housman, D.E.13
Haber, D.A.14
-
28
-
-
0028792335
-
The evolution of WT1 sequence and expression pattern in the vertebrates
-
Kent J, Coriat AM, Sharpe PT, Hastie ND, van Heyningen V: The evolution of WT1 sequence and expression pattern in the vertebrates. Oncogene 11:1781, 1995
-
(1995)
Oncogene
, vol.11
, pp. 1781
-
-
Kent, J.1
Coriat, A.M.2
Sharpe, P.T.3
Hastie, N.D.4
Van Heyningen, V.5
-
29
-
-
0030579108
-
cDNA cloning and its pronephros-specific expression of the Wilms' tumor suppressor gene, WT1, from Xenopus laevis
-
Semba K, Saito Ueno R, Takayama G, Kondo M: cDNA cloning and its pronephros-specific expression of the Wilms' tumor suppressor gene, WT1, from Xenopus laevis. Gene 175:167, 1996
-
(1996)
Gene
, vol.175
, pp. 167
-
-
Semba, K.1
Saito Ueno, R.2
Takayama, G.3
Kondo, M.4
-
30
-
-
0028196679
-
Infrequent mutation of the WT1 gene in 77 Wilms' Tumors
-
Gessler M, Konig A, Arden K, Grundy P, Orkin S, Sallan S, Peters C, Ruyle S, Mandell J, Li F, Cavenee W, Bruns G: Infrequent mutation of the WT1 gene in 77 Wilms' Tumors. Hum Mutat 3:212, 1994
-
(1994)
Hum Mutat
, vol.3
, pp. 212
-
-
Gessler, M.1
Konig, A.2
Arden, K.3
Grundy, P.4
Orkin, S.5
Sallan, S.6
Peters, C.7
Ruyle, S.8
Mandell, J.9
Li, F.10
Cavenee, W.11
Bruns, G.12
-
31
-
-
0026470288
-
Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome
-
Baird PN, Groves N, Haber DA, Housman DE, Cowell JK: Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome. Oncogene 7:2141, 1992
-
(1992)
Oncogene
, vol.7
, pp. 2141
-
-
Baird, P.N.1
Groves, N.2
Haber, D.A.3
Housman, D.E.4
Cowell, J.K.5
-
32
-
-
0030889197
-
Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology
-
Schumacher V, Schneider S, Figge A, Wildhardt G, Harms D, Schmidt D, Weirich A, Ludwig R, Royer-Pokora B: Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology. Proc Natl Acad Sci USA 94:3972, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3972
-
-
Schumacher, V.1
Schneider, S.2
Figge, A.3
Wildhardt, G.4
Harms, D.5
Schmidt, D.6
Weirich, A.7
Ludwig, R.8
Royer-Pokora, B.9
-
33
-
-
0029616555
-
Truncated WT1 mutants alter the subnuclear localization of the wild-type protein
-
Englert C, Vidai M, Maheswaran S, Ge Y, Ezzell RM, Isselbacher KJ, Haber DA: Truncated WT1 mutants alter the subnuclear localization of the wild-type protein. Proc Natl Acad Sci USA 92:11960, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11960
-
-
Englert, C.1
Vidai, M.2
Maheswaran, S.3
Ge, Y.4
Ezzell, R.M.5
Isselbacher, K.J.6
Haber, D.A.7
-
34
-
-
0031589172
-
Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteins
-
Holmes G, Boterashvili S, English M, Wainwright B, Licht J, Little M: Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteins. Biochem Biophys Res Commun 233:723, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.233
, pp. 723
-
-
Holmes, G.1
Boterashvili, S.2
English, M.3
Wainwright, B.4
Licht, J.5
Little, M.6
-
35
-
-
0028985169
-
A critical mutation in both WT1 alleles is not sufficient to cause Wilms' tumor
-
Kikuchi H, Akasaka Y, Kurosawa Y, Yoneyama H, Kato S, Hata J: A critical mutation in both WT1 alleles is not sufficient to cause Wilms' tumor. FEBS Lett 360:26, 1995
-
(1995)
FEBS Lett
, vol.360
, pp. 26
-
-
Kikuchi, H.1
Akasaka, Y.2
Kurosawa, Y.3
Yoneyama, H.4
Kato, S.5
Hata, J.6
-
36
-
-
0024307919
-
Secondary leukemia following successful treatment of Wilms' tumor
-
Moss TJ, Strauss LC, Das L, Feig SA: Secondary leukemia following successful treatment of Wilms' tumor. Am J Pediatr Hematol Oncol 11:158, 1989
-
(1989)
Am J Pediatr Hematol Oncol
, vol.11
, pp. 158
-
-
Moss, T.J.1
Strauss, L.C.2
Das, L.3
Feig, S.A.4
-
37
-
-
0030789242
-
Human acute myeloid leukemia is organised as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE: Human acute myeloid leukemia is organised as a hierarchy that originates from a primitive hematopoietic cell. Nature Med 3:730, 1997
-
(1997)
Nature Med
, vol.3
, pp. 730
-
-
Bonnet, D.1
Dick, J.E.2
-
38
-
-
0029852374
-
Constitutive expression of the Wilms tumor suppressor gene WT1 in F9 embryonal carcinoma cells induces apototic cell death in response to retinoic acid
-
Kudoh T, Ishidate T, Nakamura T, Akiyama T: Constitutive expression of the Wilms tumor suppressor gene WT1 in F9 embryonal carcinoma cells induces apototic cell death in response to retinoic acid. Oncogene 13:1431, 1996
-
(1996)
Oncogene
, vol.13
, pp. 1431
-
-
Kudoh, T.1
Ishidate, T.2
Nakamura, T.3
Akiyama, T.4
-
39
-
-
0030955875
-
The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells
-
Murata Y, Kudoh T, Sugiyama H, Toyoshima K, Akiyama T: The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells. FEBS Lett 409:41, 1997
-
(1997)
FEBS Lett
, vol.409
, pp. 41
-
-
Murata, Y.1
Kudoh, T.2
Sugiyama, H.3
Toyoshima, K.4
Akiyama, T.5
-
40
-
-
0030978224
-
Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor
-
Menke AL, Shvarts A, Riteco N, van Ham RC, van der Eb AJ, Jochemsen AG: Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor. Cancer Res 57:1353, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 1353
-
-
Menke, A.L.1
Shvarts, A.2
Riteco, N.3
Van Ham, R.C.4
Van Der Eb, A.J.5
Jochemsen, A.G.6
-
41
-
-
9244237089
-
Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis
-
Yamagami T, Sugiyama H, Inoue K, Ogawa H, Tatekawa T, Hirata M, Kudoh T, Akiyama T, Murakami A, Maekawa T: Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis. Blood 87:2878, 1996
-
(1996)
Blood
, vol.87
, pp. 2878
-
-
Yamagami, T.1
Sugiyama, H.2
Inoue, K.3
Ogawa, H.4
Tatekawa, T.5
Hirata, M.6
Kudoh, T.7
Akiyama, T.8
Murakami, A.9
Maekawa, T.10
-
42
-
-
0029880547
-
A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines
-
Algar EM, Khromykh T, Smith SI, Blackburn DM, Bryson GJ, Smith PJ: A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines. Oncogene 12:1005, 1996
-
(1996)
Oncogene
, vol.12
, pp. 1005
-
-
Algar, E.M.1
Khromykh, T.2
Smith, S.I.3
Blackburn, D.M.4
Bryson, G.J.5
Smith, P.J.6
-
43
-
-
0029866180
-
Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation
-
Hewitt SM, Fraizer GC, Wu YJ, Rauscher FJ, 3rd, Saunders GF: Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation. J Biol Chem 271:8588, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 8588
-
-
Hewitt, S.M.1
Fraizer, G.C.2
Wu, Y.J.3
Rauscher III, F.J.4
Saunders, G.F.5
|