Cockayne syndrome B protects against methamphetamine-enhanced oxidative DNA damage in murine fetal brain and postnatal neurodevelopmental deficits

Antioxidants and Redox Signaling

Volumn 14, Issue 5, 2011, Pages 747-756

  McCallum, Gordon P ^a   Wong, Andrea W ^a   Wells, Peter G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; METHAMPHETAMINE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN PROTECTION; BRAIN TOXICITY; COCKAYNE SYNDROME; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DNA DAMAGE; ENZYME ACTIVITY; FEMALE; MOTOR COORDINATION; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SENSORIMOTOR NEUROPATHY;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; DNA DAMAGE; DNA REPAIR ENZYMES; FEMALE; GUANINE; LIVER; MALE; METHAMPHETAMINE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; OXIDATIVE STRESS; PREGNANCY;

MURINAE; MUS;

EID: 79551666065     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2009.2946     Document Type: Article

References (53)

1. Agrawal HC, Glisson SN, and Himwich WA. Developmental changes in monoamines of mouse brain. Int J Neuropharmacol 7: 97-101, 1968.
2. Alhava E. Amphetamine toxicity in adult and developing mice. Acta Pharmacol Toxicol (Copenh) 31: 387-400, 1972.
3. Bowyer JF. Neuronal degeneration in the limbic system of weanling rats exposed to saline, hyperthermia or damphetamine. Brain Res 885: 166-171, 2000.
4. Bowyer JF, Davies DL, Schmued L, Broening HW, Newport GD, Slikker W, Jr., and Holson RR. Further studies of the role of hyperthermia in methamphetamine neurotoxicity. J Pharmacol Exp Ther 268: 1571-1580, 1994.
5. Brooks PJ. DNA repair in neural cells: basic science and clinical implications. Mutat Res 509: 93-108, 2002.
6. Cadet JL and Brannock C. Free radicals and the pathobiology of brain dopamine systems. Neurochem Int 32: 117-131, 1998.
7. Cadet JL, Jayanthi S, and Deng X. Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis. FASEB J 17: 1775-1788, 2003.
8. Cadet JL, McCoy MT, and Ladenheim B. Distinct gene expression signatures in the striata of wild-type and heterozygous c-fos knockout mice following methamphetamine administration: evidence from cDNA array analyses. Synapse 44: 211-226, 2002.
9. Cappon GD, Morford LL, and Vorhees CV. Ontogeny of methamphetamine- induced neurotoxicity and associated hyperthermic response. Brain Res Dev Brain Res 103: 155-162, 1997.
10. Chang L, Smith LM, LoPresti C, Yonekura ML, Kuo J, Walot I, and Ernst T. Smaller subcortical volumes and cognitive deficits in children with prenatal methamphetamine exposure. Psychiatry Res 132: 95-106, 2004.
11. Charlet-Berguerand N, Feuerhahn S, Kong SE, Ziserman H, Conaway JW, Conaway R, and Egly JM. RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors. EMBO J 25: 5481-5491, 2006.
12. Citterio E, Van Den Boom V, Schnitzler G, Kanaar R, Bonte E, Kingston RE, Hoeijmakers JH, and Vermeulen W. ATPdependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor. Mol Cell Biol 20: 7643-7653, 2000.
13. de Waard H, de Wit J, andressoo JO, van Oostrom CT, Riis B, Weimann A, Poulsen HE, van Steeg H, Hoeijmakers JH, and van der Horst GT. Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage. Mol Cell Biol 24: 7941-7948, 2004.
14. de Waard H, de Wit J, Gorgels TG, van den Aardweg G, andressoo JO, Vermeij M, van Steeg H, Hoeijmakers JH, and van der Horst GT. Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice. DNA Repair (Amst) 2: 13-25, 2003.
15. Dianov G, Bischoff C, Sunesen M, and Bohr VA. Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells. Nucleic Acids Res 27: 1365-1368, 1999.
16. Englander EW and Ma H. Differential modulation of base excision repair activities during brain ontogeny: implications for repair of transcribed DNA. Mech Ageing Dev 127: 64-69, 2006.
17. Hailer-Morrison MK, Kotler JM, Martin BD, and Sugden KD. Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-20-deoxyguanosine lesions in the NFkappaB promoter element. Biochemistry 42: 9761-9770, 2003.
18. Hayashi M, Itoh M, Araki S, Kumada S, Shioda K, Tamagawa K, Mizutani T, Morimatsu Y, Minagawa M, and Oda M. Oxidative stress and disturbed glutamate transport in hereditary nucleotide repair disorders. J Neuropathol Exp Neurol 60: 350-356, 2001.
19. Hu J, de Souza-Pinto NC, Haraguchi K, Hogue BA, Jaruga P, Greenberg MM, Dizdaroglu M, and Bohr VA. Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem 280: 40544-40551, 2005.
20. Itoh M, Hayashi M, Shioda K, Minagawa M, Isa F, Tamagawa K, Morimatsu Y, and Oda M. Neurodegeneration in hereditary nucleotide repair disorders. Brain Dev 21: 326-333, 1999.
21. Jeng W, Ramkissoon A, Parman T, and Wells PG. Prostaglandin H synthase-catalyzed bioactivation of amphetamines to free radical intermediates that cause CNS regional DNA oxidation and nerve terminal degeneration. FASEB J 20: 638-650, 2006.
22. Jeng W, Wong AW, Ting AKR, and Wells PG. Methamphetamine-enhanced embryonic oxidative DNA damage and neurodevelopmental deficits. Free Radic Biol Med 39: 317-326, 2005.
23. Kirkali G, de Souza-Pinto NC, Jaruga P, Bohr VA, and Dizdaroglu M. Accumulation of (50S)-8,50-cyclo-20-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice. DNA Repair (Amst) 8: 274-278, 2009.
24. Klungland A, Rosewell I, Hollenbach S, Larsen E, Daly G, Epe B, Seeberg E, Lindahl T, and Barnes DE. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci U S A 96: 13300-13305, 1999.
25. Kohji T, Hayashi M, Shioda K, Minagawa M, Morimatsu Y, Tamagawa K, and Oda M. Cerebellar neurodegeneration in human hereditary DNA repair disorders. Neurosci Lett 243: 133-136, 1998.
26. Kyng KJ, May A, Brosh RM, Jr., Cheng WH, Chen C, Becker KG, and Bohr VA. The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells. Oncogene 22: 1135-1149, 2003.
27. Lee KA, Bindereif A, and Green MR. A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing. Gene Analysis Tech 5: 22-31, 1988.
28. Licht CL, Stevnsner T, and Bohr VA. Cockayne syndrome group B cellular and biochemical functions. Am J Hum Genet 73: 1217-1239, 2003.
29. Liu L and Wells PG. DNA oxidation as a potential molecular mechanism mediating drug-induced birth defects: phenytoin and structurally related teratogens initiate the formation of 8-hydroxy-20-deoxyguanosine in vitro and in vivo in murine maternal hepatic and embryonic tissues. Free Radic Biol Med 19: 639-648, 1995.
30. Maddukuri L, Speina E, Christiansen M, Dudzinska D, Zaim J, Obtulowicz T, Kabaczyk S, Komisarski M, Bukowy Z, Szczegielniak J, Wojcik A, Kusmierek JT, Stevnsner T, Bohr VA, and Tudek B. Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2- nonenal. Mutat Res 666: 23-31, 2009.
31. Martin SM, Malkinson TJ, Veale WL, and Pittman QJ. Fever in pregnant, parturient, and lactating rats. Am J Physiol 268: R919-R923, 1995.
32. Nance MA and Berry SA. Cockayne syndrome: review of 140 cases. Am J Med Genet 42: 68-84, 1992.
33. Newman JC, Bailey AD, and Weiner AM. Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling. Proc Natl Acad Sci U S A 103: 9613-9618, 2006.
34. Osterod M, Larsen E, Le Page F, Hengstler JG, Van Der Horst GT, Boiteux S, Klungland A, and Epe B. A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. Oncogene 21: 8232-8239, 2002.
35. Pastoriza-Gallego M, Armier J, and Sarasin A. Transcription through 8-oxoguanine in DNA repair-proficient and Csb(-)=Ogg1(-) DNA repair-deficient mouse embryonic fibroblasts is dependent upon promoter strength and sequence context. Mutagenesis 22: 343-351, 2007.
36. Paz-Elizur T, Elinger D, Leitner-Dagan Y, Blumenstein S, Krupsky M, Berrebi A, Schechtman E, and Livneh Z. Development of an enzymatic DNA repair assay for molecular epidemiology studies: distribution of OGG activity in healthy individuals. DNA Repair (Amst) 6: 45-60, 2007.
37. Perillo B, Ombra MN, Bertoni A, Cuozzo C, Sacchetti S, Sasso A, Chiariotti L, Malorni A, Abbondanza C, and Avvedimento EV. DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression. Science 319: 202-206, 2008.
38. Plessinger MA. Prenatal exposure to amphetamines. Risks and adverse outcomes in pregnancy. Obstet Gynecol Clin North Am 25: 119-138, 1998.
39. Pu C and Vorhees CV. Developmental dissociation of methamphetamine- induced depletion of dopaminergic terminals and astrocyte reaction in rat striatum. Brain Res Dev Brain Res 72: 325-328, 1993.
40. Shibutani S and Grollman AP. Miscoding during DNA synthesis on damaged DNA templates catalysed by mammalian cell extracts. Cancer Lett 83: 315-322, 1994.
41. Spencer SJ, Mouihate A, Galic MA, and Pittman QJ. Central and peripheral neuroimmune responses: hyporesponsiveness during pregnancy. J Physiol 586: 399-406, 2008.
42. Spivak G and Hanawalt PC. Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts. DNA Repair (Amst) 5: 13-22, 2006.
43. Thorslund T, von Kobbe C, Harrigan JA, Indig FE, Christiansen M, Stevnsner T, and Bohr VA. Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress. Mol Cell Biol 25: 7625-7636, 2005.
44. Tuo J, Chen C, Zeng X, Christiansen M, and Bohr VA. Functional crosstalk between hOgg1 and the helicase domain of Cockayne syndrome group B protein. DNA Repair (Amst) 1: 913-927, 2002.
45. Tuo J, Jaruga P, Rodriguez H, Bohr VA, and Dizdaroglu M. Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress. FASEB J 17: 668-674, 2003.
46. Tuo J, Muftuoglu M, Chen C, Jaruga P, Selzer RR, Brosh RM, Jr., Rodriguez H, Dizdaroglu M, and Bohr VA. The Cockayne syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA. J Biol Chem 276: 45772-45779, 2001.
47. van der Horst GT, van Steeg H, Berg RJ, van Gool AJ, de Wit J, Weeda G, Morreau H, Beems RB, van Kreijl CF, de Gruijl FR, Bootsma D, and Hoeijmakers JH. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 89: 425-435, 1997.
48. Venema J, Mullenders LH, Natarajan AT, van Zeeland AA, and Mayne LV. The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc Natl Acad Sci U S A 87: 4707-4711, 1990.
49. Viswanathan A and Doetsch PW. Effects of nonbulky DNA base damages on Escherichia coli RNA polymerase-mediated elongation and promoter clearance. J Biol Chem 273: 21276-21281, 1998.
50. Wells PG, Kim PM, Laposa RR, Nicol CJ, Parman T, and Winn LM. Oxidative damage in chemical teratogenesis. Mutat Res 396: 65-78, 1997.
51. Winn LM and Wells PG. Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis. Free Radic Biol Med 22: 607-621, 1997.
52. Wong AW, McCallum GP, Jeng W, and Wells PG. Oxoguanine glycosylase 1 protects against methamphetamineenhanced fetal brain oxidative DNA damage and neurodevelopmental deficits. J Neurosci 28: 9047-9054, 2008.
53. Zharkov DO, Rosenquist TA, Gerchman SE, and Grollman AP. Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase. J Biol Chem 275: 28607-28617, 2000.