-
1
-
-
0029978844
-
Macrophage killing is an essential virulence mechanism of Salmonella typhimurium
-
Lindgren, S. W., Stojiljkovic, I., and Heffron, F. (1996) Macrophage killing is an essential virulence mechanism of Salmonella typhimurium. Proc. Natl. Acad. Sci. U. S. A. 93, 4197-4201
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 4197-4201
-
-
Lindgren, S.W.1
Stojiljkovic, I.2
Heffron, F.3
-
2
-
-
0035057454
-
Diverse virulence traits underlying different clinical outcomes of Salmonella infection
-
Fierer, J., and Guiney, D. G. (2001) Diverse virulence traits underlying different clinical outcomes of Salmonella infection. J. Clin. Invest. 107, 775-780
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 775-780
-
-
Fierer, J.1
Guiney, D.G.2
-
3
-
-
0011736531
-
Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
-
Fields, P. I., Swanson, R. V., Haidaris, C. G., and Heffron, F. (1986) Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad. Sci. U. S. A. 83, 5189-5193
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 5189-5193
-
-
Fields, P.I.1
Swanson, R.V.2
Haidaris, C.G.3
Heffron, F.4
-
4
-
-
0032560467
-
The crucial role of polymorphonuclear leukocytes in resistance to Salmonella dublin infections in genetically susceptible and resistant mice
-
Vassiloyanakopoulos, A. P., Okamoto, S., and Fierer, J. (1998) The crucial role of polymorphonuclear leukocytes in resistance to Salmonella dublin infections in genetically susceptible and resistant mice. Proc. Natl. Acad. Sci. U. S. A. 95, 7676-7681
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 7676-7681
-
-
Vassiloyanakopoulos, A.P.1
Okamoto, S.2
Fierer, J.3
-
5
-
-
33845192483
-
Salmonella typhimurium disseminates within its host by manipulating the motility of infected cells
-
Worley, M. J., Nieman, G. S., Geddes, K., and Heffron, F. (2006) Salmonella typhimurium disseminates within its host by manipulating the motility of infected cells. Proc. Natl. Acad. Sci. U. S. A. 103, 17915-17920
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 17915-17920
-
-
Worley, M.J.1
Nieman, G.S.2
Geddes, K.3
Heffron, F.4
-
6
-
-
0026670848
-
Salmonella typhimurium bacteremia: Association with the virulence plasmid
-
Fierer, J., Krause, M., Tauxe, R., and Guiney, D. (1992) Salmonella typhimurium bacteremia: association with the virulence plasmid. J. Infect. Dis. 166, 639-642
-
(1992)
J. Infect. Dis.
, vol.166
, pp. 639-642
-
-
Fierer, J.1
Krause, M.2
Tauxe, R.3
Guiney, D.4
-
7
-
-
0033999369
-
The Salmonella virulence plasmid spv genes are required for cytopathology in human monocyte-derived macrophages
-
Libby, S. J., Lesnick, M., Hasegawa, P., Weidenhamme, R. E., and Guiney, D. G. (2000) The Salmonella virulence plasmid spv genes are required for cytopathology in human monocyte-derived macrophages. Cell Micro. 2, 49-58
-
(2000)
Cell Micro.
, vol.2
, pp. 49-58
-
-
Libby, S.J.1
Lesnick, M.2
Hasegawa, P.3
Weidenhamme, R.E.4
Guiney, D.G.5
-
8
-
-
0034932788
-
Virulence plasmid-borne spvB and spvC genes can replace the 90-kilobase plasmid in conferring virulence to Salmonella enterica serovar Typhimurium in subcutaneously inoculated mice
-
Matsui, H., Bacot, C. M., Garlington, W. A., Doyle, T. J., Roberts, S., and Gulig, P. A. (2001) Virulence plasmid-borne spvB and spvC genes can replace the 90-kilobase plasmid in conferring virulence to Salmonella enterica serovar Typhimurium in subcutaneously inoculated mice. J. Bacteriol. 183, 4652-4658
-
(2001)
J. Bacteriol.
, vol.183
, pp. 4652-4658
-
-
Matsui, H.1
Bacot, C.M.2
Garlington, W.A.3
Doyle, T.J.4
Roberts, S.5
Gulig, P.A.6
-
9
-
-
0036893660
-
Genetic requirements for Salmonella-induced cytopathology in human monocyte-derived macrophages
-
Browne, S. H., Lesnick, M. L., and Guiney, D. G. (2002) Genetic requirements for Salmonella-induced cytopathology in human monocyte-derived macrophages. Infect. Immun. 70, 7126-7135
-
(2002)
Infect. Immun.
, vol.70
, pp. 7126-7135
-
-
Browne, S.H.1
Lesnick, M.L.2
Guiney, D.G.3
-
10
-
-
0035064654
-
The Salmonella spvB virulence gene encodes an enzyme that ADP-ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells
-
Lesnick, M. L., Reiner, N. E., Fierer, J., and Guiney, D. G. (2001) The Salmonella spvB virulence gene encodes an enzyme that ADP-ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells. Mol. Microbiol. 39, 1464-1470
-
(2001)
Mol. Microbiol.
, vol.39
, pp. 1464-1470
-
-
Lesnick, M.L.1
Reiner, N.E.2
Fierer, J.3
Guiney, D.G.4
-
11
-
-
0033812602
-
The spvB gene-product of the Salmonella enterica virulence plasmid is a mono(ADP-ribosyl) transferase
-
Otto, H., Tezcan-Merdol, D., Girisch, R., Haag, F., Rhen, M., and Koch-Nolte, F. (2000) The spvB gene-product of the Salmonella enterica virulence plasmid is a mono(ADP-ribosyl) transferase. Mol. Microbiol. 37, 1106-1115
-
(2000)
Mol. Microbiol.
, vol.37
, pp. 1106-1115
-
-
Otto, H.1
Tezcan-Merdol, D.2
Girisch, R.3
Haag, F.4
Rhen, M.5
Koch-Nolte, F.6
-
12
-
-
0035131629
-
Actin is ADP-ribosylated by the Salmonella enterica virulence-associated protein SpvB
-
Tezcan-Merdol, D., Nyman, T., Lindberg, U., Haag, F., Koch- Nolte, F., and Rhen, M. (2001) Actin is ADP-ribosylated by the Salmonella enterica virulence-associated protein SpvB. Mol. Microbiol. 39, 606-619
-
(2001)
Mol. Microbiol.
, vol.39
, pp. 606-619
-
-
Tezcan-Merdol, D.1
Nyman, T.2
Lindberg, U.3
Haag, F.4
Koch-Nolte, F.5
Rhen, M.6
-
13
-
-
39049167108
-
Identification of Salmonella SPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice
-
Browne, S. H., Hasegawa, P., Okamoto, S., Fierer, J., and Guiney, D. G. (2008) Identification of Salmonella SPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice. FEMS Immunol. Med. Microbiol. 52, 194-201
-
(2008)
FEMS Immunol. Med. Microbiol.
, vol.52
, pp. 194-201
-
-
Browne, S.H.1
Hasegawa, P.2
Okamoto, S.3
Fierer, J.4
Guiney, D.G.5
-
14
-
-
33746855102
-
A steric antagonism of actin polymerization by a Salmonella virulence protein
-
Margarit, S. M., Davidson, W., Frego, L., and Stebbins, C. E. (2006) A steric antagonism of actin polymerization by a Salmonella virulence protein. Structure 14, 1219-1229
-
(2006)
Structure
, vol.14
, pp. 1219-1229
-
-
Margarit, S.M.1
Davidson, W.2
Frego, L.3
Stebbins, C.E.4
-
15
-
-
0038690245
-
Intracellular expression of the Salmonella plasmid virulence protein, SpvB, causes apoptotic cell death in eukaryotic cells
-
Kurita, A., Gotoh, H., Eguchi, M., Okada, N., Matsuura, S., Matsui, H., Danbara, H., and Kikuchi, Y. (2003) Intracellular expression of the Salmonella plasmid virulence protein, SpvB, causes apoptotic cell death in eukaryotic cells. Microb. Pathog. 35, 43-48
-
(2003)
Microb. Pathog.
, vol.35
, pp. 43-48
-
-
Kurita, A.1
Gotoh, H.2
Eguchi, M.3
Okada, N.4
Matsuura, S.5
Matsui, H.6
Danbara, H.7
Kikuchi, Y.8
-
16
-
-
52049115828
-
Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases
-
Koch-Nolte, F., Kernstock, S., Mueller-Dieckmann, C., Weiss, M. S., and Haag, F. (2008) Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases. Front. Biosci. 13, 6716-6729
-
(2008)
Front. Biosci.
, vol.13
, pp. 6716-6729
-
-
Koch-Nolte, F.1
Kernstock, S.2
Mueller-Dieckmann, C.3
Weiss, M.S.4
Haag, F.5
-
17
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
Hamers-Casterman, C., Atarhouch, T., Muyldermans, S., Robinson, G., Hamers, C., Songa, E. B., Bendahman, N., and Hamers, R. (1993) Naturally occurring antibodies devoid of light chains. Nature 363, 446-448
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
Hamers-Casterman, C.1
Atarhouch, T.2
Muyldermans, S.3
Robinson, G.4
Hamers, C.5
Songa, E.B.6
Bendahman, N.7
Hamers, R.8
-
18
-
-
0035312546
-
Recognition of antigens by single-domain antibody fragments: The superfluous luxury of paired domains
-
Muyldermans, S., Cambillau, C., and Wyns, L. (2001) Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains. Trends Biochem. Sci. 26, 230-235
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 230-235
-
-
Muyldermans, S.1
Cambillau, C.2
Wyns, L.3
-
19
-
-
35348819390
-
Properties, production, and applications of camelid single-domain antibody fragments
-
Harmsen, M. M., and De Haard, H. J. (2007) Properties, production, and applications of camelid single-domain antibody fragments. Appl. Microbiol. Biotechnol. 77, 13-22
-
(2007)
Appl. Microbiol. Biotechnol.
, vol.77
, pp. 13-22
-
-
Harmsen, M.M.1
De Haard, H.J.2
-
20
-
-
68349117269
-
Single domain antibodies: Promising experimental and therapeutic tools in infection and immunity
-
Wesolowski, J., Alzogaray, V., Reyelt, J., Unger, M., Juarez, K., Urrutia, M., Cauerhff, A., Danquah, W., Rissiek, B., Scheuplein, F., Schwarz, N., Adriouch, S., Boyer, O., Seman, M., Licea, A., Serreze, D. V., Goldbaum, F. A., Haag, F., and Koch-Nolte, F. (2009) Single domain antibodies: promising experimental and therapeutic tools in infection and immunity. Med. Microbiol. Immunol. 198, 157-174
-
(2009)
Med. Microbiol. Immunol.
, vol.198
, pp. 157-174
-
-
Wesolowski, J.1
Alzogaray, V.2
Reyelt, J.3
Unger, M.4
Juarez, K.5
Urrutia, M.6
Cauerhff, A.7
Danquah, W.8
Rissiek, B.9
Scheuplein, F.10
Schwarz, N.11
Adriouch, S.12
Boyer, O.13
Seman, M.14
Licea, A.15
Serreze, D.V.16
Goldbaum, F.A.17
Haag, F.18
Koch-Nolte, F.19
-
21
-
-
0035831483
-
Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs
-
Conrath, E. K., Lauwereys, M., Wyns, L., and Muyldermans, S. (2001) Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs. J. Biol. Chem. 276, 7346-7350
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7346-7350
-
-
Conrath, E.K.1
Lauwereys, M.2
Wyns, L.3
Muyldermans, S.4
-
22
-
-
0036182644
-
Single-domain antibody fragments with high conformational stability
-
Dumoulin, M., Conrath, K., Van Meirhaeghe, A., Meersman, F., Heremans, K., Frenken, L. G., Muyldermans, S., Wyns, L., and Matagne, A. (2002) Single-domain antibody fragments with high conformational stability. Protein Sci. 11, 500-515
-
(2002)
Protein Sci.
, vol.11
, pp. 500-515
-
-
Dumoulin, M.1
Conrath, K.2
Van Meirhaeghe, A.3
Meersman, F.4
Heremans, K.5
Frenken, L.G.6
Muyldermans, S.7
Wyns, L.8
Matagne, A.9
-
23
-
-
33845922737
-
Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR nanobodies
-
Roovers, R., Laeremans, T., Huang, L., De Taeye, S., Verkleij, A., Revets, H., de Haard, H. J., and van Bergen en Henegouwen, P. M. (2007) Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR nanobodies. Cancer Immunol Immunother 56, 303-317
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 303-317
-
-
Roovers, R.1
Laeremans, T.2
Huang, L.3
De Taeye, S.4
Verkleij, A.5
Revets, H.6
De Haard, H.J.7
Van Bergen En Henegouwen, P.M.8
-
24
-
-
53349171633
-
Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: Taking advantage of modular nanobody technology
-
Tijink, B. M., Laeremans, T., Budde, M., Stigter-van Walsum, M., Dreier, T., de Haard, H. J., Leemans, C. R., and van Dongen, G. A. (2008) Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular nanobody technology. Mol. Cancer Ther. 7, 2288-2297
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2288-2297
-
-
Tijink, B.M.1
Laeremans, T.2
Budde, M.3
Stigter-van Walsum, M.4
Dreier, T.5
De Haard, H.J.6
Leemans, C.R.7
Van Dongen, G.A.8
-
25
-
-
0029764444
-
Crystal structure of a camel single-domain VH anti-body fragment in complex with lysozyme
-
Desmyter, A., Transue, T. R., Ghahroudi, M. A., Thi, M. H., Poortmans, F., Hamers, R., Muyldermans, S., and Wyns, L. (1996) Crystal structure of a camel single-domain VH anti-body fragment in complex with lysozyme. Nat. Struct. Biol. 3, 803-811
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 803-811
-
-
Desmyter, A.1
Transue, T.R.2
Ghahroudi, M.A.3
Thi, M.H.4
Poortmans, F.5
Hamers, R.6
Muyldermans, S.7
Wyns, L.8
-
26
-
-
33645241975
-
Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies
-
De Genst, E., Silence, K., Decanniere, K., Conrath, K., Loris, R., Kinne, J., Muyldermans, S., and Wyns, L. (2006) Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc. Natl. Acad. Sci. U. S. A. 103, 4586-4591
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4586-4591
-
-
De Genst, E.1
Silence, K.2
Decanniere, K.3
Conrath, K.4
Loris, R.5
Kinne, J.6
Muyldermans, S.7
Wyns, L.8
-
27
-
-
0344447084
-
Potent enzyme inhibitors derived from dromedary heavy-chain antibodies
-
Lauwereys, M., Arbabi Ghahroudi, M., Desmyter, A., Kinne, J., Hölzer, W., De Genst, E., Wyns, L., and Muyldermans, S. (1998) Potent enzyme inhibitors derived from dromedary heavy-chain antibodies. EMBO J. 17, 3512-3520
-
(1998)
EMBO J.
, vol.17
, pp. 3512-3520
-
-
Lauwereys, M.1
Arbabi Ghahroudi, M.2
Desmyter, A.3
Kinne, J.4
Hölzer, W.5
De Genst, E.6
Wyns, L.7
Muyldermans, S.8
-
28
-
-
60849118639
-
Camelid immunoglobulins and nanobody technology
-
Muyldermans, S., Baral, T. N., Retamozzo, V. C., De Baetselier, P., De Genst, E., Kinne, J., Leonhardt, H., Magez, S., Nguyen, V. K., Revets, H., Rothbauer, U., Stijlemans, B., Tillib, S., Wernery, U., Wyns, L., Hassanzadeh-Ghassabeh, G., and Saerens, D. (2009) Camelid immunoglobulins and nanobody technology. Vet. Immunol. Immunopathol. 128, 178-183
-
(2009)
Vet. Immunol. Immunopathol.
, vol.128
, pp. 178-183
-
-
Muyldermans, S.1
Baral, T.N.2
Retamozzo, V.C.3
De Baetselier, P.4
De Genst, E.5
Kinne, J.6
Leonhardt, H.7
Magez, S.8
Nguyen, V.K.9
Revets, H.10
Rothbauer, U.11
Stijlemans, B.12
Tillib, S.13
Wernery, U.14
Wyns, L.15
Hassanzadeh-Ghassabeh, G.16
Saerens, D.17
-
29
-
-
10644228142
-
Efficient cancer therapy with a nanobody-based conjugate
-
Cortez-Retamozo, V., Backmann, N., Senter, P. D., Wernery, U., De Baetselier, P., Muyldermans, S., and Revets, H. (2004) Efficient cancer therapy with a nanobody-based conjugate. Cancer Res. 64, 2853-2857
-
(2004)
Cancer Res.
, vol.64
, pp. 2853-2857
-
-
Cortez-Retamozo, V.1
Backmann, N.2
Senter, P.D.3
Wernery, U.4
De Baetselier, P.5
Muyldermans, S.6
Revets, H.7
-
30
-
-
33646545070
-
Experimental therapy of African trypanosomiasis with a nano-body- conjugated human trypanolytic factor
-
Baral, T. N., Magez, S., Stijlemans, B., Conrath, K., Vanhollebeke, B., Pays, E., Muyldermans, S., and De Baetselier, P. (2006) Experimental therapy of African trypanosomiasis with a nano-body- conjugated human trypanolytic factor. Nat. Med. 12, 580-584
-
(2006)
Nat. Med.
, vol.12
, pp. 580-584
-
-
Baral, T.N.1
Magez, S.2
Stijlemans, B.3
Conrath, K.4
Vanhollebeke, B.5
Pays, E.6
Muyldermans, S.7
De Baetselier, P.8
-
31
-
-
33745032737
-
Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis
-
Coppieters, K., Dreier, T., Silence, K., De Haard, H., Lauwereys, M., Casteels, P., Beirnaert, E., Jonckheere, H., Van de Wiele, C., Staelens, L., Hostens, J., Revets, H., Remaut, E., Elewaut, D., and Rottiers, P. (2006) Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis. Arthritis Rheum. 54, 1856-1866
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 1856-1866
-
-
Coppieters, K.1
Dreier, T.2
Silence, K.3
De Haard, H.4
Lauwereys, M.5
Casteels, P.6
Beirnaert, E.7
Jonckheere, H.8
Van De Wiele, C.9
Staelens, L.10
Hostens, J.11
Revets, H.12
Remaut, E.13
Elewaut, D.14
Rottiers, P.15
-
32
-
-
35948991091
-
Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo
-
Koch-Nolte, F., Reyelt, J., Schössow, B., Schwarz, N., Scheuplein, F., Rothenburg, S., Haag, F., Alzogaray, V., Cauerhff, A., and Goldbaum, F. A. (2007) Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo. FASEB J. 21, 3490-3498
-
(2007)
FASEB J.
, vol.21
, pp. 3490-3498
-
-
Koch-Nolte, F.1
Reyelt, J.2
Schössow, B.3
Schwarz, N.4
Scheuplein, F.5
Rothenburg, S.6
Haag, F.7
Alzogaray, V.8
Cauerhff, A.9
Goldbaum, F.A.10
-
33
-
-
0042467574
-
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme
-
Dumoulin, M., Last, A. M., Desmyter, A., Decanniere, K., Canet, D., Larsson, G., Spencer, A., Archer, D. B., Sasse, J., Muyldermans, S., Wyns, L., Redfield, C., Matagne, A., Robinson, C. V., and Dobson, C. M. (2003) A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme. Nature 424, 783-788
-
(2003)
Nature
, vol.424
, pp. 783-788
-
-
Dumoulin, M.1
Last, A.M.2
Desmyter, A.3
Decanniere, K.4
Canet, D.5
Larsson, G.6
Spencer, A.7
Archer, D.B.8
Sasse, J.9
Muyldermans, S.10
Wyns, L.11
Redfield, C.12
Matagne, A.13
Robinson, C.V.14
Dobson, C.M.15
-
34
-
-
37649019187
-
Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils
-
Habicht, G., Haupt, C., Friedrich, R. P., Hortschansky, P., Sachse, C., Meinhardt, J., Wieligmann, K., Gellermann, G. P., Brodhun, M., Götz, J., Halbhuber, K. J., Röcken, C., Horn, U., and Fändrich, M. (2007) Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils. Proc. Natl. Acad. Sci. U. S. A. 104, 19232-19237
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 19232-19237
-
-
Habicht, G.1
Haupt, C.2
Friedrich, R.P.3
Hortschansky, P.4
Sachse, C.5
Meinhardt, J.6
Wieligmann, K.7
Gellermann, G.P.8
Brodhun, M.9
Götz, J.10
Halbhuber, K.J.11
Röcken, C.12
Horn, U.13
Fändrich, M.14
-
35
-
-
33750328972
-
Targeting and tracing antigens in live cells with fluorescent nanobodies
-
Rothbauer, U., Zolghadr, K., Tillib, S., Nowak, D., Schermelleh, L., Gahl, A., Backmann, N., Conrath, K., Muyldermans, S., Cardoso, M. C., and Leonhardt, H. (2006) Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat. Methods 3, 887-889
-
(2006)
Nat. Methods
, vol.3
, pp. 887-889
-
-
Rothbauer, U.1
Zolghadr, K.2
Tillib, S.3
Nowak, D.4
Schermelleh, L.5
Gahl, A.6
Backmann, N.7
Conrath, K.8
Muyldermans, S.9
Cardoso, M.C.10
Leonhardt, H.11
-
36
-
-
33845673605
-
Identification of single-domain, Bax-specific intrabodies that confer resistance to mammalian cells against oxidative-stress-induced apoptosis
-
Gueorguieva, D., Li, S., Walsh, N., Mukerji, A., Tanha, J., and Pandey, S. (2006) Identification of single-domain, Bax-specific intrabodies that confer resistance to mammalian cells against oxidative-stress-induced apoptosis. FASEB J. 20, 2636-2638
-
(2006)
FASEB J.
, vol.20
, pp. 2636-2638
-
-
Gueorguieva, D.1
Li, S.2
Walsh, N.3
Mukerji, A.4
Tanha, J.5
Pandey, S.6
-
37
-
-
65449169579
-
Prevention of oculopharyngeal muscular dystrophy by muscular expression of Llama single-chain intrabodies in vivo
-
Chartier, A., Raz, V., Sterrenburg, E., Verrips, C. T., van der Maarel, S. M., and Simonelig, M. (2009) Prevention of oculopharyngeal muscular dystrophy by muscular expression of Llama single-chain intrabodies in vivo. Hum. Mol. Genet. 18, 1849-1859
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1849-1859
-
-
Chartier, A.1
Raz, V.2
Sterrenburg, E.3
Verrips, C.T.4
Van Der Maarel, S.M.5
Simonelig, M.6
-
38
-
-
28044459831
-
Human single-domain neutralizing intrabodies directed against Etk kinase: A novel approach to impair cellular transformation
-
Paz, K., Brennan, L. A., Iacolina, M., Doody, J., Hadari, Y. R., and Zhu, Z. (2005) Human single-domain neutralizing intrabodies directed against Etk kinase: a novel approach to impair cellular transformation. Mol. Cancer Ther. 4, 1801-1809
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1801-1809
-
-
Paz, K.1
Brennan, L.A.2
Iacolina, M.3
Doody, J.4
Hadari, Y.R.5
Zhu, Z.6
-
39
-
-
20444391361
-
Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo
-
Jendreyko, N., Popkov, M., Rader, C., and Barbas, C. F., 3rd (2005) Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo. Proc. Natl. Acad. Sci. U. S. A. 102, 8293-8298
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 8293-8298
-
-
Jendreyko, N.1
Popkov, M.2
Rader, C.3
Barbas III, C.F.4
-
40
-
-
38449115445
-
Intracellular antibodies (intrabodies) and their therapeutic potential
-
Lo, A. S., Zhu, Q., and Marasco, W. A. (2008) Intracellular antibodies (intrabodies) and their therapeutic potential. Handb. Exp. Pharmacol. 343-373
-
(2008)
Handb. Exp. Pharmacol.
, pp. 343-373
-
-
Lo, A.S.1
Zhu, Q.2
Marasco, W.A.3
-
41
-
-
2942724405
-
Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity
-
Aires da Silva, F., Santa-Marta, M., Freitas-Vieira, A., Mascarenhas, P., Barahona, I., Moniz-Pereira, J., Gabuzda, D., and Goncalves, J. (2004) Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity. J. Mol. Biol. 340, 525-542
-
(2004)
J. Mol. Biol.
, vol.340
, pp. 525-542
-
-
Aires Da Silva, F.1
Santa-Marta, M.2
Freitas-Vieira, A.3
Mascarenhas, P.4
Barahona, I.5
Moniz-Pereira, J.6
Gabuzda, D.7
Goncalves, J.8
-
42
-
-
0037225784
-
Immunomodulation of enzyme function in plants by single-domain antibody fragments
-
Jobling, S. A., Jarman, C., Teh, M. M., Holmberg, N., Blake, C., and Verhoeyen, M. E. (2003) Immunomodulation of enzyme function in plants by single-domain antibody fragments. Nat. Biotechnol. 21, 77-80
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 77-80
-
-
Jobling, S.A.1
Jarman, C.2
Teh, M.M.3
Holmberg, N.4
Blake, C.5
Verhoeyen, M.E.6
-
43
-
-
58949094406
-
Llama-derived single-domain intrabodies inhibit secretion of hepatitis B virions in mice
-
Serruys, B., Van Houtte, F., Verbrugghe, P., Leroux-Roels, G., and Vanlandschoot, P. (2009) Llama-derived single-domain intrabodies inhibit secretion of hepatitis B virions in mice. Hepatology 49, 39-49
-
(2009)
Hepatology
, vol.49
, pp. 39-49
-
-
Serruys, B.1
Van Houtte, F.2
Verbrugghe, P.3
Leroux-Roels, G.4
Vanlandschoot, P.5
-
44
-
-
75149169810
-
An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling
-
Delanote, V., Vanloo, B., Catillon, M., Friederich, E., Vandekerckhove, J., and Gettemans, J. (2010) An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling. FASEB J. 24, 105-118
-
(2010)
FASEB J.
, vol.24
, pp. 105-118
-
-
Delanote, V.1
Vanloo, B.2
Catillon, M.3
Friederich, E.4
Vandekerckhove, J.5
Gettemans, J.6
-
45
-
-
77954356408
-
An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 REV prevents viral production
-
Vercruysse, T., Pardon, E., Vanstreels, E., Steyaert, J., and Daelemans, D. (2010) An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 REV prevents viral production. J. Biol. Chem.
-
(2010)
J. Biol. Chem.
-
-
Vercruysse, T.1
Pardon, E.2
Vanstreels, E.3
Steyaert, J.4
Daelemans, D.5
-
46
-
-
17844406602
-
Bacterial cytotoxins: Targeting eukaryotic switches
-
Aktories, K., and Barbieri, J. T. (2005) Bacterial cytotoxins: targeting eukaryotic switches. Nat. Rev. Microbiol. 3, 397-410
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 397-410
-
-
Aktories, K.1
Barbieri, J.T.2
-
47
-
-
0034878448
-
Understanding the mode of action of diphtheria toxin: A perspective on progress during the 20th century
-
Collier, R. J. (2001) Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century. Toxicon 39, 1793-1803
-
(2001)
Toxicon
, vol.39
, pp. 1793-1803
-
-
Collier, R.J.1
-
48
-
-
74849098405
-
Treatment with monoclonal antibodies against Clostridium difficile toxins
-
Lowy, I., Molrine, D. C., Leav, B. A., Blair, B. M., Baxter, R., Gerding, D. N., Nichol, G., Thomas, W. D., Jr., Leney, M., Sloan, S., Hay, C. A., and Ambrosino, D. M. Treatment with monoclonal antibodies against Clostridium difficile toxins. N. Engl. J. Med. 362, 197-205
-
N. Engl. J. Med.
, vol.362
, pp. 197-205
-
-
Lowy, I.1
Molrine, D.C.2
Leav, B.A.3
Blair, B.M.4
Baxter, R.5
Gerding, D.N.6
Nichol, G.7
Thomas Jr., W.D.8
Leney, M.9
Sloan, S.10
Hay, C.A.11
Ambrosino, D.M.12
-
49
-
-
0026716655
-
Adjuvant properties of stable water-in-oil emulsions: Evaluation of the experience with Specol
-
Boersma, W. J., Bogaerts, W. J., Bianchi, A. T., and Claassen, E. (1992) Adjuvant properties of stable water-in-oil emulsions: evaluation of the experience with Specol. Res. Immunol. 143, 503-512
-
(1992)
Res. Immunol.
, vol.143
, pp. 503-512
-
-
Boersma, W.J.1
Bogaerts, W.J.2
Bianchi, A.T.3
Claassen, E.4
-
50
-
-
19444383993
-
Llama single domain antibodies as a tool for molecular mimicry
-
Zarebski, L. M., Urrutia, M., and Goldbaum, F. A. (2005) Llama single domain antibodies as a tool for molecular mimicry. J. Mol. Biol. 349, 814-824
-
(2005)
J. Mol. Biol.
, vol.349
, pp. 814-824
-
-
Zarebski, L.M.1
Urrutia, M.2
Goldbaum, F.A.3
-
51
-
-
55849135165
-
Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies
-
Ratier, L., Urrutia, M., Paris, G., Zarebski, L., Frasch, A. C., and Goldbaum, F. A. (2008) Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies. PLoS ONE 3, e3524
-
(2008)
PLoS ONE
, vol.3
, pp. 3524
-
-
Ratier, L.1
Urrutia, M.2
Paris, G.3
Zarebski, L.4
Frasch, A.C.5
Goldbaum, F.A.6
-
52
-
-
0019427215
-
Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin
-
Kouyama, T., and Mihashi, K. (1981) Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin. Eur. J. Biochem. 114, 33-38
-
(1981)
Eur. J. Biochem.
, vol.114
, pp. 33-38
-
-
Kouyama, T.1
Mihashi, K.2
-
53
-
-
0035715877
-
Single domain camel antibodies: Current status
-
Muyldermans, S. (2001) Single domain camel antibodies: current status. J. Biotechnol. 74, 277-302
-
(2001)
J. Biotechnol.
, vol.74
, pp. 277-302
-
-
Muyldermans, S.1
-
54
-
-
0038222529
-
Extracellular secretion of the virulence plasmid-encoded ADP-ribosyltransferase SpvB in Salmonella
-
Gotoh, H., Okada, N., Kim, Y. G., Shiraishi, K., Hirami, N., Haneda, T., Kurita, A., Kikuchi, Y., and Danbara, H. (2003) Extracellular secretion of the virulence plasmid-encoded ADP-ribosyltransferase SpvB in Salmonella. Microb. Pathog. 34, 227-238
-
(2003)
Microb. Pathog.
, vol.34
, pp. 227-238
-
-
Gotoh, H.1
Okada, N.2
Kim, Y.G.3
Shiraishi, K.4
Hirami, N.5
Haneda, T.6
Kurita, A.7
Kikuchi, Y.8
Danbara, H.9
-
55
-
-
34249854870
-
A cell-permeable fusion toxin as a tool to study the consequences of actin-ADP-ribosylation caused by the Salmonella enterica virulence factor SpvB in intact cells
-
Pust, S., Hochmann, H., Kaiser, E., von Figura, G., Heine, K., Aktories, K., and Barth, H. (2007) A cell-permeable fusion toxin as a tool to study the consequences of actin-ADP-ribosylation caused by the Salmonella enterica virulence factor SpvB in intact cells. J. Biol. Chem. 282, 10272-10282
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10272-10282
-
-
Pust, S.1
Hochmann, H.2
Kaiser, E.3
Von Figura, G.4
Heine, K.5
Aktories, K.6
Barth, H.7
-
56
-
-
0022641097
-
Botulinum C2 toxin ADP-ribosylates actin
-
Aktories, K., Barmann, M., Ohishi, I., Tsuyama, S., Jakobs, K. H., and Habermann, E. (1986) Botulinum C2 toxin ADP-ribosylates actin. Nature 322, 390-392
-
(1986)
Nature
, vol.322
, pp. 390-392
-
-
Aktories, K.1
Barmann, M.2
Ohishi, I.3
Tsuyama, S.4
Jakobs, K.H.5
Habermann, E.6
-
57
-
-
0039003839
-
Cellular uptake of Clostridium botulinum C2 toxin requires oligomerization and acidification
-
Barth, H., Blocker, D., Behlke, J., Bergsma-Schutter, W., Brisson, A., Benz, R., and Aktories, K. (2000) Cellular uptake of Clostridium botulinum C2 toxin requires oligomerization and acidification. J. Biol. Chem. 275, 18704-18711
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18704-18711
-
-
Barth, H.1
Blocker, D.2
Behlke, J.3
Bergsma-Schutter, W.4
Brisson, A.5
Benz, R.6
Aktories, K.7
-
58
-
-
0141816702
-
A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival
-
Cohen-Saidon, C., Nechushtan, H., Kahlon, S., Livni, N., Nissim, A., and Razin, E. (2003) A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival. Blood 102, 2506-2512
-
(2003)
Blood
, vol.102
, pp. 2506-2512
-
-
Cohen-Saidon, C.1
Nechushtan, H.2
Kahlon, S.3
Livni, N.4
Nissim, A.5
Razin, E.6
-
59
-
-
42049097657
-
Internalization via Antennapedia protein transduction domain of an scFv antibody toward c-Myc protein
-
Avignolo, C., Bagnasco, L., Biasotti, B., Melchiori, A., Tomati, V., Bauer, I., Salis, A., Chiossone, L., Mingari, M. C., Orecchia, P., Carnemolla, B., Neri, D., Zardi, L., and Parodi, S. (2008) Internalization via Antennapedia protein transduction domain of an scFv antibody toward c-Myc protein. FASEB J. 22, 1237-1245
-
(2008)
FASEB J.
, vol.22
, pp. 1237-1245
-
-
Avignolo, C.1
Bagnasco, L.2
Biasotti, B.3
Melchiori, A.4
Tomati, V.5
Bauer, I.6
Salis, A.7
Chiossone, L.8
Mingari, M.C.9
Orecchia, P.10
Carnemolla, B.11
Neri, D.12
Zardi, L.13
Parodi, S.14
-
60
-
-
25444513373
-
Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/ CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction
-
Granelli-Piperno, A., Pritsker, A., Pack, M., Shimeliovich, I., Arrighi, J. F., Park, C. G., Trumpfheller, C., Piguet, V., Moran, T. M., and Steinman, R. M. (2005) Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/ CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction. J. Immunol. 175, 4265-4273
-
(2005)
J. Immunol.
, vol.175
, pp. 4265-4273
-
-
Granelli-Piperno, A.1
Pritsker, A.2
Pack, M.3
Shimeliovich, I.4
Arrighi, J.F.5
Park, C.G.6
Trumpfheller, C.7
Piguet, V.8
Moran, T.M.9
Steinman, R.M.10
-
61
-
-
33644508625
-
A synthetic camel anti-lysozyme peptide antibody (peptibody) with flexible loop structure identified by high-resolution affinity mass spectrometry
-
Marquardt, A., Muyldermans, S., and Przybylski, M. (2006) A synthetic camel anti-lysozyme peptide antibody (peptibody) with flexible loop structure identified by high-resolution affinity mass spectrometry. Chemistry (Weinheim an der Bergstrasse, Germany) 12, 1915-1923
-
(2006)
Chemistry (Weinheim An der Bergstrasse, Germany)
, vol.12
, pp. 1915-1923
-
-
Marquardt, A.1
Muyldermans, S.2
Przybylski, M.3
-
62
-
-
53849133471
-
Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins
-
Deng, Q., and Barbieri, J. T. (2008) Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins. Annu. Rev. Microbiol. 62, 271-288
-
(2008)
Annu. Rev. Microbiol.
, vol.62
, pp. 271-288
-
-
Deng, Q.1
Barbieri, J.T.2
-
63
-
-
59849110833
-
Role of Pseudomonas aeruginosa type III effectors in disease
-
Engel, J., and Balachandran, P. (2009) Role of Pseudomonas aeruginosa type III effectors in disease. Curr. Opin. Microbiol. 12, 61-66
-
(2009)
Curr. Opin. Microbiol.
, vol.12
, pp. 61-66
-
-
Engel, J.1
Balachandran, P.2
-
64
-
-
33748630780
-
The Salmonella effector protein PipB2 is a linker for kinesin-1
-
Henry, T., Couillault, C., Rockenfeller, P., Boucrot, E., Dumont, A., Schroeder, N., Hermant, A., Knodler, L. A., Lecine, P., Steele-Mortimer, O., Borg, J. P., Gorvel, J. P., and Meresse, S. (2006) The Salmonella effector protein PipB2 is a linker for kinesin-1. Proc. Natl. Acad. Sci. U. S. A. 103, 13497-13502
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 13497-13502
-
-
Henry, T.1
Couillault, C.2
Rockenfeller, P.3
Boucrot, E.4
Dumont, A.5
Schroeder, N.6
Hermant, A.7
Knodler, L.A.8
Lecine, P.9
Steele-Mortimer, O.10
Borg, J.P.11
Gorvel, J.P.12
Meresse, S.13
-
65
-
-
0031864184
-
Type III protein secretion systems in bacterial pathogens of animals and plants
-
Hueck, C. J. (1998) Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 62, 379-433
-
(1998)
Microbiol. Mol. Biol. Rev.
, vol.62
, pp. 379-433
-
-
Hueck, C.J.1
-
66
-
-
0033591446
-
Type III secretion machines: Bacterial devices for protein delivery into host cells
-
Galan, J. E., and Collmer, A. (1999) Type III secretion machines: bacterial devices for protein delivery into host cells. Science 284, 1322-1328
-
(1999)
Science
, vol.284
, pp. 1322-1328
-
-
Galan, J.E.1
Collmer, A.2
|