Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies

PLoS ONE

Volumn 3, Issue 10, 2008, Pages

  Ratier, Laura ^a   Urrutia, Mariela ^b   Paris, Gastón ^b   Zarebski, Laura ^b,c   Frasch, Alberto C ^a   Goldbaum, Fernando A ^b  

^a INSTITUTO DE INVESTIGACIONES BIOTECNOLÓGICAS   (Argentina)

^b FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^c Immune Epitope Database (IEDB)   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT ENZYME; RECOMBINANT SIALIDASE; SIALIDASE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; ANTIBODY; ENZYME INHIBITOR; IMMUNOGLOBULIN FRAGMENT; PEPTIDE LIBRARY;

ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIPROTOZOAL ACTIVITY; ARTICLE; ARTIODACTYLA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; GENE EXPRESSION; IMMUNIZATION; INNATE IMMUNITY; LIGAND BINDING; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SPECIES DIVERSITY; TRYPANOSOMA CRUZI; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY AFFINITY; ANTIGENIC VARIATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYMOLOGY; EPITOPE MAPPING; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE;

CAMELIDAE; LAMA (MAMMAL); LAMA GLAMA; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIBODY AFFINITY; ANTIGENIC VARIATION; CAMELIDS, NEW WORLD; CATALYTIC DOMAIN; ENZYME INHIBITORS; EPITOPE MAPPING; IMMUNOGLOBULIN FRAGMENTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURAMINIDASE; PEPTIDE LIBRARY; PROTEIN STRUCTURE, TERTIARY; TRYPANOSOMA CRUZI;

EID: 55849135165     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003524     Document Type: Article

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