Internalization via Antennapedia protein transduction domain of an scFv antibody toward c-Myc protein

FASEB Journal

Volumn 22, Issue 4, 2008, Pages 1237-1245

  Avignolo, C ^a,b   Bagnasco, L ^a,b   Biasotti, B ^a,b   Melchiori, A ^b   Tomati, V ^a   Bauer, I ^a   Salis, A ^a   Chiossone, L ^b   Mingari, M C ^a,b   Orecchia, P ^c   Carnemolla, B ^b   Neri, D ^d   Zardi, L ^e   Parodi, S ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c G GASLINI INSTITUTE   (Italy)

^d ETH ZURICH   (Switzerland)

^e Advanced Biotechnology Centre   (Italy)

Author keywords

Fluorescence labeling; Intracellular delivery; Miniantibody; Oncoprotein targeting; PTD

Indexed keywords

ANTENNAPEDIA PROTEIN; HYBRID PROTEIN; MYC PROTEIN; PHENYLALANYLLEUCYLARGINYLGLUTAMINYLISOLEUCYLLYSYLISOLEUCYL TRYPTOPHYLPHENYLALANYLGLUTAMINYLASPARAGINYLARGINYLARGINYL METHIONYLLYSYLTRYPTOPHYLLYSYLLYSINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL MEMBRANE; CELL NUCLEUS; CONCENTRATION (PARAMETERS); CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH INHIBITION; HUMAN; HUMAN CELL; INCUBATION TIME; INTERNALIZATION; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN DOMAIN; STATISTICAL ANALYSIS;

ANTENNAPEDIA HOMEODOMAIN PROTEIN; ANTIBODIES, MONOCLONAL; CELL NUCLEUS; HCT116 CELLS; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINANT FUSION PROTEINS;

EID: 42049097657     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8865com     Document Type: Article

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