Development of new folate-based PET radiotracers: Preclinical evaluation of 68Ga-DOTA-folate conjugates

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 38, Issue 1, 2011, Pages 108-119

  Fani, Melpomeni ^a,c   Wang, Xuejuan ^a   Nicolas, Guillaume ^a   Medina, Christelle ^b   Raynal, Isabelle ^b   Port, Marc ^b   Maecke, Helmut R ^a,c  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Research Department   (France)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

68Ga; DOTA folate conjugates; Folate receptor; PET imaging

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; ETHYLENEDIAMINE; FOLATE RECEPTOR; FOLIC ACID; GALLIUM 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID FOLATE GA 67; GALLIUM 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID FOLATE GA 68; GALLIUM 67; GALLIUM 68; PENTETATE FOLATE INDIUM IN 111; PENTETATE INDIUM IN 111; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL STRAIN KB; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG TUMOR LEVEL; FEMALE; FIBROSARCOMA; HUMAN; HUMAN CELL; INTERNALIZATION; ISOTOPE LABELING; KIDNEY; MOUSE; MOUTH CANCER; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DISTRIBUTION;

ANIMALS; BIOLOGICAL TRANSPORT; DRUG EVALUATION, PRECLINICAL; FEMALE; FOLIC ACID; FOLIC ACID TRANSPORTERS; GALLIUM RADIOISOTOPES; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; KB CELLS; MICE; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 79551517797     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-010-1597-8     Document Type: Article

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