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Volumn 36, Issue 6, 2009, Pages 938-946

Evaluation of a novel radiofolate in tumour-bearing mice: Promising prospects for folate-based radionuclide therapy

Author keywords

177Lu; DOTA folate; Folate receptor; Pemetrexed; SPECT CT

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID FOLATE INDIUM CHLORIDE IN 111 CONJUGATE; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID FOLATE LUTETIUM CHLORIDE LU 177 CONJUGATE; FOLIC ACID DERIVATIVE; INDIUM CHLORIDE IN 111; LUTETIUM 177; PEMETREXED; RADIOISOTOPE; UNCLASSIFIED DRUG;

EID: 67349088706     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-1058-9     Document Type: Article
Times cited : (50)

References (55)
  • 1
    • 0026752798 scopus 로고
    • Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues
    • SD Weitman RH Lark LR Coney 1992 Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues Cancer Res 52 3396 3401
    • (1992) Cancer Res , vol.52 , pp. 3396-3401
    • Weitman, S.D.1    Lark, R.H.2    Coney, L.R.3
  • 2
    • 0027406702 scopus 로고
    • Trophoblast and ovarian cancer antigen LK26 - Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein
    • P Garin-Chesa I Campbell PE Saigo 1993 Trophoblast and ovarian cancer antigen LK26 - sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein Am J Pathol 142 557 567
    • (1993) Am J Pathol , vol.142 , pp. 557-567
    • Garin-Chesa, P.1    Campbell, I.2    Saigo, P.E.3
  • 3
    • 0030910859 scopus 로고    scopus 로고
    • Overexpression of folate binding protein in ovarian cancers
    • G Toffoli C Cernigoi A Russo 1997 Overexpression of folate binding protein in ovarian cancers Int J Cancer 74 193 198
    • (1997) Int J Cancer , vol.74 , pp. 193-198
    • Toffoli, G.1    Cernigoi, C.2    Russo, A.3
  • 4
    • 14644392093 scopus 로고    scopus 로고
    • Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
    • N Parker MJ Turk E Westrick 2005 Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay Anal Biochem 338 284 293
    • (2005) Anal Biochem , vol.338 , pp. 284-293
    • Parker, N.1    Turk, M.J.2    Westrick, E.3
  • 5
    • 1942503257 scopus 로고    scopus 로고
    • Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis
    • CM Paulos MJ Turk GJ Breur PS Low 2004 Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis Adv Drug Deliv Rev 56 1205 1217
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1205-1217
    • Paulos, C.M.1    Turk, M.J.2    Breur, G.J.3    Low, P.S.4
  • 6
    • 0032588840 scopus 로고    scopus 로고
    • 99mTc-HYNIC-folate: A novel receptor-based targeted radiopharmaceutical for tumor imaging
    • 99mTc-HYNIC-folate: a novel receptor-based targeted radiopharmaceutical for tumor imaging J Nucl Med 40 1563 1569
    • (1999) J Nucl Med , vol.40 , pp. 1563-1569
    • Guo, W.J.1    Hinkle, G.H.2    Lee, R.J.3
  • 7
    • 0033625094 scopus 로고    scopus 로고
    • 99mTc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical
    • 99mTc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical Bioconjug Chem 11 253 257
    • (2000) Bioconjug Chem , vol.11 , pp. 253-257
    • Mathias, C.J.1    Hubers, D.2    Low, P.S.3    Green, M.A.4
  • 12
    • 0038621645 scopus 로고    scopus 로고
    • 111In-DTPA-folate as a receptor-targeted diagnostic agent for ovarian cancer: Initial clinical results
    • 111In-DTPA- folate as a receptor-targeted diagnostic agent for ovarian cancer: initial clinical results J Nucl Med 44 700 707
    • (2003) J Nucl Med , vol.44 , pp. 700-707
    • Siegel, B.A.1    Dehdashti, F.2    Mutch, D.G.3
  • 14
    • 0141448741 scopus 로고    scopus 로고
    • 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals
    • 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals Nucl Med Biol 30 725 731
    • (2003) Nucl Med Biol , vol.30 , pp. 725-731
    • Mathias, C.J.1    Lewis, M.R.2    Reichert, D.E.3
  • 15
    • 33747135111 scopus 로고    scopus 로고
    • 18F for PET imaging of folate receptor-positive tumors
    • 18F for PET imaging of folate receptor-positive tumors J Nucl Med 47 1153 1160
    • (2006) J Nucl Med , vol.47 , pp. 1153-1160
    • Bettio, A.1    Honer, M.2    Müller, C.3
  • 16
    • 0347224284 scopus 로고    scopus 로고
    • The folate receptor as a molecular target for tumor-selective radionuclide delivery
    • CY Ke CJ Mathias MA Green 2003 The folate receptor as a molecular target for tumor-selective radionuclide delivery Nucl Med Biol 30 811 817
    • (2003) Nucl Med Biol , vol.30 , pp. 811-817
    • Ke, C.Y.1    Mathias, C.J.2    Green, M.A.3
  • 17
    • 16544383488 scopus 로고    scopus 로고
    • Folate-receptor-targeted radionuclide imaging agents
    • CY Ke CJ Mathias MA Green 2004 Folate-receptor-targeted radionuclide imaging agents Adv Drug Deliv Rev 56 1143 1160
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1143-1160
    • Ke, C.Y.1    Mathias, C.J.2    Green, M.A.3
  • 19
    • 1942439013 scopus 로고    scopus 로고
    • Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates
    • A Gabizon H Shmeeda AT Horowitz S Zalipsky 2004 Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates Adv Drug Deliv Rev 56 1177 1192
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1177-1192
    • Gabizon, A.1    Shmeeda, H.2    Horowitz, A.T.3    Zalipsky, S.4
  • 20
    • 1942439012 scopus 로고    scopus 로고
    • Tumor-selective targeted delivery of genes and antisense oligodeoxyribonucleotides via the folate receptor
    • XBB Zhao RJ Lee 2004 Tumor-selective targeted delivery of genes and antisense oligodeoxyribonucleotides via the folate receptor Adv Drug Deliv Rev 56 1193 1204
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1193-1204
    • Zhao, X.B.B.1    Lee, R.J.2
  • 21
    • 0141955901 scopus 로고    scopus 로고
    • Immunotherapy of folate receptor-expressing tumors: Review of recent advances and future prospects
    • Y Lu PS Low 2003 Immunotherapy of folate receptor-expressing tumors: review of recent advances and future prospects J Control Release 91 17 29
    • (2003) J Control Release , vol.91 , pp. 17-29
    • Lu, Y.1    Low, P.S.2
  • 22
    • 1942503277 scopus 로고    scopus 로고
    • Folate receptor-targeted immunotherapy of cancer: Mechanism and therapeutic potential
    • YJ Lu E Sega CP Leamon PS Low 2004 Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential Adv Drug Deliv Rev 56 1161 1176
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1161-1176
    • Lu, Y.J.1    Sega, E.2    Leamon, C.P.3    Low, P.S.4
  • 23
    • 22644434396 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of EC72: A new folate-targeted chemotherapeutic
    • CP Leamon JA Reddy IR Vlahov 2005 Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic Bioconjug Chem 16 803 811
    • (2005) Bioconjug Chem , vol.16 , pp. 803-811
    • Leamon, C.P.1    Reddy, J.A.2    Vlahov, I.R.3
  • 24
    • 34447128803 scopus 로고    scopus 로고
    • Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate
    • JA Reddy E Westrick HK Santhapuram 2007 Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate Cancer Res 67 6376 6382
    • (2007) Cancer Res , vol.67 , pp. 6376-6382
    • Reddy, J.A.1    Westrick, E.2    Santhapuram, H.K.3
  • 25
    • 33749034747 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of EC140: A novel folate-targeted vinca alkaloid conjugate
    • CP Leamon JA Reddy IR Vlahov 2006 Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate Bioconjug Chem 17 1226 1232
    • (2006) Bioconjug Chem , vol.17 , pp. 1226-1232
    • Leamon, C.P.1    Reddy, J.A.2    Vlahov, I.R.3
  • 26
    • 34249321972 scopus 로고    scopus 로고
    • Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate
    • JA Reddy R Dorton E Westrick 2007 Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate Cancer Res 67 4434 4442
    • (2007) Cancer Res , vol.67 , pp. 4434-4442
    • Reddy, J.A.1    Dorton, R.2    Westrick, E.3
  • 27
    • 0031658693 scopus 로고    scopus 로고
    • Indium-111-DTPA-folate as a potential folate-receptor-targeted radiopharmaceutical
    • CJ Mathias S Wang DJ Waters 1998 Indium-111-DTPA-folate as a potential folate-receptor-targeted radiopharmaceutical J Nucl Med 39 1579 1585
    • (1998) J Nucl Med , vol.39 , pp. 1579-1585
    • Mathias, C.J.1    Wang, S.2    Waters, D.J.3
  • 29
    • 0026542407 scopus 로고
    • A high-affinity folate binding-protein in proximal tubule cells of human kidney
    • J Holm SI Hansen M Hoiermadsen L Bostad 1992 A high-affinity folate binding-protein in proximal tubule cells of human kidney Kidney Int 41 50 55
    • (1992) Kidney Int , vol.41 , pp. 50-55
    • Holm, J.1    Hansen, S.I.2    Hoiermadsen, M.3    Bostad, L.4
  • 32
    • 3242726883 scopus 로고    scopus 로고
    • Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy
    • RM Sandoval MD Kennedy PS Low BA Molitoris 2004 Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy Am J Physiol Cell Physiol 287 C517 C526
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Sandoval, R.M.1    Kennedy, M.D.2    Low, P.S.3    Molitoris, B.A.4
  • 33
    • 34547831118 scopus 로고    scopus 로고
    • Effects of antifolate drugs on the cellular uptake of radiofolates in vitro and in vivo
    • C Müller M Brühlmeier AP Schubiger R Schibli 2006 Effects of antifolate drugs on the cellular uptake of radiofolates in vitro and in vivo J Nucl Med 47 2057 2064
    • (2006) J Nucl Med , vol.47 , pp. 2057-2064
    • Müller, C.1    Brühlmeier, M.2    Schubiger, A.P.3    Schibli, R.4
  • 35
    • 0034861227 scopus 로고    scopus 로고
    • Pemetrexed disodium: A novel antifolate clinically active against multiple solid tumors
    • AR Hanauske V Chen P Paoletti C Niyikiza 2001 Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors Oncologist 6 363 373
    • (2001) Oncologist , vol.6 , pp. 363-373
    • Hanauske, A.R.1    Chen, V.2    Paoletti, P.3    Niyikiza, C.4
  • 37
    • 34547830389 scopus 로고    scopus 로고
    • 188Re: A potential strategy for diagnosis and therapy of folate receptor-positive tumors
    • 188Re: a potential strategy for diagnosis and therapy of folate receptor-positive tumors Nucl Med Biol 34 595 601
    • (2007) Nucl Med Biol , vol.34 , pp. 595-601
    • Müller, C.1    Schubiger, P.A.2    Schibli, R.3
  • 41
    • 34147182966 scopus 로고    scopus 로고
    • 3]octreotate in patients with paraganglioma, meningioma, small cell lung carcinoma, and melanoma
    • 3]octreotate in patients with paraganglioma, meningioma, small cell lung carcinoma, and melanoma J Nucl Med 47 1599 1606
    • (2006) J Nucl Med , vol.47 , pp. 1599-1606
    • Van Essen, M.1    Krenning, E.P.2    Kooij, P.P.3
  • 42
    • 0000096835 scopus 로고    scopus 로고
    • Click chemistry: Diverse chemical function from a few good reactions
    • HC Kolb MG Finn KB Sharpless 2001 Click chemistry: diverse chemical function from a few good reactions Angew Chem Int Ed Engl 40 2004 2021
    • (2001) Angew Chem Int Ed Engl , vol.40 , pp. 2004-2021
    • Kolb, H.C.1    Finn, M.G.2    Sharpless, K.B.3
  • 43
    • 0348109450 scopus 로고    scopus 로고
    • The growing impact of click chemistry on drug discovery
    • HC Kolb KB Sharpless 2003 The growing impact of click chemistry on drug discovery Drug Discov Today 8 1128 1137
    • (2003) Drug Discov Today , vol.8 , pp. 1128-1137
    • Kolb, H.C.1    Sharpless, K.B.2
  • 44
    • 34547211994 scopus 로고    scopus 로고
    • Synthesis of novel 1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid (DOTA) derivatives for chemoselective attachment to unprotected polyfunctionalized compounds
    • S Knör A Modlinger T Poethko 2007 Synthesis of novel 1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid (DOTA) derivatives for chemoselective attachment to unprotected polyfunctionalized compounds Chemistry 13 6082 6090
    • (2007) Chemistry , vol.13 , pp. 6082-6090
    • Knör, S.1    Modlinger, A.2    Poethko, T.3
  • 45
    • 33847751474 scopus 로고    scopus 로고
    • Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: Implications for tumor targeting and tumor imaging purposes
    • I Dijkgraaf AY Rijnders A Soede 2007 Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes Org Biomol Chem 5 935 944
    • (2007) Org Biomol Chem , vol.5 , pp. 935-944
    • Dijkgraaf, I.1    Rijnders, A.Y.2    Soede, A.3
  • 47
    • 0036009647 scopus 로고    scopus 로고
    • Effects of coligand variation on the in vivo characteristics of Tc-99m-labeled interleukin-8 in detection of infection
    • HJJM Rennen JE van Eerd WJG Oyen 2002 Effects of coligand variation on the in vivo characteristics of Tc-99m-labeled interleukin-8 in detection of infection Bioconjug Chem 13 370 377
    • (2002) Bioconjug Chem , vol.13 , pp. 370-377
    • Hjjm, R.1    Van Eerd, J.E.2    Oyen, W.J.G.3
  • 48
    • 0027058186 scopus 로고
    • Effects of folate receptor expression following stable transfection into wild type and methotrexate transport-deficient ZR-75-1 human breast cancer cells
    • KH Dixon T Mulligan KN Chung PC Elwood KH Cowan 1992 Effects of folate receptor expression following stable transfection into wild type and methotrexate transport-deficient ZR-75-1 human breast cancer cells J Biol Chem 267 24140 24147
    • (1992) J Biol Chem , vol.267 , pp. 24140-24147
    • Dixon, K.H.1    Mulligan, T.2    Chung, K.N.3    Elwood, P.C.4    Cowan, K.H.5
  • 50
    • 0030163022 scopus 로고    scopus 로고
    • Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of gallium-67-deferoxamine-folate
    • CJ Mathias S Wang RJ Lee 1996 Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of gallium-67-deferoxamine-folate J Nucl Med 37 1003 1008
    • (1996) J Nucl Med , vol.37 , pp. 1003-1008
    • Mathias, C.J.1    Wang, S.2    Lee, R.J.3
  • 51
    • 33749243966 scopus 로고    scopus 로고
    • In vivo radionuclide uptake quantification using a multi-pinhole SPECT system to predict renal function in small animals
    • F Forrer R Valkema B Bernard 2006 In vivo radionuclide uptake quantification using a multi-pinhole SPECT system to predict renal function in small animals Eur J Nucl Med Mol Imaging 33 1214 1217
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 1214-1217
    • Forrer, F.1    Valkema, R.2    Bernard, B.3
  • 53
    • 0027283362 scopus 로고
    • Amino acid infusion blocks renal tubular uptake of an indium-labelled somatostatin analogue
    • PJ Hammond AF Wade ME Gwilliam 1993 Amino acid infusion blocks renal tubular uptake of an indium-labelled somatostatin analogue Br J Cancer 67 1437 1439
    • (1993) Br J Cancer , vol.67 , pp. 1437-1439
    • Hammond, P.J.1    Wade, A.F.2    Gwilliam, M.E.3
  • 54
    • 46849106280 scopus 로고    scopus 로고
    • Renal uptake and metabolism of radiopharmaceuticals derived from peptides and proteins
    • H Akizawa T Uehara Y Arano 2008 Renal uptake and metabolism of radiopharmaceuticals derived from peptides and proteins Adv Drug Deliv Rev 60 1319 1328
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1319-1328
    • Akizawa, H.1    Uehara, T.2    Arano, Y.3
  • 55
    • 34247895618 scopus 로고    scopus 로고
    • 3]-octreotate: Uptake and dosimetry in somatostatin receptor-positive tumors and normal organs
    • 3]-octreotate: uptake and dosimetry in somatostatin receptor-positive tumors and normal organs Cancer Biother Radiopharm 22 151 159
    • (2007) Cancer Biother Radiopharm , vol.22 , pp. 151-159
    • Müller, C.1    Forrer, F.2    Bernard, B.F.3


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