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Volumn 112, Issue 2, 2011, Pages 643-652

Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer

Author keywords

CHOP; colon cancer; ER stress; GRP78; GSK3

Indexed keywords

3,6 BIS(3 CHLOROPHENYLACETYL)PHLOROGLUCINOL; CASPASE 3; CASPASE 7; CASPASE 9; CCAAT ENHANCER BINDING PROTEIN; GLUCOSE REGULATED PROTEIN 78; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INITIATION FACTOR 2ALPHA; PHLOROGLUCINOL DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79251629978     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22966     Document Type: Article
Times cited : (37)

References (36)
  • 1
    • 0036328117 scopus 로고    scopus 로고
    • Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress
    • Abcouwer SF, Marjon PL, Loper RK, Vander Jagt DL,. 2002. Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress. Invest Ophthalmol Vis Sci 43: 2791-2798.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 2791-2798
    • Abcouwer, S.F.1    Marjon, P.L.2    Loper, R.K.3    Vander Jagt, D.L.4
  • 4
    • 9444257518 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine- induced neuronal death
    • Chen G, Bower KA, Ma C, Fang S, Thiele CJ, Luo J,. 2004. Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death. FASEB J 18: 1162-1164.
    • (2004) FASEB J , vol.18 , pp. 1162-1164
    • Chen, G.1    Bower, K.A.2    Ma, C.3    Fang, S.4    Thiele, C.J.5    Luo, J.6
  • 5
    • 77949874077 scopus 로고    scopus 로고
    • Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress
    • Chen YJ, Wu CL, Liu JF, Fong YC, Hsu SF, Li TM, Su YC, Liu SH, Tang CH,. 2010. Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress. Cancer Lett 291: 20-30.
    • (2010) Cancer Lett , vol.291 , pp. 20-30
    • Chen, Y.J.1    Wu, C.L.2    Liu, J.F.3    Fong, Y.C.4    Hsu, S.F.5    Li, T.M.6    Su, Y.C.7    Liu, S.H.8    Tang, C.H.9
  • 6
    • 67649595826 scopus 로고    scopus 로고
    • Apoptosis and cancer: The genesis of a research field
    • Cotter TG,. 2009. Apoptosis and cancer: The genesis of a research field. Nat Rev Cancer 9: 501-507.
    • (2009) Nat Rev Cancer , vol.9 , pp. 501-507
    • Cotter, T.G.1
  • 7
    • 20344392461 scopus 로고    scopus 로고
    • Caspases-2, -3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells
    • Dahmer MK,. 2005. Caspases-2, -3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells. J Neurosci Res 80: 576-583.
    • (2005) J Neurosci Res , vol.80 , pp. 576-583
    • Dahmer, M.K.1
  • 8
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • Doble BW, Woodgett JR,. 2003. GSK-3: Tricks of the trade for a multi-tasking kinase. J Cell Sci 116 (Pt 7): 1175-1186.
    • (2003) J Cell Sci , vol.116 , Issue.PART 7 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 9
    • 28844470269 scopus 로고    scopus 로고
    • The unfolded protein response: A novel component of the hypoxic stress response in tumors
    • Feldman DE, Chauhan V, Koong AC,. 2005. The unfolded protein response: A novel component of the hypoxic stress response in tumors. Mol Cancer Res 3: 597-605.
    • (2005) Mol Cancer Res , vol.3 , pp. 597-605
    • Feldman, D.E.1    Chauhan, V.2    Koong, A.C.3
  • 10
    • 0029901711 scopus 로고    scopus 로고
    • GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells
    • Friedman AD,. 1996. GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells. Cancer Res 56: 3250-3256.
    • (1996) Cancer Res , vol.56 , pp. 3250-3256
    • Friedman, A.D.1
  • 11
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • Grimes CA, Jope RS,. 2001. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 65: 391-426.
    • (2001) Prog Neurobiol , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 12
    • 0036437307 scopus 로고    scopus 로고
    • Transcriptional and translational control in the mammalian unfolded protein response
    • Harding HP, Calfon M, Urano F, Novoa I, Ron D,. 2002. Transcriptional and translational control in the mammalian unfolded protein response. Annu Rev Cell Dev Biol 18: 575-599.
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 575-599
    • Harding, H.P.1    Calfon, M.2    Urano, F.3    Novoa, I.4    Ron, D.5
  • 13
    • 47349090556 scopus 로고    scopus 로고
    • The role of glycogen synthase kinase-3beta in normal haematopoiesis, angiogenesis and leukaemia
    • Holmes T, O'Brien TA, Knight R, Lindeman R, Symonds G, Dolnikov A,. 2008. The role of glycogen synthase kinase-3beta in normal haematopoiesis, angiogenesis and leukaemia. Curr Med Chem 15: 1493-1499.
    • (2008) Curr Med Chem , vol.15 , pp. 1493-1499
    • Holmes, T.1    O'Brien, T.A.2    Knight, R.3    Lindeman, R.4    Symonds, G.5    Dolnikov, A.6
  • 14
    • 14044261099 scopus 로고    scopus 로고
    • Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
    • Kim AJ, Shi Y, Austin RC, Werstuck GH,. 2005. Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. J Cell Sci 118 (Pt 1): 89-99.
    • (2005) J Cell Sci , vol.118 , Issue.PART 1 , pp. 89-99
    • Kim, A.J.1    Shi, Y.2    Austin, R.C.3    Werstuck, G.H.4
  • 15
    • 31644447446 scopus 로고    scopus 로고
    • Increased expression of GRP94 protein is associated with decreased sensitivity to X-rays in cervical cancer cell lines
    • Kubota H, Suzuki T, Lu J, Takahashi S, Sugita K, Sekiya S, Suzuki N,. 2005. Increased expression of GRP94 protein is associated with decreased sensitivity to X-rays in cervical cancer cell lines. Int J Radiat Biol 81 (9): 701-709.
    • (2005) Int J Radiat Biol , vol.81 , Issue.9 , pp. 701-709
    • Kubota, H.1    Suzuki, T.2    Lu, J.3    Takahashi, S.4    Sugita, K.5    Sekiya, S.6    Suzuki, N.7
  • 16
    • 25444529205 scopus 로고    scopus 로고
    • A cytotoxic triketone-phloroglucinol-bullatenone hybrid from Lophomyrtus bullata
    • Larsen L, Benn MH, Parvez M, Perry NB,. 2005. A cytotoxic triketone-phloroglucinol-bullatenone hybrid from Lophomyrtus bullata. Org Biomol Chem 3: 3236-3241.
    • (2005) Org Biomol Chem , vol.3 , pp. 3236-3241
    • Larsen, L.1    Benn, M.H.2    Parvez, M.3    Perry, N.B.4
  • 17
    • 77957141008 scopus 로고    scopus 로고
    • Still embedded together binding to membranes regulates Bcl-2 protein interactions
    • Leber B, Lin J, Andrews DW,. 2010. Still embedded together binding to membranes regulates Bcl-2 protein interactions. Oncogene 29: 5221-5230.
    • (2010) Oncogene , vol.29 , pp. 5221-5230
    • Leber, B.1    Lin, J.2    Andrews, D.W.3
  • 18
    • 0035423875 scopus 로고    scopus 로고
    • The glucose-regulated proteins: Stress induction and clinical applications
    • Lee AS,. 2001. The glucose-regulated proteins: Stress induction and clinical applications. Trends Biochem Sci 26: 504-510.
    • (2001) Trends Biochem Sci , vol.26 , pp. 504-510
    • Lee, A.S.1
  • 19
    • 77649185144 scopus 로고    scopus 로고
    • BFPP, a phloroglucinol derivative, induces cell apoptosis in human chondrosarcoma cells through endoplasmic reticulum stress
    • Liu JF, Yang WH, Fong YC, Kuo SC, Chang CS, Tang CH,. 2010. BFPP, a phloroglucinol derivative, induces cell apoptosis in human chondrosarcoma cells through endoplasmic reticulum stress. Biochem Pharmacol 79: 1410-1417.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1410-1417
    • Liu, J.F.1    Yang, W.H.2    Fong, Y.C.3    Kuo, S.C.4    Chang, C.S.5    Tang, C.H.6
  • 20
    • 53849097672 scopus 로고    scopus 로고
    • Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells
    • Lim JH, Park JW, Kim SH, Choi YH, Choi KS, Kwon TK,. 2008. Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells. Apoptosis 13: 1378-1385.
    • (2008) Apoptosis , vol.13 , pp. 1378-1385
    • Lim, J.H.1    Park, J.W.2    Kim, S.H.3    Choi, Y.H.4    Choi, K.S.5    Kwon, T.K.6
  • 21
    • 65549101773 scopus 로고    scopus 로고
    • Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells
    • Lim JH, Park JW, Choi KS, Park YB, Kwon TK,. 2009. Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells. Carcinogenesis 30: 729-736.
    • (2009) Carcinogenesis , vol.30 , pp. 729-736
    • Lim, J.H.1    Park, J.W.2    Choi, K.S.3    Park, Y.B.4    Kwon, T.K.5
  • 22
    • 34347218245 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced death of mouse embryonic fibroblasts requires the intrinsic pathway of apoptosis
    • Masud A, Mohapatra A, Lakhani SA, Ferrandino A, Hakem R, Flavell RA,. 2007. Endoplasmic reticulum stress-induced death of mouse embryonic fibroblasts requires the intrinsic pathway of apoptosis. J Biol Chem 282: 14132-14139.
    • (2007) J Biol Chem , vol.282 , pp. 14132-14139
    • Masud, A.1    Mohapatra, A.2    Lakhani, S.A.3    Ferrandino, A.4    Hakem, R.5    Flavell, R.A.6
  • 23
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ,. 2001. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21: 1249-1259.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 24
    • 36348943088 scopus 로고    scopus 로고
    • Integrated endoplasmic reticulum stress responses in cancer
    • Moenner M, Pluquet O, Bouchecareilh M, Chevet E,. 2007. Integrated endoplasmic reticulum stress responses in cancer. Cancer Res 67: 10631-10634.
    • (2007) Cancer Res , vol.67 , pp. 10631-10634
    • Moenner, M.1    Pluquet, O.2    Bouchecareilh, M.3    Chevet, E.4
  • 25
  • 26
    • 33747615945 scopus 로고    scopus 로고
    • Hyperforin, a new lead compound against the progression of cancer and leukemia?
    • Quiney C, Billard C, Salanoubat C, Fourneron JD, Kolb JP,. 2006. Hyperforin, a new lead compound against the progression of cancer and leukemia? Leukemia 20: 1519-1525.
    • (2006) Leukemia , vol.20 , pp. 1519-1525
    • Quiney, C.1    Billard, C.2    Salanoubat, C.3    Fourneron, J.D.4    Kolb, J.P.5
  • 29
    • 1842843860 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program
    • Rao RV, Ellerby HM, Bredesen DE,. 2004. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 11: 372-380.
    • (2004) Cell Death Differ , vol.11 , pp. 372-380
    • Rao, R.V.1    Ellerby, H.M.2    Bredesen, D.E.3
  • 30
    • 0038080911 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation
    • Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS,. 2003. Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation. J Biol Chem 278: 20915-20924.
    • (2003) J Biol Chem , vol.278 , pp. 20915-20924
    • Reddy, R.K.1    Mao, C.2    Baumeister, P.3    Austin, R.C.4    Kaufman, R.J.5    Lee, A.S.6
  • 31
    • 0037133929 scopus 로고    scopus 로고
    • 2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells
    • 2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. J Biol Chem 277: 13812-13820.
    • (2002) J Biol Chem , vol.277 , pp. 13812-13820
    • Soboloff, J.1    Berger, S.A.2
  • 32
    • 0037160134 scopus 로고    scopus 로고
    • Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation
    • Song L, De Sarno P, Jope RS,. 2002. Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J Biol Chem 277: 44701-44708.
    • (2002) J Biol Chem , vol.277 , pp. 44701-44708
    • Song, L.1    De Sarno, P.2    Jope, R.S.3
  • 33
    • 48249083788 scopus 로고    scopus 로고
    • Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: The protective role of autophagy in apoptosis
    • Song KS, Kim JS, Yun EJ, Kim YR, Seo KS, Park JH, Jung YJ, Park JI, Kweon GR, Yoon WH, Lim K, Hwang BD,. 2008. Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: The protective role of autophagy in apoptosis. Autophagy 4: 650-658.
    • (2008) Autophagy , vol.4 , pp. 650-658
    • Song, K.S.1    Kim, J.S.2    Yun, E.J.3    Kim, Y.R.4    Seo, K.S.5    Park, J.H.6    Jung, Y.J.7    Park, J.I.8    Kweon, G.R.9    Yoon, W.H.10    Lim, K.11    Hwang, B.D.12
  • 34
    • 2342425038 scopus 로고    scopus 로고
    • Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport
    • Tatebayashi Y, Haque N, Tung YC, Iqbal K, Grundke-Iqbal I,. 2004. Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport. J Cell Sci 117 (Pt 9): 1653-1663.
    • (2004) J Cell Sci , vol.117 , Issue.PART 9 , pp. 1653-1663
    • Tatebayashi, Y.1    Haque, N.2    Tung, Y.C.3    Iqbal, K.4    Grundke-Iqbal, I.5
  • 36
    • 0036725164 scopus 로고    scopus 로고
    • Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation
    • Xie Q, Khaoustov VI, Chung CC, Sohn J, Krishnan B, Lewis DE, Yoffe B,. 2002. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology 36: 592-601.
    • (2002) Hepatology , vol.36 , pp. 592-601
    • Xie, Q.1    Khaoustov, V.I.2    Chung, C.C.3    Sohn, J.4    Krishnan, B.5    Lewis, D.E.6    Yoffe, B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.