SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens

Blood

Volumn 117, Issue 4, 2011, Pages 1319-1328

  Mukhopadhyay, Subhankar ^a   Varin, Audrey ^a,b   Chen, Yunying ^c   Liu, Baoying ^d   Tryggvason, Karl ^c   Gordon, Siamon ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITÉ DE TOURS   (France)

^c KAROLINSKA INSTITUTE   (Sweden)

^d NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CHEMOKINE; CRYOPYRIN; INTERLEUKIN 1BETA; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; RECEPTOR; SCAVENGER RECEPTOR A; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL PERITONITIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; CYTOSOL; IMMUNE RESPONSE; INFLAMMATION; INTERNALIZATION; INTRACELLULAR SPACE; LIGAND BINDING; MENINGOCOCCOSIS; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL;

EID: 79251584028     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-03-276733     Document Type: Article

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