MARCO, an innate activation marker of macrophages, is a class A scavenger receptor for Neisseria meningitidis

European Journal of Immunology

Volumn 36, Issue 4, 2006, Pages 940-949

  Mukhopadhyay, Subhankar ^a   Chen, Yunying ^b   Sankala, Marko ^b   Peiser, Leanne ^a,d   Pikkarainen, Timo ^b   Kraal, Georg ^c   Tryggvason, Karl ^b   Gordon, Siamon ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b KAROLINSKA INSTITUTE   (Sweden)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Bacterial infection; Innate immunity; Macrophage; Phagocytosis

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GENE PRODUCT; MACROPHAGE RECEPTOR WITH COLLAGENOUS DOMAIN PROTEIN; NITRIC OXIDE; PROTEIN MARCO; SCAVENGER RECEPTOR; SCAVENGER RECEPTOR A; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; CONTROLLED STUDY; CORRELATION FUNCTION; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INNATE IMMUNITY; LIGAND BINDING; MOUSE; NEISSERIA MENINGITIDIS; NEISSERIACEAE INFECTION; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION;

ANIMALS; BIOLOGICAL MARKERS; FLOW CYTOMETRY; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEISSERIA MENINGITIDIS; RECEPTORS, IMMUNOLOGIC; SCAVENGER RECEPTORS, CLASS A; TRANSFECTION;

EID: 33645902894     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535389     Document Type: Article

References (35)

1. Mukhopadhyay, S. and Gordon, S., The role of scavenger receptors in pathogen recognition and innate immunity. Immunobiology 2004. 209: 39-49.
2. Peiser, L., Mukhopadhyay, S. and Gordon, S., Scavenger receptors in innate immunity. Curr. Opin. Immunol. 2002. 14: 123-128.
3. Elomaa, O., Kangas, M., Sahlberg, C., Tuukkanen, J., Sormunen, R., Liakka, A., Thesleff, I. et al., Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 1995. 80: 603-609.
4. Kraal, G., van der Laan, L. J., Elomaa, O. and Tryggvason, K., The macrophage receptor MARCO. Microbes Infect. 2000. 2: 313-316.
5. Hampton, R. Y., Golenbock, D. T., Penman, M., Krieger, M. and Raetz, C. R., Recognition and plasma clearance of endotoxin by scavenger receptors. Nature 1991. 352: 342-344.
6. Dunne, D. W., Resnick, D., Greenberg, J., Krieger, M. and Joiner, K. A., The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid. Proc. Natl. Acad. Sci. USA 1994. 91: 1863-1867.
7. Greenberg, J. W., Fischer, W. and Joiner, K. A., Influence of lipoteichoic acid structure on recognition by the macrophage scavenger receptor. Infect. Immun. 1996. 64: 3318-3325.
8. Zhu, F. G., Reich, C. F. and Pisetsky, D. S., The role of the macrophage scavenger receptor in immune stimulation by bacterial DNA and synthetic oligonucleotides. Immunology 2001. 103: 226-234.
9. van der Laan, L. J., Kangas, M., Dopp, E. A., Broug-Holub, E., Elomaa, O., Tryggvason, K. and Kraal, G., Macrophage scavenger receptor MARCO: In vitro and in vivo regulation and involvement in the anti-bacterial host defense. Immunol. Lett. 1997. 57: 203-208.
10. van der Laan, L. J., Dopp, E. A., Haworth, R., Pikkarainen, T., Kangas, M., Elomaa, O., Dijkstra, C. D. et al., Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo. J. Immunol. 1999. 162: 939-947.
11. Seta, N., Granfors, K., Sahly, H., Kuipers, J. G., Song, Y. W., Baeten, D., Veys, E. M. et al., Expression of host defense scavenger receptors in spondylarthropathy. Arthritis Rheum. 2001. 44: 931-939.
12. Sakaguchi, H., Takeya, M., Suzuki, H., Hakamata, H., Kodama, T., Horiuchi, S., Gordon, S. et al., Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice. Lab. Invest. 1998. 78: 423-434.
13. de Villiers, W. J., Fraser, I. P. and Gordon, S., Cytokine and growth factor regulation of macrophage scavenger receptor expression and function. Immunol. Lett. 1994. 43: 73-79.
14. Cornicelli, J. A., Butteiger, D., Rateri, D. L., Welch, K. and Daugherty, A., Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages. J. Lipid Res. 2000. 41: 376-383.
15. Mukhopadhyay, S., Peiser, L. and Gordon, S., Activation of murine macrophages by Neisseria meningitidis and IFN-gamma in vitro: Distinct roles of class A scavenger and Toll-like pattern recognition receptors in selective modulation of surface phenotype. J. Leukoc. Biol. 2004. 76: 577-584.
16. Verheul, A. F., Van Gaans, J. A., Wiertz, E. J., Snippe, H., Verhoef, J. and Poolman, J. T., Meningococcal lipopolysaccharide (LPS)-derived oligosaccharide-protein conjugates evoke outer membrane protein- but not LPS-specific bactericidal antibodies in mice: Influence of adjuvants. Infect. Immun. 1993. 61: 187-196.
17. Pollard, A. J. and Frasch, C., Development of natural immunity to Neisseria meningitidis. Vaccine 2001. 19: 1327-1346.
18. Cartwright, K., introduction and historical aspects. In Cartwright, K. (Ed.) Meningococcal disease. John Wiley and Sons, Chichester 1995, pp 1-20.
19. Read, R. C., Fox, A., Miller, K., Gray, T., Jones, N., Borrows, R., Jones, D. M. and Finch, R. G., Experimental infection of human nasal mucosal explants with Neisseria meningitidis. J. Med. Microbiol. 1995. 42: 353-361.
20. Peiser, L., De Winther, M. P., Makepeace, K., Hollinshead, M., Coull, P., Plested, J., Kodama, T. et al., The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses. Infect. Immun. 2002. 70: 5346-5354.
21. Sankala, M., Brannstrom, A., Schulthess, T., Bergmann, U., Morgunova, E., Engel, J., Tryggvason, K. and Pikkarainen, T., Characterization of recombinant soluble macrophage scavenger receptor MARCO. J. Biol. Chem. 2002. 277: 33378-33385.
22. Fraser, I., Hughes, D. and Gordon, S., Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. Nature 1993. 364: 343-346.
23. Ishiguro, T., Naito, M., Yamamoto, T., Hasegawa, G., Gejyo, F., Mitsuyama, M., Suzuki, H. and Kodama, T., Role of macrophage scavenger receptors in response to Listeria monocytogenes infection in mice. Am. J. Pathol. 2001. 158: 179-188.
24. Thomas, C. A., Li, Y., Kodama, T., Suzuki, H., Silverstein, S. C. and El Khoury, J., Protection from lethal gram-positive infection by macrophage scavenger receptor-dependent phagocytosis. J. Exp. Med. 2000. 191: 147-156.
25. Haworth, R., Platt, N., Keshav, S., Hughes, D., Darley, E., Suzuki, H., Kurihara, Y. et al., The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock. J. Exp. Med. 1997. 186: 1431-1439.
26. Arredouani, M., Yang, Z., Ning, Y., Qin, G., Soininen, R., Tryggvason, K. and Kobzik, L., The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles. J. Exp. Med. 2004. 200: 267-272.
27. Doyle, S. E., O'Connell, R. M., Miranda, G. A., Vaidya, S. A., Chow, E. K., Liu, P. T., Suzuki, S. et al., Toll-like receptors induce a phagocytic gene program through p38. J. Exp. Med. 2004. 199: 81-90.
28. Daugherty, A., Whitman, S. C., Block, A. E. and Rateri, D. L., Polymorphism of class A scavenger receptors in C57BL/6 mice. J. Lipid Res. 2000. 41: 1568-1577.
29. Su, S. H., Chen, H. and Jen, C. J., C57BL/6 and BALB/c bronchoalveolar macrophages respond differently to exercise. J. Immunol. 2001. 167: 5084-5091.
30. Fauve, R. M., Jusforgues, H. and Hevin, B., Maintenance of granuloma macrophages in serum-free medium. J. Immunol. Methods 1983. 64: 345-351.
31. Rabinowitz, S., Horstmann, H., Gordon, S. and Griffiths, G., Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages. J. Cell Biol. 1992. 116: 95-112.
32. Holten, E., Serotypes of Neisseria meningitidis isolated from patients in Norway during the first six months of 1978. J. Clin. Microbiol. 1979. 9: 186-188.
33. van der Ley, P., Kramer, M., Steeghs, L., Kuipers, B., Andersen, S. R., Jennings, M. P., Moxon, E. R. and Poolman, J. T., Identification of a locus involved in meningococcal lipopolysaccharide biosynthesis by deletion mutagenesis. Mol. Microbiol. 1996. 19: 1117-1125.
34. Khoshnoodi, J., Sigmundsson, K., Ofverstedt, L. G., Skoglund, U., Obrink, B., Wartiovaara, J. and Tryggvason, K., Nephrin promotes cell-cell adhesion through homophilic interactions. Am. J. Pathol. 2003. 163: 2337-2346.
35. 15N]nitrate in biological fluids. Anal. Biochem. 1982. 126: 131-138.